Experts and Doctors on dna polymerase iii in Italy


Locale: Italy
Topic: dna polymerase iii

Top Publications

  1. Longhese M, Plevani P, Lucchini G. Replication factor A is required in vivo for DNA replication, repair, and recombination. Mol Cell Biol. 1994;14:7884-90 pubmed
    ..Moreover, genetic evidence indicate that p70 interacts both with the DNA polymerase alpha-primase complex and with DNA polymerase delta. ..
  2. Stefan A, Tabler M, Hochkoeppler A. Efficient silencing of the gene coding for the epsilon subunit of DNA polymerase III in Escherichia coli is triggered by antisense RNAs featuring stability in vivo. FEMS Microbiol Lett. 2007;270:277-83 pubmed
    ..Moreover, the in vivo concentration of an antisense transcript was positively correlated to its silencing effectiveness. ..
  3. Maga G, van Loon B, Crespan E, Villani G, Hubscher U. The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1. J Biol Chem. 2009;284:14267-75 pubmed publisher
    ..Our data identify a previously unnoticed deleterious effect of the AP site lesion on normal cell metabolism and suggest the existence of a novel repair pathway that might be important in preventing replication fork stalling. ..
  4. Kolinjivadi A, Sannino V, De Antoni A, Zadorozhny K, Kilkenny M, Técher H, et al. Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments. Mol Cell. 2017;67:867-881.e7 pubmed publisher
    ..These results indicate that Brca2 and Rad51 prevent formation of abnormal DNA replication intermediates, whose processing by Smarcal1 and Mre11 predisposes to genome instability. ..