Experts and Doctors on basic leucine zipper transcription factors in United States
Locale: United States
Topic: basic leucine zipper transcription factors
Nominé Y, Botuyan M, Bajzer Z, Owen W, Caride A, Wasielewski E, et al
. Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations. Biochemistry. 2008;47:9866-79 pubmed publisher
..The dynamic nature of BRCA1-BRCT may facilitate the binding of BRCA1 to different phosphorylated protein targets. ..
Beaver L, Hooven L, Butcher S, Krishnan N, Sherman K, Chow E, et al
. Circadian clock regulates response to pesticides in Drosophila via conserved Pdp1 pathway. Toxicol Sci. 2010;115:513-20 pubmed publisher
..Taken together, our data uncover a pathway from the positive arm of the circadian clock through Pdp1 to detoxification effector genes, demonstrating a conserved role of the circadian system in modulating xenobiotic toxicity. ..
Kunchithapautham K, Coughlin B, Crouch R, Rohrer B. Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement. Invest Ophthalmol Vis Sci. 2009;50:4858-64 pubmed publisher
..Here, we determine the consequences of 11-cis retinal withdrawal and supplementation on cone development in the all-cone Nrl(-/-) retina...
Wu C, Roje S, Sandoval F, Bird A, Winge D, Eide D. Repression of sulfate assimilation is an adaptive response of yeast to the oxidative stress of zinc deficiency. J Biol Chem. 2009;284:27544-56 pubmed publisher
..These studies have led to new insights into how cells adapt to nutrient-limiting growth conditions. ..
Kang S, Price J, Lin P, Hong J, Jang J. The arabidopsis bZIP1 transcription factor is involved in sugar signaling, protein networking, and DNA binding. Mol Plant. 2010;3:361-73 pubmed publisher
..Finally, we show that AtbZIP1 can bind ACGT-based motifs in vitro and that the binding characteristics appear to be affected by the heterodimerization between AtbZIP1 and the C-group AtbZIPs, including AtbZIP10 and AtbZIP63. ..
Qin Z, Freitas E, Sullivan R, Mohan S, Bacelieri R, Branch D, et al
. Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress. PLoS Pathog. 2010;6:e1000742 pubmed publisher
..Collectively, these data support a role for KSHV itself in promoting de novo KSHV infection and the survival of KSHV-infected, RNS-secreting cells in the tumor microenvironment through the induction of xCT. ..
Watanabe R, Murai M, Singh C, Fox S, Ii M, Asano K. The eukaryotic initiation factor (eIF) 4G HEAT domain promotes translation re-initiation in yeast both dependent on and independent of eIF4A mRNA helicase. J Biol Chem. 2010;285:21922-33 pubmed publisher
..Based on the RNA-binding activities identified within the unstructured segments flanking the eIF4G2 HEAT domain, we discuss the role of the HEAT domain in scanning beyond loading eIF4A onto the pre-initiation complex. ..
Riewe S, Mans J, Hirano T, Katz J, Shiverick K, Brown T, et al
. Human trophoblast responses to Porphyromonas gingivalis infection. Mol Oral Microbiol. 2010;25:252-9 pubmed publisher
..Hence, infection of trophoblasts by P. gingivalis can impact signal transduction pathways and modulate cytokine expression, outcomes that could disrupt the maintenance of pregnancy. ..
Chen C, Blakeley L, Koutalos Y. Formation of all-trans retinol after visual pigment bleaching in mouse photoreceptors. Invest Ophthalmol Vis Sci. 2009;50:3589-95 pubmed publisher
..Different types of photoreceptors contain a comparable fraction of reduced NADPH to drive the reduction of all-trans retinal. ..