Experts and Doctors on cercopithecus aethiops in United States

Summary

Locale: United States
Topic: cercopithecus aethiops

Top Publications

  1. Enyedi A, Verma A, Filoteo A, Penniston J. A highly active 120-kDa truncated mutant of the plasma membrane Ca2+ pump. J Biol Chem. 1993;268:10621-6 pubmed
  2. Visalli R, Brandt C. Mutation of the herpes simplex virus 1 KOS UL45 gene reveals dose dependent effects on central nervous system growth. Arch Virol. 2002;147:519-32 pubmed
    ..We propose that the UL45 gene may play an important role under the conditions of a naturally acquired infection. ..
  3. Murinda S, Rashid K, Roberts R. In vitro assessment of the cytotoxicity of nisin, pediocin, and selected colicins on simian virus 40-transfected human colon and Vero monkey kidney cells with trypan blue staining viability assays. J Food Prot. 2003;66:847-53 pubmed
    ..Col E1, Col E3, Col E7, and Col K demonstrated little toxicity at the activities tested, indicating that they are safe and thus have potential for use as food biopreservatives...
  4. Rhee D, Marcelino J, Al Mayouf S, Schelling D, Bartels C, Cui Y, et al. Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing. J Biol Chem. 2005;280:31325-32 pubmed
    ..This suggests that formation of an intrachain disulfide bond is required for SPC-mediated cleavage and that SPC-mediated cleavage is essential to protein function. ..
  5. Kong B, Foster L, Foster D. Species-specific deletion of the viral attachment glycoprotein of avian metapneumovirus. Virus Res. 2008;132:114-21 pubmed publisher
    ..The lack of viral gene deletions suggests that avian cell propagated AMPV will provide a better alternative host for live recombinant vaccine development based on a reverse genetics system...
  6. McDoom I, Ma X, Kirabo A, Lee K, Ostrov D, Sayeski P. Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation. Biochemistry. 2008;47:8326-34 pubmed publisher
  7. Koszewski N, Herberth J, Malluche H. Retinoic acid receptor gamma 2 interactions with vitamin D response elements. J Steroid Biochem Mol Biol. 2010;120:200-7 pubmed publisher
  8. Horikami S, Smallwood S, Moyer S. The Sendai virus V protein interacts with the NP protein to regulate viral genome RNA replication. Virology. 1996;222:383-90 pubmed publisher
    ..We propose that the specific inhibition of genome replication by V and W proteins occurs through interference with either the formation or the use of the NPo-P encapsidation substrate...
  9. Janovick J, Knollman P, Brothers S, Ayala Yáñez R, Aziz A, Conn P. Regulation of G protein-coupled receptor trafficking by inefficient plasma membrane expression: molecular basis of an evolved strategy. J Biol Chem. 2006;281:8417-25 pubmed

More Information

Publications512 found, 100 shown here

  1. Kim D, Martinez Sobrido L, Choi C, Petroff N, Garcia Sastre A, Niewiesk S, et al. Induction of type I interferon secretion through recombinant Newcastle disease virus expressing measles virus hemagglutinin stimulates antibody secretion in the presence of maternal antibodies. J Virol. 2011;85:200-7 pubmed publisher
    ..These data indicate that MV-specific B cells are being generated after immunization in the presence of maternal antibodies and that the provision of alpha interferon as an additional signal leads to antibody secretion. ..
  2. Iyer J, Afanasiev O, McClurkan C, Paulson K, Nagase K, Jing L, et al. Merkel cell polyomavirus-specific CD8? and CD4? T-cell responses identified in Merkel cell carcinomas and blood. Clin Cancer Res. 2011;17:6671-80 pubmed publisher
    ..We sought to characterize T-cell responses directed against viral proteins that drive this cancer as a step toward immunotherapy...
  3. Chen B, Liang G, Whelan J, Hai T. ATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoforms. J Biol Chem. 1994;269:15819-26 pubmed
    ..It is possible that ATF3 delta Zip is a physiologically important regulator and that it, together with ATF3, regulates the expression of specific target genes. ..
  4. Sun P, Enslen H, Myung P, Maurer R. Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev. 1994;8:2527-39 pubmed
    ..In particular, changes in intracellular Ca2+ have the potential to either inhibit or augment the ability of cAMP to stimulate transcription, depending on the presence of specific forms of Ca2+/calmodulin-dependent protein kinases. ..
  5. Johnson M, Kuo Y, Westaway S, Parker S, Ching K, Gitschier J, et al. Mitochondrial localization of human PANK2 and hypotheses of secondary iron accumulation in pantothenate kinase-associated neurodegeneration. Ann N Y Acad Sci. 2004;1012:282-98 pubmed
    ..This common variant may cause mitochondrial dysfunction and impart susceptibility to late-onset neurodegenerative disorders with brain iron accumulation, including Parkinson's disease. ..
  6. Aubert M, Krantz E, Jerome K. Herpes simplex virus genes Us3, Us5, and Us12 differentially regulate cytotoxic T lymphocyte-induced cytotoxicity. Viral Immunol. 2006;19:391-408 pubmed publisher
    ..Taken together, these results suggest that HSV evasion of cellular immunity is multifacterial and complex, and relies on the partially redundant activities of various individual HSV proteins...
  7. Valdivia C, Medeiros Domingo A, Ye B, Shen W, Algiers T, Ackerman M, et al. Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation. Cardiovasc Res. 2010;86:392-400 pubmed publisher
    ..This study provides molecular and cellular evidence implicating mutations in Navbeta3 as a cause of IVF. ..
  8. Hu G, Wang X, Saunders D, Henderson M, Russell A, Herring B, et al. Modulation of myocardin function by the ubiquitin E3 ligase UBR5. J Biol Chem. 2010;285:11800-9 pubmed publisher
    ..This study reveals an unexpected role for the ubiquitin E3 ligase UBR5 as an activator of smooth muscle differentiation through its ability to stabilize myocardin protein...
  9. Yeh H, Yates M, Mulchandani A, Chen W. Molecular beacon-quantum dot-Au nanoparticle hybrid nanoprobes for visualizing virus replication in living cells. Chem Commun (Camb). 2010;46:3914-6 pubmed publisher
  10. Lim P, Keating J, Hoover S, Striker R, Bernard K. A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice. PLoS ONE. 2011;6:e26697 pubmed publisher
  11. Hebbring S, Chai Y, Ji Y, Abo R, Jenkins G, Fridley B, et al. Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization. J Neurochem. 2012;120:881-90 pubmed publisher
    ..In addition, we obtained preliminary indications that these genes may be co-regulated with other Folate and Methionine Cycle genes. ..
  12. Fay J, Farrens D. A key agonist-induced conformational change in the cannabinoid receptor CB1 is blocked by the allosteric ligand Org 27569. J Biol Chem. 2012;287:33873-82 pubmed
    ..The underlying mechanism behind this behavior is that simultaneous binding of Org 27569 produces a unique agonist-bound conformation, one that may resemble an intermediate structure formed on the pathway to full receptor activation. ..
  13. Anderson E, Thomas L, Hayflick J, Thomas G. Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant. J Biol Chem. 1993;268:24887-91 pubmed
    ..The potential use of alpha 1-PDX in manipulating the activation of proproteins in a tissue- and time-specific manner is discussed. ..
  14. Gray J, Burns K, Leas T, Perdew G, Vanden Heuvel J. Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C. Biochemistry. 2005;44:10313-21 pubmed
    ..Together, these studies demonstrate a direct role for PKC in the regulation of PPARalpha, and suggest several PKCs can regulate PPARalpha activity through multiple phosphorylation sites. ..
  15. Xu H, Fu Y, Tian W, Cohen D. Glycosylation of the osmoresponsive transient receptor potential channel TRPV4 on Asn-651 influences membrane trafficking. Am J Physiol Renal Physiol. 2006;290:F1103-9 pubmed
    ..These data point to a potentially conserved structural and functional feature influencing membrane trafficking across diverse members of the voltage-gated-like ion channel superfamily. ..
  16. Greenberg M, Sun M, Zhang R, Febbraio M, Silverstein R, Hazen S. Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells. J Exp Med. 2006;203:2613-25 pubmed
    ..Collectively, these results identify oxPS-CD36 interactions on macrophages as potential participants in a broad range of physiologic processes where macrophage-mediated engulfment of apoptotic cells is involved. ..
  17. Fuller D, Shipley T, Allen T, Fuller J, Wu M, Horton H, et al. Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques. Virology. 2007;364:245-55 pubmed
    ..These data demonstrate that immunization with hybrid HBcAg-epitope DNA vaccines is an effective strategy to increase the magnitude and breadth of HIV-specific CTL responses. ..
  18. Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, et al. Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog. 2010;6:e1001121 pubmed publisher
    ..These findings provide new insights into the lifecycle of Ebolavirus and may aid in the development of therapeutics for Ebolavirus infection. ..
  19. Islam M, Jimenez T, Pelham C, Rodova M, Puri S, Magenheimer B, et al. MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor protein. J Biol Chem. 2010;285:38818-31 pubmed publisher
    ..An Mekk1-p53 interaction at the PKD1 promoter suggests a new mechanism by which abnormally elevated stress-pathway stimuli might directly down-regulate the PKD1 gene, possibly causing haploinsufficiency and cyst formation. ..
  20. Guo Y, Dolinko A, Chinyengetere F, STANTON B, Bomberger J, Demidenko E, et al. Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RAR? and inhibits the growth of acute promyelocytic leukemia. Cancer Res. 2010;70:9875-85 pubmed publisher
    ..In contrast, elevation of UBP43 expression stabilized PML/RAR? protein and inhibited apoptosis. Taken together, our findings define the ubiquitin protease UBP43 as a novel candidate drug target for APL treatment. ..
  21. Brown J, Ortiz G, Angel T, Jacobs J, Gritsenko M, Chan E, et al. Morphine produces immunosuppressive effects in nonhuman primates at the proteomic and cellular levels. Mol Cell Proteomics. 2012;11:605-18 pubmed publisher
  22. Santa Maria F, Laughhunn A, Lanteri M, Aubry M, Musso D, Stassinopoulos A. Inactivation of Zika virus in platelet components using amotosalen and ultraviolet A illumination. Transfusion. 2017;57:2016-2025 pubmed publisher
  23. Craft W, Dutch R. Sequence motif upstream of the Hendra virus fusion protein cleavage site is not sufficient to promote efficient proteolytic processing. Virology. 2005;341:130-40 pubmed
    ..These data indicate that the upstream region can play a role in protease recognition, but is neither absolutely required nor sufficient for efficient processing of the HeV F protein. ..
  24. Southern T, Jolly C, Lester M, Hayman J. EnP1, a microsporidian spore wall protein that enables spores to adhere to and infect host cells in vitro. Eukaryot Cell. 2007;6:1354-62 pubmed
  25. Sun W, Hu K. Role for SUR2A in coupling cardiac K(ATP) channels to caveolin-3. Cell Physiol Biochem. 2010;25:409-18 pubmed publisher
    ..We concluded that SUR2A is important for coupling cardiac K(ATP) channels to caveolin-3, possibly through the caveolin-3 scaffolding domain. ..
  26. Wang Y, Langer N, Shaw G, Yang G, Li L, Kaplan J, et al. Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria. Exp Hematol. 2011;39:784-94 pubmed publisher
    ..Abnormal MFRN1 expression can contribute to erythropoietic protoporphyria phenotype in some patients, probably by causing a reduction in FECH activity. ..
  27. Chang A, Hackett B, Winter C, Buchholz U, Dutch R. Potential electrostatic interactions in multiple regions affect human metapneumovirus F-mediated membrane fusion. J Virol. 2012;86:9843-53 pubmed publisher
    ..As a whole, these studies implicate charged residues and potential electrostatic interactions in function, pH sensing, and overall stability of HMPV F...
  28. He X, Patfield S, Hnasko R, Rasooly R, Mandrell R. A polyclonal antibody based immunoassay detects seven subtypes of Shiga toxin 2 produced by Escherichia coli in human and environmental samples. PLoS ONE. 2013;8:e76368 pubmed publisher
    ..The results of epitope mapping from this study will be useful for further development of a peptide-based antibody and vaccine. ..
  29. von Messling V, Springfeld C, Devaux P, Cattaneo R. A ferret model of canine distemper virus virulence and immunosuppression. J Virol. 2003;77:12579-91 pubmed
    ..Thus, virulence-inducing mutations have accumulated throughout the genome. ..
  30. Prasch A, Tanguay R, Mehta V, Heideman W, Peterson R. Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1. Mol Pharmacol. 2006;69:776-87 pubmed
  31. Crimmins S, Jin Y, Wheeler C, Huffman A, Chapman C, Dobrunz L, et al. Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14. J Neurosci. 2006;26:11423-31 pubmed
  32. Gottlieb P, Folgering J, Maroto R, Raso A, Wood T, Kurosky A, et al. Revisiting TRPC1 and TRPC6 mechanosensitivity. Pflugers Arch. 2008;455:1097-103 pubmed
  33. Hata K, Polo Parada L, Landmesser L. Selective targeting of different neural cell adhesion molecule isoforms during motoneuron myotube synapse formation in culture and the switch from an immature to mature form of synaptic vesicle cycling. J Neurosci. 2007;27:14481-93 pubmed
    ..These observations indicate that postsynaptic NCAM is required for the synaptic targeting of presynaptic 140 NCAM but that the localization of presynaptic 180 NCAM occurs via a different mechanism. ..
  34. Hoeppner L, Secreto F, Razidlo D, Whitney T, Westendorf J. Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass. J Biol Chem. 2011;286:10950-9 pubmed publisher
    ..Together, our data indicate that Lef1?N binds ?-catenin, stimulates Lef/Tcf reporter activity, and promotes terminal osteoblast differentiation. ..
  35. Giorda K, Raghava S, Zhang M, Hebert D. The viroporin activity of the minor structural proteins VP2 and VP3 is required for SV40 propagation. J Biol Chem. 2013;288:2510-20 pubmed publisher
    ..This comprehensive approach revealed that the viroporin activity of VP2 and VP3 was inhibited by targeted disruptions of individual hydrophobic domains and the loss of membrane disruption activity impaired viral infection. ..
  36. Xu P, Chen Z, Phan S, Pickar A, He B. Immunogenicity of novel mumps vaccine candidates generated by genetic modification. J Virol. 2014;88:2600-10 pubmed publisher
    ..Analysis of rMuV?SH?V indicated that it was stable in tissue culture cell lines. Importantly, rMuV?SH?V was immunogenic in mice, indicating that it is a promising candidate for mumps vaccine development. ..
  37. Pocock G, Becker J, Swanson C, Ahlquist P, Sherer N. HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors. PLoS Pathog. 2016;12:e1005565 pubmed publisher
    ..Combined, these results reveal striking, unexpected features of retroviral gRNA nucleocytoplasmic transport and demonstrate roles for mRNA export elements that extend beyond nuclear pores to impact gRNA distribution in the cytoplasm. ..
  38. Kim S, Yamazaki M, Zella L, Shevde N, Pike J. Activation of receptor activator of NF-kappaB ligand gene expression by 1,25-dihydroxyvitamin D3 is mediated through multiple long-range enhancers. Mol Cell Biol. 2006;26:6469-86 pubmed
  39. Ramaker J, Swanson T, Copenhaver P. Amyloid precursor proteins interact with the heterotrimeric G protein Go in the control of neuronal migration. J Neurosci. 2013;33:10165-81 pubmed publisher
    ..These results support the model that APP and its orthologs regulate conserved aspects of neuronal migration and outgrowth in the nervous system by functioning as unconventional Go?-coupled receptors. ..
  40. Kisiela D, Aulik N, Atapattu D, Czuprynski C. N-terminal region of Mannheimia haemolytica leukotoxin serves as a mitochondrial targeting signal in mammalian cells. Cell Microbiol. 2010;12:976-87 pubmed publisher
    ..coli. These findings provide a new evidence for the importance of the N-terminal region in addressing certain RTX toxins to mitochondria. ..
  41. Tomlinson S, Ueda E, Maruniak J, Garcia Canedo A, Bjes E, Esser A. The expression of hemolytically active human complement protein C9 in mammalian, insect, and yeast cells. Protein Expr Purif. 1993;4:141-8 pubmed
    ..Thus, for future studies on the structure and function of C9 where the production of large quantities of mutant protein would be desirable, the baculovirus-insect cell expression system appears to offer considerable advantages. ..
  42. Watanabe S, Watanabe T, Noda T, Takada A, Feldmann H, Jasenosky L, et al. Production of novel ebola virus-like particles from cDNAs: an alternative to ebola virus generation by reverse genetics. J Virol. 2004;78:999-1005 pubmed
    ..Thus, this system allows us to study Ebola virus entry, replication, and assembly without biosafety level 4 containment. Furthermore, it may be useful in vaccine production against this highly pathogenic agent...
  43. Deka S, Vanover J, Sun J, Kintner J, Whittimore J, Schoborg R. An early event in the herpes simplex virus type-2 replication cycle is sufficient to induce Chlamydia trachomatis persistence. Cell Microbiol. 2007;9:725-37 pubmed
    ..These data demonstrate that productive viral replication is not required for the induction of chlamydial persistence and suggest that HSV attachment and entry can provide the necessary stimulus to alter C. trachomatis development. ..
  44. Turner P, Dilling B, Prins C, Cresawn S, Moyer R, Condit R. Vaccinia virus temperature-sensitive mutants in the A28 gene produce non-infectious virions that bind to cells but are defective in entry. Virology. 2007;366:62-72 pubmed
    ..The Cts9 phenotype suggests that the A28 protein is involved in both virus entry and cell-cell fusion, and supports the linkage between the two processes. ..
  45. Shatzer A, Kato S, Condit R. Phenotypic analysis of a temperature sensitive mutant in the large subunit of the vaccinia virus mRNA capping enzyme. Virology. 2008;375:236-52 pubmed publisher
  46. Becker M, Obraztsova M, Kern E, Quenelle D, Keith K, Prichard M, et al. Isolation and characterization of cidofovir resistant vaccinia viruses. Virol J. 2008;5:58 pubmed publisher
    ..One mode of action for CDV has been demonstrated to be the inhibition of the viral DNA polymerase...
  47. Allen C, Paraskevakou G, Iankov I, Giannini C, Sarkaria J, Schroeder M, et al. Interleukin-13 displaying retargeted oncolytic measles virus strains have significant activity against gliomas with improved specificity. Mol Ther. 2008;16:1556-64 pubmed publisher
    ..Strains of measles virus retargeted against the glioma-specific IL-13Ralpha2 receptor have comparable therapeutic efficacy, and improved specificity as compared with the unmodified measles virus strain MV-GFP in vitro and in vivo. ..
  48. Emond M, Biswas S, Jontes J. Protocadherin-19 is essential for early steps in brain morphogenesis. Dev Biol. 2009;334:72-83 pubmed publisher
    ..These results provide the first functional data for protocadherin-19, demonstrating an essential role in early brain development. ..
  49. Sodora D, Allan J, Apetrei C, Brenchley J, Douek D, Else J, et al. Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat Med. 2009;15:861-5 pubmed publisher
  50. Szpara M, Parsons L, Enquist L. Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations. J Virol. 2010;84:5303-13 pubmed publisher
    ..These data increase our knowledge of sequence variation in large DNA viruses and demonstrate the potential of deep sequencing to yield insight into DNA genome evolution and the variation among different pathogen isolates. ..
  51. Chu U, Ramachandran S, Hajipour A, Ruoho A. Photoaffinity labeling of the sigma-1 receptor with N-[3-(4-nitrophenyl)propyl]-N-dodecylamine: evidence of receptor dimers. Biochemistry. 2013;52:859-68 pubmed publisher
    ..The proposed binding and reactivity of 4-NPPC12 evoke a ligand binding model for the sigma-1 receptor that likely involves a receptor dimer and/or oligomer. ..
  52. Miest T, Frenzke M, Cattaneo R. Measles virus entry through the signaling lymphocyte activation molecule governs efficacy of mantle cell lymphoma radiovirotherapy. Mol Ther. 2013;21:2019-31 pubmed publisher
  53. Liu Y, Russell S, Ayala Breton C, Russell S, Peng K. Ablation of nectin4 binding compromises CD46 usage by a hybrid vesicular stomatitis virus/measles virus. J Virol. 2014;88:2195-204 pubmed publisher
    ..Thus, our results support continued preclinical development of VSVFH without ablation of nectin4 binding. ..
  54. Navaratnarajah C, Kumar S, Generous A, Apte Sengupta S, Mateo M, Cattaneo R. The measles virus hemagglutinin stalk: structures and functions of the central fusion activation and membrane-proximal segments. J Virol. 2014;88:6158-67 pubmed publisher
  55. Dezzutti C, Lazo A, Yee J, Blakeslee J, Mathes L, Brown B, et al. Detection of simian T-lymphotropic virus type I using the polymerase chain reaction. Int J Cancer. 1992;50:805-10 pubmed
    ..Additionally, our data suggest that the tax and pol gene regions are conserved between HTLV-I and STLV-I strains found among these diverse species of non-human primates...
  56. Anand B, Hill J, Dey S, Maruyama K, Bhattacharjee P, Myles M, et al. In vivo antiviral efficacy of a dipeptide acyclovir prodrug, val-val-acyclovir, against HSV-1 epithelial and stromal keratitis in the rabbit eye model. Invest Ophthalmol Vis Sci. 2003;44:2529-34 pubmed
    ..The less cytotoxic and highly water-soluble prodrug VVACV, which showed excellent in vivo activity against HSV-1 in rabbit epithelial and stromal keratitis, is a promising drug candidate for treatment of ocular HSV infections. ..
  57. Schepp Berglind J, Luo M, Wang D, Wicker J, Raja N, Hoel B, et al. Complex adenovirus-mediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses. Clin Vaccine Immunol. 2007;14:1117-26 pubmed
  58. Sun B, Boyanovsky B, Connelly M, Shridas P, van der Westhuyzen D, Webb N. Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI. J Lipid Res. 2007;48:2560-70 pubmed
  59. Barhoover M, Orban T, Beck D, Bukys M, Kalafatis M. Contribution of amino acid region 334-335 from factor Va heavy chain to the catalytic efficiency of prothrombinase. Biochemistry. 2008;47:6840-50 pubmed publisher
    ..The data demonstrate that amino acid region 334-335 is required for the rearrangement of enzyme and substrate necessary for efficient catalysis of prothrombin by prothrombinase. ..
  60. Freamat M, Sower S. A sea lamprey glycoprotein hormone receptor similar with gnathostome thyrotropin hormone receptor. J Mol Endocrinol. 2008;41:219-28 pubmed publisher
    ..Overall, the presence and characteristics of the lamprey glycoprotein hormone receptors suggest existence of a primitive functionally overlapping glycoprotein hormone/glycoprotein hormone receptor system in this animal. ..
  61. Conklin M, Ada Nguema A, Parsons M, Riching K, Keely P. R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis. BMC Cell Biol. 2010;11:14 pubmed publisher
  62. Ruan C, So S, Ruan K. Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: mechanisms of COX-2 inhibitor risk to heart disease. Life Sci. 2011;88:24-30 pubmed publisher
  63. Kuksin D, Norkin L. Disassembly of simian virus 40 during passage through the endoplasmic reticulum and in the cytoplasm. J Virol. 2012;86:1555-62 pubmed publisher
    ..First, a partial disassembly of the particles occurs in the ER, which exposes internal capsid proteins VP2 and VP3. Then, in the cytoplasm, disassembly progresses further to also make the genomic DNA accessible to immune detection. ..
  64. Markert J, Cody J, Parker J, Coleman J, Price K, Kern E, et al. Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12. J Virol. 2012;86:5304-13 pubmed publisher
    ..nancymae lymphocytes in vitro. We conclude that the safety and preclinical efficacy of M002 warrants the advancement of a ??(1)34.5 virus expressing IL-12 to phase I clinical trials for patients with recurrent malignant glioma. ..
  65. John S, Russell L, Chin S, Luo W, Oshima R, Garrett Sinha L. Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation. Mol Cell Biol. 2014;34:522-32 pubmed publisher
    ..Differences between the N termini of Ets1 and Ets2, rather than differences in the DNA binding domains, determine whether the proteins are capable of blocking ASC formation or not. ..
  66. Phan S, Adam C, Chen Z, Citron M, Liang X, Espeseth A, et al. Genetic Stability of Parainfluenza Virus 5-Vectored Human Respiratory Syncytial Virus Vaccine Candidates after In Vitro and In Vivo Passage. J Virol. 2017;91: pubmed publisher
    ..Interestingly, the function of the inserted gene may have an impact on PIV5 genome stability. ..
  67. Ellison T, Dowd D, MacDonald P. Calmodulin-dependent kinase IV stimulates vitamin D receptor-mediated transcription. Mol Endocrinol. 2005;19:2309-19 pubmed
  68. Lin C, Lin Y, Yan F, Casey J, Kochhar M, Pratt E, et al. Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy. Diabetes. 2006;55:1738-46 pubmed
    ..Interestingly, sulfonylureas significantly increase surface expression of certain PNDM mutants, suggesting that the efficacy of sulfonylurea therapy may be compromised by the effect of these drugs on channel expression. ..
  69. Chang K. Role of cholesterol pathways in norovirus replication. J Virol. 2009;83:8587-95 pubmed publisher
    ..I conclude that the cholesterol pathways such as LDLR expression and ACAT activity may be crucial in the replication of noroviruses in cells, which may provide potential therapeutic targets for viral infection. ..
  70. Pandrea I, Parrish N, Raehtz K, Gaufin T, Barbian H, Ma D, et al. Mucosal simian immunodeficiency virus transmission in African green monkeys: susceptibility to infection is proportional to target cell availability at mucosal sites. J Virol. 2012;86:4158-68 pubmed publisher
  71. Bushman J, Zhou Q, Shyng S. A Kir6.2 pore mutation causes inactivation of ATP-sensitive potassium channels by disrupting PIP2-dependent gating. PLoS ONE. 2013;8:e63733 pubmed publisher
    ..The G156P mutation provides mechanistic insight into the structural and functional interactions between the pore and cytoplasmic domains of Kir6.2 during gating. ..
  72. Marin M, Rose K, Kozak S, Kabat D. HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. Nat Med. 2003;9:1398-403 pubmed
    ..These results provide promising approaches for drug discovery. ..
  73. Rhodes K, Carroll K, Sung M, Doliveira L, Monaghan M, Burke S, et al. KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain. J Neurosci. 2004;24:7903-15 pubmed
  74. Bose M, Whittal R, Miller W, Bose H. Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein. J Biol Chem. 2008;283:8837-45 pubmed publisher
    ..VDAC1 and phosphate carrier protein are the first OMM proteins shown to contact StAR. ..
  75. Wurth M, Schowalter R, Smith E, Moncman C, Dutch R, McCann R. The actin cytoskeleton inhibits pore expansion during PIV5 fusion protein-promoted cell-cell fusion. Virology. 2010;404:117-26 pubmed publisher
    ..These data suggest that the cortical actin cytoskeleton is an important regulator of fusion pore enlargement, an energetically costly stage of viral fusion protein-mediated membrane merger. ..
  76. Salabei J, Li X, Petrash J, Bhatnagar A, Barski O. Functional expression of novel human and murine AKR1B genes. Chem Biol Interact. 2011;191:177-84 pubmed publisher
    ..From these observations we conclude that the predicted AKR1B15 and 1b16 genes are expressed in several murine and human tissues. Further studies are required to elucidate their physiological roles. ..
  77. George R, McVicker G, Diederich R, Ng S, Mackenzie A, Swanson W, et al. Trans genomic capture and sequencing of primate exomes reveals new targets of positive selection. Genome Res. 2011;21:1686-94 pubmed publisher
    ..These results demonstrate the power of second-generation sequencing in comparative genomics and greatly expand the repertoire of available primate coding sequences. ..
  78. Wroblewski J, Jahangiri A, Ji A, de Beer F, van der Westhuyzen D, Webb N. Nascent HDL formation by hepatocytes is reduced by the concerted action of serum amyloid A and endothelial lipase. J Lipid Res. 2011;52:2255-61 pubmed publisher
    ..Our findings suggest that a reduction in nascent HDL formation may be partly responsible for reduced HDL-C during inflammation when both EL and SAA are known to be upregulated. ..
  79. Ihnatovych I, Migocka Patrzalek M, Dukh M, Hofmann W. Identification and characterization of a novel myosin Ic isoform that localizes to the nucleus. Cytoskeleton (Hoboken). 2012;69:555-65 pubmed publisher
  80. Jackson B, Brewster C, Paulson S. La Crosse virus infection alters blood feeding behavior in Aedes triseriatus and Aedes albopictus (Diptera: Culicidae). J Med Entomol. 2012;49:1424-9 pubmed
    ..albopictus. Reduction in bloodmeal size followed by an increased avidity for refeeding may lead to enhanced horizontal transmission of the LACV by its principal vector, Ae. triseriatus. ..
  81. Pandya K, Townes T. Basic residues within the Kruppel zinc finger DNA binding domains are the critical nuclear localization determinants of EKLF/KLF-1. J Biol Chem. 2002;277:16304-12 pubmed
    ..The basic residues of all mammalian Kruppel zinc fingers are highly conserved; therefore we propose that these basic residues are a common NLS shared by all Kruppel family members. ..
  82. Carbone M, Burck C, Rdzanek M, Rudzinski J, Cutrone R, Bocchetta M. Different susceptibility of human mesothelial cells to polyomavirus infection and malignant transformation. Cancer Res. 2003;63:6125-9 pubmed
    ..SV40 did not lyse mesothelial cells and caused a high rate of transformation. These findings provide a rationale for the observation that SV40 is found in mesothelioma, rather than the ubiquitous human JCV and BKV. ..
  83. Huan J, Streicher J, Bleyle L, Koop D. Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells. Toxicol Appl Pharmacol. 2004;199:332-43 pubmed
    ..Furthermore, the addition of the hsp90 inhibitors geldanamycin, herbimycin, and radicicol had no effect on the turnover of CYP2E1, differentiating the degradation of CYP2E1 from other substrates for proteasome-dependent degradation. ..
  84. Zhao F, Miller P, Wall E, Zheng Y, Dong B, Neville M, et al. Bovine glucose transporter GLUT8: cloning, expression, and developmental regulation in mammary gland. Biochim Biophys Acta. 2004;1680:103-13 pubmed
    ..These results suggest that GLUT8 expression may be regulated by lactogenic hormones and that GLUT8 may play a role in glucose uptake in the lactating mammary gland. ..
  85. Van Hoeven N, Miller A. Improved enzootic nasal tumor virus pseudotype packaging cell lines reveal virus entry requirements in addition to the primary receptor Hyal2. J Virol. 2005;79:87-94 pubmed
    ..These results indicate the possibility of a coreceptor requirement for these viruses. ..
  86. Kalita K, Kharebava G, Zheng J, Hetman M. Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity. J Neurosci. 2006;26:10020-32 pubmed
    ..In addition, MKL1 appears as a novel mediator of the signaling between ERK1/2 and SRF. Moreover, MKL1 is a likely regulator of SRF-driven transcription programs that underlie neuronal plasticity. ..
  87. John S, Clements J, Russell L, Garrett Sinha L. Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1. J Biol Chem. 2008;283:951-62 pubmed
    ..These results reveal a previously unknown mechanism for the control of Blimp-1 activity by Ets-1 and suggest that expression of Ets-1 must be down-regulated before plasmacytic differentiation can occur. ..
  88. Kuninger D, Kuns Hashimoto R, Nili M, Rotwein P. Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin. BMC Biochem. 2008;9:9 pubmed publisher
    ..Our results define a role for PCs in the maturation of RGMc that may have implications for the physiological actions of this critical iron-regulatory protein. ..
  89. Kutz W, Wang L, Dagoneau N, Odrcic K, Cormier Daire V, Traboulsi E, et al. Functional analysis of an ADAMTS10 signal peptide mutation in Weill-Marchesani syndrome demonstrates a long-range effect on secretion of the full-length enzyme. Hum Mutat. 2008;29:1425-34 pubmed publisher
  90. Chen D, Zhang J, Li M, Rayburn E, Wang H, Zhang R. RYBP stabilizes p53 by modulating MDM2. EMBO Rep. 2009;10:166-72 pubmed publisher
    ..Expression of RYBP is decreased in human cancer tissues compared with adjacent normal tissues. These results show that RYBP is a new regulator of the MDM2-p53 loop and that it has tumour suppressor activity. ..
  91. Matsuda D, Sato H, Maquat L. Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells. Methods Enzymol. 2008;449:177-201 pubmed publisher
    ..This chapter provides guidelines and protocols for how to define NMD targets using cultured mammalian cells. ..
  92. Hill K, Roemer S, Jones D, Churchill M, Edwards D. A progesterone receptor co-activator (JDP2) mediates activity through interaction with residues in the carboxyl-terminal extension of the DNA binding domain. J Biol Chem. 2009;284:24415-24 pubmed publisher
    ..These studies provide insights into the role and functional importance of the CTE for co-activator interactions. ..