Experts and Doctors on casein kinase i in United Kingdom
Locale: United Kingdom
Topic: casein kinase i
Huart A, Saxty B, Merritt A, Nekulova M, Lewis S, Huang Y, et al
. A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novel activator of the p53 pathway. Bioorg Med Chem Lett. 2013;23:5578-85 pubmed publisher
..These data demonstrate the emerging potential utility of multivalent kinase inhibitors. ..
Price M. CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes Dev. 2006;20:399-410 pubmed
..Here I review these roles, including recent results on casein kinase I (CKI) phosphorylation and activation of LRP6, and CKI phosphorylation of Ci and mediation of Ci-Slimb/beta-TrCP binding. ..
van Ooijen G, Hindle M, Martin S, Barrios Llerena M, Sanchez F, Bouget F, et al
. Functional analysis of Casein Kinase 1 in a minimal circadian system. PLoS ONE. 2013;8:e70021 pubmed publisher
..These results have major implications for our understanding of cellular timekeeping and can inform future studies in any circadian organism. ..
MacLaine N, Oster B, Bundgaard B, Fraser J, Buckner C, Lazo P, et al
. A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection. J Biol Chem. 2008;283:28563-73 pubmed publisher