Experts and Doctors on cell movement in Germany

Summary

Locale: Germany
Topic: cell movement

Top Publications

  1. Deindl E, Ziegelhoffer T, Kanse S, Fernandez B, Neubauer E, Carmeliet P, et al. Receptor-independent role of the urokinase-type plasminogen activator during arteriogenesis. FASEB J. 2003;17:1174-6 pubmed
    ..We conclude that arteriogenesis is promoted by an uPA-mediated infiltration of leukocytes that is not dependent on uPAR. ..
  2. Fischer S, Draper B, Neumann C. The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation. Development. 2003;130:3515-24 pubmed
    ..We also show that fgf24 activity is necessary for the migration of tbx5-expressing cells to the fin bud, and for the activation of shh, but not hand2, expression in the posterior fin bud. ..
  3. Haase A, Bicker G. Nitric oxide and cyclic nucleotides are regulators of neuronal migration in an insect embryo. Development. 2003;130:3977-87 pubmed
    ..These findings reveal an accessible invertebrate model in which the role of the NO and cyclic nucleotide signalling in neuronal migration can be analyzed in a natural setting. ..
  4. Sadowski T, Dietrich S, Koschinsky F, Sedlacek R. Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3. Mol Biol Cell. 2003;14:4569-80 pubmed
    ..This activity might have widespread consequences for the behavior of epidermal keratinocytes. ..
  5. Curtze S, Dembo M, Miron M, Jones D. Dynamic changes in traction forces with DC electric field in osteoblast-like cells. J Cell Sci. 2004;117:2721-9 pubmed
    ..We could not correlate the initial traction changes with any change in intracellular free calcium levels measured using the fluorescent dye Fura-2 AM. ..
  6. Brakebusch C, Fassler R. beta 1 integrin function in vivo: adhesion, migration and more. Cancer Metastasis Rev. 2005;24:403-11 pubmed
  7. Tarbashevich K, Koebernick K, Pieler T. XGRIP2.1 is encoded by a vegetally localizing, maternal mRNA and functions in germ cell development and anteroposterior PGC positioning in Xenopus laevis. Dev Biol. 2007;311:554-65 pubmed
    ..1 protein fragment reduced average PGC numbers and interfered with the proper anteroposterior positioning of PGCs at tailbud stages. Thus, our results suggest that XGRIP2.1 is required for normal PGC development and migration in Xenopus. ..
  8. Boldajipour B, Mahabaleshwar H, Kardash E, Reichman Fried M, Blaser H, Minina S, et al. Control of chemokine-guided cell migration by ligand sequestration. Cell. 2008;132:463-73 pubmed publisher
  9. Maier S, Paulsson M, Hartmann U. The widely expressed extracellular matrix protein SMOC-2 promotes keratinocyte attachment and migration. Exp Cell Res. 2008;314:2477-87 pubmed publisher
    ..The calcium-binding domain also stimulated migration, but not proliferation of keratinocyte-like HaCaT cells. We conclude that SMOC-2, like other members of the BM40/SPARC family, acts as a regulator of cell-matrix interactions. ..

More Information

Publications374 found, 100 shown here

  1. SchAfer R, Kehlbach R, Muller M, Bantleon R, Kluba T, Ayturan M, et al. Labeling of human mesenchymal stromal cells with superparamagnetic iron oxide leads to a decrease in migration capacity and colony formation ability. Cytotherapy. 2009;11:68-78 pubmed publisher
    ..SPIO labeling with and without TA had functional effects on human mesenchymal stem cells by decreasing the migration capacity and colony-formation ability of the stem cells. ..
  2. Furundzija V, Fritzsche J, Kaufmann J, Meyborg H, Fleck E, Kappert K, et al. IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling. Biochem Biophys Res Commun. 2010;394:786-91 pubmed publisher
    ..This involves activation of integrins and focal adhesion formation via inside-out PI3-kinase/PKC/p38-dependent signaling, but does not require MMP activation. ..
  3. Leifheit Nestler M, Conrad G, Heida N, Limbourg A, Limbourg F, Seidler T, et al. Overexpression of integrin beta 5 enhances the paracrine properties of circulating angiogenic cells via Src kinase-mediated activation of STAT3. Arterioscler Thromb Vasc Biol. 2010;30:1398-406 pubmed publisher
    ..Src kinase-mediated activation of STAT3 and subsequent angiogenic gene expression mediate the effects of integrin alpha v beta 5 and may be exploited to enhance the paracrine activities of CACs. ..
  4. Halacheva V, Fuchs M, Dönitz J, Reupke T, Püschel B, Viebahn C. Planar cell movements and oriented cell division during early primitive streak formation in the mammalian embryo. Dev Dyn. 2011;240:1905-16 pubmed publisher
    ..The mammalian primitive streak appears to be formed initially with its typically minimal anteroposterior elongation by a combination of oriented cell divisions with dedicated planar cell movements. ..
  5. Haas J, Bekeredjian Ding I, Milkova M, Balint B, Schwarz A, Korporal M, et al. B cells undergo unique compartmentalized redistribution in multiple sclerosis. J Autoimmun. 2011;37:289-99 pubmed publisher
  6. Wendel C, Hemping Bovenkerk A, Krasnyanska J, Mees S, Kochetkova M, Stoeppeler S, et al. CXCR4/CXCL12 participate in extravasation of metastasizing breast cancer cells within the liver in a rat model. PLoS ONE. 2012;7:e30046 pubmed publisher
    ..Chemokine-induced extravasation of breast cancer cells along specific ECM components appears to be an important regulator but not a rate-limiting factor of their metastatic organ colonization. ..
  7. Hoyler T, Klose C, Souabni A, Turqueti Neves A, Pfeifer D, Rawlins E, et al. The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity. 2012;37:634-48 pubmed publisher
    ..Thus, our data demonstrate that GATA-3 is essential for ILC2 fate decisions and reveal similarities between the transcriptional programs controlling ILC and T helper cell fates. ..
  8. Bald T, Quast T, Landsberg J, Rogava M, Glodde N, Lopez Ramos D, et al. Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma. Nature. 2014;507:109-13 pubmed publisher
    ..Our work indicates that targeting the inflammation-induced phenotypic plasticity of melanoma cells and their association with endothelial cells represent rational strategies to specifically interfere with metastatic progression. ..
  9. Seda Kehr N, Riehemann K. Controlled Cell Growth and Cell Migration in Periodic Mesoporous Organosilica/Alginate Nanocomposite Hydrogels. Adv Healthc Mater. 2016;5:193-7 pubmed publisher
    ..The effect of the PMO concentration on cell growth and migration of cells is reported. The cells migrate in the bilayer NC hydrogel towards higher PMO concentrations and from cell culture plates to NC hydrogel scaffolds. ..
  10. Yu X, Zhao R, Lin S, Bai X, Zhang L, Yuan S, et al. CXCL16 induces angiogenesis in autocrine signaling pathway involving hypoxia-inducible factor 1α in human umbilical vein endothelial cells. Oncol Rep. 2016;35:1557-65 pubmed publisher
    ..Our data suggest that CXCL16 induces angiogenesis in autocrine manner via ERK, Akt, p38 pathways and HIF-1α modulation. ..
  11. Leibacher J, Henschler R. Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells. Stem Cell Res Ther. 2016;7:7 pubmed publisher
    ..Both preclinical and clinical studies using MSCs applied intravenously or intra-arterially are discussed in the context of our current understanding of how MSCs might work in physiological and pathological situations. ..
  12. Thangaratnarajah C, Dinger K, Vohlen C, Klaudt C, Nawabi J, López García E, et al. Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction. Am J Physiol Lung Cell Mol Physiol. 2017;313:L491-L506 pubmed publisher
    ..These new insights in pulmonary neuroimmune interaction offer potential strategies to enable lung growth. ..
  13. Klämbt C, Glazer L, Shilo B. breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes Dev. 1992;6:1668-78 pubmed
    ..In hypomorphic mutants the cells exhibit partial migration but follow the normal tracts, suggesting that the presence of this receptor is essential for the ability of the migrating cells to recognize external guiding cues. ..
  14. Homey B, Assmann T, Vohr H, Ulrich P, Lauerma A, Ruzicka T, et al. Topical FK506 suppresses cytokine and costimulatory molecule expression in epidermal and local draining lymph node cells during primary skin immune responses. J Immunol. 1998;160:5331-40 pubmed
    ..In conclusion, these results give new insights into the mechanisms of action of topical FK506 treatment. ..
  15. Senner V, Kismann E, Püttmann S, Hoess N, Baur I, Paulus W. L1 expressed by glioma cells promotes adhesion but not migration. Glia. 2002;38:146-54 pubmed
    ..Our data suggest that L1 expressed on the surface of glioma cells increases cell-matrix and intercellular adhesion, but has no apparent effects on proliferation and invasion. ..
  16. Meidenbauer N, Marienhagen J, Laumer M, Vogl S, Heymann J, Andreesen R, et al. Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients. J Immunol. 2003;170:2161-9 pubmed
    ..Overall, the results suggest that in vitro-generated Melan-A-specific CTL survive intact in vivo for several weeks and localize preferentially to tumor. ..
  17. Ott I, Michaelis C, Schuermann M, Steppich B, Seitz I, Dewerchin M, et al. Vascular remodeling in mice lacking the cytoplasmic domain of tissue factor. Circ Res. 2005;97:293-8 pubmed
    ..TF cytoplasmic domain signaling alters vascular remodeling and, thereby, may play a role in the development of restenosis, atherosclerotic disease, and neovascularization. ..
  18. Kuhlmann C, Schaefer C, Reinhold L, Tillmanns H, Erdogan A. Signalling mechanisms of SDF-induced endothelial cell proliferation and migration. Biochem Biophys Res Commun. 2005;335:1107-14 pubmed
    ..05). SDF-1-alpha increases endothelial proliferation and migration involving the activation of BK(Ca) and an increased production of NO. ..
  19. Mori T, Tanaka K, Buffo A, Wurst W, Kühn R, Gotz M. Inducible gene deletion in astroglia and radial glia--a valuable tool for functional and lineage analysis. Glia. 2006;54:21-34 pubmed
    ..Taken together, this mouse line will allow dissecting the molecular pathways regulating the diverse functions of astrocytes as precursors, support cells, repair cells, and cells involved in neuronal information processing. ..
  20. Antoine M, Wirz W, Tag C, Gressner A, Wycislo M, Muller R, et al. Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation. Biochem Biophys Res Commun. 2006;346:224-33 pubmed
    ..Therefore, the difference in the time course of MAPK activation by the different FGFs appears to be the cause for the different cellular responses. ..
  21. Huelsmann S, Hepper C, Marchese D, Knoll C, Reuter R. The PDZ-GEF dizzy regulates cell shape of migrating macrophages via Rap1 and integrins in the Drosophila embryo. Development. 2006;133:2915-24 pubmed
    ..These data provide the first link between a PDZ-GEF, the corresponding small GTPase and integrin-dependent cell adhesion during cell migration in embryonic development. ..
  22. Nattermann J, Zimmermann H, Iwan A, von Lilienfeld Toal M, Leifeld L, Nischalke H, et al. Hepatitis C virus E2 and CD81 interaction may be associated with altered trafficking of dendritic cells in chronic hepatitis C. Hepatology. 2006;44:945-54 pubmed
    ..In conclusion, migration of DC is markedly affected by interaction of HCV E2 with CD81. Failure of DC to recirculate to lymphoid tissue may be critically involved in impaired T cell priming during HCV infection. ..
  23. Zheng X, Güller S, Beissert T, Puccetti E, Ruthardt M. BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. BMC Cancer. 2006;6:262 pubmed
    ..Our data presented here describe for the first time an analysis of the biological function of the reciprocal t(9;22) ABL/BCR fusion proteins in comparison to their physiological counterpart BCR. ..
  24. Welsch T, Endlich K, Giese T, Buchler M, Schmidt J. Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization. Cancer Lett. 2007;255:205-18 pubmed
    ..We concluded that Eps8 is increased in pancreatic cancer and correlates with migratory potential and tumor progression in vitro. Eps8 is essential for actin dynamics and cell interactions, independent of Eps8-like gene products. ..
  25. Erdmann M, Dörrie J, Schaft N, Strasser E, Hendelmeier M, Kämpgen E, et al. Effective clinical-scale production of dendritic cell vaccines by monocyte elutriation directly in medium, subsequent culture in bags and final antigen loading using peptides or RNA transfection. J Immunother. 2007;30:663-74 pubmed
  26. Morath C, Reuter H, Simon V, Krautkramer E, Muranyi W, Schwenger V, et al. Effects of mycophenolic acid on human fibroblast proliferation, migration and adhesion in vitro and in vivo. Am J Transplant. 2008;8:1786-97 pubmed publisher
    ..The perspective of MPA-induced cytoskeletal dysfunction may go beyond wound healing disturbances and may have beneficial effects on (renal) allografts with respect to scarring. ..
  27. Ginzkey C, Eicker S, Marget M, Krause J, Brecht S, Westphal M, et al. Increase in tumor size following intratumoral injection of immunostimulatory CpG-containing oligonucleotides in a rat glioma model. Cancer Immunol Immunother. 2010;59:541-51 pubmed publisher
    ..However, intratumoral application proved ineffective in a rat glioma model. CpG-ODN treatment may not yield beneficial effects in glioma patients. ..
  28. Schneeweis C, Grafe M, Bungenstock A, Spencer Hänsch C, Fleck E, Goetze S. Chronic CRP-exposure inhibits VEGF-induced endothelial cell migration. J Atheroscler Thromb. 2010;17:203-12 pubmed
  29. Liebmann C. EGF receptor activation by GPCRs: an universal pathway reveals different versions. Mol Cell Endocrinol. 2011;331:222-31 pubmed publisher
    ..Several alternative mechanisms and novel aspects will be introduced. Using the example of head and neck squamous carcinoma, the potency of EGFR transactivation as a therapeutical target will be discussed. ..
  30. Schumann K, Lämmermann T, Bruckner M, Legler D, Polleux J, Spatz J, et al. Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells. Immunity. 2010;32:703-13 pubmed publisher
    ..Adhesive random migration and directional steering cooperate to produce dynamic but spatially restricted locomotion patterns closely resembling the cellular dynamics observed in secondary lymphoid organs...
  31. Blumbach K, Zweers M, Brunner G, Peters A, Schmitz M, Schulz J, et al. Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGF?1 levels and RhoA activity. J Cell Sci. 2010;123:3872-83 pubmed publisher
    ..We conclude that, in fibroblasts, ILK is crucial for limiting RhoA activity, thus promoting TGF?1 production, which is essential for dermal repair following injury...
  32. Gaiser A, Kaiser C, Haslbeck V, Richter K. Downregulation of the Hsp90 system causes defects in muscle cells of Caenorhabditis elegans. PLoS ONE. 2011;6:e25485 pubmed publisher
    ..While UNC-45 can stably bind to myofilaments in the muscular ultrastructure, Hsp90 (DAF-21) appears to participate in the maintenance of muscle structures as a transiently associated diffusible factor...
  33. Keilberg D, Wuichet K, Drescher F, Søgaard Andersen L. A response regulator interfaces between the Frz chemosensory system and the MglA/MglB GTPase/GAP module to regulate polarity in Myxococcus xanthus. PLoS Genet. 2012;8:e1002951 pubmed publisher
  34. Elfimova N, Sievers E, Eischeid H, Kwiecinski M, Noetel A, Hunt H, et al. Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration. Biochim Biophys Acta. 2013;1833:1190-8 pubmed publisher
    ..In conclusion, miR-198 acts as a tumor suppressor by repression of mitogenic and motogenic pathways diminishing cell growth and migration. ..
  35. Hirsch E, Iglesias A, Potocnik A, Hartmann U, Fassler R. Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins. Nature. 1996;380:171-5 pubmed
    ..Our results indicate that haematopoietic stem cells lacking beta1 integrins can form and differentiate into different lineages but cannot colonize the fetal liver. ..
  36. Protin U, Schweighoffer T, Jochum W, Hilberg F. CD44-deficient mice develop normally with changes in subpopulations and recirculation of lymphocyte subsets. J Immunol. 1999;163:4917-23 pubmed
    ..Our data indicate that all splice variants of CD44 are dispensable for embryonic development and implicate a critical function for CD44 in lymphocyte recirculation. ..
  37. Schwab A. Function and spatial distribution of ion channels and transporters in cell migration. Am J Physiol Renal Physiol. 2001;280:F739-47 pubmed
    ..Moreover, a model is proposed that combines ion transport with cytoskeletal mechanisms of migration...
  38. Butt E, Gambaryan S, Göttfert N, Galler A, Marcus K, Meyer H. Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146. J Biol Chem. 2003;278:15601-7 pubmed
    ..Taken together, these data suggest that phosphorylation of LASP by cGK and cAK may be involved in cytoskeletal organization and cell motility. ..
  39. Happel P, Hoffmann G, Mann S, Dietzel I. Monitoring cell movements and volume changes with pulse-mode scanning ion conductance microscopy. J Microsc. 2003;212:144-51 pubmed
    ..Difference images indicate that volume changes can affect cell surfaces inhomogeneously, emphasizing the role of the cytoskeleton in the stabilization of cell shape. ..
  40. Gilmour D, Knaut H, Maischein H, NUSSLEIN VOLHARD C. Towing of sensory axons by their migrating target cells in vivo. Nat Neurosci. 2004;7:491-2 pubmed
    ..Here we combine genetics and time-lapse imaging in the zebrafish to show that towing by migrating cells is a bona fide mechanism for guiding pathfinding axons in vivo. ..
  41. Kaufmann A, Musset B, Limberg S, Renigunta V, Sus R, Dalpke A, et al. "Host tissue damage" signal ATP promotes non-directional migration and negatively regulates toll-like receptor signaling in human monocytes. J Biol Chem. 2005;280:32459-67 pubmed
    ..Thus, our data suggest that ATP promotes non-directional migration and, importantly, acts as a "host tissue damage" signal via the G(s) protein-coupled P2Y(11) receptor and increased cAMP to negatively regulate TLR signaling. ..
  42. Maretzky T, Schulte M, Ludwig A, Rose John S, Blobel C, Hartmann D, et al. L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth. Mol Cell Biol. 2005;25:9040-53 pubmed
    ..Thus, our data identify ADAM10 and ADAM17 as differentially regulated L1 membrane sheddases, both critically affecting the physiological functions of this adhesion protein. ..
  43. Bixel M, Petri B, Khandoga A, Khandoga A, Wolburg Buchholz K, Wolburg H, et al. A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo. Blood. 2007;109:5327-36 pubmed
    ..Our results establish CD99L2 as a new endothelial surface protein involved in neutrophil extravasation. In addition, this is the first evidence for a role of CD99 and CD99L2 in the process of leukocyte diapedesis in vivo. ..
  44. Schröder K, Helmcke I, Palfi K, Krause K, Busse R, Brandes R. Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2007;27:1736-43 pubmed
    ..These data demonstrate that bFGF activates the Nox1-containing NADPH oxidase and that bFGF through a pathway involving ROS and JNK stimulates SMC migration. ..
  45. Finzsch M, Stolt C, Lommes P, Wegner M. Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development. 2008;135:637-46 pubmed publisher
    ..We thus conclude that Sox9 and Sox10 are required in a functionally redundant manner in oligodendrocyte precursors for PDGF-dependent survival and migration. ..
  46. Urbich C, Dernbach E, Rossig L, Zeiher A, Dimmeler S. High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells. J Mol Cell Cardiol. 2008;45:429-36 pubmed publisher
  47. Schwab A, Hanley P, Fabian A, Stock C. Potassium channels keep mobile cells on the go. Physiology (Bethesda). 2008;23:212-20 pubmed publisher
    ..Studies over the past few years have revealed that ion channels are essential for cell motility. This review highlights the importance of K+ channels in regulating cell motility. ..
  48. Heisenberg C, Solnica Krezel L. Back and forth between cell fate specification and movement during vertebrate gastrulation. Curr Opin Genet Dev. 2008;18:311-6 pubmed publisher
    ..The current challenge is to delineate the molecular mechanisms via which the major signaling pathways regulate cell fate specification and movements, and how these two processes are coordinated to ensure normal development. ..
  49. Neumann E, Lefèvre S, Zimmermann B, Geyer M, Lehr A, Umscheid T, et al. Migratory potential of rheumatoid arthritis synovial fibroblasts: additional perspectives. Cell Cycle. 2010;9:2286-91 pubmed
  50. Seidler S, Zimmermann H, Bartneck M, Trautwein C, Tacke F. Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults. BMC Immunol. 2010;11:30 pubmed publisher
  51. Fricke R, Zentis P, Rajappa L, Hofmann B, Banzet M, Offenhäusser A, et al. Axon guidance of rat cortical neurons by microcontact printed gradients. Biomaterials. 2011;32:2070-6 pubmed publisher
    ..It could thereby be useful to engineer defined neural networks for analyzing signal processing of functional circuits, as well as to unravel fundamental questions of the axon guidance mechanism. ..
  52. Doller A, Winkler C, Azrilian I, Schulz S, Hartmann S, Pfeilschifter J, et al. High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells. Carcinogenesis. 2011;32:676-85 pubmed publisher
    ..Our data suggest that the increased HuR phosphorylation at Ser 318 by PKC? reflects an important regulatory paradigm for aberrant HuR functions and emphasize the antitumorigenic potential of PKC? inhibitory strategies. ..
  53. Berer K, Mues M, Koutrolos M, Rasbi Z, Boziki M, Johner C, et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature. 2011;479:538-41 pubmed publisher
    ..Our observations identify a sequence of events triggering organ-specific autoimmune disease and these processes may offer novel therapeutic targets. ..
  54. Ernst S, Liu K, Agarwala S, Moratscheck N, Avci M, Dalle Nogare D, et al. Shroom3 is required downstream of FGF signalling to mediate proneuromast assembly in zebrafish. Development. 2012;139:4571-81 pubmed publisher
    ..In conclusion, we uncovered the first mechanistic link between patterning and morphogenesis during LL sensory organ formation. ..
  55. Senger S, Kollmar O, Menger M, Rupertus K. Darbepoetin-α Promotes Cell Proliferation in Established Extrahepatic Colorectal Tumors after Major Hepatectomy. Eur Surg Res. 2016;56:49-60 pubmed publisher
    ..Thus, DPO may not be recommended to stimulate regeneration of the remnant liver after major hepatectomy for colorectal liver metastasis. ..
  56. Yu P, Wilhelm K, Dubrac A, Tung J, Alves T, Fang J, et al. FGF-dependent metabolic control of vascular development. Nature. 2017;545:224-228 pubmed publisher
    ..Thus, FGF-dependent regulation of endothelial glycolysis is a pivotal process in developmental and adult vascular growth and development. ..
  57. Jungbauer F, Aderhold C, Birk R, Hoermann K, Krämer B, Kuhlin B, et al. Communicate or Die - A Model for HPV+ and HPV- CSCs and Their Interactions with SDF-1?. Anticancer Res. 2017;37:4827-4836 pubmed
    ..Weakened reaction to SDF-1? in HPV+ SCC could lead to an impaired communication between CSCs and their niche, that would result in an increased exposure of CSCs to the harming influence of e.g. chemotherapeutic agents. ..
  58. Varga J, Greten F. Cell plasticity in epithelial homeostasis and tumorigenesis. Nat Cell Biol. 2017;19:1133-1141 pubmed publisher
    ..Here we review recent advances in this field with a focus on cell fate changes and the epithelial-mesenchymal transition-two distinct, yet closely related, forms of plasticity with fundamental roles in homeostasis and cancer. ..
  59. Kramer R, Zhang Y, Gehrmann J, Gold R, Thoenen H, Wekerle H. Gene transfer through the blood-nerve barrier: NGF-engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis. Nat Med. 1995;1:1162-6 pubmed
    ..Local release of NGF from engineered T cells was demonstrable by immunocytochemistry and by an anti-inflammatory effect on infiltrating macrophages. ..
  60. Nockher W, Wiemer J, Scherberich J. Haemodialysis monocytopenia: differential sequestration kinetics of CD14+CD16+ and CD14++ blood monocyte subsets. Clin Exp Immunol. 2001;123:49-55 pubmed
    ..This sequestration kinetics may be due to a distinct surface expression of major adhesion receptors which facilitate leucocyte-leucocyte, as well as leucocyte-endothelial, interactions. ..
  61. Viebahn C, Stortz C, Mitchell S, Blum M. Low proliferative and high migratory activity in the area of Brachyury expressing mesoderm progenitor cells in the gastrulating rabbit embryo. Development. 2002;129:2355-65 pubmed
    ..Rather, rabbit epiblast cells start mesoderm differentiation in a way similar to Drosophila, where a transient downregulation of proliferation initiates mesoderm differentiation and, hence, gastrulation. ..
  62. Hafner C, Knuechel R, Stoehr R, Hartmann A. Clonality of multifocal urothelial carcinomas: 10 years of molecular genetic studies. Int J Cancer. 2002;101:1-6 pubmed
    ..Investigation of the entire urothelial lining in patients with urothelial tumors should provide further insight into the development of multifocal urothelial carcinomas. ..
  63. Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, et al. YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta. J Cell Biol. 2004;164:1009-20 pubmed
  64. Kunzmann V, Wilhelm M. Anti-lymphoma effect of gammadelta T cells. Leuk Lymphoma. 2005;46:671-80 pubmed
  65. Voisard R, Alan M, von Muller L, Baur R, Hombach V. Effects of abciximab on key pattern of human coronary restenosis in vitro: impact of the SI/MPL-ratio. BMC Cardiovasc Disord. 2006;6:14 pubmed
    ..Thus, the anti-restenotic effects of systemically administered abciximab reported in the ISAR-SWEET-study were not caused by a direct inhibitory effect on ICAM-1 expression, migration or proliferation. ..
  66. Neuhaus P, Jaschinsky B, Schneider S, Neuhaus H, Wolter A, Ebelt H, et al. Overexpression of Kelch domain containing-2 (mKlhdc2) inhibits differentiation and directed migration of C2C12 myoblasts. Exp Cell Res. 2006;312:3049-59 pubmed
    ..Our results suggest that a tightly controlled expression of mKlhdc2 is essential for a faithful execution of the myogenic differentiation and migration program. ..
  67. Engel D, Dobrindt U, Tittel A, Peters P, Maurer J, Gütgemann I, et al. Tumor necrosis factor alpha- and inducible nitric oxide synthase-producing dendritic cells are rapidly recruited to the bladder in urinary tract infection but are dispensable for bacterial clearance. Infect Immun. 2006;74:6100-7 pubmed
    ..These findings demonstrate that some of the abundant DC recruited in UTI contributed innate immune effector functions, which were, however, dispensable in the microenvironment of the bladder. ..
  68. Edenfeld G, Altenhein B, Zierau A, Cleppien D, Krukkert K, Technau G, et al. Notch and Numb are required for normal migration of peripheral glia in Drosophila. Dev Biol. 2007;301:27-37 pubmed
  69. Christian S, Winkler R, Helfrich I, Boos A, Besemfelder E, Schadendorf D, et al. Endosialin (Tem1) is a marker of tumor-associated myofibroblasts and tumor vessel-associated mural cells. Am J Pathol. 2008;172:486-94 pubmed publisher
  70. Mahlknecht U, Schonbein C. Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells. Haematologica. 2008;93:443-6 pubmed publisher
  71. Aicher A, Kollet O, Heeschen C, Liebner S, Urbich C, Ihling C, et al. The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche. Circ Res. 2008;103:796-803 pubmed publisher
    ..Thus, these data show that Dkk-1 is a mobilizer of vasculogenic progenitors but not of inflammatory cells, which could be of great clinical importance to enhance regenerative cell therapy. ..
  72. Heinrich D, Youssef S, Schroth Diez B, Engel U, Aydin D, Blümmel J, et al. Actin-cytoskeleton dynamics in non-monotonic cell spreading. Cell Adh Migr. 2008;2:58-68 pubmed
    ..We conclude that non-monotonic cell spreading is characterized by spatiotemporal patterns formed by motor proteins together with regulatory proteins that either promote or terminate actin polymerization on the scale of seconds. ..
  73. Amann T, Maegdefrau U, Hartmann A, Agaimy A, Marienhagen J, Weiss T, et al. GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis. Am J Pathol. 2009;174:1544-52 pubmed publisher
    ..In summary, our findings suggest that increased GLUT1 expression levels in HCC cells functionally affect tumorigenicity, and thus, we propose GLUT1 as an innovative therapeutic target for this highly aggressive tumor. ..
  74. Kardash E, Reichman Fried M, Maître J, Boldajipour B, Papusheva E, Messerschmidt E, et al. A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo. Nat Cell Biol. 2010;12:47-53; sup pp 1-11 pubmed publisher
  75. Andrzejewski M, Koelsch A, Kogel T, Dreymueller D, Schwarz N, Ludwig A. Distinct role of the intracellular C-terminus for subcellular expression, shedding and function of the murine transmembrane chemokine CX3CL1. Biochem Biophys Res Commun. 2010;395:178-84 pubmed publisher
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