Experts and Doctors on bacterial proteins in United States

Summary

Locale: United States
Topic: bacterial proteins

Top Publications

  1. Gerber M, Caparas L, Randolph M. Evaluation of a new latex agglutination test for detection of streptolysin O antibodies. J Clin Microbiol. 1990;28:413-5 pubmed
  2. Grbic M, Nagy L, Carroll S, Strand M. Polyembryonic development: insect pattern formation in a cellularized environment. Development. 1996;122:795-804 pubmed
    ..We also observe that the expression of these regulatory proteins does not occur during the early proliferative phases of polyembryony. Our results indicate that a syncytium is not required for segmental patterning in this insect. ..
  3. Miyamoto M, Fitch W. Constraints on protein evolution and the age of the eubacteria/eukaryote split. Syst Biol. 1996;45:568-75 pubmed
    ..The authors conclude that their research supports the range of dates for the cenancestor of modern eubacteria, archaebacteria, and eukaryotes estimated by Doolittle et al. ..
  4. Springs S, Diavolitsis V, Goodhouse J, McLendon G. The kinetics of translocation of Smac/DIABLO from the mitochondria to the cytosol in HeLa cells. J Biol Chem. 2002;277:45715-8 pubmed
    ..These results suggest that Smac and cytochrome c may exit the mitochondria by different pathways. ..
  5. Taga M, Miller S, Bassler B. Lsr-mediated transport and processing of AI-2 in Salmonella typhimurium. Mol Microbiol. 2003;50:1411-27 pubmed
    ..Transport and processing of AI-2 could be required for removing the quorum-sensing signal, conveying the signal to an internal detector and/or scavenging boron...
  6. Mooney R, Landick R. Tethering sigma70 to RNA polymerase reveals high in vivo activity of sigma factors and sigma70-dependent pausing at promoter-distal locations. Genes Dev. 2003;17:2839-51 pubmed
    ..coli (i.e., its thermodynamic activity) is close to its bulk concentration. At this level, sigma70 would be a bona fide elongation factor able to direct transcriptional pausing even after its release from RNAP during promoter escape. ..
  7. Zhang X, Beard B, Beebe K, Storer B, Humphries R, Kiem H. Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells. PLoS Med. 2006;3:e173 pubmed
    ..These data should have important implications for the expansion and transplantation of HSCs, in particular for cord blood transplantations where often only suboptimal numbers of HSCs are available. ..
  8. Chun W, Johnson G. Activation of glycogen synthase kinase 3beta promotes the intermolecular association of tau. The use of fluorescence resonance energy transfer microscopy. J Biol Chem. 2007;282:23410-7 pubmed
    ..These data imply that increased association of tau should not be regarded as a direct indicator of the formation of insoluble tau aggregates. ..
  9. Jarry T, Memmi G, Cheung A. The expression of alpha-haemolysin is required for Staphylococcus aureus phagosomal escape after internalization in CFT-1 cells. Cell Microbiol. 2008;10:1801-14 pubmed publisher
    ..These results demonstrate that the expression of agr is required for vesicular escape, and that biologically active alpha-haemolysin is required for S. aureus escape from the endocytic vesicle into the cytosol of CFT-1 cells. ..

More Information

Publications927 found, 100 shown here

  1. Chong P, Drake L, Biswas I. Modulation of covR expression in Streptococcus mutans UA159. J Bacteriol. 2008;190:4478-88 pubmed publisher
    ..A detailed analysis of the regulation of CovR may lead to a better understanding of the pathogenesis of S. mutans, as well as providing further insight into the prevention of dental caries. ..
  2. Dunn M, Niks D, Ngo H, Barends T, Schlichting I. Tryptophan synthase: the workings of a channeling nanomachine. Trends Biochem Sci. 2008;33:254-64 pubmed publisher
  3. Huang Y, Xun R, Chen G, Xun L. Maintenance role of a glutathionyl-hydroquinone lyase (PcpF) in pentachlorophenol degradation by Sphingobium chlorophenolicum ATCC 39723. J Bacteriol. 2008;190:7595-600 pubmed publisher
    ..Thus, PcpF played a maintenance role in PCP degradation and converted the GS-hydroquinone conjugates back to the intermediates of the PCP degradation pathway...
  4. Hernandez J, George S, Rubio L. Molybdenum trafficking for nitrogen fixation. Biochemistry. 2009;48:9711-21 pubmed publisher
    ..Molybdenum biochemistry in A. vinelandii reveals unexpected mechanisms and a new role for iron-sulfur clusters in the sequestration and delivery of molybdenum. ..
  5. Chattoraj P, Banerjee A, Biswas S, Biswas I. ClpP of Streptococcus mutans differentially regulates expression of genomic islands, mutacin production, and antibiotic tolerance. J Bacteriol. 2010;192:1312-23 pubmed publisher
    ..The results presented here indicate that ClpP-mediated proteolysis plays an important global role in the regulation of several important traits in this pathogen. ..
  6. Yi X, Setlow P. Studies of the commitment step in the germination of spores of bacillus species. J Bacteriol. 2010;192:3424-33 pubmed publisher
  7. Amachawadi R, Shelton N, Shi X, Vinasco J, Dritz S, Tokach M, et al. Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. Appl Environ Microbiol. 2011;77:5597-603 pubmed publisher
    ..faecalis strains. The higher prevalence of tcrB-positive enterococci in piglets fed elevated copper compared to that in piglets fed normal copper suggests that supplementation of copper in swine diets selected for resistance. ..
  8. Daily M, Phillips G, Cui Q. Interconversion of functional motions between mesophilic and thermophilic adenylate kinases. PLoS Comput Biol. 2011;7:e1002103 pubmed publisher
    ..This mutational framework can inform the rational design of functionally important flexibility and allostery in other proteins toward engineering novel biochemical pathways. ..
  9. Côté G, Skory C. Cloning, expression, and characterization of an insoluble glucan-producing glucansucrase from Leuconostoc mesenteroides NRRL B-1118. Appl Microbiol Biotechnol. 2012;93:2387-94 pubmed publisher
    ..NMR and methylation analysis of the water-insoluble ?-D-glucan revealed that it had approximately equal amounts of ?(1 ? 3)-linked and ?(1 ? 6)-linked D-glucopyranosyl units and a low degree of branching. ..
  10. Lambrecht J, Flynn J, Downs D. Conserved YjgF protein family deaminates reactive enamine/imine intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme reactions. J Biol Chem. 2012;287:3454-61 pubmed publisher
    ..The conservation of the RidA/YjgF family suggests that reactive enamine/imine metabolites are of concern to all organisms...
  11. Butzin X, Troiano A, Coleman W, Griffiths K, Doona C, Feeherry F, et al. Analysis of the effects of a gerP mutation on the germination of spores of Bacillus subtilis. J Bacteriol. 2012;194:5749-58 pubmed publisher
    ..All these results support the suggestion that GerP proteins facilitate access of nutrient germinants to their cognate GRs in spores' inner membrane. ..
  12. An B, DesRochers T, Qin G, Xia X, Thiagarajan G, Brodsky B, et al. The influence of specific binding of collagen-silk chimeras to silk biomaterials on hMSC behavior. Biomaterials. 2013;34:402-12 pubmed publisher
  13. Zeng L, Burne R. Comprehensive mutational analysis of sucrose-metabolizing pathways in Streptococcus mutans reveals novel roles for the sucrose phosphotransferase system permease. J Bacteriol. 2013;195:833-43 pubmed publisher
    ..Sucrose-dependent catabolite repression was also evident in strains containing an intact sucrose PTS. Collectively, these results reveal a novel regulatory circuitry for the control of sucrose catabolism, with a central role for ScrA...
  14. Young J, Locke J, Elowitz M. Rate of environmental change determines stress response specificity. Proc Natl Acad Sci U S A. 2013;110:4140-5 pubmed publisher
    ..Such dynamic control of specificity could be a critical function of other general stress response pathways. ..
  15. Palmer G, Jorth P, Whiteley M. The role of two Pseudomonas aeruginosa anthranilate synthases in tryptophan and quorum signal production. Microbiology. 2013;159:959-69 pubmed publisher
    ..aeruginosa trpEG mutant. Based on these data, we propose a model for anthranilate sequestration by differential transcriptional regulation of the two P. aeruginosa anthranilate synthase enzymes. ..
  16. Westerhold L, Bridges L, Shaikh S, Zeczycki T. Kinetic and Thermodynamic Analysis of Acetyl-CoA Activation of Staphylococcus aureus Pyruvate Carboxylase. Biochemistry. 2017;56:3492-3506 pubmed publisher
    ..Taken together, our kinetic and thermodynamic results provide a possible allosteric mechanism by which acetyl-CoA coordinates catalysis within the PC tetramer. ..
  17. Liang F, Nowling J, Philipp M. Cryptic and exposed invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi sl. J Bacteriol. 2000;182:3597-601 pubmed
    ..However, negative surface immunofluorescence and in vitro antibody-mediated killing results indicated that none of the IRs were accessible to antibody at the spirochetal surface in vitro. ..
  18. Vesey P, Kuramitsu H. Genetic analysis of Treponema denticola ATCC 35405 biofilm formation. Microbiology. 2004;150:2401-7 pubmed
    ..In contrast, T. denticola lacking the PrtP protein for prolyl-phenylalanine-specific protease, showed an increased ability to form mixed biofilms and a prolonged viability in the biofilm...
  19. Mason K, Munson R, Bakaletz L. A mutation in the sap operon attenuates survival of nontypeable Haemophilus influenzae in a chinchilla model of otitis media. Infect Immun. 2005;73:599-608 pubmed
    ..Our results indicate that the products of the sap operon are important for resisting the activity of APs and may regulate, in part, the balance between normal carriage and disease caused by NTHI...
  20. Suprenant K, Bloom N, Fang J, Lushington G. The major vault protein is related to the toxic anion resistance protein (TelA) family. J Exp Biol. 2007;210:946-55 pubmed publisher
    ..In addition, vaultosomes form independently from other stress-induced ribonucleoprotein complexes, stress granules and aggresomes. Vaultosome formation is therefore a unique cellular response to an environmental toxin...
  21. Al Khodor S, Price C, Kalia A, Abu Kwaik Y. Functional diversity of ankyrin repeats in microbial proteins. Trends Microbiol. 2010;18:132-9 pubmed publisher
    ..Studying the molecular and biochemical functions of this family of proteins will enhance our understanding of important host-microbe interactions. ..
  22. Lee P, Stopford C, Svenson A, Rietsch A. Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV. Mol Microbiol. 2010;75:924-41 pubmed publisher
    ..Taken together, these data allow us to propose a working model for control of effector secretion by PcrG and PcrV...
  23. Shen B, Lutkenhaus J. Differences in MinC/MinD sensitivity between polar and internal Z rings in Escherichia coli. J Bacteriol. 2011;193:367-76 pubmed publisher
    ..Taken together, these data indicate that polar Z rings are more susceptible to MinC/MinD than internal Z rings, even when MinE is absent. ..
  24. Wilson R, Kumar P, Parashar V, Vilchèze C, Veyron Churlet R, Freundlich J, et al. Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis. Nat Chem Biol. 2013;9:499-506 pubmed publisher
    ..tuberculosis Pks13 is required for mycolic acid biosynthesis, validates it as a druggable target and demonstrates the therapeutic potential of simultaneously inhibiting multiple targets in the same biosynthetic pathway. ..
  25. Dombroski A, Walter W, Record M, Siegele D, Gross C. Polypeptides containing highly conserved regions of transcription initiation factor sigma 70 exhibit specificity of binding to promoter DNA. Cell. 1992;70:501-12 pubmed
    ..Thus, we propose that sigma 70 is a sequence-specific DNA-binding protein that normally functions through an allosteric interaction with the core subunits of RNA polymerase. ..
  26. Plano G, Barve S, Straley S. LcrD, a membrane-bound regulator of the Yersinia pestis low-calcium response. J Bacteriol. 1991;173:7293-303 pubmed
    ..The alkaline phosphatase activities of the resultant hybrid proteins were consistent with a model predicting eight amino-terminal transmembrane segments that anchor a large cytoplasmic carboxyl-terminal domain to the inner membrane...
  27. Palenchar P, Buck C, Cheng H, Larson T, Mueller E. Evidence that ThiI, an enzyme shared between thiamin and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate. J Biol Chem. 2000;275:8283-6 pubmed
    ..To accommodate this hypothesis, we propose a general mechanism for sulfur transfer in which the terminal sulfur of the persulfide first acts as a nucleophile and is then transferred as an equivalent of S(2-) rather than S(0). ..
  28. Kielian T, Cheung A, Hickey W. Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses. Infect Immun. 2001;69:6902-11 pubmed
    ..aureus intracellularly, providing a means by which the organism may establish chronic infections in the brain. Together, these data identify alpha-toxin as a key virulence determinant for the survival of S. aureus in the brain. ..
  29. Mehta S, Yang X, Chan C, Dobson M, Jayaram M, Velmurugan S. The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation?. J Cell Biol. 2002;158:625-37 pubmed
    ..Cohesin-mediated pairing and unpairing likely provides a counting mechanism for evenly partitioning plasmids either in association with or independently of the chromosomes. ..
  30. Ingavale S, van Wamel W, Cheung A. Characterization of RAT, an autolysis regulator in Staphylococcus aureus. Mol Microbiol. 2003;48:1451-66 pubmed
    ..As anticipated, rat appears to be a negative regulator of autolysin genes including lytM and lytN. These data suggest that the rat gene product is an important regulator of autolytic activity in S. aureus...
  31. Matthews M, Periyannan G, Hajdin C, Sidgel T, Bennett B, Crowder M. Probing the reaction mechanism of the D-ala-D-ala dipeptidase, VanX, by using stopped-flow kinetic and rapid-freeze quench EPR studies on the Co(II)-substituted enzyme. J Am Chem Soc. 2006;128:13050-1 pubmed
    ..The EPR studies also identified a distinct enzyme product complex. The results were used to offer a detailed reaction mechanism for VanX that can be used to guide future inhibitor design efforts. ..
  32. Edwards J. Neisseria gonorrhoeae survival during primary human cervical epithelial cell infection requires nitric oxide and is augmented by progesterone. Infect Immun. 2010;78:1202-13 pubmed publisher
    ..In addition, these data demonstrate that host-derived nitric oxide likely is not protective against gonococci, in vivo; rather, nitric oxide may be required to sustain cervical bacterial disease. ..
  33. Perez F, Pultz M, Endimiani A, Bonomo R, Donskey C. Effect of antibiotic treatment on establishment and elimination of intestinal colonization by KPC-producing Klebsiella pneumoniae in mice. Antimicrob Agents Chemother. 2011;55:2585-9 pubmed publisher
    ..The administration of nonabsorbed oral antibiotics may be an effective strategy to suppress colonization with KPC-Kp. ..
  34. Callahan B, Topilina N, Stanger M, Van Roey P, Belfort M. Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications. Nat Struct Mol Biol. 2011;18:630-3 pubmed publisher
    ..A natural analog of the designed system was identified in Pyrococcus abyssi, suggesting an unprecedented form of adaptive, post-translational regulation. ..
  35. El Gazzar M, Wetzel A, Raviv Z. The genotyping potential of the Mycoplasma synoviae vlhA gene. Avian Dis. 2012;56:711-9 pubmed
    ..In addition, this study allows interesting insight into the gene conversion mechanism of MS and offers the opportunity for further investigation this mechanism in mycoplasmas...
  36. Bannantine J, Lingle C, Adam P, Ramyar K, McWhorter W, Stabel J, et al. NlpC/P60 domain-containing proteins of Mycobacterium avium subspecies paratuberculosis that differentially bind and hydrolyze peptidoglycan. Protein Sci. 2016;25:840-51 pubmed publisher
    ..Collectively, these findings suggest a broader functional repertoire for NlpC/P60 domain-containing proteins than simply hydrolases. ..
  37. Rosey E, Stewart G. Nucleotide and deduced amino acid sequences of the lacR, lacABCD, and lacFE genes encoding the repressor, tagatose 6-phosphate gene cluster, and sugar-specific phosphotransferase system components of the lactose operon of Streptococcus mutans. J Bacteriol. 1992;174:6159-70 pubmed
    ..mutans lac promoter appears to contain repeat elements analogous to those of S. aureus, suggesting that repression and catabolite repression of the lactose operons may be similar in these organisms...
  38. Tabassum R, Sandman K, Reeve J. HMt, a histone-related protein from Methanobacterium thermoautotrophicum delta H. J Bacteriol. 1992;174:7890-5 pubmed
    ..Histone-related proteins with these properties are therefore not limited to reverse gyrase-containing hyperthermophilic species. ..
  39. Wu J, Newton A. Isolation, identification, and transcriptional specificity of the heat shock sigma factor sigma32 from Caulobacter crescentus. J Bacteriol. 1996;178:2094-101 pubmed
    ..crescentus sigma32 appear to be very similar to those of its E. coli counterpart, the C. crescentus rpoH gene contains a novel promoter structure and may be positively autoregulated in response to environmental stress. ..
  40. Nakano M. Induction of ResDE-dependent gene expression in Bacillus subtilis in response to nitric oxide and nitrosative stress. J Bacteriol. 2002;184:1783-7 pubmed
    ..Among members of the ResDE regulon, only the flavohemoglobin gene was induced by nitrosative stress via both a ResDE-dependent mechanism and an unidentified ResDE-independent mechanism. ..
  41. Dong Y, Chen Y, Snyder J, Burne R. Isolation and molecular analysis of the gene cluster for the arginine deiminase system from Streptococcus gordonii DL1. Appl Environ Microbiol. 2002;68:5549-53 pubmed
    ..Thus, ArcR is a transcriptional activator that is required for induction and optimal expression of the S. gordonii ADS gene cluster...
  42. González E, Allen C. Characterization of a Ralstonia solanacearum operon required for polygalacturonate degradation and uptake of galacturonic acid. Mol Plant Microbe Interact. 2003;16:536-44 pubmed
    ..This exuT mutant had wild-type virulence on tomato, demonstrating that metabolism of galacturonic acid does not contribute significantly to bacterial success inside the plant...
  43. Newberry K, Brennan R. The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. J Biol Chem. 2004;279:20356-62 pubmed
    ..Analysis of the structures of BmrR, CueR, and ZntR indicates that this hinge may be common to all MerR family members. ..
  44. Tans Kersten J, Brown D, Allen C. Swimming motility, a virulence trait of Ralstonia solanacearum, is regulated by FlhDC and the plant host environment. Mol Plant Microbe Interact. 2004;17:686-95 pubmed
    ..Thus, expression of flhDC and flagellin itself are uncoupled from bacterial motility in the host environment, indicating that additional signals and regulatory circuits repress motility during plant pathogenesis...
  45. Jilaveanu L, Zito C, Oliver D. Dimeric SecA is essential for protein translocation. Proc Natl Acad Sci U S A. 2005;102:7511-6 pubmed
    ..Our findings have important implications regarding SecA motor function and translocon assembly and activation. ..
  46. Zhang P, Martin M, Michalek S, Katz J. Role of mitogen-activated protein kinases and NF-kappaB in the regulation of proinflammatory and anti-inflammatory cytokines by Porphyromonas gingivalis hemagglutinin B. Infect Immun. 2005;73:3990-8 pubmed
    ..Taken together, our results demonstrate a role for the p38 and ERK pathways and the transcription factor NF-kappaB in modulating key immunoregulatory cytokines involved in the development of immune responses to P. gingivalis HagB. ..
  47. Robert Seilaniantz A, Shan L, Zhou J, Tang X. The Pseudomonas syringae pv. tomato DC3000 type III effector HopF2 has a putative myristoylation site required for its avirulence and virulence functions. Mol Plant Microbe Interact. 2006;19:130-8 pubmed
    ..HopF2 contains a putative myristoylation site. Mutational analysis indicated that this site is required for plasma membrane localization and virulence and avirulence activities of HopF2. ..
  48. Dajkovic A, Mukherjee A, Lutkenhaus J. Investigation of regulation of FtsZ assembly by SulA and development of a model for FtsZ polymerization. J Bacteriol. 2008;190:2513-26 pubmed publisher
    ..In vivo stoichiometry of the disruption of Z rings by SulA suggests that FtsZ may undergo two cooperative transitions in forming the Z ring. ..
  49. Hayden J, Ades S. The extracytoplasmic stress factor, sigmaE, is required to maintain cell envelope integrity in Escherichia coli. PLoS ONE. 2008;3:e1573 pubmed publisher
    ..Our results are consistent with a model in which overexpression of ptsN reduces stress in the cell envelope, thereby promoting survival in the absence of sigma(E). ..
  50. Rocco C, Dennison K, Klenchin V, Rayment I, Escalante Semerena J. Construction and use of new cloning vectors for the rapid isolation of recombinant proteins from Escherichia coli. Plasmid. 2008;59:231-7 pubmed publisher
  51. Rentmeister A, Arnold F, Fasan R. Chemo-enzymatic fluorination of unactivated organic compounds. Nat Chem Biol. 2009;5:26-8 pubmed publisher
    ..This procedure was applied for the rapid identification of fluorinated drug derivatives with enhanced membrane permeability. ..
  52. Konkel M, Larson C, Flanagan R. Campylobacter jejuni FlpA binds fibronectin and is required for maximal host cell adherence. J Bacteriol. 2010;192:68-76 pubmed publisher
    ..Based on these data, we conclude that FlpA mediates C. jejuni attachment to host epithelial cells via Fn binding. ..
  53. Greenwell R, Nam T, Donohue T. Features of Rhodobacter sphaeroides ChrR required for stimuli to promote the dissociation of ?(E)/ChrR complexes. J Mol Biol. 2011;407:477-91 pubmed publisher
    ..Finally, we found that the same aspects of R. sphaeroides ChrR needed for a response to (1)O(2) are required for the dissociation of ?(E)/ChrR complexes in the presence of the organic hydroperoxide t-butyl hydroperoxide...
  54. Jahn C, Selimi D, Barak J, Charkowski A. The Dickeya dadantii biofilm matrix consists of cellulose nanofibres, and is an emergent property dependent upon the type III secretion system and the cellulose synthesis operon. Microbiology. 2011;157:2733-44 pubmed publisher
    ..Mutation of the cellulose synthase bcsA or of bcsC resulted in decreased accumulation of the T3SS-secreted protein HrpN. ..
  55. Lee Y, Mick J, Furdui C, Beamer L. A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family. PLoS ONE. 2012;7:e38114 pubmed publisher
    ..This work adds to our understanding of the functional roles of coevolving residue networks, and has implications for the definition of catalytically important residues. ..
  56. Hemarajata P, Yang S, Soge O, Humphries R, Klausner J. Performance and Verification of a Real-Time PCR Assay Targeting the gyrA Gene for Prediction of Ciprofloxacin Resistance in Neisseria gonorrhoeae. J Clin Microbiol. 2016;54:805-8 pubmed publisher
    ..Among 76 clinical urine and swab specimens positive for N. gonorrhoeae by the Cobas assay, 71% could be genotyped. The test took 1.5 h to perform, allowing the physician to receive results in time to make informed clinical decisions. ..
  57. Ford N, Hecht K, Hu D, Orr G, Xiong Y, Squier T, et al. Antigen Binding and Site-Directed Labeling of Biosilica-Immobilized Fusion Proteins Expressed in Diatoms. ACS Synth Biol. 2016;5:193-9 pubmed publisher
    ..In conclusion, our results demonstrate an ability to engineer diatoms to create antibody-functionalized mesoporous silica able to selectively bind chemical and biological agents for the development of sensing platforms. ..
  58. Chilton S, Falbel T, Hromada S, Burton B. A Conserved Metal Binding Motif in the Bacillus subtilis Competence Protein ComFA Enhances Transformation. J Bacteriol. 2017;199: pubmed publisher
    ..We demonstrate that several amino acid motifs conserved among ComFA proteins are important for efficient transformation. This report is the first to demonstrate the functional requirement of an amino-terminal cysteine motif in ComFA. ..
  59. Ebel W, Trempy J. Escherichia coli RcsA, a positive activator of colanic acid capsular polysaccharide synthesis, functions To activate its own expression. J Bacteriol. 1999;181:577-84 pubmed
    ..coli cps promoter and the Erwinia amylovora ams promoter and previously shown to be the RcsA-RcsB binding site, was identified in the rcsA promoter region and shown to be required for high-level expression of rcsA. ..
  60. Carlos J, Paetzel M, Brubaker G, Karla A, Ashwell C, Lively M, et al. The role of the membrane-spanning domain of type I signal peptidases in substrate cleavage site selection. J Biol Chem. 2000;275:38813-22 pubmed
    ..In contrast, certain mutants in the c-region of the signal peptide result in alternate site cleavage by both Lep and SipS enzymes...
  61. Swem L, Elsen S, Bird T, Swem D, Koch H, Myllykallio H, et al. The RegB/RegA two-component regulatory system controls synthesis of photosynthesis and respiratory electron transfer components in Rhodobacter capsulatus. J Mol Biol. 2001;309:121-38 pubmed
    ..These data provide evidence that the RegB/RegA two-component system has a major role in controlling the synthesis of numerous processes that affect reducing equivalents in Rhodobacter capsulatus...
  62. Rajagopalan P, Lutz S, Benkovic S. Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates. Biochemistry. 2002;41:12618-28 pubmed
    ..Natl. Acad. Sci. U.S.A. 99, 2794-2799], the data suggest that a coupled dynamic motion of these distal residues enhances crossing of the chemical reaction barrier and imply an expanded nonstatic role for the protein fold in catalysis. ..
  63. Geller B, Deere J, Stein D, Kroeker A, Moulton H, Iversen P. Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers. Antimicrob Agents Chemother. 2003;47:3233-9 pubmed
    ..We conclude that the outer membrane of E. coli inhibits entry of PMOs and that (KFF)(3)KC-PMO conjugates are transported across both membranes and specifically inhibit expression of their genetic targets. ..
  64. Gong X, Yu L, Xia D, Yu C. Evidence for electron equilibrium between the two hemes bL in the dimeric cytochrome bc1 complex. J Biol Chem. 2005;280:9251-7 pubmed
    ..This supports the idea that the interruption of electron transfer between the two bL hemes enhances electron leakage to oxygen and thus decreases the ubiquinol-cytochrome c reductase activity. ..
  65. Tsenova L, Harbacheuski R, Moreira A, Ellison E, Dalemans W, Alderson M, et al. Evaluation of the Mtb72F polyprotein vaccine in a rabbit model of tuberculous meningitis. Infect Immun. 2006;74:2392-401 pubmed
    ..Interestingly, Mtb72F+AS01B induced better protection against leukocytosis and weight loss, suggesting that the polyprotein in this adjuvant may boost immunity without exacerbating inflammation in previously BCG-vaccinated individuals. ..
  66. He X, Thornton J, Carmicle Davis S, McDaniel L. Tex, a putative transcriptional accessory factor, is involved in pathogen fitness in Streptococcus pneumoniae. Microb Pathog. 2006;41:199-206 pubmed
    ..The interaction between recombinant Tex and nucleic acids was confirmed by southwestern and northwestern analysis, supporting its role as a transcriptional accessory factor. ..
  67. Running W, Ravipaty S, Karty J, Reilly J. A top-down/bottom-up study of the ribosomal proteins of Caulobacter crescentus. J Proteome Res. 2007;6:337-47 pubmed
  68. Purdy G, Fisher C, Payne S. IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA. J Bacteriol. 2007;189:5566-73 pubmed
    ..Therefore, the three periplasmic folding factors DegP, Skp, and SurA were all required for IcsA localization and plaque formation by S. flexneri. ..
  69. Colangeli R, Helb D, Vilcheze C, Hazbón M, Lee C, Safi H, et al. Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis. PLoS Pathog. 2007;3:e87 pubmed
    ..An improved understanding of the role of lsr2 may provide important insights into the mechanisms of action of antibiotics and the way that mycobacteria adapt to stresses such as antibiotic treatment. ..
  70. Ayala Castro C, Saini A, Outten F. Fe-S cluster assembly pathways in bacteria. Microbiol Mol Biol Rev. 2008;72:110-25, table of contents pubmed publisher
    ..Here we attempt to summarize recent advances and to highlight new avenues of research in the field of Fe-S cluster assembly. ..
  71. Rice L, Lakticova V, Carias L, Rudin S, Hutton R, Marshall S. Transferable capacity for gastrointestinal colonization in Enterococcus faecium in a mouse model. J Infect Dis. 2009;199:342-9 pubmed publisher
    ..These results indicate that E. faecium clinical isolates express transmissible factors other than antimicrobial resistance that promote colonization of the mouse gastrointestinal tract. ..
  72. Smith T, Hoover T. Deciphering bacterial flagellar gene regulatory networks in the genomic era. Adv Appl Microbiol. 2009;67:257-95 pubmed publisher
    ..Finally, we review the prominent systems that utilize sigma(28) and its antagonist, the anti-sigma(28) factor FlgM, along with some systems that utilize alternative mechanisms for regulating flagellar gene expression. ..
  73. Zhang Y, Pohlmann E, Serate J, Conrad M, Roberts G. Mutagenesis and functional characterization of the four domains of GlnD, a bifunctional nitrogen sensor protein. J Bacteriol. 2010;192:2711-21 pubmed publisher
    ..The deletion of C-terminal ACT domains also dramatically decreased UTase activity under all conditions tested, but some of these effects are due to the competition of UTase activity with unregulated UR activity in these variants...
  74. Drage M, Tsai H, Pecora N, Cheng T, Arida A, Shukla S, et al. Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nat Struct Mol Biol. 2010;17:1088-95 pubmed publisher
    ..In conclusion, we demonstrate a glycolipid binding function of LprG that enhances recognition of triacylated MTB glycolipids by TLR2 and may affect glycolipid assembly or transport for bacterial cell wall biogenesis. ..
  75. Yang Y, Ramelot T, McCarrick R, Ni S, Feldmann E, Cort J, et al. Combining NMR and EPR methods for homodimer protein structure determination. J Am Chem Soc. 2010;132:11910-3 pubmed publisher
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