Genomes and Genes
Experts and Doctors on cell size in Austria
Topic: cell size
- Shim K, Rosner M, Freilinger A, Lubec G, Hengstschlager M. Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells. Exp Cell Res. 2006;312:2264-78 pubmed..It would have negative effects on proliferation and differentiation of these cells. In differentiated neuronal cells Bach2 expression is upregulated, which could allow Bach2 to function as a gatekeeper of the differentiated status. ..
- Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 2006;312:734-7 pubmed..These results indicate that ATGL is rate limiting in the catabolism of cellular fat depots and plays an important role in energy homeostasis. ..
- Bozec A, Bakiri L, Hoebertz A, Eferl R, Schilling A, Komnenovic V, et al. Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia. Nature. 2008;454:221-5 pubmed publisher..Thus placenta-induced hypoxia during embryogenesis leads to the formation of giant osteoclasts in young pups. These findings offer potential targets for the treatment of syndromes associated with increased osteoclastogenesis. ..
- Dossena S, Gandini R, Tamma G, Vezzoli V, Nofziger C, Tamplenizza M, et al. The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume. J Biol Chem. 2011;286:40659-70 pubmed publisher..Moreover, NMR and additional biochemical techniques enabled us to identify the putative ICln/HSPC038 interacting sites, thereby explaining the functional interaction of both proteins on a molecular level. ..