Experts and Doctors on biliary atresia in United States
Locale: United States
Topic: biliary atresia
Lane W, Zanol K. Duodenal atresia, biliary atresia, and intestinal infarct in truncal aplasia cutis congenita. Pediatr Dermatol. 2000;17:290-2 pubmed
..While the association of duodenal atresia with aplasia cutis congenita has been described, the findings of biliary atresia and midgut atresia in association with aplasia cutis congenita have not been described previously. ..
Wang P, Xun P, He K, Cai W. Comparison of liver transplantation outcomes in biliary atresia patients with and without prior portoenterostomy: A meta-analysis. Dig Liver Dis. 2016;48:347-52 pubmed publisher
..02). Accumulated literature suggested that a prior portoenterostomy did not adversely affect outcomes of liver transplantation in children with biliary atresia. ..
Lu B, Brindley S, Tucker R, Lambert C, Mack C. ?-enolase autoantibodies cross-reactive to viral proteins in a mouse model of biliary atresia. Gastroenterology. 2010;139:1753-61 pubmed publisher
..We aimed to identify autoantigens recognized by serum antibodies in the Rhesus rotavirus (RRV)-induced mouse model of BA; findings were correlated with BA in humans...
Mack C, Feldman A, Sokol R. Clues to the etiology of bile duct injury in biliary atresia. Semin Liver Dis. 2012;32:307-16 pubmed publisher
..What controls the coordination of these events, why the disease only occurs in the first few months of life, and why a minority of infants with perinatal viral infections develop BA are remaining questions to be answered...
Feldman A, Tucker R, Fenner E, Pelanda R, Mack C. B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia. PLoS ONE. 2013;8:e73644 pubmed publisher
..The mechanism of protection may involve lack of B cell antigen presentation, which impairs T-cell activation and Th1 inflammation. Immune modulators that inhibit B cell function may be a new strategy for treatment of BA. ..