Experts and Doctors on dogs in Japan


Locale: Japan
Topic: dogs

Top Publications

  1. Mizumoto A, Fujimura M, Ohtawa M, Ueki S, Hayashi N, Itoh Z, et al. Pituitary adenylate cyclase activating polypeptide stimulates gallbladder motility in conscious dogs. Regul Pept. 1992;42:39-50 pubmed
    ..It was concluded that PACAP27 and PACAP38 stimulate gallbladder motility in conscious dogs through a preganglionic cholinergic mechanism. ..
  2. Sugiyama A, Motomura S, Hashimoto K. Comparison of cardiovascular effects of a novel class Ic antiarrhythmic agent, NIK-244, with those of flecainide in isolated canine heart preparations cross-circulated with a donor dog. Jpn J Pharmacol. 1991;56:1-12 pubmed
  3. Satoh H, Endoh M. Effects of a new cardiotonic agent 1,2-dihydro-6-methyl-2-oxo-5-[imidazo (1,2-a) pyridin-6-yl]-3-pyridine carbonitrile hydrochloride monohydrate (E-1020) on contractile force and cyclic AMP metabolism in canine ventricular muscle. Jpn J Pharmacol. 1990;52:215-24 pubmed
    ..These findings indicate that cyclic AMP is essentially involved in the PIE of E-1020 on the canine ventricular muscle, although the possible involvement of a cyclic AMP-independent mechanism can not be excluded...
  4. Noda A, Okumura I, Ibuki E, Hotta S, Nomoto K, Miyamoto E, et al. Effect of dimethadione derived from repeated oral administration of trimethadione on pancreatic secretion in dogs. Gastroenterol Jpn. 1990;25:613-8 pubmed
  5. Shirahase H, Usui H, Kurahashi K, Fujiwara M, Fukui K. Endothelium-dependent contraction induced by nicotine in isolated canine basilar artery--possible involvement of a thromboxane A2 (TXA2) like substance. Life Sci. 1988;42:437-45 pubmed
  6. Nakanishi S, Hiramoto T, Ahmed N, Nishimoto Y. Almitrine enhances in low dose the reactivity of pulmonary vessels to hypoxia. Respir Physiol. 1988;74:139-50 pubmed
    ..It is supposed that the vasoconstriction induced by Alm may be attributable to a direct effect on pulmonary vessels rather than to a nervous reflex effect. ..
  7. Yamakage M, Matsuzaki T, Tsujiguchi N, Honma Y, Namiki A. Inhibitory effects of diazepam and midazolam on Ca2+ and K+ channels in canine tracheal smooth muscle cells. Anesthesiology. 1999;90:197-207 pubmed
    ..The lack of antagonized effects of their antagonists is related to the non-gamma-aminobutyric acid-mediated electrophysiologic effects of benzodiazepines on airway smooth muscle contractility. ..
  8. Nosaka Y, Tsunokuma M, Hayashi H, Kakudo K. Placement of implants in distraction osteogenesis: a pilot study in dogs. Int J Oral Maxillofac Implants. 2000;15:185-92 pubmed
    ..These results suggest the possibility of shortening the period of implant treatment by using the distraction osteogenesis technique...
  9. Naganobu K, Hasebe Y, Uchiyama Y, Hagio M, Ogawa H. A comparison of distilled water and normal saline as diluents for endobronchial administration of epinephrine in the dog. Anesth Analg. 2000;91:317-21 pubmed

More Information

Publications202 found, 100 shown here

  1. Khatlani T, Ma Z, Okuda M, Onishi T. Molecular cloning and sequencing of canine T-cell costimulatory molecule (CD28). Vet Immunol Immunopathol. 2001;78:341-8 pubmed
    ..The availability of full length canine CD28 will provide a useful molecule for studying its role in dog immune system. ..
  2. Morita T, Shimada A, Takeuchi T, Hikasa Y, Sawada M, Ohiwa S, et al. Cliniconeuropathologic findings of familial frontal lobe epilepsy in Shetland sheepdogs. Can J Vet Res. 2002;66:35-41 pubmed
    ..Based on the distribution of neuronal necrosis and astrocytosis, acute neuronal damage may be related to the superexcitation of neurons following epilepsy. ..
  3. Sato K, Hikasa Y, Morita T, Shimada A, Ozaki K, Kagota K. Secondary erythrocytosis associated with high plasma erythropoietin concentrations in a dog with cecal leiomyosarcoma. J Am Vet Med Assoc. 2002;220:486-90, 464 pubmed
  4. Okamoto H, Takahashi M, Nishizawa T, Tawara A, Fukai K, Muramatsu U, et al. Genomic characterization of TT viruses (TTVs) in pigs, cats and dogs and their relatedness with species-specific TTVs in primates and tupaias. J Gen Virol. 2002;83:1291-7 pubmed publisher
    ..These results indicate that domestic pigs, cats and dogs are naturally infected with species-specific TTVs with small genomic size and suggest a wide distribution of TTVs with extremely divergent genomic sequence and length in animals...
  5. Masuda K, Hashizume C, Kikusui T, Takeuchi Y, Mori Y. Breed differences in genotype and allele frequency of catechol O-methyltransferase gene polymorphic regions in dogs. J Vet Med Sci. 2004;66:183-7 pubmed
    ..These results suggest that the identified polymorphisms will be useful tools in elucidating the genetic background of canine behavioral traits. ..
  6. Kato K, Uchida K, Nibe K, Tateyama S. Immunohistochemical studies on cytokeratin 8 and 18 expressions in canine cutaneous adnexus and their tumors. J Vet Med Sci. 2007;69:233-9 pubmed
    ..Thus, the combination of CK8- and 18-immunostainings may have the utility to confirm the directions of differentiation in canine cutaneous adnexal tumors providing a reliable hallmark for histopathological diagnoses. ..
  7. Uchida Y, Uchida Y, Matsuyama A, Koga A, Kanai M, Sakurai T. Formation of web- and membrane-like structures on the edges of bare-metal coronary stents. Circ J. 2010;74:1830-6 pubmed
    ..W and M were frequently formed on the edges of coronary stents. They were formed with fibrin in the acute phase, whereas this fibrin was replaced by collagen fibers in the chronic phase. ..
  8. Suzuki M, Van Paesschen W, Stalmans I, Horita S, Yamada H, Bergmans B, et al. Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine. Proc Natl Acad Sci U S A. 2010;107:15963-8 pubmed publisher
    ..The immunohistological and functional analyses of these mutants demonstrate that the near total loss of NBCe1 activity in astrocytes can cause migraine potentially through dysregulation of synaptic pH. ..
  9. Iyori K, Hisatsune J, Kawakami T, Shibata S, Murayama N, Ide K, et al. Identification of a novel Staphylococcus pseudintermedius exfoliative toxin gene and its prevalence in isolates from canines with pyoderma and healthy dogs. FEMS Microbiol Lett. 2010;312:169-75 pubmed publisher
    ..1% (3/49). In summary, this newly found orf in S. pseudintermedius encodes a novel exfoliative toxin, which targets a cell-cell adhesion molecule in canine epidermis and might be involved in a broad spectrum of canine pyoderma. ..
  10. Ohkita M, Nagasawa M, Kazutaka M, Kikusui T. Owners' direct gazes increase dogs' attention-getting behaviors. Behav Processes. 2016;125:96-100 pubmed publisher
    ..We suggest that dogs are sensitive to human gazes, and this sensitivity may act as attachment signals to humans, and may contribute to close relationships between humans and dogs. ..
  11. Tanase T, Murakami N, Nagatsu A, Nagai S, Sakakibara J, Ando H, et al. [Studies on cardiac ingredients of plants. X. Preparation of nitrates of tetrahydroproscillaridin and their pharmacological activities]. Yakugaku Zasshi. 1992;112:792-803 pubmed
    ..The positive inotropic effects of mononitrates (11a, 11b, 2a, 2b, 8a, and 8b) were more potent than those of THPs. Nitration of the sugar moiety in THPs resulted in a vascular relaxing effect unobserved in the case of THPs. ..
  12. Takanashi M, Endoh M. Characterization of positive inotropic effect of endothelin on mammalian ventricular myocardium. Am J Physiol. 1991;261:H611-9 pubmed
    ..The receptor density and the PIE of endothelin on mammalian cardiac muscle show a wide range of variation among species...
  13. Minami Y, Toda N. Possible involvement of 5-lipoxygenase products in the generation of endothelium-derived relaxing factor. J Pharmacol Exp Ther. 1989;250:1055-60 pubmed
    ..The findings obtained so far support the idea that lipoxygenase products participate in the generation of EDRF. ..
  14. Kodama T. [Experimental study on the development of endotoxemia in biliary tract infection with special reference to lymphatic pathway at controlled biliary duct pressure]. Nihon Geka Gakkai Zasshi. 1988;89:1978-89 pubmed
    ..At low biliary pressure such as 25 cm saline, endotoxin was detected only in thoracic lymph and endotoxemia did not develop...
  15. Araki J, Takaki M, Namba T, Mori M, Suga H. Ca(2+)-free, high-Ca2+ coronary perfusion suppresses contractility and excitation-contraction coupling energy. Am J Physiol. 1995;268:H1061-70 pubmed
    ..We conclude that the present protocol induced left ventricular contractile failure, primarily involving the suppression of Ca2+ handling energy for excitation-contraction coupling. ..
  16. Tanaka Y, Morimoto K, Ishii K, Nakayama K. Calcium antagonistic vasodilator mechanisms of brovincamine fumarate studied in canine cerebral artery. Arzneimittelforschung. 1994;44:803-8 pubmed
  17. Tamaoki J, Chiyotani A, Takeyama K, Yamauchi F, Tagaya E, Konno K. Relaxation and inhibition of contractile response to electrical field stimulation by Beraprost sodium in canine airway smooth muscle. Prostaglandins. 1993;45:363-73 pubmed
  18. Ishibashi K, Sasaki S, Akiba T, Marumo F. Expression of bone morphogenic protein 7 mRNA in MDCK cells. Biochem Biophys Res Commun. 1993;193:235-9 pubmed
    ..PMA increased BMP7 mRNA at 6h but down-regulated it at 12h and 20h. The result suggests that BMP7 gene expression may be regulated in MDCK cells by PKA and PKC. MDCK cells can be used in further studies of BMP7 regulation. ..
  19. Noda H, Munderloh U, Kurtti T. Endosymbionts of ticks and their relationship to Wolbachia spp. and tick-borne pathogens of humans and animals. Appl Environ Microbiol. 1997;63:3926-32 pubmed
    ..The two symbionts that live in the Malpighian tubules, one closely related to C. burnetii and the other closely related to F. tularensis, appear to be of ancient origin and be widely distributed in ticks. ..
  20. Mutoh T, Tsubone H, Nishimura R, Sasaki N. Responses of laryngeal capsaicin-sensitive receptors to volatile anesthetics in anesthetized dogs. Respir Physiol. 1998;111:113-25 pubmed
  21. Urakami Y, Okuda M, Masuda S, Akazawa M, Saito H, Inui K. Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules. Pharm Res. 2001;18:1528-34 pubmed
  22. Yoshida H, Sugiyama A, Satoh Y, Ishida Y, Yoneyama M, Kugiyama K, et al. Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model. Circ J. 2002;66:758-62 pubmed
    ..These results suggest that IKr channel inhibition by amiodarone with its additional ion channel blocking action may contribute to the prevention of TdP. ..
  23. Shindoh J, Naruse K, Sakai Y, Makuuchi M. Efficacy of immunoadsorbent devices for maintaining hepatic function in ex vivo direct xenogenic hemoperfusion. Int J Artif Organs. 2004;27:294-302 pubmed
  24. Masuda K, Hashizume C, Ogata N, Kikusui T, Takeuchi Y, Mori Y. Sequencing of canine 5-hydroxytriptamine receptor (5-HTR) 1B, 2A, 2C genes and identification of polymorphisms in the 5-HTR1B gene. J Vet Med Sci. 2004;66:965-72 pubmed
  25. Angata T. Molecular diversity and evolution of the Siglec family of cell-surface lectins. Mol Divers. 2006;10:555-66 pubmed
  26. Onishi T, Mori T, Yanagihara M, Furukawa N, Fukuda H. Similarities of the neuronal circuit for the induction of fictive vomiting between ferrets and dogs. Auton Neurosci. 2007;136:20-30 pubmed
    ..All these results in the ferrets are identical with results previously obtained in dogs and cats. Therefore, this suggests that the above neuronal circuit commonly participates in the induction of emesis in these animal species...
  27. Okamoto M, Iseto C, Shibahara T, Sato M, Wandra T, Craig P, et al. Intraspecific variation of Spirometra erinaceieuropaei and phylogenetic relationship between Spirometra and Diphyllobothrium inferred from mitochondrial CO1 gene sequences. Parasitol Int. 2007;56:235-8 pubmed
    ..The phylogenetic relationship between S. erinaceieuropaei and Sparganum proliferum inferred from the CO1 gene clearly confirm the previous opinion that S. proliferum is a distinct species from S. erinaceieuropaei...
  28. Yingsakmongkon S, Miyamoto D, Sriwilaijaroen N, Fujita K, Matsumoto K, Jampangern W, et al. In vitro inhibition of human influenza A virus infection by fruit-juice concentrate of Japanese plum (Prunus mume SIEB. et ZUCC). Biol Pharm Bull. 2008;31:511-5 pubmed
  29. Tsuji N, Miyoshi T, Battsetseg B, Matsuo T, Xuan X, Fujisaki K. A cysteine protease is critical for Babesia spp. transmission in Haemaphysalis ticks. PLoS Pathog. 2008;4:e1000062 pubmed publisher
    ..Our results suggest that longipain is essential for tick survival, and may have a role in controlling the transmission of tick-transmittable Babesia parasites. ..
  30. Omori K, Nakamura T, Kanemaru S, Magrufov A, Yamashita M, Shimizu Y. In situ tissue engineering of the cricoid and trachea in a canine model. Ann Otol Rhinol Laryngol. 2008;117:609-13 pubmed
    ..This study presents the possibility of successful reconstruction of the cricoid and trachea with epithelial regeneration by means of in situ tissue engineering. ..
  31. Mochida K. Anti-influenza virus activity of Myrica rubra leaf ethanol extract evaluated using Madino-Darby canine kidney (MDCK) cells. Biosci Biotechnol Biochem. 2008;72:3018-20 pubmed
    ..Myrica rubra leaf ethanol extract showed anti-influenza virus activity irrespective of the hemagglutinin antigen type in the influenza virus type A (H1N1), its subtype (H3N2), and type B...
  32. Hamamoto T, Yabuki A, Yamato O, Fujiki M, Misumi K, Matsumoto M. Immunohistochemical analysis of cyclooxygenase-2 induction during wound healing in dog skin. Res Vet Sci. 2009;87:349-54 pubmed publisher
    ..In inflammatory cells, COX-positive signals were detected on day 3 only. Here, we clarified the localization and pattern of the induced COX-2 expression during wound healing in dog skin. ..
  33. Ishiwata A, Mimuro J, Mizukami H, Kashiwakura Y, Takano K, Ohmori T, et al. Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice. J Gene Med. 2009;11:1020-9 pubmed publisher
    ..These data suggest that AAV8 vector-mediated liver-restricted cFVIII gene expression is sufficient for immune hypo-responsiveness to transgene-derived cFVIII in fviii(-/-) mice. ..
  34. Takahashi M, Hosoda M, Takahashi H, Todo S. [Comparative studies of paclitaxel injection "SAWAI" and Taxol® Injection on pharmacokinetics in dogs and in vitro/vivo antitumor activities]. Gan To Kagaku Ryoho. 2010;37:1699-706 pubmed
    ..And there are no significant differences between Paclitaxel Injection "SAWAI" and Taxol Injection. These results showed that Paclitaxel Injection "SAWAI" is bioequivalent to Taxol Injection. ..
  35. Satoh S, Takayasu M, Kawasaki K, Ikegaki I, Hitomi A, Yano K, et al. Antivasospastic effects of hydroxyfasudil, a Rho-kinase inhibitor, after subarachnoid hemorrhage. J Pharmacol Sci. 2012;118:92-8 pubmed
    ..The results also suggest that hydroxyfasudil contributes to the potency of fasudil to prevent cerebral vasospasm and hyperviscosity and suggest the potential utility of hydroxyfasudil as a therapeutic agent for patients with SAH. ..
  36. Kitahara M, Miyagawa S, Fukushima S, Saito A, Shintani A, Akita T, et al. Biodegradable vs Nonbiodegradable Cardiac Support Device for Treating Ischemic Cardiomyopathy in a Canine Heart. Semin Thorac Cardiovasc Surg. 2017;29:51-61 pubmed publisher
    ..02). The cardiac support devices made of biodegradable material were more effective in improving systolic function, with preservation of diastolic function in the canine infarct heart, than devices made of nonbiodegradable material. ..
  37. Noda A, Okumura I, Kato H, Ibuki E, Tamada M, Watanabe T. Pancreatic excretion of dimethadione and trimethadione by repeated oral administration of trimethadione in dogs. Digestion. 1990;46:19-26 pubmed
    ..Pancreatic DMO clearance (DMO output/DMO concentration in plasma) increased, depending on the flow rate, the bicarbonate concentration, and pH of pancreatic juice. Pancreatic excretion of TMO was zero or extremely low. ..
  38. Namba T, Takaki M, Araki J, Ishioka K, Akashi T, Matsushita T, et al. Left ventricular ORS widening decreases Emax without lowering VO2-PVA relation in dog hearts. Jpn J Physiol. 1993;43:379-87 pubmed
    ..We suspected the unusual observation to reflect no change in myocardial contractility despite ventricular asynchrony augmented by an intraventricular conduction defect. ..
  39. Sakai K, Zhang S, Ureshino H, Tomiyasu S, Sumikawa K. Interaction of isoflurane and cromakalim, a KATP channel opener, on coronary and systemic haemodynamics in chronically instrumented dogs. Acta Anaesthesiol Scand. 2000;44:1122-7 pubmed
    ..The present study was carried out to determine the haemodynamic actions of cromakalim, a KATP channel opener, under the conscious state and during isoflurane anaesthesia in chronically instrumented dogs...
  40. Tayama N, Chan R, Kaga K, Titze I. Geometric characterization of the laryngeal cartilage framework for the purpose of biomechanical modeling. Ann Otol Rhinol Laryngol. 2001;110:1154-61 pubmed
    ..The results are useful for constructing quantitative biomechanical models of vocal fold vibration and posturing (abduction and adduction), eg, continuum mechanical models and finite-element models of the vocal folds. ..
  41. Sugiura K, Nishikawa M, Ishiguro K, Tajima T, Inaba M, Torii R, et al. Effect of ovarian hormones on periodical changes in immune resistance associated with estrous cycle in the beagle bitch. Immunobiology. 2004;209:619-27 pubmed
    ..This marked decrease of immune resistance allows the expansion of E. coli, which enter the uterine cavity through the loosened cervical canal during estrus, leading to pyometra onset. ..
  42. Kim S, Adachi Y. Biological and genetic classification of canine intestinal lactic acid bacteria and bifidobacteria. Microbiol Immunol. 2007;51:919-28 pubmed
    ..The sequences of the isolates also showed high levels of similarity to those of the reference strains registered previously in the DDBJ and the similarity was above 97.2%. Their partial 16S rRNA genes were registered in the DDBJ. ..
  43. Hirakawa N, Morimoto M, Totoki T. Sympathetic innervation of the young canine heart using antero- and retrograde axonal tracer methods. Brain Res Bull. 1993;31:673-80 pubmed
    ..The labeled fibers were also observed around the coronary arteries. ..
  44. Inoue M, Nakamura T, Shigeno K, Ueda H, Tamura N, Fukuda S, et al. Regeneration of the junctional epithelium and connective tissue after transplantation of detergent-processed allo-teeth. Int J Artif Organs. 2000;23:845-51 pubmed
    ..Use of the acellular periodontal ligament as an extracellular matrix may facilitate regeneration of host periodontal ligament tissue, thus contributing to recovery of host immunological defense and long-term oral function...
  45. Yui N, Okutsu R, Sohara E, Rai T, Ohta A, Noda Y, et al. FAPP2 is required for aquaporin-2 apical sorting at trans-Golgi network in polarized MDCK cells. Am J Physiol Cell Physiol. 2009;297:C1389-96 pubmed publisher
    ..These results suggest that FAPP2 is necessary to generate AQP2-bearing vesicles at trans-Golgi that will undergo phosphorylation by PKA in subapical regions...
  46. Nagasaka Y, Oda K, Iwatsubo T, Kawamura A, Usui T. Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier. Biopharm Drug Dispos. 2012;33:304-15 pubmed publisher
    ..However, interactions at the intestinal absorption process may be of concern...
  47. Onda M, Inui S, Maeda K, Suzuki M, Takahashi E, Sakaguchi N. Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway. Genomics. 1997;46:373-8 pubmed
    ..The anti-human alpha 4 antibody detected a 45-kDa protein in human lymphoid cell lines. Moreover, human alpha 4 (IGBP1) gene is located at q13.1-q13.3 on chromosome X. ..
  48. Choi Y, Ishiguro N, Shinagawa M, Kim C, Okamoto Y, Minami S, et al. Molecular structure of canine LINE-1 elements in canine transmissible venereal tumor. Anim Genet. 1999;30:51-3 pubmed
    ..The TVT-LINE elements were composed of 416 bp inverse sequences homologous to the complementary strand of the LINE-1, a 5-bp deletion and 962-bp sequences homologous to the 3' region of the LINE-1. ..
  49. Okamura T, Ayajiki K, Fujioka H, Shinozaki K, Toda N. Neurogenic cerebral vasodilation mediated by nitric oxide. Jpn J Pharmacol. 2002;88:32-8 pubmed
    ..Our findings suggest that the nitroxidergic (nitrergic) nerve plays a physiologically important role to maintain a steady blood supply to the brain. ..
  50. Ohshima T, Kishi M, Mochizuki M. Sequence analysis of an Asian isolate of minute virus of canines (canine parvovirus type 1). Virus Genes. 2004;29:291-6 pubmed
    ..These results suggest that MVC together with BPV can possibly be classified into a new clade in the Parvovirinae subfamily. ..
  51. Tojinbara K, Yamada A, Kakitani I, Kwan N, Sugiura K. Estimating the probability distribution of the incubation period for rabies using data from the 1948-1954 rabies epidemic in Tokyo. Prev Vet Med. 2016;123:102-105 pubmed publisher
    ..30 (95% CI: 23.46-31.55) days and standard deviation of 20.20 (15.27-26.31) days. There were no significant differences between the incubation periods for dogs and cats, or between those for male and female dogs. ..
  52. Omori K, Nakamura T, Kanemaru S, Kojima H, Magrufov A, Hiratsuka Y, et al. Cricoid regeneration using in situ tissue engineering in canine larynx for the treatment of subglottic stenosis. Ann Otol Rhinol Laryngol. 2004;113:623-7 pubmed
    ..Confluent regeneration of the epithelium over the scaffold and good incorporation of the scaffold mesh into the host tissue were observed after surgery. ..
  53. Hwang S, Yamasaki M, Nakamura K, Sasaki N, Murakami M, Wickramasekara Rajapakshage B, et al. Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro. J Vet Med Sci. 2010;72:765-71 pubmed
    ..These results indicated that the DA-resistant B. gibsoni strain could have resistance not only to DA, but also to other anti-babesial drugs. In conclusion, we successfully developed a DA-resistant B. gibsoni strain in vitro. ..
  54. Shinkai H, Nishikawa M, Sato Y, Toi K, Kumashiro I, Seto Y, et al. N-(cyclohexylcarbonyl)-D-phenylalanines and related compounds. A new class of oral hypoglycemic agents. 2. J Med Chem. 1989;32:1436-41 pubmed
    ..6 mg/kg in fasted normal mice. ..
  55. Morita T, Ando M, Kihara K, Oshima H. Function and distribution of autonomic receptors in canine ureteral smooth muscle. Neurourol Urodyn. 1994;13:315-21 pubmed
    ..It is also suggested that prostaglandins directly affect canine ureteral contraction. ..
  56. Yamamoto Y, Ootsuka T, Atoji Y, Suzuki Y. Tyrosine hydroxylase- and neuropeptides-immunoreactive nerves in canine trachea. Am J Vet Res. 2000;61:1380-3 pubmed
    ..Complex innervation, including catecholamine- and neuropeptide-containing nerves, which may be related to regulation of muscle contraction and glandular secretion, are found in canine tracheas. ..
  57. Suzuki M, Kimura M, Imaoka K, Yamada A. Prevalence of Capnocytophaga canimorsus and Capnocytophaga cynodegmi in dogs and cats determined by using a newly established species-specific PCR. Vet Microbiol. 2010;144:172-6 pubmed publisher
    ..Our findings suggest the importance of informing people who belong to high-risk groups as well as health care workers on C. canimorsus infection and its potential risk to people particularly to those who are immunocompromised...
  58. Nitobe T, Harata S, Okamoto Y, Nakamura T, Endo M. Degradation and biosynthesis of proteoglycans in the nucleus pulposus of canine intervertebral disc after chymopapain treatment. Spine (Phila Pa 1976). 1988;13:1332-9 pubmed
    ..It was concluded that, following chemonucleolysis with chymopapain, the water-binding capacity of the nucleus pulposus recovered, but that the regenerated nucleus pulposus differed biochemically from the original. ..
  59. Takeda K, Tanaka N, Nishi S, Asada A. The application of the hemoglobin saturation sensor and indocyanine green (ICG) for blood flow measurement. Osaka City Med J. 2006;52:21-7 pubmed
    ..Application of a hemoglobin saturation sensor and ICG to blood flow measurement was reliable and useful in both circuit and animal models. This method may be clinically useful for measurement of blood flow. ..
  60. Togo T. Cell membrane disruption stimulates NO/PKG signaling and potentiates cell membrane repair in neighboring cells. PLoS ONE. 2012;7:e42885 pubmed publisher
    ..Together, these results suggest that the nitric oxide/PKG pathway stimulates CREB phosphorylation in neighboring cells so that subsequent cell membrane disruptions of the neighboring cells reseal more quickly. ..
  61. Okamura T, Inoue S, Minami Y, Okunishi H, Toda N. Role of endothelium in the response to prostaglandin H2 in isolated dog arteries. Jpn J Pharmacol. 1989;49:511-21 pubmed
    ..However, production of PGI2 from PGH2 in endothelial and subendothelial tissues do not appear to differ. ..
  62. Kushiku K, Araki Y, Furukawa T, Iwasa T, Inoue N, Miyamoto E. Increment of calmodulin in proportion to enhancement of non-nicotinic responses after preganglionic stimulation of the dog cardiac sympathetic ganglia. J Pharmacol Exp Ther. 1988;245:311-8 pubmed
    ..The inhibition of endogenous protein synthesis by cycloheximide, 2.5 or 5 mg/kg i.v. 6 hr before surgical procedures, strongly inhibited development of the enhancement in responses to angiotensin II.(ABSTRACT TRUNCATED AT 250 WORDS)..
  63. Wada T, Yao H, Miyamoto T, Mukai S, Yamamura M. Prevention and detection of spinal cord injury during thoracic and thoracoabdominal aortic repairs. Ann Thorac Surg. 2001;72:80-4; discussion 85 pubmed
    ..Maintaining spinal cord perfusion pressure at more than 40 mm Hg by increasing mean distal aortic pressure or withdrawal of cerebrospinal fluid is valuable for preventing paraplegia. ..
  64. Toba T, Nakamura T, Lynn A, Matsumoto K, Fukuda S, Yoshitani M, et al. Evaluation of peripheral nerve regeneration across an 80-mm gap using a polyglycolic acid (PGA)--collagen nerve conduit filled with laminin-soaked collagen sponge in dogs. Int J Artif Organs. 2002;25:230-7 pubmed
    ..Walking patterns had returned to near-normal 12 months after implantation. Use of this nerve conduit can lead to peripheral nerve elongation and favorable functional recovery across a wider nerve gap...
  65. Miyazaki T, Fujiki H, Yamamura Y, Nakamura S, Mori T. Tolvaptan, an orally active vasopressin V(2)-receptor antagonist - pharmacology and clinical trials. Cardiovasc Drug Rev. 2007;25:1-13 pubmed
    ..Furthermore, tolvaptan is also expected to be effective in the treatment of PKD. ..
  66. Igarashi Y, Takeshima T, Tauchi K, Tanaka K, Ogawa S. [Identifying the fluorescent body (F-body) with quinacrine mustard staining of canine]. Jikken Dobutsu. 1989;38:263-7 pubmed
    ..The examination using a reflected fluorescent microscope revealed that the same F-body in human was present in both spermatozoon (20.1-39.7%) and interphase of lymphocyte (0.37.2%) of male origin. ..
  67. Taya S, Yamamoto T, Kanai Azuma M, Wood S, Kaibuchi K. The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin. Genes Cells. 1999;4:757-67 pubmed
    ..These results indicate that Fam interacts with and stabilizes beta-catenin in vivo, presumably through the deubiquitination of beta-catenin. ..
  68. Watanabe M, Sugano S, Togashi T, Imai J, Uchida K, Yamaguchi R, et al. Molecular cloning and phylogenetic analysis of canine beta-casein. DNA Seq. 2000;11:295-300 pubmed
    ..A 1.2-kb mRNA was detected in mammary tissue by Northern blot analysis. Phylogenetic analysis revealed that canine beta-casein formed a branch with lesser panda and snow leopard, which were grouped into carnivore. ..
  69. Oyamada M, Davoust B, Boni M, Dereure J, Bucheton B, Hammad A, et al. Detection of Babesia canis rossi, B. canis vogeli, and Hepatozoon canis in dogs in a village of eastern Sudan by using a screening PCR and sequencing methodologies. Clin Diagn Lab Immunol. 2005;12:1343-6 pubmed
    ..Among 78 dogs, 5 were infected with Babesia canis rossi and 2 others were infected with B. canis vogeli. Thirty-three dogs were positive for Hepatozoon. Hepatozoon canis was detected by sequence analysis. ..
  70. Mizumura K, Koda H. Potentiation and suppression of the histamine response by raising and lowering the temperature in canine visceral polymodal receptors in vitro. Neurosci Lett. 1999;266:9-12 pubmed
    ..Sci. Incorp. Heart, 3 (1937) 377-386) cannot be explained by the noxious heat-induced facilitation of the peripheral receptor response reported in this paper. ..
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