Experts and Doctors on dexamethasone in South Korea

Summary

Locale: South Korea
Topic: dexamethasone

Top Publications

  1. Choung Y, Park K, Shin Y, Cho M. Intratympanic dexamethasone injection for refractory sudden sensorineural hearing loss. Laryngoscope. 2006;116:747-52 pubmed
    ..There were no definite prognostic factors between the patients who responded to ITDI and those who did not. ITDI may be a simple and effective therapy for patients with refractory SSNHL. ..
  2. Gurusamy M, Nasseri S, Lee H, Jung B, Lee D, Khang G, et al. Kinin B1 receptor antagonist BI113823 reduces allergen-induced airway inflammation and mucus secretion in mice. Pharmacol Res. 2016;104:132-9 pubmed publisher
    ..BI113823 effectively reduced OVA-induced inflammatory cell, mediator and signaling pathways equal to or greater than that seen with steroids in a mouse asthma model. BI113823 might be useful in modulating inflammation in asthma. ..
  3. Yang Y, Ahn T, Lee J, Moon C, Kim S, Jun W, et al. Protective effects of Pycnogenol on carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats. Food Chem Toxicol. 2008;46:380-7 pubmed
  4. Yun S, Yoon H, Jeong S, Chung Y. Glucocorticoid induces apoptosis of osteoblast cells through the activation of glycogen synthase kinase 3beta. J Bone Miner Metab. 2009;27:140-8 pubmed publisher
    ..In contrast, the inhibition of p38-MAPK by inhibitor (SB203580) or siRNA did not decrease, but increase apoptosis. These results suggest that Dex-mediated apoptosis of osteoblasts is facilitated by GSK3beta, but prevented by p38-MAPK. ..
  5. Dimopoulos M, Cheung M, Roussel M, Liu T, Gamberi B, Kolb B, et al. Impact of renal impairment on outcomes with lenalidomide and dexamethasone treatment in the FIRST trial, a randomized, open-label phase 3 trial in transplant-ineligible patients with multiple myeloma. Haematologica. 2016;101:363-70 pubmed publisher
    ..Trial registration: ClinicalTrials.gov (NCT00689936); EudraCT (2007-004823-39). Funding: Intergroupe Francophone du Myélome and the Celgene Corporation. ..
  6. Bong J, Seol M, Kim H, Han O, Back K, Baik M. The 24p3 gene is induced during involution of the mammary gland and induces apoptosis of mammary epithelial cells. Mol Cells. 2004;17:29-34 pubmed
    ..This study provides evidence that overexpression of 24p3 gene can induce apoptosis of mammary epithelial cells. ..
  7. Park J, Kim M, Na G, Jeon I, Kwon Y, Kim J, et al. Glucocorticoids modulate NF-kappaB-dependent gene expression by up-regulating FKBP51 expression in Newcastle disease virus-infected chickens. Mol Cell Endocrinol. 2007;278:7-17 pubmed
    ..These results suggest that systemic elevation of FKBP51 in NDV-infected chickens activates NF-kappaB, which cooperates with other factors to regulate the expression of NF-kappaB-dependent genes. ..
  8. Lim Y, Na H, Yun Y, Choi I, Oh J, Rhee J, et al. Suppressive effects of ginsan on the development of allergic reaction in murine asthmatic model. Int Arch Allergy Immunol. 2009;150:32-42 pubmed publisher
    ..Lastly, ginsan inhibited the allergic reaction aggravated by COX inhibitor (indomethacin). Ginsan has anti-asthmatic effects, which seem to be partially mediated by enhancing the synthesis of COX gene products. ..
  9. Jeon J, Kim N, Kim S, Kang N, Novak O, Ku S, et al. A subset of cytokinin two-component signaling system plays a role in cold temperature stress response in Arabidopsis. J Biol Chem. 2010;285:23371-86 pubmed publisher
    ..These results suggest that AHK2 and AHK3 and the cold-inducible A-type ARRs play a negative regulatory role in cold stress signaling via inhibition of ABA response, occurring independently of the cold acclimation pathway. ..

More Information

Publications14

  1. Yun S, Ryu J, Han H. Involvement of ?1-integrin via PIP complex and FAK/paxillin in dexamethasone-induced human mesenchymal stem cells migration. J Cell Physiol. 2011;226:683-92 pubmed publisher
    ..In conclusion, DEX partially stimulates hMSC migration by the expression of ?1-integrin through formation of a PINCH-1/2/ILK/?-parvin complex (PIP complex), and FAK and paxillin expression. ..
  2. Son J, Kim S, Oh J, Appleford M, Oh S, Ong J, et al. Hydroxyapatite/polylactide biphasic combination scaffold loaded with dexamethasone for bone regeneration. J Biomed Mater Res A. 2011;99:638-47 pubmed publisher
    ..Therefore, it was concluded that this functionally graded scaffold is similar to natural bone and represents a potential bone-substitute material. ..
  3. Jeon J, Kim J. Arabidopsis response Regulator1 and Arabidopsis histidine phosphotransfer Protein2 (AHP2), AHP3, and AHP5 function in cold signaling. Plant Physiol. 2013;161:408-24 pubmed publisher
    ..We further identified a cold transcriptome affected by ahk2 ahk3 mutations by microarray analysis, revealing a new cold-responsive gene network regulated downstream of AHK2 and AHK3. ..
  4. Choi H, Baik M, Myung K. Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones. Cell Biol Int. 2005;29:177-9 pubmed
    ..Expression was markedly increased in differentiated cells and it was up-regulated 2-fold in cells induced to differentiate with dexamethasone. ..
  5. Ku S, Park J, Ha S, Kim J. Overexpression of IAA1 with domain II mutation impairs cell elongation and cell division in inflorescences and leaves of Arabidopsis. J Plant Physiol. 2009;166:548-53 pubmed publisher
    ..In addition, the formation of both phloem and xylem in leaves and stems was also impaired in a DEX-dependent manner, indicating a potential involvement of IAA1 in vascular development. ..