Experts and Doctors on biological models in Austria

Summary

Locale: Austria
Topic: biological models

Top Publications

  1. Kuznetsov A, Hermann M, Saks V, Hengster P, Margreiter R. The cell-type specificity of mitochondrial dynamics. Int J Biochem Cell Biol. 2009;41:1928-39 pubmed publisher
  2. Petzelbauer I, Kuhn B, Splechtna B, Kulbe K, Nidetzky B. Development of an ultrahigh-temperature process for the enzymatic hydrolysis of lactose. IV. Immobilization of two thermostable beta-glycosidases and optimization of a packed-bed reactor for lactose conversion. Biotechnol Bioeng. 2002;77:619-31 pubmed
    ..Formation of galacto-oligosaccharides in the continuous packed-bed reactor and in the batch reactor using free enzyme was closely similar in regard to yield and individual saccharide components produced. ..
  3. Jantschko W, Furtmüller P, Zederbauer M, Neugschwandtner K, Jakopitsch C, Obinger C. Reaction of ferrous lactoperoxidase with hydrogen peroxide and dioxygen: an anaerobic stopped-flow study. Arch Biochem Biophys. 2005;434:51-9 pubmed
    ..The relevance of these findings in LPO catalysis is discussed. ..
  4. Glotzer M. Cleavage furrow positioning. J Cell Biol. 2004;164:347-51 pubmed
    ..Although the mechanism of cleavage furrow positioning is not understood at a molecular level, recent results suggest that it might be mediated by local relief from the inhibitory effects of microtubules. ..
  5. Martinez J, Busslinger M. Life beyond cleavage: the case of Ago2 and hematopoiesis. Genes Dev. 2007;21:1983-8 pubmed
  6. Peters J, Tedeschi A, Schmitz J. The cohesin complex and its roles in chromosome biology. Genes Dev. 2008;22:3089-114 pubmed publisher
  7. Schneider W. Receptor-mediated mechanisms in ovarian follicle and oocyte development. Gen Comp Endocrinol. 2009;163:18-23 pubmed publisher
  8. Neuhaus W, Lauer R, Oelzant S, Fringeli U, Ecker G, Noe C. A novel flow based hollow-fiber blood-brain barrier in vitro model with immortalised cell line PBMEC/C1-2. J Biotechnol. 2006;125:127-41 pubmed
    ..g., regulation of BBB permeability), pharmacological (e.g., pharmacokinetics and dynamics) and pathophysiological (e.g., effects of diseases on BBB permeability and vice versa) objectives. ..
  9. Modre Osprian R, Osprian I, Tilg B, Schreier G, Weinberger K, Graber A. Dynamic simulations on the mitochondrial fatty acid beta-oxidation network. BMC Syst Biol. 2009;3:2 pubmed publisher
    ..Our findings offer insight into the disease process (e.g. rapid progress to coma) and might confirm new explanations (no human cases of LCAD deficiency), which can hardly be obtained from experimental data alone. ..

More Information

Publications101 found, 100 shown here

  1. Schett G, Steiner C, Xu Q, Smolen J, Steiner G. TNFalpha mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress response. Cell Death Differ. 2003;10:1126-36 pubmed
    ..The price of inhibition of an essential cellular stress response is increased sensitivity to apoptotic cell death. ..
  2. Griffioen G, Branduardi P, Ballarini A, Anghileri P, Norbeck J, Baroni M, et al. Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain. Mol Cell Biol. 2001;21:511-23 pubmed
    ..Altogether, these results suggest that Zds1-mediated cytoplasmic localization of Bcy1 is regulated by carbon source-dependent phosphorylation of cluster II serines, while cluster I acts in a Zds1-independent manner. ..
  3. Korkhov V, Farhan H, Freissmuth M, Sitte H. Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II. J Biol Chem. 2004;279:55728-36 pubmed
  4. Hardmeier R, Redl H, Marlovits S. Effects of mechanical loading on collagen propeptides processing in cartilage repair. J Tissue Eng Regen Med. 2010;4:1-11 pubmed publisher
    ..These effects seemed to be dependent on the magnitude and duration of the physical stress. This review will contribute to the understanding of mechanisms for collagen assembly in both a natural and an artificial environment. ..
  5. Schneditz D, Platzer D, Daugirdas J. A diffusion-adjusted regional blood flow model to predict solute kinetics during haemodialysis. Nephrol Dial Transplant. 2009;24:2218-24 pubmed publisher
    ..This new model should be applicable to modelling of other non-protein-bound candidate uraemic toxins, also. ..
  6. Furuhashi T, Schwarzinger C, Miksik I, Smrz M, Beran A. Molluscan shell evolution with review of shell calcification hypothesis. Comp Biochem Physiol B Biochem Mol Biol. 2009;154:351-71 pubmed publisher
    ..DMMB staining data inferred that sulphated groups present in aplacophoran cuticle but not in polyplacophorans cuticle. These insight suggested importance of comparison between acuriferans and conchiferans. ..
  7. Yu J, Dickson B. Sexual behaviour: do a few dead neurons make the difference?. Curr Biol. 2006;16:R23-5 pubmed
    ..Might this explain why males and females have such distinct sexual behaviours? ..
  8. Hosiner D, Lempiäinen H, Reiter W, Urban J, Loewith R, Ammerer G, et al. Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response. Mol Biol Cell. 2009;20:1048-57 pubmed publisher
    ..Thus arsenic toxicity in yeast might be determined by the balance between chronic activation of general stress factors in combination with lowered TORC1 kinase activity. ..
  9. Kovatcheva A, Golbraikh A, Oloff S, Feng J, Zheng W, Tropsha A. QSAR modeling of datasets with enantioselective compounds using chirality sensitive molecular descriptors. SAR QSAR Environ Res. 2005;16:93-102 pubmed
  10. Lirk P, Bodrogi F, Raifer H, Greiner K, Ulmer H, Rieder J. Elective haemodialysis increases exhaled isoprene. Nephrol Dial Transplant. 2003;18:937-41 pubmed
    ..We therefore propose to perform online monitoring of isoprene exhalation by PTR-MS during the HD session to investigate the possible influence of respiratory variables. ..
  11. Kun A, Boza G, Scheuring I. Cooperators Unite! Assortative linking promotes cooperation particularly for medium sized associations. BMC Evol Biol. 2010;10:173 pubmed publisher
    ..Observations about the number of partners in natural cooperating groups are in concordance with the result of our model. ..
  12. Elfgang C, Rosorius O, Hofer L, Jaksche H, Hauber J, Bevec D. Evidence for specific nucleocytoplasmic transport pathways used by leucine-rich nuclear export signals. Proc Natl Acad Sci U S A. 1999;96:6229-34 pubmed
  13. Fritscher K, Grunerbl A, Hanni M, Suhm N, Hengg C, Schubert R. Trabecular bone analysis in CT and X-ray images of the proximal femur for the assessment of local bone quality. IEEE Trans Med Imaging. 2009;28:1560-75 pubmed publisher
  14. Distelmaier K, Adlbrecht C, Jakowitsch J, Winkler S, Dunkler D, Gerner C, et al. Local complement activation triggers neutrophil recruitment to the site of thrombus formation in acute myocardial infarction. Thromb Haemost. 2009;102:564-72 pubmed publisher
    ..We present the first direct evidence for localised complement activation in acute coronary thrombi. Our data indicate that local complement effectors amplify the vascular occlusion process in AMI by enhanced neutrophil recruitment. ..
  15. Mitteroecker P, Gunz P, Weber G, Bookstein F. Regional dissociated heterochrony in multivariate analysis. Ann Anat. 2004;186:463-70 pubmed
    ..The relation between these two species' growth trajectories is too complex for a simple summary in terms of global heterochrony. ..
  16. Sallacz N, Jantsch M. Chromosomal storage of the RNA-editing enzyme ADAR1 in Xenopus oocytes. Mol Biol Cell. 2005;16:3377-86 pubmed
    ..Nuclear injection of RNAs providing binding sites for ADAR1 dissociates the enzyme from the special loop, supporting the notion that the special loop represents a site where ADAR1 is stored, possibly for later use during development. ..
  17. Zahrl D, Wagner M, Bischof K, Koraimann G. Expression and assembly of a functional type IV secretion system elicit extracytoplasmic and cytoplasmic stress responses in Escherichia coli. J Bacteriol. 2006;188:6611-21 pubmed
    ..Stimulation of rpoHp(1) was dependent on the presence of CpxR, suggesting a hitherto undocumented link between CpxAR and sigma(32)-regulated stress networks. ..
  18. Ansari Shahrezaei S, Maar N, Biowski R, Stur M. Biomicroscopic measurement of the optic disc with a high-power positive lens. Invest Ophthalmol Vis Sci. 2001;42:153-7 pubmed
    ..These findings have important implications for the way in which calculations for determining the true optic disc size and other structures of the posterior pole are performed using indirect biomicroscopy. ..
  19. Komon Zelazowska M, Neuhof T, Dieckmann R, von Döhren H, Herrera Estrella A, Kubicek C, et al. Formation of atroviridin by Hypocrea atroviridis is conidiation associated and positively regulated by blue light and the G protein GNA3. Eukaryot Cell. 2007;6:2332-42 pubmed
    ..Our data show that formation of atroviridin by H. atroviridis occurs in a sporulation-associated manner but is uncoupled from it at the stage of GNA3...
  20. Winter N, Kollwig G, Zhang S, Kragler F. MPB2C, a microtubule-associated protein, regulates non-cell-autonomy of the homeodomain protein KNOTTED1. Plant Cell. 2007;19:3001-18 pubmed
    ..These findings are discussed in terms of the role played by MPB2C proteins in regulating the cell-to-cell trafficking of homeodomain proteins in plants. ..
  21. Kostner G, Wo X, Frank S, Kostner K, Zimmermann R, Steyrer E. Metabolism of Lp(a): assembly and excretion. Clin Genet. 1997;52:347-54 pubmed
    ..Strategies for reducing plasma Lp(a) levels with medication should aim at interfering with the assembly of Lp(a) on one hand and the stimulation of apo(a) fragmentation on the other hand. ..
  22. Daum G, Wagner A, Czabany T, Grillitsch K, Athenstaedt K. Lipid storage and mobilization pathways in yeast. Novartis Found Symp. 2007;286:142-51; discussion 151-4, 162-3, 196-203 pubmed
    ..Consequently, regulation of neutral lipid metabolism does not only occur at the enzymatic level but also at the organelle level. ..
  23. Weichhart T, Saemann M. The multiple facets of mTOR in immunity. Trends Immunol. 2009;30:218-26 pubmed publisher
    ..These results place mTOR in a novel immunoregulatory context that highlights the potential of mTOR inhibitors as both immunosuppressant and anti-cancer agents. ..
  24. Keckes J, Burgert I, Frühmann K, Muller M, Kölln K, Hamilton M, et al. Cell-wall recovery after irreversible deformation of wood. Nat Mater. 2003;2:810-4 pubmed
    ..We suggest that the molecular recovery mechanism in the cell matrix is a universal phenomenon dominating the tensile deformation of different wood tissue types. ..
  25. Regelsberger G, Laaha U, Dietmann D, Ruker F, Canini A, Grilli Caiola M, et al. The iron superoxide dismutase from the filamentous cyanobacterium Nostoc PCC 7120. Localization, overexpression, and biochemical characterization. J Biol Chem. 2004;279:44384-93 pubmed
  26. Vietor I, Kurzbauer R, Brosch G, Huber L. TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent. J Biol Chem. 2005;280:39795-801 pubmed
  27. Fritsch A, Hellmich C. 'Universal' microstructural patterns in cortical and trabecular, extracellular and extravascular bone materials: micromechanics-based prediction of anisotropic elasticity. J Theor Biol. 2007;244:597-620 pubmed
  28. Fröls S, White M, Schleper C. Reactions to UV damage in the model archaeon Sulfolobus solfataricus. Biochem Soc Trans. 2009;37:36-41 pubmed publisher
    ..The present review summarizes and discusses recent investigations on the UV response of S. solfataricus on both the molecular biological and the cellular levels. ..
  29. Lackner C, Daufeldt S, Wildt L, Allera A. Glucocorticoid-recognizing and -effector sites in rat liver plasma membrane. Kinetics of corticosterone uptake by isolated membrane vesicles. III. Specificity and stereospecificity. J Steroid Biochem Mol Biol. 1998;64:69-82 pubmed
    ..The GC importer seems to be an additional link in the chain of steroid signal transduction and may be functionally involved in the action of natural GC-agonists and GC-antagonists. ..
  30. Malli R, Frieden M, Hunkova M, Trenker M, Graier W. Ca2+ refilling of the endoplasmic reticulum is largely preserved albeit reduced Ca2+ entry in endothelial cells. Cell Calcium. 2007;41:63-76 pubmed publisher
    ..Our data indicate that ER refilling occurs in priority to, and independently from the cytosolic Ca2+ elevation upon Ca2+ entry and that this important process is widely achieved even under conditions of diminished Ca2+entry. ..
  31. Eisenhaber B, Schneider G, Wildpaner M, Eisenhaber F. A sensitive predictor for potential GPI lipid modification sites in fungal protein sequences and its application to genome-wide studies for Aspergillus nidulans, Candida albicans, Neurospora crassa, Saccharomyces cerevisiae and Schizosaccharomyces po. J Mol Biol. 2004;337:243-53 pubmed
    ..Lists of potentially GPI lipid anchored proteins for five fungal proteomes have been generated and the hits have been functionally classified. The fungal big-Pi prediction WWW server as well as precursor lists are available at ..
  32. Keleman K, Ribeiro C, Dickson B. Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo. Nat Neurosci. 2005;8:156-63 pubmed
    ..We show here, however, that ubiquitination of Comm is not required for its function in vitro or in vivo, and that Nedd4 is unlikely to function in axon guidance at the midline. ..
  33. Zollner G, Wagner M, Moustafa T, Fickert P, Silbert D, Gumhold J, et al. Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids. Am J Physiol Gastrointest Liver Physiol. 2006;290:G923-32 pubmed
    ..The induction of bile acid hydroxylation and Mrp4 was independent of FXR but could not counteract liver toxicity sufficiently. Limited effects of UDCA on Ost-alpha/Ost-beta may jeopardize its therapeutic efficacy. ..
  34. Seidl C, Stricker S, Barlow D. The imprinted Air ncRNA is an atypical RNAPII transcript that evades splicing and escapes nuclear export. EMBO J. 2006;25:3565-75 pubmed publisher
    ..These features show that Air is an atypical RNAPII transcript whose properties indicate that its mode of action in gene silencing may not depend on the RNA per se but instead is related to its actual transcription...
  35. Fischer H, Schlagbauer M. Localization of activities in the human body with a whole-body counter. Radiat Prot Dosimetry. 2007;125:488-91 pubmed
    ..Measurements show that these radionuclides can be located within 1.5 cm along the longitudinal axis of the phantom with activities for 137Cs of at least 240 Bq, 133Ba of at least 670 Bq and 60Co of at least 140 Bq. ..
  36. Resch A, Afonyushkin T, Lombo T, McDowall K, Blasi U, Kaberdin V. Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5'-leader. RNA. 2008;14:454-9 pubmed publisher
    ..This study provides new insights into regulation by small regulatory RNAs in that the molecular function of DsrA not only facilitates ribosome loading on rpoS mRNA, but additionally involves an alternative processing of the target. ..
  37. Zarschler K, Janesch B, Zayni S, Schäffer C, Messner P. Construction of a gene knockout system for application in Paenibacillus alvei CCM 2051T, exemplified by the S-layer glycan biosynthesis initiation enzyme WsfP. Appl Environ Microbiol. 2009;75:3077-85 pubmed publisher
    ..alvei CCM 2051T. ..
  38. Dickson B, Zou Y. Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol. 2010;2:a002055 pubmed publisher
    ..And for many of these axons the midline provides signals that guide them along specific lateral pathways or up and down the longitudinal axis. ..
  39. Athenstaedt K, Zweytick D, Jandrositz A, Kohlwein S, Daum G. Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol. 1999;181:6441-8 pubmed
    ..Strains with YBR177c, YMR313c, and YKL140w deleted exhibited phospholipid and/or neutral lipid patterns that were different from the wild-type strain and thus may be further candidate ORFs involved in yeast lipid metabolism. ..
  40. Jantsch Plunger V, GONCZY P, Romano A, Schnabel H, Hamill D, Schnabel R, et al. CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis. J Cell Biol. 2000;149:1391-404 pubmed
    ..Central spindle localization of CYK-4 could accelerate GTP hydrolysis by RhoA, thereby allowing contractile ring disassembly and completion of cytokinesis. ..
  41. Schindl R, Kahr H, Graz I, Groschner K, Romanin C. Store depletion-activated CaT1 currents in rat basophilic leukemia mast cells are inhibited by 2-aminoethoxydiphenyl borate. Evidence for a regulatory component that controls activation of both CaT1 and CRAC (Ca(2+) release-activated Ca(2+) channel) . J Biol Chem. 2002;277:26950-8 pubmed
    ..These results indicate that despite the difference in the permeation properties of CRAC and CaT1 channels, the latter are similarly able to form store depletion-activated conductances in RBL mast cells that are inhibited by 2-APB. ..
  42. Horkovics Kovats S, Zlatos P. Asymptotics and bioavailability in multicompartment pharmacokinetic models with enterohepatic circulation. Math Biosci. 2003;184:69-99 pubmed
    ..Finally, we apply our method to analyse and compare various pharmacokinetic models, describing the EHC of drugs, based on some previously published articles. ..
  43. Haering C, Nasmyth K. Building and breaking bridges between sister chromatids. Bioessays. 2003;25:1178-91 pubmed
    ..New research suggests that these ancient regulators of chromosome structure might function as topological devices that trap chromosomal DNA between 50 nm long coiled coils. ..
  44. Rhode S, Breuer A, Hesse J, Sonnleitner M, Pagler T, Doringer M, et al. Visualization of the uptake of individual HDL particles in living cells via the scavenger receptor class B type I. Cell Biochem Biophys. 2004;41:343-56 pubmed
    ..Costaining with organelle markers confirmed the involvement of an acidic compartment and the Golgi apparatus in the uptake process; finally, resecretion of the HDL particles was observed. ..
  45. Brännström A, Dieckmann U. Evolutionary dynamics of altruism and cheating among social amoebas. Proc Biol Sci. 2005;272:1609-16 pubmed
    ..We also demonstrate that such dimorphisms are more likely to emerge when the variation in the number of clones involved in aggregations is large. ..
  46. Panzenboeck U, Kratzer I, Sovic A, Wintersperger A, Bernhart E, Hammer A, et al. Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells. Int J Biochem Cell Biol. 2006;38:1314-29 pubmed
    ..Summarizing, in cerebrovascular endothelial cells apoA-I, ABCA1, and SR-BI represent drug targets for LXR and PPAR-agonists to interfere with cholesterol homeostasis at the periphery of the central nervous system...
  47. Pruenster M, Rot A. Throwing light on DARC. Biochem Soc Trans. 2006;34:1005-8 pubmed
    ..This limits the dissemination of chemokines through blood into distant organs and tissues as well as reducing their effects on the circulating leucocytes. ..
  48. Flaig C. Inappropriate mediastinal baroreceptor reflex as a possible cause of sudden infant death syndrome - Is thorough burping before sleep protective?. Med Hypotheses. 2007;68:1276-86 pubmed
    ..Further investigations may possibly lead to the explicit recommendation to burp all infants sufficiently and repeatedly before sleep...
  49. Rezniczek G, Konieczny P, Nikolic B, Reipert S, Schneller D, Abrahamsberg C, et al. Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan. J Cell Biol. 2007;176:965-77 pubmed
    ..It also explains the plectin phenotype observed in dystrophic skeletal muscle of mdx mice and Duchenne muscular dystrophy patients...
  50. Hartl L, Kubicek C, Seiboth B. Induction of the gal pathway and cellulase genes involves no transcriptional inducer function of the galactokinase in Hypocrea jecorina. J Biol Chem. 2007;282:18654-9 pubmed
  51. Petronczki M, Glotzer M, Kraut N, Peters J. Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev Cell. 2007;12:713-25 pubmed
    ..We propose that late mitotic Plk1 activity promotes recruitment of Ect2 to the central spindle, triggering the initiation of cytokinesis and contributing to cleavage plane specification in human cells. ..
  52. Fickert P, Stöger U, Fuchsbichler A, Moustafa T, Marschall H, Weiglein A, et al. A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis. Am J Pathol. 2007;171:525-36 pubmed
    ..This model may be valuable to investigate the mechanisms of xenobiotic-induced chronic cholangiopathies and its sequels including biliary fibrosis...
  53. Hasselblatt H, Kurzbauer R, Wilken C, Krojer T, Sawa J, Kurt J, et al. Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. Genes Dev. 2007;21:2659-70 pubmed
    ..Thus, the PDZ domain and loop L3 of DegS define a novel molecular switch allowing strict regulation of the sigmaE stress response system. ..
  54. Schmid J, Birbach A. IkappaB kinase beta (IKKbeta/IKK2/IKBKB)--a key molecule in signaling to the transcription factor NF-kappaB. Cytokine Growth Factor Rev. 2008;19:157-65 pubmed publisher
  55. Kiermayr S, Stiasny K, Heinz F. Impact of quaternary organization on the antigenic structure of the tick-borne encephalitis virus envelope glycoprotein E. J Virol. 2009;83:8482-91 pubmed publisher
    ..We have thus identified several important factors that influence the antigenicity of the flavivirus E protein and have an impact on the interaction with neutralizing antibodies. ..
  56. Mairhofer M, Steiner M, Salzer U, Prohaska R. Stomatin-like protein-1 interacts with stomatin and is targeted to late endosomes. J Biol Chem. 2009;284:29218-29 pubmed publisher
    ..This massive cholesterol accumulation clearly depends on the SCP-2 domain of SLP-1, suggesting a role for this domain in cholesterol transfer to late endosomes...
  57. Mach Aigner A, Pucher M, Mach R. D-Xylose as a repressor or inducer of xylanase expression in Hypocrea jecorina (Trichoderma reesei). Appl Environ Microbiol. 2010;76:1770-6 pubmed publisher
    ..Finally, a strain which expresses xylanase regulator 1 at a constant level was used to partially overcome the negative influence exerted by carbon catabolite repressor 1 on d-xylose. ..
  58. Loidl P. Histone acetylation: facts and questions. Chromosoma. 1994;103:441-9 pubmed
  59. Haering C, L we J, Hochwagen A, Nasmyth K. Molecular architecture of SMC proteins and the yeast cohesin complex. Mol Cell. 2002;9:773-88 pubmed
    ..The two heads of the V-shaped dimer are connected by different ends of the cleavable Scc1 subunit. Cohesin therefore forms a large proteinaceous loop within which sister chromatids might be entrapped after DNA replication...
  60. Lopato S, Forstner C, Kalyna M, Hilscher J, Langhammer U, Indrapichate K, et al. Network of interactions of a novel plant-specific Arg/Ser-rich protein, atRSZ33, with atSC35-like splicing factors. J Biol Chem. 2002;277:39989-98 pubmed
    ..However, the interacting domain is relatively small, allowing binding of additional proteins, a feature that is consistent with the proposed role of atRSZ33 in spliceosome assembly. ..
  61. Ouaked F, Rozhon W, Lecourieux D, Hirt H. A MAPK pathway mediates ethylene signaling in plants. EMBO J. 2003;22:1282-8 pubmed
    ..In contrast, ctr1 mutants showed constitutive activation of MPK6. These data indicate that a MAPK cascade is part of the ethylene signal transduction pathway in plants...
  62. Kugler G, Weiss R, Flucher B, Grabner M. Structural requirements of the dihydropyridine receptor alpha1S II-III loop for skeletal-type excitation-contraction coupling. J Biol Chem. 2004;279:4721-8 pubmed
    ..Thus, not only the primary but also the secondary structure of the critical domain is an essential determinant of the tissue-specific mode of EC coupling. ..
  63. Paumann M, Lubura B, Regelsberger G, Feichtinger M, Köllensberger G, Jakopitsch C, et al. Soluble CuA domain of cyanobacterial cytochrome c oxidase. J Biol Chem. 2004;279:10293-303 pubmed
  64. Huber I, Wappl Kornherr E, Sinnegger Brauns M, Hoda J, Walter Bastl D, Striessnig J. Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels. J Biol Chem. 2004;279:55211-7 pubmed
    ..Mutation of Thr-1066 to a non-L-type tyrosine residue can be exploited to differentially affect phenylalkylamine and dihydropyridine binding to L-type Ca(2+) channels. ..
  65. Nebauer R, Schuiki I, Kulterer B, Trajanoski Z, Daum G. The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p. FEBS J. 2007;274:6180-90 pubmed
    ..In summary, our results demonstrate a link between the mitochondrial protein import machinery, assembly and stability of Psd1p, and phosphatidylethanolamine homeostasis in yeast mitochondria. ..
  66. Brugger K, Rubel F. Simulation of climate-change scenarios to explain Usutu-virus dynamics in Austria. Prev Vet Med. 2009;88:24-31 pubmed publisher
    ..The latter depict that undetected major outbreaks before 2000 were unlikely, whereas it is likely that the USUV becomes endemic after 2040. ..
  67. Oberkofler H, Hafner M, Felder T, Krempler F, Patsch W. Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells. J Mol Med (Berl). 2009;87:299-306 pubmed publisher
    ..Our results support a role of PGC-1beta in the regulation of insulin secretion via upregulation of UCP2 and granuphilin gene expression. ..
  68. Beranek A, Rechberger G, Knauer H, Wolinski H, Kohlwein S, Leber R. Identification of a cardiolipin-specific phospholipase encoded by the gene CLD1 (YGR110W) in yeast. J Biol Chem. 2009;284:11572-8 pubmed publisher
    ..We therefore rename the Ygr110wp as Cld1p (cardiolipin-specific deacylase 1). ..
  69. Frischauf I, Muik M, Derler I, Bergsmann J, Fahrner M, Schindl R, et al. Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant. J Biol Chem. 2009;284:21696-706 pubmed publisher
  70. Sut M, Mihajlovic S, Lang S, Gruber C, Zechner E. Protein and DNA effectors control the TraI conjugative helicase of plasmid R1. J Bacteriol. 2009;191:6888-99 pubmed publisher
    ..The data support a model where protein-protein and DNA ligand interactions at the coupling protein interface coordinate the transition initiating production and uptake of the nucleoprotein secretion substrate. ..
  71. Schuller Götzburg P, Pleschberger M, Rammerstorfer F, Krenkel C. 3D-FEM and histomorphology of mandibular reconstruction with the titanium functionally dynamic bridging plate. Int J Oral Maxillofac Surg. 2009;38:1298-305 pubmed publisher
    ..Histomorphological investigations, 12 weeks and 7 years after reconstruction, show partial osseous integration or transformation of autologous iliac crest transplants...
  72. Anzola J, Sieberer T, Ortbauer M, Butt H, Korbei B, Weinhofer I, et al. Putative Arabidopsis transcriptional adaptor protein (PROPORZ1) is required to modulate histone acetylation in response to auxin. Proc Natl Acad Sci U S A. 2010;107:10308-13 pubmed publisher
    ..Collectively, our findings support a model in which translation of positional signals into developmental cues involves adjustments in chromatin modifications that orchestrate auxin effects on cell proliferation. ..
  73. Kundi M. One-hit models for virus inactivation studies. Antiviral Res. 1999;41:145-52 pubmed
    ..Designs using 10-fold dilution series, however, are generally less appropriate and also more affected by dose variability. ..
  74. Stockinger W, Brandes C, Fasching D, Hermann M, Gotthardt M, Herz J, et al. The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2. J Biol Chem. 2000;275:25625-32 pubmed
    ..This complex might participate in ApoER2-specific reelin signaling and thus would explain the different phenotype of mice lacking the ApoER2 from that of VLDLR-deficient mice. ..
  75. Buonomo S, Clyne R, Fuchs J, Loidl J, Uhlmann F, Nasmyth K. Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin. Cell. 2000;103:387-98 pubmed
    ..We show here that cleavage of Rec8 by separin at one of two different sites is necessary for the resolution of chiasmata and the disjunction of homologous chromosomes during meiosis. ..
  76. Keleman K, Rajagopalan S, Cleppien D, Teis D, Paiha K, Huber L, et al. Comm sorts robo to control axon guidance at the Drosophila midline. Cell. 2002;110:415-27 pubmed
    ..Axon traffic at the CNS midline is thus controlled by the intracellular trafficking of the Robo guidance receptor, which in turn depends on the precisely regulated expression of the Comm sorting receptor. ..
  77. Hatze H. Fundamental issues, recent advances, and future directions in myodynamics. J Electromyogr Kinesiol. 2002;12:447-54 pubmed
    ..The solutions currently obtained are highly unsatisfactory. New research directions to rectify these situations are suggested, also with regard to the identification of subject-specific myodynamic parameters. ..
  78. Eisenkolb M, Zenzmaier C, Leitner E, Schneiter R. A specific structural requirement for ergosterol in long-chain fatty acid synthesis mutants important for maintaining raft domains in yeast. Mol Biol Cell. 2002;13:4414-28 pubmed
  79. Bajari T, Strasser V, Nimpf J, Schneider W. A model for modulation of leptin activity by association with clusterin. FASEB J. 2003;17:1505-7 pubmed
    ..Thus, bioavailability of leptin at a given tissue site may be determined by the levels of clusterin and/or by the relative distribution of certain relatives of the LDL receptor vis-à-vis active leptin receptors. ..
  80. Muller E, Schwameder H. Biomechanical aspects of new techniques in alpine skiing and ski-jumping. J Sports Sci. 2003;21:679-92 pubmed
    ..and the effects of equipment, materials and individual-specific abilities on performance, safety and joint loading in ski-jumping. ..
  81. Stock C, Bozsaky E, Watzinger F, Poetschger U, Orel L, Lion T, et al. Genes proximal and distal to MYCN are highly expressed in human neuroblastoma as visualized by comparative expressed sequence hybridization. Am J Pathol. 2008;172:203-14 pubmed publisher
    ..The prognostic significance of expression peaks at 2p23.2-23.3, independent of MYCN and ALK status, remains to be investigated. ..
  82. Pauler F, Sloane M, Huang R, Regha K, Koerner M, Tamir I, et al. H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Res. 2009;19:221-33 pubmed publisher
  83. Falsone S, Kungl A, Rek A, Cappai R, Zangger K. The molecular chaperone Hsp90 modulates intermediate steps of amyloid assembly of the Parkinson-related protein alpha-synuclein. J Biol Chem. 2009;284:31190-9 pubmed publisher
    ..This suggests that Hsp90 modulates the assembly of alpha-synuclein in an ATP-dependent manner. We propose that Hsp90 affects these folding processes by restricting conformational fluctuations of alpha-synuclein. ..
  84. Plattner V, Germann B, Neuhaus W, Noe C, Gabor F, Wirth M. Characterization of two blood-brain barrier mimicking cell lines: distribution of lectin-binding sites and perspectives for drug delivery. Int J Pharm. 2010;387:34-41 pubmed publisher
    ..Cytoinvasion studies were performed with WGA for human ECV304 cells and WGA as well as DBA for PBMEC/C1-2 cells. For both lectins, the association rate to the cells was dependent on temperature which indicated cellular uptake...
  85. Wild B, Wanek W, Postl W, Richter A. Contribution of carbon fixed by Rubisco and PEPC to phloem export in the Crassulacean acid metabolism plant Kalanchoe daigremontiana. J Exp Bot. 2010;61:1375-83 pubmed publisher
    ..daigremontiana revealed that direct fixation of Rubisco during the light accounted for 30% of phloem sucrose, but only 15% of fixed carbon, indicating that carbon from direct Rubisco fixation was preferentially used for leaf export...
  86. Kren A, Mamnun Y, Bauer B, Schüller C, Wolfger H, Hatzixanthis K, et al. War1p, a novel transcription factor controlling weak acid stress response in yeast. Mol Cell Biol. 2003;23:1775-85 pubmed
    ..In turn, War1p activation is necessary for the induction of PDR12 through a novel signal transduction event that elicits weak organic acid stress adaptation...
  87. Birner R, Nebauer R, Schneiter R, Daum G. Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine biosynthetic machinery with the prohibitin complex of Saccharomyces cerevisiae. Mol Biol Cell. 2003;14:370-83 pubmed
    ..In conclusion, destabilizing effects triggered by low levels of mitochondrial PtdEtn seem to account for synthetic lethality of psd1Delta with phb mutants. ..
  88. Wu Q, Boenigk J, Hahn M. Successful predation of filamentous bacteria by a nanoflagellate challenges current models of flagellate bacterivory. Appl Environ Microbiol. 2004;70:332-9 pubmed
  89. Pelster B. pH regulation and swimbladder function in fish. Respir Physiol Neurobiol. 2004;144:179-90 pubmed
    ..The mechanisms regulating the activity of these acid-secreting pathways and of the metabolism responsible for the production of protons are largely unknown...
  90. Konieczny P, Fuchs P, Reipert S, Kunz W, Zeöld A, Fischer I, et al. Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms. J Cell Biol. 2008;181:667-81 pubmed publisher
    ..Our findings establish plectin as the major organizer of desmin IFs in myofibers and provide new insights into plectin- and desmin-related muscular dystrophies. ..
  91. Wolinski H, Petrovic U, Mattiazzi M, Petschnigg J, Heise B, Natter K, et al. Imaging-based live cell yeast screen identifies novel factors involved in peroxisome assembly. J Proteome Res. 2009;8:20-7 pubmed publisher
  92. Derler I, Fahrner M, Muik M, Lackner B, Schindl R, Groschner K, et al. A Ca2(+ )release-activated Ca2(+) (CRAC) modulatory domain (CMD) within STIM1 mediates fast Ca2(+)-dependent inactivation of ORAI1 channels. J Biol Chem. 2009;284:24933-8 pubmed publisher
    ..In summary, CMD within the STIM1 cytosolic part provides a negative feedback signal to Ca(2+) entry by triggering fast Ca(2+)-dependent inactivation of ORAI/CRAC channels. ..