Experts and Doctors on cell size in Austria


Locale: Austria
Topic: cell size

Top Publications

  1. Kaitna S, Schnabel H, Schnabel R, Hyman A, Glotzer M. A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo. J Cell Sci. 2002;115:2293-302 pubmed
    ..These data indicate that the deubiquitination of certain substrates by CYK-3 is crucial for cellular osmoregulation. Defects in osmoregulation appear to indirectly affect actin-dependent processes. ..
  2. Chiocchetti A, Zhou J, Zhu H, Karl T, Haubenreisser O, Rinnerthaler M, et al. Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span. Exp Gerontol. 2007;42:275-86 pubmed
    ..Thus, reduction of gene dosage of RP genes belonging to both the 60S and the 40S subunit affect lifespan, possibly altering the aging process by modulation of translation. ..
  3. Oehler R, Zellner M, Hefel B, Weingartmann G, Spittler A, Struse H, et al. Influence of heat shock on cell volume regulation: protection from hypertonic challenge in a human monocyte cell line. FASEB J. 1998;12:553-60 pubmed
    ..Our results indicate that heat shock of U937 cells activates a hitherto unknown cytoprotective effect that may help cells to overcome hypertonic challenge. ..
  4. Ruscheweyh R, Goralczyk A, Wunderbaldinger G, Schober A, Sandkuhler J. Possible sources and sites of action of the nitric oxide involved in synaptic plasticity at spinal lamina I projection neurons. Neuroscience. 2006;141:977-88 pubmed
    ..Lamina I spino-parabrachial neurons were stained for comparison and yielded similar results. ..
  5. Scandella E, Nagl U, Oehl B, Bergmann F, Gschwentner M, Furst J, et al. The promoter for constitutive expression of the human ICln gene CLNS1A. J Biol Chem. 2000;275:15613-20 pubmed
    ..In addition to the starting sites, upstream sequence elements are mandatory for an efficient transcription of the ICln gene (CLNS1A). These new nucleotide elements were defined by site-directed mutagenesis. ..
  6. Hengstschlager M. Tuberous sclerosis complex genes: from flies to human genetics. Arch Dermatol Res. 2001;293:383-6 pubmed
  7. Rosner M, Hofer K, Kubista M, Hengstschlager M. Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38. Oncogene. 2003;22:4786-98 pubmed
    ..These data provide new insights into mammalian cell size regulation and allow a better understanding of the function of human TSC genes. ..
  8. Böhm E, Sturm G, Weiglhofer I, Sandig H, Shichijo M, McNamee A, et al. 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. J Biol Chem. 2004;279:7663-70 pubmed
    ..Given its production in the allergic lung, antagonism of the 11-dehydro-TXB(2)/CRTH2axis may be of therapeutic relevance. ..
  9. Chang Rodriguez S, Ecker R, Stingl G, Elbe Bürger A. Autocrine IL-10 partially prevents differentiation of neonatal dendritic epidermal leukocytes into Langerhans cells. J Leukoc Biol. 2004;76:657-66 pubmed
    ..We conclude that IL-10 is one of the factors preventing maturation and differentiation of DEL into immunocompetent LC in intrauterine life and is at least partly responsible for the poor immune responsiveness of neonates. ..

More Information


  1. Shim K, Rosner M, Freilinger A, Lubec G, Hengstschlager M. Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells. Exp Cell Res. 2006;312:2264-78 pubmed
    ..It would have negative effects on proliferation and differentiation of these cells. In differentiated neuronal cells Bach2 expression is upregulated, which could allow Bach2 to function as a gatekeeper of the differentiated status. ..
  2. Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 2006;312:734-7 pubmed
    ..These results indicate that ATGL is rate limiting in the catabolism of cellular fat depots and plays an important role in energy homeostasis. ..
  3. Bozec A, Bakiri L, Hoebertz A, Eferl R, Schilling A, Komnenovic V, et al. Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia. Nature. 2008;454:221-5 pubmed publisher
    ..Thus placenta-induced hypoxia during embryogenesis leads to the formation of giant osteoclasts in young pups. These findings offer potential targets for the treatment of syndromes associated with increased osteoclastogenesis. ..
  4. Dossena S, Gandini R, Tamma G, Vezzoli V, Nofziger C, Tamplenizza M, et al. The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume. J Biol Chem. 2011;286:40659-70 pubmed publisher
    ..Moreover, NMR and additional biochemical techniques enabled us to identify the putative ICln/HSPC038 interacting sites, thereby explaining the functional interaction of both proteins on a molecular level. ..