Experts and Doctors on base sequence in Sweden

Summary

Locale: Sweden
Topic: base sequence

Top Publications

  1. Larsson S, Nilvebrant N, Jönsson L. Effect of overexpression of Saccharomyces cerevisiae Pad1p on the resistance to phenylacrylic acids and lignocellulose hydrolysates under aerobic and oxygen-limited conditions. Appl Microbiol Biotechnol. 2001;57:167-74 pubmed
    ..The Pad1p overexpressing transformants also showed a 22-25% faster glucose consumption rate, a 40-45% faster mannose consumption rate, and a 24-29% faster ethanol production rate in the dilute acid hydrolysate of spruce. ..
  2. Patrone C, Cassel T, Pettersson K, Piao Y, Cheng G, Ciana P, et al. Regulation of postnatal lung development and homeostasis by estrogen receptor beta. Mol Cell Biol. 2003;23:8542-52 pubmed
    ..These results provide a potential molecular mechanism for the gender differences in alveolar structure observed in the adult lung and establish ERbeta as a previously unknown regulator of postnatal lung development and homeostasis. ..
  3. Gardmo C, Mode A. In vivo transfection of rat liver discloses binding sites conveying GH-dependent and female-specific gene expression. J Mol Endocrinol. 2006;37:433-41 pubmed
    ..Based on our present results, we propose that adjacent binding sites for NF1 and HNF6 constitute a gene regulatory unit of importance for transducing the female-specific effect of GH in rat liver. ..
  4. Barsoum E, Martinez P, Aström S. Alpha3, a transposable element that promotes host sexual reproduction. Genes Dev. 2010;24:33-44 pubmed publisher
    ..This study provides empirical evidence for selfish DNA promoting host sexual reproduction by mediating mating type switch. ..
  5. Holmberg C, Rutberg B. Expression of the gene encoding glycerol-3-phosphate dehydrogenase (glpD) in Bacillus subtilis is controlled by antitermination. Mol Microbiol. 1991;5:2891-900 pubmed
    ..The inverted repeat appears to be a target for induction by G3P and GlpP. We speculate that glucose repression is mediated via an inhibitory effect on synthesis or activity of GlpP. ..
  6. Claesson C, Samuelsson T, Lustig F, Boren T. Codon reading properties of an unmodified transfer RNA. FEBS Lett. 1990;273:173-6 pubmed
  7. Holmdahl R, Karlsson M, Andersson M, Rask L, Andersson L. Localization of a critical restriction site on the I-A beta chain that determines susceptibility to collagen-induced arthritis in mice. Proc Natl Acad Sci U S A. 1989;86:9475-9 pubmed
  8. Gershagen S, Lundwall A, Fernlund P. Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis. Nucleic Acids Res. 1989;17:9245-58 pubmed
    ..From the primary structure of this putative SHBG-gene-related protein, it may be deduced that it is a protein very different from SHBG and probably without steroid binding activity. ..
  9. Enerback S, Bjursell G. Genomic organization of the region encoding guinea pig lipoprotein lipase; evidence for exon fusion and unconventional splicing. Gene. 1989;84:391-7 pubmed

More Information

Publications345 found, 100 shown here

  1. Nilsson O, Aberg A, Lundqvist T, Sjoberg B. Nucleotide sequence of the gene coding for the large subunit of ribonucleotide reductase of Escherichia coli. Correction. Nucleic Acids Res. 1988;16:4174 pubmed
  2. Durbeej M, Larsson E, Ibraghimov Beskrovnaya O, Roberds S, Campbell K, Ekblom P. Non-muscle alpha-dystroglycan is involved in epithelial development. J Cell Biol. 1995;130:79-91 pubmed
    ..We suggest that the dystroglycan complex acts as a receptor for basement membrane components during epithelial morphogenesis. It is likely that this involves binding of alpha-dystroglycan to E3 fragment of laminin-1. ..
  3. Lundin M, Nehlin J, Ronne H. Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1. Mol Cell Biol. 1994;14:1979-85 pubmed
    ..We conclude that DNA binding by a simple zinc finger protein such as MIG1 can involve both recognition of the GC box and flanking sequence preferences that may reflect local DNA bendability. ..
  4. Persson B, Björk G. Isolation of the gene (miaE) encoding the hydroxylase involved in the synthesis of 2-methylthio-cis-ribozeatin in tRNA of Salmonella typhimurium and characterization of mutants. J Bacteriol. 1993;175:7776-85 pubmed
    ..Unexpectedly, such mutants cannot utilize the citric acid cycle intermediates malate, fumarate, and succinate as carbon sources. ..
  5. Owman C, Lolait S, Santen S, Olde B. Molecular cloning and tissue distribution of cDNA encoding a novel chemoattractant-like receptor. Biochem Biophys Res Commun. 1997;241:390-4 pubmed
    ..Another larger RNA species of 6.3 kb appeared in heart and lung. In situ hybridization histochemistry performed on tissue from liver and kidney revealed a mainly vascular distribution of the receptor message. ..
  6. Svensson S, Stromberg P, Hoog J. A novel subtype of class II alcohol dehydrogenase in rodents. Unique Pro(47) and Ser(182) modulates hydride transfer in the mouse enzyme. J Biol Chem. 1999;274:29712-9 pubmed
    ..All these data indicate that the mammalian class II alcohol dehydrogenase line is divided into two structurally and functionally distinct subgroups. ..
  7. Tegmark K, Karlsson A, Arvidson S. Identification and characterization of SarH1, a new global regulator of virulence gene expression in Staphylococcus aureus. Mol Microbiol. 2000;37:398-409 pubmed
    ..In conclusion, we show that both the agr-dependent suppression of protein A production and the sarA-dependent stimulation of alpha-toxin production is mediated via a new regulator, SarH1, which belongs to a family of Sar homologues...
  8. Rylander T, Neve E, Ingelman Sundberg M, Oscarson M. Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1). Biochem Biophys Res Commun. 2001;281:529-35 pubmed
    ..We conclude that CYP2S1 represents a novel abundantly expressed human P450 with potential importance for extrahepatic xenobiotic metabolism. ..
  9. Larsson S, Nygard O. Proposed secondary structure of eukaryote specific expansion segment 15 in 28S rRNA from mice, rats, and rabbits. Biochemistry. 2001;40:3222-31 pubmed
  10. Fioretos T, Panagopoulos I, Lassen C, Swedin A, Billström R, Isaksson M, et al. Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL. Genes Chromosomes Cancer. 2001;32:302-10 pubmed
  11. Dizeyi N, Konrad L, Bjartell A, Wu H, Gadaleanu V, Hansson J, et al. Localization and mRNA expression of somatostatin receptor subtypes in human prostatic tissue and prostate cancer cell lines. Urol Oncol. 2002;7:91-8 pubmed
  12. Hegelund T, Celander M. Hepatic versus extrahepatic expression of CYP3A30 and CYP3A56 in adult killifish (Fundulus heteroclitus). Aquat Toxicol. 2003;64:277-91 pubmed
    ..Moreover, CYP3A expression also is evident in brain and ovary in killifish, which suggests a role for CYP3A enzymes in biotransformation of xenobiotics and fine-tuning levels of steroid hormones in situ in extrahepatic organs...
  13. Hellqvist A, Bornestaf C, Borg B, Schmitz M. Cloning and sequencing of the FSH-beta and LH beta-subunit in the three-spined stickleback, Gasterosteus aculeatus, and effects of photoperiod and temperature on LH-beta and FSH-beta mRNA expression. Gen Comp Endocrinol. 2004;135:167-74 pubmed
    ..Thus, both GTHs displayed their lowest expression when spermatogenesis was active and when low KEH indicated that androgens levels were at their lowest. ..
  14. Nilsson R, Larsson K, Larsson E, Kõljalg U. Fruiting body-guided molecular identification of root-tip mantle mycelia provides strong indications of ectomycorrhizal associations in two species of Sistotrema (Basidiomycota). Mycol Res. 2006;110:1426-32 pubmed
    ..The cantharelloid clade contains several mycorrhizal genera, but no symbiotic associations have previously been demonstrated for Sistotrema. ..
  15. Belikov S, Astrand C, Wrange O. Mechanism of histone H1-stimulated glucocorticoid receptor DNA binding in vivo. Mol Cell Biol. 2007;27:2398-410 pubmed
    ..These effects results in increased concentration of free GR and, hence, in increased GR-GRE binding...
  16. Valtonen Andre C, Bjartell A, Hellsten R, Lilja H, Härkönen P, Lundwall A. A highly conserved protein secreted by the prostate cancer cell line PC-3 is expressed in benign and malignant prostate tissue. Biol Chem. 2007;388:289-95 pubmed
    ..Studies on human prostate cancer specimens showed immunohistochemical staining of both tumor and benign glandular cells. Our results suggest that PSMP is an important protein with significance in prostate cancer. ..
  17. Chen H, Sun S, Sundberg P, Ren W, Norenburg J. A comparative study of nemertean complete mitochondrial genomes, including two new ones for Nectonemertes cf. mirabilis and Zygeupolia rubens, may elucidate the fundamental pattern for the phylum Nemertea. BMC Genomics. 2012;13:139 pubmed publisher
    ..Phylogenetic analysis proposes a sister-group relationship between Hetero- and Hoplonemertea, which supports one of two recent alternative hypotheses of nemertean phylogeny. ..
  18. Ulvsback M, Spurr N, Lundwall A. Assignment of the human gene for beta-microseminoprotein (MSMB) to chromosome 10 and demonstration of related genes in other vertebrates. Genomics. 1991;11:920-4 pubmed
    ..A related gene might be present in other mammals, birds, and amphibians as revealed by DNA hybridization under conditions of low stringency. ..
  19. Aberg A, Hahne S, Karlsson M, Larsson A, Ormo M, Ahgren A, et al. Evidence for two different classes of redox-active cysteines in ribonucleotide reductase of Escherichia coli. J Biol Chem. 1989;264:12249-52 pubmed
    ..coli ribonucleotide reductase suggested previously (Lin, A.-N. I., Ashley, G. W., and Stubbe, J. (1987) Biochemistry 26, 6905-6909). ..
  20. Gearing K, Crickmore A, Gustafsson J. Structure of the mouse peroxisome proliferator activated receptor alpha gene. Biochem Biophys Res Commun. 1994;199:255-63 pubmed
    ..The 5' flanking region is GC rich and contains several putative SP1 binding sites. The structure of the PPAR alpha gene is unique but shares similar features with related members of the nuclear hormone receptor family. ..
  21. Liu Y, Haggård Ljungquist E. Functional characterization of the P2 A initiator protein and its DNA cleavage site. Virology. 1996;216:158-64 pubmed
  22. Xu X, Arnason U. A complete sequence of the mitochondrial genome of the western lowland gorilla. Mol Biol Evol. 1996;13:691-8 pubmed publisher
    ..The analysis of the peptide-coding genes suggest that relative to comparison between Homo and Pan a certain degree of transition saturation has taken place in codon position 3 in comparisons between Gorilla to either Homo or Pan...
  23. Bergström T, Josefsson A, Erlich H, Gyllensten U. Recent origin of HLA-DRB1 alleles and implications for human evolution. Nat Genet. 1998;18:237-42 pubmed
  24. Ejeskär K, Abel F, Sjoberg R, Backstrom J, Kogner P, Martinsson T. Fine mapping of the human preprocortistatin gene (CORT) to neuroblastoma consensus deletion region 1p36.3-->p36.2, but absence of mutations in primary tumors. Cytogenet Cell Genet. 2000;89:62-6 pubmed
    ..Through genomic sequencing we made mutation analyses of exonic sequences in 49 primary neuroblastomas of all different stages, but no mutations could be detected. ..
  25. Bylund J, Bylund M, Oliw E. cDna cloning and expression of CYP4F12, a novel human cytochrome P450. Biochem Biophys Res Commun. 2001;280:892-7 pubmed
    ..Several CYP4F enzymes are important omega 1- and omega 2-hydroxylases of eicosanoids. The physiological function of CYP4F12 merits further investigation. ..
  26. Noppa L, Ostberg Y, Lavrinovicha M, Bergstr m S. P13, an integral membrane protein of Borrelia burgdorferi, is C-terminally processed and contains surface-exposed domains. Infect Immun. 2001;69:3323-34 pubmed publisher
    ..The size of the p13 transcript was consistent with a monocistronic transcript. This new gene family may be involved in functions that are specific for this spirochete and its pathogenesis...
  27. Asadi A, Jörgensen J, Jacobsson A. Elovl1 and p55Cdc genes are localized in a tail-to-tail array and are co-expressed in proliferating cells. J Biol Chem. 2002;277:18494-500 pubmed
  28. Domkin V, Thelander L, Chabes A. Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex. J Biol Chem. 2002;277:18574-8 pubmed
    ..In complex with inactive Rnr1-C428A, the activity of Rnr3 is controlled by effector binding to Rnr1-C428A. This result indicates cross-talk between the Rnr1 and Rnr3 polypeptides of the large subunit. ..
  29. Nourizad N, Ehn M, Gharizadeh B, Hober S, Nyrén P. Methylotrophic yeast Pichia pastoris as a host for production of ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum). Protein Expr Purif. 2003;27:229-37 pubmed
    ..By enzymatic removal of N-glycans, a single band corresponding to a molecular mass of 48kDa was detected. The recombinant apyrase was found to function well when it was used in combination with the Pyrosequencing technology. ..
  30. Johansson E, Niklasson B, Tesh R, Shafren D, Travassos da Rosa A, Lindberg A. Molecular characterization of M1146, an American isolate of Ljungan virus (LV) reveals the presence of a new LV genotype. J Gen Virol. 2003;84:837-44 pubmed
    ..Genetic and phylogenetic analyses show that M1146 represents a new genotype within the distinct LV cluster. Isolation of LV from both Swedish and American voles trapped over a period of 30 years suggests a continuous worldwide presence. ..
  31. Alheim K, Corness J, Samuelsson M, Bladh L, Murata T, Nilsson T, et al. Identification of a functional glucocorticoid response element in the promoter of the cyclin-dependent kinase inhibitor p57Kip2. J Mol Endocrinol. 2003;30:359-68 pubmed
    ..All these data emphasize the involvement of this GRE in the glucocorticoid-mediated induction of p57(Kip2) expression. ..
  32. Xu L, Pan Hammarstrom Q, Forsti A, Hemminki K, Hammarstrom L, Labuda D, et al. Human estrogen receptor beta 548 is not a common variant in three distinct populations. Endocrinology. 2003;144:3541-6 pubmed
    ..We did not detect any alleles that correspond to hERbeta548 in these samples or in additional samples of heterogeneous origin. It is concluded that hERbeta548 is not a common variant in Africans, Caucasians, or Asians. ..
  33. Westberg J, Persson A, Holmberg A, Goesmann A, Lundeberg J, Johansson K, et al. The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP). Genome Res. 2004;14:221-7 pubmed
  34. Andersson I, Bladh L, Mousavi Jazi M, Magnusson K, Lundkvist A, Haller O, et al. Human MxA protein inhibits the replication of Crimean-Congo hemorrhagic fever virus. J Virol. 2004;78:4323-9 pubmed
    ..These results suggest that MxA, by interacting with a component of the nucleocapsid, prevents replication of CCHFV viral RNA and thereby inhibits the production of new infectious virus particles. ..
  35. Aspholm Hurtig M, Dailide G, Lahmann M, Kalia A, Ilver D, Roche N, et al. Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science. 2004;305:519-22 pubmed
  36. Paulsson J, Westermark G. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005;54:2117-25 pubmed
    ..When extracellularly exposed, this amyloid might act as template for continuing amyloid formation from processed IAPP released from the surrounding beta-cells. ..
  37. Gonzalez de Valdivia E, Isaksson L. Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA. FEBS J. 2005;272:5306-16 pubmed
    ..This does not happen if these codons are located further down in the mRNA at position +7, or later. ..
  38. Polakova S, Blume C, Zárate J, Mentel M, Jørck Ramberg D, Stenderup J, et al. Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata. Proc Natl Acad Sci U S A. 2009;106:2688-93 pubmed publisher
    ..We show that the observed genome plasticity is connected with antifungal drug resistance and it is likely an advantage in the human body, where environmental conditions fluctuate a lot. ..
  39. Holmqvist M, Stensjö K, Oliveira P, Lindberg P, Lindblad P. Characterization of the hupSL promoter activity in Nostoc punctiforme ATCC 29133. BMC Microbiol. 2009;9:54 pubmed publisher
    ..To further investigate the hupSL promoter, truncated versions of the hupSL promoter were fused to either gfp or luxAB, encoding the reporter proteins Green Fluorescent Protein and Luciferase, respectively...
  40. Kollberg G, Tulinius M, Melberg A, Darin N, Andersen O, Holmgren D, et al. Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy. Brain. 2009;132:2170-9 pubmed publisher
    ..There was only a slight reduction of mitochondrial IscU in the compound heterozygotes, despite their severe phenotype, indicating that the IscU expressed in these patients is non-functional...
  41. Ng uni D, Geleta M, Fatih M, Bryngelsson T. Phylogenetic analysis of the genus Sorghum based on combined sequence data from cpDNA regions and ITS generate well-supported trees with two major lineages. Ann Bot. 2010;105:471-80 pubmed publisher
    ..S. bicolor-3, -11 and -14, from southern Africa, are closely related to each other but distantly related to S. bicolor-2. ..
  42. Geli J, Kiss N, Kogner P, Larsson C. Suppression of RIZ in biologically unfavourable neuroblastomas. Int J Oncol. 2010;37:1323-30 pubmed
    ..005). Suppression of RIZ1 is likely to contribute to the pathogenesis of biologically unfavourable neuroblastomas. In contrast to multiple other neoplasias, RIZ1 promoter methylation is not a common event in neuroblastoma. ..
  43. Blomqvist A, Roubos E, Larhammar D, Martens G. Cloning and sequence analysis of a neuropeptide Y/peptide YY receptor Y1 cDNA from Xenopus laevis. Biochim Biophys Acta. 1995;1261:439-41 pubmed
    ..The intracellular regions including the carboxy-terminal tail are nearly identical between Xenopus and mammals, suggesting strong structural constraints on the portions that may interact with G proteins. ..
  44. Olsen H, Hedengran Faulds M, Saharinen P, Silvennoinen O, Haldosén L. Effects of hyperactive Janus kinase 2 signaling in mammary epithelial cells. Biochem Biophys Res Commun. 2002;296:139-44 pubmed
    ..Proliferation was not affected by any of the mutants whereas the ability to undergo apoptosis was decreased implicating a transforming potential of the JAK2 mutants. ..
  45. Qi D, Larsson J, Mannervik M. Drosophila Ada2b is required for viability and normal histone H3 acetylation. Mol Cell Biol. 2004;24:8080-9 pubmed
    ..This could be an evolutionarily conserved function, since a yeast ada2 mutant is also sensitive to a genotoxic agent. ..
  46. Jacobsson S, Hedberg S, Mölling P, Unemo M, Comanducci M, Rappuoli R, et al. Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease. Vaccine. 2009;27:1579-84 pubmed publisher
    ..GNA2132 (54% of the amino acids conserved) appeared to be the most diversified antigen. Consequently, the theoretical coverage of the 5CVMB antigens and the feasibility to use these in a broad-range meningococcal vaccine is appealing. ..
  47. Ferletta M, Caglayan D, Mokvist L, Jiang Y, Kastemar M, Uhrbom L, et al. Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells. Int J Cancer. 2011;129:45-60 pubmed publisher
    ..We suggest that Sox21 can negatively regulate Sox2 in glioma. Our findings imply that Sox2 and Sox21 may be interesting targets for the development of novel glioma therapy. ..
  48. Khan W, Hammarstrom S. Identification of a new carcinoembryonic antigen (CEA) family member in human fetal liver--cloning and sequence determination of pregnancy-specific glycoprotein 7. Biochem Biophys Res Commun. 1990;168:214-25 pubmed
    ..The function of PSGs is probably linked to the N-domain and the CDR2- and CD3-like regions are most likely responsible for ligand binding. ..
  49. Liljestrom P, Laamanen I, Palva E. Structure and expression of the ompB operon, the regulatory locus for the outer membrane porin regulon in Salmonella typhimurium LT-2. J Mol Biol. 1988;201:663-73 pubmed
    ..Hence, the tightly coupled synthesis of these proteins seems to be essential in eliciting a proper response in the transmembrane regulation of gene expression. ..
  50. Jordan A, Pontis E, Aslund F, Hellman U, Gibert I, Reichard P. The ribonucleotide reductase system of Lactococcus lactis. Characterization of an NrdEF enzyme and a new electron transport protein. J Biol Chem. 1996;271:8779-85 pubmed
    ..The NrdEF enzymes use NrdH proteins as electron transporter in place of thioredoxin or glutaredoxin used by NrdAB enzymes. The two classes also differ in their allosteric regulation by dATP...
  51. Båtshake B, Sundelin J. The mouse genes for the EP1 prostanoid receptor and the PKN protein kinase overlap. Biochem Biophys Res Commun. 1996;227:70-6 pubmed
    ..The 3' part of the PKN gene is highly fragmented and its intron/exon organisation is reminiscent of that of the Drosophila protein kinase C gene. The possibility of a natural antisense regulation of these genes is discussed. ..
  52. Johansson M, Karlsson A. Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2. J Biol Chem. 1997;272:8454-8 pubmed
    ..At the time of this report all four of the known human deoxyribonucleoside kinases have been cloned. This provides the opportunity to characterize their individual contribution to therapeutic and toxic effects of nucleoside analogs. ..
  53. Knutson A, Hellman P, Akerstrom G, Westin G. Characterization of the human Megalin/LRP-2 promoter in vitro and in primary parathyroid cells. DNA Cell Biol. 1998;17:551-60 pubmed
  54. Owman C, Garzino Demo A, Cocchi F, Popovic M, Sabirsh A, Gallo R. The leukotriene B4 receptor functions as a novel type of coreceptor mediating entry of primary HIV-1 isolates into CD4-positive cells. Proc Natl Acad Sci U S A. 1998;95:9530-4 pubmed
    ..BLTR belongs to the same general chemoattractant receptor family as the chemokine receptors but is structurally more distant from them than are any of the previously described HIV-1 coreceptors. ..
  55. Akerblad P, Rosberg M, Leanderson T, Sigvardsson M. The B29 (immunoglobulin beta-chain) gene is a genetic target for early B-cell factor. Mol Cell Biol. 1999;19:392-401 pubmed
    ..These data suggest that the B29 gene is a genetic target for EBF in early B-cell development. ..
  56. Englund C, Uv A, Cantera R, Mathies L, Krasnow M, Samakovlis C. adrift, a novel bnl-induced Drosophila gene, required for tracheal pathfinding into the CNS. Development. 1999;126:1505-14 pubmed
  57. Beatus P, Lundkvist J, Oberg C, Lendahl U. The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters. Development. 1999;126:3925-35 pubmed
    ..In conclusion, this is the first example of a Notch IC that functions as a repressor in Enhancer of Split/HES upregulation, and shows that mammalian Notch receptors have acquired distinct functions during evolution. ..
  58. Poorafshar M, Aveskogh M, Munday B, Hellman L. Identification and structural analysis of four serine proteases in a monotreme, the platypus, Ornithorhynchus anatinus. Immunogenetics. 2000;52:19-28 pubmed
    ..This latter finding indicates a higher evolutionary pressure to maintain specific functions in the complement and coagulation enzymes compared to many of the hematopoietic serine proteases. ..
  59. Panagopoulos I, Möller E, Isaksson M, Mertens F. A PCR/restriction digestion assay for the detection of the transcript variants 1 and 2 of POU5F1. Genes Chromosomes Cancer. 2008;47:521-9 pubmed publisher
    ..This trace amount of DNA is a source of false positive RT-PCR amplifications. This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat. ..
  60. Matsumoto T, Schiller P, Dieterich L, Bahram F, Iribe Y, Hellman U, et al. Ninein is expressed in the cytoplasm of angiogenic tip-cells and regulates tubular morphogenesis of endothelial cells. Arterioscler Thromb Vasc Biol. 2008;28:2123-30 pubmed publisher
    ..These data strongly implicate ninein as an important new regulator of angiogenesis. ..
  61. Monstein H, Tärnberg M, Nilsson L. Molecular identification of CTX-M and blaOXY/K1 beta-lactamase genes in Enterobacteriaceae by sequencing of universal M13-sequence tagged PCR-amplicons. BMC Infect Dis. 2009;9:7 pubmed publisher
    ..The principles used in this study could also be applied to any situation in which antimicrobial resistance genes would need to be sequenced. ..
  62. Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana F, et al. Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway. J Exp Med. 2009;206:1661-71 pubmed publisher
  63. Jonas K, Edwards A, Ahmad I, Romeo T, Romling U, Melefors O. Complex regulatory network encompassing the Csr, c-di-GMP and motility systems of Salmonella Typhimurium. Environ Microbiol. 2010;12:524-40 pubmed publisher
    ..Altogether, our data reveal that the concerted and complex regulation of several genes encoding GGDEF/EAL domain proteins allows CsrA to control the motility-sessility switch in S. Typhimurium at multiple levels. ..
  64. Ottosson E, Kubartová A, Edman M, Jönsson M, Lindhe A, Stenlid J, et al. Diverse ecological roles within fungal communities in decomposing logs of Picea abies. FEMS Microbiol Ecol. 2015;91: pubmed publisher
    ..Combining taxonomic identification with knowledge of ecological roles may provide valuable insights into properties of fungal communities; however, precise ecological information about many fungal species is still lacking. ..
  65. Lerche M, Dian C, Round A, Lönneborg R, Brzezinski P, Leonard G. The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors. Sci Rep. 2016;6:19988 pubmed publisher
    ..Our results thus provide clear evidence at the molecular level which strongly supports the 'sliding dimer' hypothesis concerning LTTR activation mechanisms. ..
  66. Larhammar D, Blomqvist A, Yee F, Jazin E, Yoo H, Wahlested C. Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type. J Biol Chem. 1992;267:10935-8 pubmed
  67. Wikström P, Lind L, Berg D, Björk G. Importance of mRNA folding and start codon accessibility in the expression of genes in a ribosomal protein operon of Escherichia coli. J Mol Biol. 1992;224:949-66 pubmed
    ..Possibly, the two mRNA secondary structures function to decouple translation of 21K and trmD from that of the respective upstream cistron in order to achieve their independent regulation. ..
  68. Rimpil inen M, Forsberg A, Wolf Watz H. A novel protein, LcrQ, involved in the low-calcium response of Yersinia pseudotuberculosis shows extensive homology to YopH. J Bacteriol. 1992;174:3355-63 pubmed
    ..The LcrQ protein was recovered from the culture supernatant. LcrQ shows 42% identity to the first 128 amino acids of the YopH virulence protein...
  69. Thelander M, Thelander L. Molecular cloning and expression of the functional gene encoding the M2 subunit of mouse ribonucleotide reductase: a new dominant marker gene. EMBO J. 1989;8:2475-9 pubmed
    ..M2 genomic DNA should be a valuable dominant, selectable marker for identifying and isolating stable co-transformants. ..
  70. Kondo K, Kai M, Setoguchi Y, Eggertsen G, Sjoblom P, Setoguchi T, et al. Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme. Eur J Biochem. 1994;219:357-63 pubmed
    ..The substrate specificity of the human enzyme is considerably narrower than that of the rat enzyme, and the enzyme seems to be more important for bile acid biosynthesis than for metabolism of steroid hormones. ..
  71. Noppa L, Burman N, Sadziene A, Barbour A, Bergstr m S. Expression of the flagellin gene in Borrelia is controlled by an alternative sigma factor. Microbiology. 1995;141 ( Pt 1):85-93 pubmed publisher
    ..Instead, the promoter of the fla gene in Borrelia has most similarity to the bacteriophage SP01 sigma gp33-34 promoter sequence of Bacillus subtilis...
  72. Hultmark D. Immune reactions in Drosophila and other insects: a model for innate immunity. Trends Genet. 1993;9:178-83 pubmed
    ..The induction of this system, which lacks clonally selected receptors like those of vertebrate B and T cells, may provide a model for innate immune reactions in other animals, including vertebrates. ..
  73. Farewell A, Diez A, DiRusso C, Nystr m T. Role of the Escherichia coli FadR regulator in stasis survival and growth phase-dependent expression of the uspA, fad, and fab genes. J Bacteriol. 1996;178:6443-50 pubmed
    ..In addition, cells carrying fadRS219N survive long-term stasis poorly, indicating that FadR-dependent alterations in fatty acid metabolism are an integral and important part of the adaptation to stationary phase...
  74. Samuelsson T, Macao B, B lske G. A 13-kDa protein with a helix-turn-helix motif is encoded by bacterial operons related to the SRP pathway. Biochem Biophys Res Commun. 1997;231:839-43 pubmed publisher
    ..Sequence analysis of the p13 proteins strongly suggest that they have a helix-turn-helix (HTH) motif, indicating that they are gene regulatory proteins...
  75. Larsson P, Claesson H, Kennedy B. Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity. J Biol Chem. 1998;273:207-14 pubmed
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