Genomes and Genes
Experts and Doctors on dna polymerase beta in France
Topic: dna polymerase beta
- Rouillon C, Henneke G, Flament D, Querellou J, Raffin J. DNA polymerase switching on homotrimeric PCNA at the replication fork of the euryarchaea Pyrococcus abyssi. J Mol Biol. 2007;369:343-55 pubmed..Then, Pol D is displaced by Pol B to perform processive DNA synthesis, at least on the leading strand...
- Bertocci B, De Smet A, Weill J, Reynaud C. Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo. Immunity. 2006;25:31-41 pubmed
- Delmas S, Matic I. Interplay between replication and recombination in Escherichia coli: impact of the alternative DNA polymerases. Proc Natl Acad Sci U S A. 2006;103:4564-9 pubmed
- Blanca G, Villani G, Shevelev I, Ramadan K, Spadari S, Hubscher U, et al. Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation. Biochemistry. 2004;43:11605-15 pubmed
- Marsin S, Vidal A, Sossou M, Menissier de Murcia J, Le Page F, Boiteux S, et al. Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1. J Biol Chem. 2003;278:44068-74 pubmed
- Becherel O, Fuchs R, Wagner J. Pivotal role of the beta-clamp in translesion DNA synthesis and mutagenesis in E. coli cells. DNA Repair (Amst). 2002;1:703-8 pubmed..Thus, in addition to its crucial role as the processivity factor of the PolIII replicase, the beta-clamp plays a pivotal role during the TLS process. ..
- Servant L, Cazaux C, Bieth A, Iwai S, Hanaoka F, Hoffmann J. A role for DNA polymerase beta in mutagenic UV lesion bypass. J Biol Chem. 2002;277:50046-53 pubmed..These data support a biological role of pol beta in UV lesion bypass and suggest that deregulated pol beta may enhance UV-induced genetic instability. ..
- Schreiber V, Ame J, Dolle P, Schultz I, Rinaldi B, Fraulob V, et al. Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J Biol Chem. 2002;277:23028-36 pubmed