Experts and Doctors on bone marrow cells in Australia


Locale: Australia
Topic: bone marrow cells

Top Publications

  1. Old J, Selwood L, Deane E. The appearance and distribution of mature T and B cells in the developing immune tissues of the stripe-faced dunnart (Sminthopsis macroura). J Anat. 2004;205:25-33 pubmed
  2. Wei A, Tao H, Chung S, Brisby H, Ma D, Diwan A. The fate of transplanted xenogeneic bone marrow-derived stem cells in rat intervertebral discs. J Orthop Res. 2009;27:374-9 pubmed publisher
    ..Our data provide evidence that transplanted human BM CD34(-) cells survived and differentiated within the relative immune privileged nucleus pulposus of intervertebral disc degeneration. ..
  3. Papathanasiou P, Petvises S, Hey Y, Perkins A, O Neill H. Impact of the c-MybE308G mutation on mouse myelopoiesis and dendritic cell development. PLoS ONE. 2017;12:e0176345 pubmed publisher
    ..An alternative explanation may be needed for why there was no change in CD8+ cDCs in booreana spleen since these cells are known to derive from common dendritic progenitors in bone marrow. ..
  4. Shen W, Bendall L, Gottlieb D, Bradstock K. The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. Exp Hematol. 2001;29:1439-47 pubmed
    ..These data show that SDF-1 and CXCR4 are involved in regulation of beta1 integrin function, and are important for the localization of pre-B cells to the bone marrow in vivo. ..
  5. Dudakov J, Goldberg G, Reiseger J, Vlahos K, Chidgey A, Boyd R. Sex steroid ablation enhances hematopoietic recovery following cytotoxic antineoplastic therapy in aged mice. J Immunol. 2009;183:7084-94 pubmed publisher
    ..Taken together, these results provide the basis for the use of SSA in the clinic to enhance treatment outcomes from cytotoxic antineoplastic therapy. ..
  6. Dyer A, Burdock G, Carabin I, Haas M, Boyce J, Alsaker R, et al. In vitro and in vivo safety studies of a proprietary whey extract. Food Chem Toxicol. 2008;46:1659-65 pubmed publisher
    ..The results from the genotoxicity studies and the subchronic oral toxicity study suggest Lactermin is safe for consumption with a no-observed-adverse-effect level (NOAEL) of 3000 mg/kg/day. ..
  7. Briscoe H, Roach D, Meadows N, Rathjen D, Britton W. A novel tumor necrosis factor (TNF) mimetic peptide prevents recrudescence of Mycobacterium bovis bacillus Calmette-Guerin (BCG) infection in CD4+ T cell-depleted mice. J Leukoc Biol. 2000;68:538-44 pubmed
    ..Granuloma number and bacterial load were comparable in treated, T cell-depleted mice and in chronically infected, intact animals. Thus, TNF70-80 and hTNF can modulate recrudescent BCG infection in CD4+ T cell-deficient mice. ..
  8. Banovic T, Markey K, Kuns R, Olver S, Raffelt N, Don A, et al. Graft-versus-host disease prevents the maturation of plasmacytoid dendritic cells. J Immunol. 2009;182:912-20 pubmed
    ..These data demonstrate that GVHD prevents the maturation of pDC and instead promotes the generation of a suppressive precursor DC, further contributing to the state of immune paralysis after transplantation. ..
  9. Qi J, Wang J, Mandadi S, Tanaka K, Roufogalis B, Madigan M, et al. Human and mouse mast cells use the tetraspanin CD9 as an alternate interleukin-16 receptor. Blood. 2006;107:135-42 pubmed
    ..This is the first report of a tetraspanin that plays a prominent role in a cytokine-mediated chemotactic response of human MCs. ..

More Information


  1. Perkins A, Cory S. Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene. EMBO J. 1993;12:3835-46 pubmed
    ..Thus ectopic expression of Hox-2.4 enhances self-renewal of immature myeloid progenitors and progression to a fully malignant state is favoured by somatic mutations conferring autocrine production of IL-3. ..
  2. Gronthos S, McCarty R, Mrozik K, Fitter S, Paton S, Menicanin D, et al. Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues. Stem Cells Dev. 2009;18:1253-62 pubmed publisher
    ..In addition to identifying an antibody reagent that identifies a highly conserved epitope expressed by MSCs from different species, our study also points to a potential role for Hsp90beta in MSC biology. ..
  3. Ludlow L, Purton L, Klarmann K, Gough D, Hii L, Trapani J, et al. The role of p202 in regulating hematopoietic cell proliferation and differentiation. J Interferon Cytokine Res. 2008;28:5-11 pubmed publisher
    ..Thus, p202 plays a role in regulating the proliferative capacity of hematopoietic cells. ..
  4. Fan W, Crawford R, Xiao Y. The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization. Differentiation. 2011;81:181-91 pubmed publisher
  5. Tallack M, Perkins A. Megakaryocyte-erythroid lineage promiscuity in EKLF null mouse blood. Haematologica. 2010;95:144-7 pubmed publisher
    ..We conclude the megakaryocyte program is aberrantly activated in EKLF null erythroid cells. ..
  6. Lattin J, Greenwood K, Daly N, Kelly G, Zidar D, Clark R, et al. Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Mol Immunol. 2009;47:340-7 pubmed publisher
    ..Given that loss of C1q function is strongly associated with the development of systemic lupus erythematosus, ARRB2 may act to limit the development of autoimmune disease. ..
  7. Gaundar S, Bradstock K, Bendall L. p38MAPK inhibitors attenuate cytokine production by bone marrow stromal cells and reduce stroma-mediated proliferation of acute lymphoblastic leukemia cells. Cell Cycle. 2009;8:2975-83 pubmed
    ..These findings suggest that inhibition of p38(MAPK) may provide a useful adjunct to current treatment strategies by retarding ALL cell growth. ..
  8. Chung R, Foster B, Zannettino A, Xian C. Potential roles of growth factor PDGF-BB in the bony repair of injured growth plate. Bone. 2009;44:878-85 pubmed publisher
    ..These results suggest that PDGF-BB contributes to growth plate injury repair by promoting mesenchymal progenitor cell infiltration, the chondrogenic and osteogenic responses, and remodelling of the repair tissues. ..
  9. Juarez J, Baraz R, Gaundar S, Bradstock K, Bendall L. Interaction of interleukin-7 and interleukin-3 with the CXCL12-induced proliferation of B-cell progenitor acute lymphoblastic leukemia. Haematologica. 2007;92:450-9 pubmed
  10. Hamilton J, Anderson G. GM-CSF Biology. Growth Factors. 2004;22:225-31 pubmed
    ..g. as an adjuvant, and also includes those observed in depletion studies, e.g. during inflammatory reactions where GM-CSF can be shown to have a proinflammatory action. ..
  11. Zhou W, Zhao Q, Sutton R, Cumming H, Wang X, Cerruti L, et al. The role of p22 NF-E4 in human globin gene switching. J Biol Chem. 2004;279:26227-32 pubmed
    ..These findings indicate that p22 NF-E4 is capable of influencing human globin gene expression in vivo but is incapable of overriding the intrinsic mechanisms governing gamma-gene silencing in this context. ..
  12. Thomas G, Costelloe E, Lunn D, Stacey K, Delaney S, Passey R, et al. G551D cystic fibrosis mice exhibit abnormal regulation of inflammation in lungs and macrophages. J Immunol. 2000;164:3870-7 pubmed
    ..These results provide evidence that the pathology of CF relates to abnormal regulation of the immune system. ..