Experts and Doctors on complementary dna in Japan


Locale: Japan
Topic: complementary dna

Top Publications

  1. Nomura M, Takihara Y, Shimada K. Isolation of a cDNA clone encoding mouse 3-hydroxyacyl CoA dehydrogenase. Gene. 1995;160:309-10 pubmed
    ..1.1.35). This clone can be used to elucidate the regulatory mechanism of HCDH gene expression in mammals. ..
  2. Matsuoka K, Taoka M, Satozawa N, Nakayama H, Ichimura T, Takahashi N, et al. A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons. Proc Natl Acad Sci U S A. 1994;91:9670-4 pubmed
    ..The structural characteristics, localization, and the stage- and cell type-specific expression suggest a potential role of LANP in a signal transduction pathway that directs differentiation of cerebellar neurons. ..
  3. Masuno M, Shimozawa N, Suzuki Y, Kondo N, Orii T, Tsukamoto T, et al. Assignment of the human peroxisome assembly factor-1 gene (PXMP3) responsible for Zellweger syndrome to chromosome 8q21.1 by fluorescence in situ hybridization. Genomics. 1994;20:141-2 pubmed
  4. NĂ¼sing R, Hirata M, Kakizuka A, Eki T, Ozawa K, Narumiya S. Characterization and chromosomal mapping of the human thromboxane A2 receptor gene. J Biol Chem. 1993;268:25253-9 pubmed
    ..Chromosomal localization was carried out by fluorescence in situ hybridization of cloned genomic DNA to the metaphase chromosome. The gene was assigned to 19p13.3 of human chromosome. ..
  5. Chinen K, Takahashi E, Nakamura Y. Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3' untranslated region. Cytogenet Cell Genet. 1996;73:218-23 pubmed
    ..elegans, evolutionary conservation is indicated. SEC14L, which was expressed in all human tissues examined, was localized to chromosome bands 17q25.1 --> q25.2 by fluorescence in situ hybridization. ..
  6. Endo Y, Sato Y, Matsushita M, Fujita T. Cloning and characterization of the human lectin P35 gene and its related gene. Genomics. 1996;36:515-21 pubmed
    ..Both genes were assigned to a closely related region of chromosome 9 at 9q34. ..
  7. Ogasa H, Noma T, Murata H, Kawai S, Nakazawa A. Cloning of a cDNA encoding the human transforming growth factor-beta type II receptor: heterogeneity of the mRNA. Gene. 1996;181:185-90 pubmed
    ..The heterogeneity of TGF-beta IIR molecules could be derived from alternative splicing and might elicit specific TGF-beta receptor functions. ..
  8. Urao T, Yamaguchi Shinozaki K, Mitsukawa N, Shibata D, Shinozaki K. Molecular cloning and characterization of a gene that encodes a MYC-related protein in Arabidopsis. Plant Mol Biol. 1996;32:571-6 pubmed
  9. Aizawa S, Satoh H, Horie R, Ito K, Choi S, Takeuchi H, et al. Cloning and characterization of a cDNA for rat CD30 homolog and chromosomal assignment of the genomic gene. Gene. 1996;182:155-62 pubmed
    ..2, and appeared to correspond to human 1p36, where human CD30 has been mapped. The identification and characterization of the rat counterpart of human CD30 will facilitate studies of the biological function of this molecule. ..

More Information

Publications207 found, 100 shown here

  1. Watanabe F, Sakai A, Furuya E. Novel isoforms of rat brain fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase are generated by tissue-specific alternative splicing. J Neurochem. 1997;69:1-9 pubmed
    ..High-level expression of the gene was also observed by northern blot analysis in skeletal muscle. However, the pattern of alternative splicing was different from that of brain, and only four isoforms were detected in skeletal muscle. ..
  2. Furukawa S, Tanaka H, Nakazawa H, Ishibashi J, Shono T, Yamakawa M. Inducible gene expression of moricin, a unique antibacterial peptide from the silkworm (Bombyx mori). Biochem J. 1999;340 ( Pt 1):265-71 pubmed
    ..An electrophoretic-mobility-shift assay revealed that there are bacterial LPS-inducible nuclear proteins that can bind to the kappaB site and other sites in the regulatory region...
  3. Andoh K, Piao J, Terashima K, Nakamura H, Sano K. Genomic structure and promoter analysis of the ecto-phosphodiesterase I gene (PDNP3) expressed in glial cells. Biochim Biophys Acta. 1999;1446:213-24 pubmed
    ..A gel shift assay demonstrated that 9L nuclear extract contains proteins that bind to this region. ..
  4. Ueda T, Sakagami H, Abe K, Oishi I, Maruo A, Kondo H, et al. Distribution and intracellular localization of a mouse homologue of Ca2+/calmodulin-dependent protein kinase Ibeta2 in the nervous system. J Neurochem. 1999;73:2119-29 pubmed
    ..In addition, mCaMKI/beta2 proteins are localized to the cytoplasm and nuclei, but not to nucleoli, suggesting that mCaMKIbeta2 proteins might be involved in the cytoplasmic and nuclear signal transduction of the nervous system. ..
  5. Nishimura K, Kashiwagi K, Matsuda Y, Janne O, Igarashi K. Gene structure and chromosomal localization of mouse S-adenosylmethionine decarboxylase. Gene. 1999;238:343-50 pubmed
    ..Lower concentrations of polyamines affect both stimulation and inhibition of AdoMetDC synthesis, through the uORF in the mRNA, than affect general protein synthesis. ..
  6. Kawano T, Takuwa K, Kuniyoshi H, Juni N, Nakajima T, Yamamoto D, et al. Cloning and characterization of a Drosophila melanogaster cDNA encoding a glutamate transporter. Biosci Biotechnol Biochem. 1999;63:2042-4 pubmed
    ..Northern blot analysis showed that the transcript increased in amount developmentally. This expression pattern is different from those of Drosophila glutamate receptors...
  7. Mizutani Y, Tamiya Koizumi K, Irie F, Hirabayashi Y, Miwa M, Yoshida S. Cloning and expression of rat neutral sphingomyelinase: enzymological characterization and identification of essential histidine residues. Biochim Biophys Acta. 2000;1485:236-46 pubmed
    ..This enzyme also catalyzed the hydrolysis of lyso-platelet activating factor to yield 1-alkylglycerol at a rate that is slightly lower than that with sphingomyelin. ..
  8. Kawamura H, Tomozoe Y, Akagi T, Kamei D, Ochiai M, Yamada M. Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA. J Biol Chem. 2002;277:2732-9 pubmed
    ..UV cross-linking revealed the increased occurrence of JKTBP1 directly interacting with poly(A)(+) RNA in the cytoplasm following actinomycin D treatment. We discuss a role of JKTBP in mRNA nuclear export. ..
  9. Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, et al. Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem. 2003;278:2461-8 pubmed
    ..In conclusion, replenishment of globular adiponectin may provide a novel treatment modality for both type 2 diabetes and atherosclerosis. ..
  10. Muneta Y, Kikuma R, Uenishi H, Hoshino T, Yoshihara K, Tanaka M, et al. Molecular cloning, chromosomal location, and biological activity of porcine interleukin-21. J Vet Med Sci. 2004;66:269-75 pubmed
    ..coli induced dose-dependent proliferation and IFN-gamma production from a human NK cell line, NK0. The porcine IL-21 identified in this study will be helpful for the enhancement of innate immune responses of pigs. ..
  11. Katoh M, Katoh M. Identification and characterization of human PDZRN4L gene and mouse Pdzrn4l gene in silico. Int J Mol Med. 2004;13:923-7 pubmed
    ..9% total-amino-acid identity with human PDZRN4S. PDZ, PR34H1 and PR34H2 domains were conserved between PDZRN4L and PDZRN4S. This is the first report on human PDZRN4L and mouse Pdzrn4l genes. ..
  12. Katoh M, Katoh M. Identification and characterization of human FHDC1, mouse Fhdc1 and zebrafish fhdc1 genes in silico. Int J Mol Med. 2004;13:929-34 pubmed
    ..This is the first report on the identification and characterization of the human FHDC1, mouse Fhdc1 and zebrafish fhdc1 genes. ..
  13. Wang Y, Suzuki H, Yokoo T, Tada Iida K, Kihara R, Miura M, et al. WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney. Biochem Biophys Res Commun. 2004;324:1053-8 pubmed
    ..The expression pattern may also suggest the possible importance of WGEF in the understanding of diseases based on metabolic disorder. ..
  14. Shigenobu S, Arita K, Kitadate Y, Noda C, Kobayashi S. Isolation of germline cells from Drosophila embryos by flow cytometry. Dev Growth Differ. 2006;48:49-57 pubmed
    ..This technique opens the way for genome-wide transcriptome analysis of germline cells. In a pilot experiment, we generated a cDNA library from purified embryonic gonad and identified a novel germline-specific gene, RpL22-like. ..
  15. Sarashina I, Yamaguchi H, Haga T, Iijima M, Chiba S, Endo K. Molecular evolution and functionally important structures of molluscan Dermatopontin: implications for the origins of molluscan shell matrix proteins. J Mol Evol. 2006;62:307-18 pubmed publisher
    ..These results suggest that the dermatopontin genes were co-opted for molluscan calcification at least twice independently after the divergence of basommatophoran and stylommatophoran lineages, or more recently than we have expected...
  16. Furukawa S, Tanaka H, Ishibashi J, Imanishi S, Yamakawa M. Functional characterization of a cactus homolog from the silkworm Bombyx mori. Biosci Biotechnol Biochem. 2009;73:2665-70 pubmed
    ..These results suggest that BmCactus is involved in the Toll signal transduction pathway in B. mori. ..
  17. Fujita M, Fujii H, Kanda T, Sato E, Hatakeyama K, Ono T. Molecular cloning, expression, and characterization of a human intestinal 15-kDa protein. Eur J Biochem. 1995;233:406-13 pubmed
    ..Comparison of the structural features of human I-15P and human L-FABP suggested that loss of a long alpha-helix region and hydrophobic profile of I-15P may be attributable to a unique ligand-binding specificity of I-15P. ..
  18. Matsumoto M, Kamohara M, Sugimoto T, Hidaka K, Takasaki J, Saito T, et al. The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors. Gene. 2000;248:183-9 pubmed
    ..1-5p14. Transient expression of SALPR in COS-1 cells did not produce any binding sites for somatostatin or angiotensin II, indicating the necessity for further study to discover its ligand and physiological significance. ..
  19. Maruyama H, Oguma K, Maeda S, Kano R, Tsujimoto H, Watari T, et al. Molecular cloning of canine thrombomodulin cDNA and expression in normal tissues. J Vet Med Sci. 2004;66:1423-7 pubmed
    ..The present results provide valuable data for research into canine coagulation disorders. ..
  20. Nomura M, Takihara Y, Yasunaga T, Shimada K. One of the retinoic acid-inducible cDNA clones in mouse embryonal carcinoma F9 cells encodes a novel isoenzyme of fructose 1,6-bisphosphatase. FEBS Lett. 1994;348:201-5 pubmed
    ..These findings indicate that the Rae-30 cDNA encodes a novel isoenzyme of FBPase, which is likely to be involved in early differentiation in mammalian cells. ..
  21. Sasaki K, Kurata K, Funayama K, Nagata M, Watanabe E, Ohta S, et al. Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. J Biol Chem. 1994;269:14730-7 pubmed
    ..These results suggest that Fuc-TVII may participate in the biosynthesis of the selectin ligands. ..
  22. Orii K, Aoyama T, Wakui K, Fukushima Y, Miyajima H, Yamaguchi S, et al. Genomic and mutational analysis of the mitochondrial trifunctional protein beta-subunit (HADHB) gene in patients with trifunctional protein deficiency. Hum Mol Genet. 1997;6:1215-24 pubmed
    ..Patient 1 was a compound heterozygote, while patient 2 was a homozygote of a G1331A transition. ..
  23. Tateno T, Ichinose A. Expression of plasminogen-related gene B varies among normal tissues and increases in cancer tissues. FEBS Lett. 1999;445:31-5 pubmed
    ..Furthermore, increased PRGB expression was observed in several fresh samples of cancer tissue obtained from cancer patients when compared with surrounding normal tissues. ..
  24. Shimokawa N, Jingu H, Okada J, Miura M. Molecular cloning of Rhombex-40 a transmembrane protein from the ventral medullary surface of the rat brain by differential display. Life Sci. 2000;66:2183-91 pubmed
    ..Whereas the biological function of this protein is presently unknown, its structural features and high expression in the brain suggest that Rhombex-40 may function as a novel transmembrane molecule in neural cells of the brain. ..
  25. Namekawa S, Hamada F, Sawado T, Ishii S, Nara T, Ishizaki T, et al. Dissociation of DNA polymerase alpha-primase complex during meiosis in Coprinus cinereus. Eur J Biochem. 2003;270:2137-46 pubmed
    ..These results suggest that the form of the DNA polymerase alpha-primase complex is altered during meiotic development...
  26. Kuroki J, Hosoya T, Itakura M, Hirose S, Tamechika I, Yoshimoto T, et al. Cloning, characterization, and tissue distribution of porcine SPAI, a protein with a transglutaminase substrate domain and the WAP motif. J Biol Chem. 1995;270:22428-33 pubmed
    ..Like elafin, therefore, SPAI appears to be a new type of biologically active substance with a transglutaminase substrate domain that acts as an anchoring sequence. ..
  27. Yoshimura A, Ichihara M, Kinjyo I, Moriyama M, Copeland N, Gilbert D, et al. Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. EMBO J. 1996;15:1055-63 pubmed
    ..Identification of murine OSM as a cytokine-inducible immediate early gene provides a new insight into the physiological function of this unique cytokine. ..
  28. Kawakami H, Maruyama H, Yasunami M, Ohkubo H, Hara H, Saida T, et al. Cloning and expression of a rat brain basic helix-loop-helix factor. Biochem Biophys Res Commun. 1996;221:199-204 pubmed
    ..6 kb and 1.8 kb) were also detected in the mouse embryo, and these decreased in the developmental process. These results suggest that BHF1 may play important roles in cerebellum-specific functions and development of neurons. ..
  29. Yamagata H, Bowler C. Molecular cloning and characterization of a cDNA encoding early light-inducible protein from soybean (Glycine max L.). Biosci Biotechnol Biochem. 1997;61:2143-4 pubmed
  30. Akagi R, Yasui Y, Harper P, Sassa S. A novel mutation of delta-aminolaevulinate dehydratase in a healthy child with 12% erythrocyte enzyme activity. Br J Haematol. 1999;106:931-7 pubmed
    ..This is also the first report of ALAD gene mutation in an asymptomatic subject. ..
  31. Tsuji Y, Suzuki I, Shiraiwa Y. Photosynthetic carbon assimilation in the coccolithophorid Emiliania huxleyi (Haptophyta): Evidence for the predominant operation of the c3 cycle and the contribution of {beta}-carboxylases to the active anaplerotic reaction. Plant Cell Physiol. 2009;50:318-29 pubmed publisher
    ..These results suggest that E. huxleyi possesses unique carbon assimila-tion mechanisms in which beta-carboxylation by both PYC and PEPC plays important roles in different organelles. ..
  32. Niimi M, Nakai Y, Aida Y. Nucleotide sequences and the molecular evolution of the DMA and DMB genes of the bovine major histocompatibility complex. Biochem Biophys Res Commun. 1995;217:522-8 pubmed
  33. Sato A, Noda K, Amaya Y, Nishino T. The structure of chicken liver xanthine dehydrogenase. cDNA cloning and the domain structure. J Biol Chem. 1995;270:2818-26 pubmed
    ..The absorption spectrum showed the sample was very similar to deflavo-enzyme. From these results and sequence analyses, the domain structure of the enzyme is discussed. ..
  34. Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, et al. An endothelial receptor for oxidized low-density lipoprotein. Nature. 1997;386:73-7 pubmed
    ..The cloned receptor is a membrane protein that belongs structurally to the C-type lectin family, and is expressed in vivo in vascular endothelium and vascular-rich organs. ..
  35. Nishimatsu H, Takeuchi T, Ueki T, Kajiwara T, Moriyama N, Ishida T, et al. CD95 ligand expression enhances growth of murine renal cell carcinoma in vivo. Cancer Immunol Immunother. 1999;48:56-61 pubmed
    ..However, CD95L-expressing renca cells did not form tumors in the renal subcapsule of allogeneic C3H/HeJ mice. ..
  36. Hayashi K, Nittono R, Okamoto N, Tsuji S, Hara Y, Goitsuka R, et al. The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells. Proc Natl Acad Sci U S A. 2000;97:2755-60 pubmed
  37. Yamasaki T, Kawaji K, Ono K, Bito H, Hirano T, Osumi N, et al. Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum. Development. 2001;128:3133-44 pubmed
    ..We propose that in addition to its roles during early patterning of the CNS, Pax6 is involved in a novel regulatory step of cytoskeletal organization during polarization and migration of CNS neurons. ..
  38. Ueda N, Okamoto Y, Morishita J. N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: a novel enzyme of the beta-lactamase fold family releasing anandamide and other N-acylethanolamines. Life Sci. 2005;77:1750-8 pubmed
    ..The existence of NAPE-PLD specifically hydrolyzing NAPEs to NAEs emphasizes physiological significance of NAEs including anandamide in brain and other tissues. ..
  39. Sakashita E, Sakamoto H. Characterization of RNA binding specificity of the Drosophila sex-lethal protein by in vitro ligand selection. Nucleic Acids Res. 1994;22:4082-6 pubmed
    ..These results suggest that Sxl recognizes and preferentially binds to a polyuridine stretch with a downstream AG sequence. ..
  40. Sugihara T, Kaul S, Kato J, Reddel R, Nomura H, Wadhwa R. Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. J Biol Chem. 2001;276:18649-52 pubmed
    ..The data demonstrated a novel mechanism of down-regulation of the p19ARF-p53 pathway. ..
  41. Ikemoto M, Inoue K, Akiduki S, Osugi T, Imamura T, Ishida N, et al. Identification of addicsin/GTRAP3-18 as a chronic morphine-augmented gene in amygdala. Neuroreport. 2002;13:2079-84 pubmed
    ..Up-regulation of addicsin expression by morphine may affect glutamate uptake in the amygdala, causing mice to develop morphine tolerance and dependence. ..
  42. Zhou J, Hikono H, Ohtaki M, Kubota T, Sakurai M. Cloning and characterization of cDNAs encoding two normal isoforms of bovine stem cell factor. Biochim Biophys Acta. 1994;1223:148-50 pubmed
    ..Northern blot analysis with the cDNA revealed the expression of a 5.8 kilobase bSCF RNA in fetal bovine tissues. ..
  43. Fukada T, Iida K, Kioka N, Sakai H, Komano T. Cloning of a cDNA encoding N-acetylglucosaminyltransferase I from rat liver and analysis of its expression in rat tissues. Biosci Biotechnol Biochem. 1994;58:200-1 pubmed
    ..We found that GnT-I mRNA was expressed in a tissue-specific manner and the pattern of its expression was suggested to be species-specific by comparison with the reported result in mice. ..
  44. Aikawa M, Sivam P, Kuro O M, Kimura K, Nakahara K, Takewaki S, et al. Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis. Circ Res. 1993;73:1000-12 pubmed
    ..We conclude from these results that smooth muscle MHC isoforms are important molecular markers for studying human vascular smooth muscle cell differentiation as well as the cellular mechanisms of atherosclerosis. ..
  45. Yamada S, Zhu Q, Aihara Y, Onda H, Zhang Z, Yu L, et al. Cloning of cDNA and the gene encoding human hepatocyte nuclear factor (HNF)-3 beta and mutation screening in Japanese subjects with maturity-onset diabetes of the young. Diabetologia. 2000;43:121-4 pubmed
    ..The characterization of the structure of the HNF-3 beta gene and its mapping in the framework of markers will be helpful in genetic studies of the various forms of diabetes mellitus. ..
  46. Igarashi M, Nagata A. Molecular cloning, sequencing and functional expression of porcine thyrotropin (TSH) receptor cDNA1). Clin Chem Lab Med. 2003;41:796-803 pubmed
    ..Chinese hamster ovary cells stably transfected with the cDNA could be specifically bound to bovine TSH (bTSH) and increased the intracellular cAMP level in response to bTSH and Graves' disease patients' sera stimulation. ..
  47. Yamada K, Tobimatsu T, Toraya T. Cloning, sequencing, and heterologous expression of rat methionine synthase cDNA. Biosci Biotechnol Biochem. 1998;62:2155-60 pubmed
    ..A high-level expression of catalytically active enzyme in insect cells was done by infection with a baculovirus containing the rat methionine synthase cDNA. ..
  48. Kono T, Sakai M. The analysis of expressed genes in the kidney of Japanese flounder, Paralichthys olivaceus, injected with the immunostimulant peptidoglycan. Fish Shellfish Immunol. 2001;11:357-66 pubmed publisher
    ..It is possible that expression of macrophage inflammatory protein 1-alpha results in macrophage activation as a consequence of peptidoglycan treatment...
  49. Yokoo T, Toyoshima H, Miura M, Wang Y, Iida K, Suzuki H, et al. p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus. J Biol Chem. 2003;278:52919-23 pubmed
  50. Tanaka H, Yamamoto M, Moriyama Y, Yamao M, Furukawa S, Sagisaka A, et al. A novel Rel protein and shortened isoform that differentially regulate antibacterial peptide genes in the silkworm Bombyx mori. Biochim Biophys Acta. 2005;1730:10-21 pubmed publisher
  51. Matsumoto K, Endo S, Ishikura S, Matsunaga T, Tajima K, El Kabbani O, et al. Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family. Biol Pharm Bull. 2006;29:539-42 pubmed
    ..Thus, AKR1C20 is a novel 3alpha(17beta)-HSD, which may also function as a reductase for xenobiotic alpha-dicarbonyl compounds. ..
  52. Ogawara D, Muroya T, Yamauchi K, Iwamoto T, Yagi Y, Yamashita Y, et al. Near-full-length REV3L appears to be a scarce maternal factor in Xenopus laevis eggs that changes qualitatively in early embryonic development. DNA Repair (Amst). 2010;9:90-5 pubmed publisher
    ..These observations indicate the existence of REV3L as a scarce protein, of approximately the full predicted size, whose level may impose severe constraints on the assembly of pol zeta in X. laevis. ..
  53. Takamatsu Y, Ohsako S, Nishida Y, Yamauchi T. Identification of an alternative form of the Drosophila Ca2+/calmodulin-dependent protein kinase II that is maternally derived. Biochim Biophys Acta. 1994;1220:188-92 pubmed
    ..Three splicing derivatives which lost one amino acid from the 509- and 530-amino-acid polypeptides were also found in 4 to 10 h embryos. ..
  54. Nishiyama H, Higashitsuji H, Yokoi H, Itoh K, Danno S, Matsuda T, et al. Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene. Gene. 1997;204:115-20 pubmed
    ..These results demonstrated that CIRP is a cold-shock protein in human cells. Identification of CIRP may provide a clue to the regulatory mechanisms of cold responses in human cells. ..
  55. Onda M, Inui S, Maeda K, Suzuki M, Takahashi E, Sakaguchi N. Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway. Genomics. 1997;46:373-8 pubmed
    ..The anti-human alpha 4 antibody detected a 45-kDa protein in human lymphoid cell lines. Moreover, human alpha 4 (IGBP1) gene is located at q13.1-q13.3 on chromosome X. ..
  56. Yamada J, Suga K, Furihata T, Kitahara M, Watanabe T, Hosokawa M, et al. cDNA cloning and genomic organization of peroxisome proliferator-inducible long-chain acyl-CoA hydrolase from rat liver cytosol. Biochem Biophys Res Commun. 1998;248:608-12 pubmed
    ..A putative peroxisome proliferator response element (AGGTCATGGTTCA) was identified in the 5'-flanking region, suggesting the involvement of peroxisome proliferator-activated receptors in the regulation of rLACH2 gene expression. ..
  57. Shinohara T, Harada M, Ogi K, Maruyama M, Fujii R, Tanaka H, et al. Identification of a G protein-coupled receptor specifically responsive to beta-alanine. J Biol Chem. 2004;279:23559-64 pubmed
    ..Our results suggest that TGR7 participates in the modulation of neuropathic pain. ..
  58. Ota E, Nagai H, Nagashima Y, Shiomi K. Molecular cloning of two toxic phospholipases A2 from the crown-of-thorns starfish Acanthaster planci venom. Comp Biochem Physiol B Biochem Mol Biol. 2006;143:54-60 pubmed publisher
    ..Furthermore, the phylogenetic tree made clearly demonstrated that AP-PLA2s and A. pectinifera PLA2s are distinguishable from the group IB PLA2s as well as other PLA2s, being classified into a new group...
  59. Nishii N, Takasu M, Soe O, Maeda S, Ohba Y, Inoue Murayama M, et al. Cloning, expression and investigation for polymorphisms of canine peroxisome proliferator-activated receptors. Comp Biochem Physiol B Biochem Mol Biol. 2007;147:690-7 pubmed
    ..These results suggest that PPARgamma may play an important role in adipocyte differentiation in dogs. Investigations for polymorphisms of PPARgamma revealed a silent polymorphism, C1362T, in 3 of 92 dogs. ..
  60. Kai M, Sakane F, Imai S, Wada I, Kanoh H. Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells. J Biol Chem. 1994;269:18492-8 pubmed
  61. Suzuki F, Miyamoto S, Takita M, Oshita M, Watanabe Y, Kakizuka A, et al. Cloning, functional expression and tissue distribution of rabbit alpha 1d-adrenoceptor. Biochim Biophys Acta. 1997;1323:6-11 pubmed
    ..Competitive RT/PCR assays revealed wide tissue distribution of the alpha 1d-adrenoceptor mRNA in rabbit, especially abundant in vas deferens, aorta, prostate and cerebral cortex. ..
  62. Fukusumi S, Kitada C, Takekawa S, Kizawa H, Sakamoto J, Miyamoto M, et al. Identification and characterization of a novel human cortistatin-like peptide. Biochem Biophys Res Commun. 1997;232:157-63 pubmed
    ..These results indicate that a bioactive peptide encoded by the cDNA is a human counterpart corresponding to rat CST. ..
  63. Kajii Y, Ninomiya D, Kato M, Mizuguchi M, Saji M, Katsumoto T, et al. A tyrosine kinase-like molecule is localized in the nuclear membrane of neurons: hippocampal behavior under stress. Biol Cell. 1996;88:45-54 pubmed
    ..Interestingly, Byk-like immunoreactivity was detected in microglial cells and astrocytes in the CA1 field that were activated after ischemia. Byk could be a new tool to study the neuron-glia and glia-glia interactions. ..
  64. Horiuchi H, Inoue T, Furusawa S, Matsuda H. Characterization and expression of three forms of cDNA encoding chicken platelet-derived growth factor-A chain. Gene. 2001;272:181-90 pubmed
    ..These results suggest that chicken PDGF in thrombocytes plays an important role in the vascular system and in healing damaged tissue. ..
  65. Furutani M, Arii S, Higashitsuji H, Mise M, Fukumoto M, Takano S, et al. Reduced expression of kan-1 (encoding putative bile acid-CoA-amino acid N-acyltransferase) mRNA in livers of rats after partial hepatectomy and during sepsis. Biochem J. 1995;311 ( Pt 1):203-8 pubmed
    ..In a sepsis model, hepatic expression of Kan-1/rBAT mRNA decreased at 6 and 12 h after caecal ligation and puncture. The kinetics of Kan-1/rBAT mRNA expression suggests that it may play a role in acute-phase reactions. ..
  66. Fukuda K, Kato S, Mori K, Nishi M, Takeshima H, Iwabe N, et al. cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett. 1994;343:42-6 pubmed
    ..RNA blot hybridization and in situ hybridization analysis revealed that ROR-C mRNA is expressed in discrete regions of the rat central nervous system. ..
  67. Wada Y, Sakamoto M. Isolation of the human phosphomannomutase gene (PMM1) and assignment to chromosome 22q13. Genomics. 1997;39:416-7 pubmed
  68. Shimokawa N, Miura M. Rhombex-29, a novel gene of the PLP/DM20-M6 family cloned from rat medulla oblongata by differential display. J Neurosci Res. 2000;62:1-8 pubmed
    ..These results indicate that the VMS neurons are endowed with a novel gene, rat Rhombex-29, that is sensitive to H(+). ..
  69. Sakakibara K, Sato K, Yoshino K, Oshiro N, Hirahara S, Mahbub Hasan A, et al. Molecular identification and characterization of Xenopus egg uroplakin III, an egg raft-associated transmembrane protein that is tyrosine-phosphorylated upon fertilization. J Biol Chem. 2005;280:15029-37 pubmed
    ..Thus, xUPIII represents an egg raft-associated protein that is likely involved in sperm-egg interaction as well as subsequent Src-dependent intracellular events of egg activation in Xenopus. ..
  70. Okuda M, Minehata K, Setoguchi A, Cho K, Nakamura N, Nishigaki K, et al. Cloning and chromosome mapping of the feline genes p21WAF1 and p27Kip1. Gene. 1997;198:141-7 pubmed
    ..RT-PCR/SSCP (single strand conformation polymorphism) analysis of p27Kip1 cDNA did not uncover any amino acid substitutions in the 10 feline leukemia and lymphoma cases that were examined. ..
  71. Hata S, Izui K, Kouchi H. Expression of a soybean nodule-enhanced phosphoenolpyruvate carboxylase gene that shows striking similarity to another gene for a house-keeping isoform. Plant J. 1998;13:267-73 pubmed
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