Genomes and Genes
Experts and Doctors on bacillus subtilis in Germany
Topic: bacillus subtilis
Publications198 found, 100 shown here
- Gunka K, Newman J, Commichau F, Herzberg C, Rodrigues C, Hewitt L, et al. Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties. J Mol Biol. 2010;400:815-27 pubmed publisher
- Meyer F, Jules M, Mehne F, Le Coq D, Landmann J, G rke B, et al. Malate-mediated carbon catabolite repression in Bacillus subtilis involves the HPrK/CcpA pathway. J Bacteriol. 2011;193:6939-49 pubmed publisher..The repression strength of target promoters was similar to that observed in steady-state growth conditions, although it took somewhat longer to reach the second steady-state of expression when cells were shifted to malate...
- Sedlmeier R, Werner T, Kieser H, Hopwood D, Schmieger H. tRNA genes of Streptomyces lividans: new sequences and comparison of structure and organization with those of other bacteria. J Bacteriol. 1994;176:5550-3 pubmed..The structure and organization of tRNA genes of S. lividans and S. coelicolor are compared with those of Escherichia coli and Bacillus subtilis...
- Kravanja M, Engelmann R, Dossonnet V, Blüggel M, Meyer H, Frank R, et al. The hprK gene of Enterococcus faecalis encodes a novel bifunctional enzyme: the HPr kinase/phosphatase. Mol Microbiol. 1999;31:59-66 pubmed..subtilis enzyme to the kinase activity. A change in activity of the B. subtilis HPr kinase was only observed when fructose-1,6-bisphosphate was also present. ..
- Hecht S, Kis K, Eisenreich W, Amslinger S, Wungsintaweekul J, Herz S, et al. Enzyme-assisted preparation of isotope-labeled 1-deoxy-d-xylulose 5-phosphate. J Org Chem. 2001;66:3948-52 pubmed..The simple one-pot methods described afford almost every conceivable isotopomer of 1-deoxy-D-xylulose 5-phosphate carrying (13)C or (14)C from commercially available precursors with an overall yield around 50%. ..
- Hofemeister J, Conrad B, Adler B, Hofemeister B, Feesche J, Kucheryava N, et al. Genetic analysis of the biosynthesis of non-ribosomal peptide- and polyketide-like antibiotics, iron uptake and biofilm formation by Bacillus subtilis A1/3. Mol Genet Genomics. 2004;272:363-78 pubmed..The formation of biofilms (pellicles) was shown to require the production of surfactins, but no other lipopeptides, indicating that surfactins serve specific developmental functions. ..
- Augustyniak W, Brzezinska A, Pijning T, Wienk H, Boelens R, Dijkstra B, et al. Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention. Protein Sci. 2012;21:487-97 pubmed publisher..Reduced precipitation of the unfolding intermediates rather than increased conformational stability of the evolved mutants seems to be responsible for the activity retention. ..
- Beckert B, Abdelshahid M, Schäfer H, Steinchen W, Arenz S, Berninghausen O, et al. Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. EMBO J. 2017;36:2061-2072 pubmed publisher..coli. ..
- Schumacher D, Bergeler S, Harms A, Vonck J, Huneke Vogt S, Frey E, et al. The PomXYZ Proteins Self-Organize on the Bacterial Nucleoid to Stimulate Cell Division. Dev Cell. 2017;41:299-314.e13 pubmed publisher..At midcell, fluxes equalize resulting in constrained motion. Flux-based mechanisms may represent a general paradigm for positioning of macromolecular structures in bacteria. ..
- Schönert S, Buder T, Dahl M. Properties of maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) in Bacillus subtilis: evidence for its contribution to maltodextrin utilization. Res Microbiol. 1999;150:167-77 pubmed..Furthermore, MalL expression varies temporally, showing a second induction in the stationary growth phase. ..
- Zellmeier S, Zuber U, Schumann W, Wiegert T. The absence of FtsH metalloprotease activity causes overexpression of the sigmaW-controlled pbpE gene, resulting in filamentous growth of Bacillus subtilis. J Bacteriol. 2003;185:973-82 pubmed..DNA macroarray analysis revealed that most genes of the sigma(W) regulon are transcribed at elevated levels in an ftsH mutant. The influence of FtsH on sigma(W)-controlled genes is discussed. ..
- Guldan H, Sterner R, Babinger P. Identification and characterization of a bacterial glycerol-1-phosphate dehydrogenase: Ni(2+)-dependent AraM from Bacillus subtilis. Biochemistry. 2008;47:7376-84 pubmed publisher..On the basis of these findings and the analysis of an araM knockout mutant, we propose that AraM generates G1P for the synthesis of phosphoglycerolipids in Gram-positive bacterial species...
- Singh K, Schmalisch M, Stülke J, Görke B. Carbon catabolite repression in Bacillus subtilis: quantitative analysis of repression exerted by different carbon sources. J Bacteriol. 2008;190:7275-84 pubmed publisher..Our data suggest that the hierarchy in CCR exerted by the different substrates is exclusively determined by the activity of HPrK/P. ..
- Röhrl J, Yang D, Oppenheim J, Hehlgans T. Specific binding and chemotactic activity of mBD4 and its functional orthologue hBD2 to CCR6-expressing cells. J Biol Chem. 2010;285:7028-34 pubmed publisher..Thus, the beta-defensin fusion proteins used in this study retained their biological activity and are a feasible tool to identify and analyze specific beta-defensin receptor interactions. ..
- Richter S, Messer W. Genetic structure of the dnaA region of the cyanobacterium Synechocystis sp. strain PCC6803. J Bacteriol. 1995;177:4245-51 pubmed..Downstream of the dnaA gene we detected the start of the psbDC operon, which codes for the photosystem II reaction center proteins D2 and CP43 that are involved in the positioning of chlorophyll a. ..
- Klein C, Kaletta C, Entian K. Biosynthesis of the lantibiotic subtilin is regulated by a histidine kinase/response regulator system. Appl Environ Microbiol. 1993;59:296-303 pubmed..Gene deletions within spaR and spaK yielded subtilin-negative mutants, which confirms that subtilin biosynthesis is under the control of a two-component regulatory system.(ABSTRACT TRUNCATED AT 250 WORDS) ..
- Alpert C, Siebers U. The lac operon of Lactobacillus casei contains lacT, a gene coding for a protein of the Bg1G family of transcriptional antiterminators. J Bacteriol. 1997;179:1555-62 pubmed..casei does not contain the genes of the accessory tagatose-6-phosphate pathway as occurs in the lac operons of Lactococcus lactis, Streptococcus mutans, or Staphylococcus aureus. ..
- Albrecht A, Netz D, Miethke M, Pierik A, Burghaus O, Peuckert F, et al. SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis. J Bacteriol. 2010;192:1643-51 pubmed publisher..SufS-dependent formation of holo-SufU suggests that SufU functions as an Fe/S cluster scaffold protein tightly cooperating with the SufS cysteine desulfurase. ..
- Miethke M, Monteferrante C, Marahiel M, van Dijl J. The Bacillus subtilis EfeUOB transporter is essential for high-affinity acquisition of ferrous and ferric iron. Biochim Biophys Acta. 2013;1833:2267-78 pubmed publisher..In conclusion, the EfeUOB system contributes to the high-affinity uptake of iron that is available in two different oxidation states. ..
- Mascarenhas J, Volkov A, Rinn C, Schiener J, Guckenberger R, Graumann P. Dynamic assembly, localization and proteolysis of the Bacillus subtilis SMC complex. BMC Cell Biol. 2005;6:28 pubmed..Because the cellular concentration of SMC protein is also regulated at the posttranscriptional level, the activity of SMC is apparently regulated at multiple levels. ..
- Ruckert C, Koch D, Rey D, Albersmeier A, Mormann S, Pühler A, et al. Functional genomics and expression analysis of the Corynebacterium glutamicum fpr2-cysIXHDNYZ gene cluster involved in assimilatory sulphate reduction. BMC Genomics. 2005;6:121 pubmed..coli and B. subtilis is used by members of this order, providing the basis for further biochemical studies. ..
- Seibel J, Moraru R, Götze S, Buchholz K, Na amnieh S, Pawlowski A, et al. Synthesis of sucrose analogues and the mechanism of action of Bacillus subtilis fructosyltransferase (levansucrase). Carbohydr Res. 2006;341:2335-49 pubmed..In those conformations, the L-glycopyranosides are stabilized by the same hydrogen network. Structures of the acceptor products were determined by NMR and mass spectrometry analysis. ..
- Gubaev A, Klostermeier D. DNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passage. Proc Natl Acad Sci U S A. 2011;108:14085-90 pubmed publisher..The N-gate reopens after ATP hydrolysis, allowing for further catalytic cycles. DNA binding, cleavage, and wrapping and N-gate narrowing are intimately linked events that coordinate conformational changes at the DNA and the N-gate. ..
- Stein T, Heinzmann S, Solovieva I, Entian K. Function of Lactococcus lactis nisin immunity genes nisI and nisFEG after coordinated expression in the surrogate host Bacillus subtilis. J Biol Chem. 2003;278:89-94 pubmed..subtilis membrane vesicles and recombinant hexahistidine-tagged NisI from Escherichia coli interacted specifically with nisin and not with subtilin. This suggests a function of NisI as a nisin-intercepting protein. ..
- Volkov A, Mascarenhas J, Andrei Selmer C, Ulrich H, Graumann P. A prokaryotic condensin/cohesin-like complex can actively compact chromosomes from a single position on the nucleoid and binds to DNA as a ring-like structure. Mol Cell Biol. 2003;23:5638-50 pubmed
- Gimpel M, Heidrich N, Mäder U, Krügel H, Brantl S. A dual-function sRNA from B. subtilis: SR1 acts as a peptide encoding mRNA on the gapA operon. Mol Microbiol. 2010;76:990-1009 pubmed publisher..We show that SR1P binds GapA, thereby stabilizing the gapA operon mRNA by a hitherto unknown mechanism. SR1 is the first dual-function sRNA found in B. subtilis. ..
- Hoffmann T, von Blohn C, Stanek A, Moses S, Barzantny H, Bremer E. Synthesis, release, and recapture of compatible solute proline by osmotically stressed Bacillus subtilis cells. Appl Environ Microbiol. 2012;78:5753-62 pubmed publisher..subtilis cells. The wider implications of our findings for the retention of compatible solutes by osmotically challenged microorganisms and the roles of uptake systems for compatible solutes are considered...
- Henrich E, Ma Y, Engels I, MÃ¼nch D, Otten C, Schneider T, et al. Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway. J Biol Chem. 2016;291:2535-46 pubmed publisher..As a proof of principle for future screening platforms, we demonstrate the inhibition of the in vitro lipid II biosynthesis with the specific inhibitors fosfomycin, feglymycin, and tunicamycin. ..
- Volker U, Engelmann S, Maul B, Riethdorf S, Volker A, Schmid R, et al. Analysis of the induction of general stress proteins of Bacillus subtilis. Microbiology. 1994;140 ( Pt 4):741-52 pubmed..However, all the five Hsps were induced in this mutant in response to heat shock. These data indicate that SigB plays a crucial role in the induction of general stress genes, but is dispensable for the induction of Hsps. ..
- Eppelmann K, Doekel S, Marahiel M. Engineered biosynthesis of the peptide antibiotic bacitracin in the surrogate host Bacillus subtilis. J Biol Chem. 2001;276:34824-31 pubmed..This engineered and genetically amenable B. subtilis strain will facilitate the rational design of new bacitracin derivatives. ..
- Attin T, Zirkel C, Pelz K. Antibacterial properties of electron beam-sterilized Gutta-Percha cones. J Endod. 2001;27:172-4 pubmed..Both the tested sterilized and unsterilized GPCs impair the growth of endodontic pathogens, with no influence of the time elapsed since sterilization. ..
- Mootz H, Schörgendorfer K, Marahiel M. Functional characterization of 4'-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5. FEMS Microbiol Lett. 2002;213:51-7 pubmed..The complementation system described also provides the basis for a simple method of functional characterization of PPTase candidate genes and their cloning from chromosomal DNA or cDNA libraries of diverse origin. ..
- Miethke M, Klotz O, Linne U, May J, Beckering C, Marahiel M. Ferri-bacillibactin uptake and hydrolysis in Bacillus subtilis. Mol Microbiol. 2006;61:1413-27 pubmed..Thus, ferri-BB was the preferred substrate of the YuiI esterase whose gene locus was designated besA...
- Grimm C, Ficner R, Sgraja T, Haebel P, Klebe G, Reuter K. Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase. Biochem Biophys Res Commun. 2006;351:695-701 pubmed publisher..Comparison of the B. subtilis QueA structure with the structure of QueA from Thermotoga maritima suggests a high domain flexibility of this enzyme...
- Linne U, Schafer A, Stubbs M, Marahiel M. Aminoacyl-coenzyme A synthesis catalyzed by adenylation domains. FEBS Lett. 2007;581:905-10 pubmed..Product quantification for kinetic determination was carried out by ESI-SIM-MS. Our results allow speculation as to evolutionary relationships within the large class of adenylate forming enzymes. ..
- Wiegeshoff F, Marahiel M. Characterization of a mutation in the acetolactate synthase of Bacillus subtilis that causes a cold-sensitive phenotype. FEMS Microbiol Lett. 2007;272:30-4 pubmed..This results in an amino acid substitution from lysine at position 176 to glycine. As a consequence, the acetolactate synthase efficiency in strain JH642 was found to be reduced by 51-fold. ..
- Macek B, Gnad F, Soufi B, Kumar C, Olsen J, Mijakovic I, et al. Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Mol Cell Proteomics. 2008;7:299-307 pubmed..Our results establish Ser/Thr/Tyr phosphorylation as a common posttranslational modification in Eubacteria, present since the onset of cellular life. ..
- Wolf D, Kalamorz F, Wecke T, Juszczak A, M der U, Homuth G, et al. In-depth profiling of the LiaR response of Bacillus subtilis. J Bacteriol. 2010;192:4680-93 pubmed publisher..Our data suggest that the LiaFSR system of B. subtilis and, presumably, other Firmicutes bacilli coordinates a phage shock protein-like response...
- Gimpel M, Preis H, Barth E, Gramzow L, Brantl S. SR1--a small RNA with two remarkably conserved functions. Nucleic Acids Res. 2012;40:11659-72 pubmed publisher..In vitro binding assays with six SR1/ahrC pairs suggest that-despite divergent primary sequences-the base-pairing function is also preserved. In summary, SR1 is an sRNA with two functions that have been conserved over ?1 billion years. ..
- Mehne F, Gunka K, Eilers H, Herzberg C, Kaever V, Stülke J. Cyclic di-AMP homeostasis in bacillus subtilis: both lack and high level accumulation of the nucleotide are detrimental for cell growth. J Biol Chem. 2013;288:2004-17 pubmed publisher..Taken together, our results support the idea of an important role for c-di-AMP in B. subtilis and suggest that the levels of the nucleotide have to be tightly controlled. ..
- Gundlach J, Herzberg C, Kaever V, Gunka K, Hoffmann T, Weis M, et al. Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis. Sci Signal. 2017;10: pubmed publisher..Thus, our results indicated that the control of potassium homeostasis is an essential function of c-di-AMP. ..
- Schnuchel A, Wiltscheck R, Czisch M, Herrler M, Willimsky G, Graumann P, et al. Structure in solution of the major cold-shock protein from Bacillus subtilis. Nature. 1993;364:169-71 pubmed..CspB binds to single-stranded DNA in gel retardation experiments. ..
- Maskey R, Shaaban M, Grün Wollny I, Laatsch H. Quinazolin-4-one derivatives from Streptomyces isolates. J Nat Prod. 2004;67:1131-4 pubmed
- Jauch R, Humm A, Huber R, Wahl M. Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements. J Biol Chem. 2005;280:15131-40 pubmed..Phylogenetic structure comparisons suggest that the present results are relevant for designing species-specific antibiotics. ..
- Wegscheid B, Hartmann R. In vivo and in vitro investigation of bacterial type B RNase P interaction with tRNA 3'-CCA. Nucleic Acids Res. 2007;35:2060-73 pubmed..We conclude that the observed in vivo defects upon disruption of the CCA interaction are either due to a global deceleration in ptRNA maturation or severe inhibition of 5'-maturation for a ptRNA subset. ..
- Wassmann M, Moeller R, Rabbow E, Panitz C, Horneck G, Reitz G, et al. Survival of spores of the UV-resistant Bacillus subtilis strain MW01 after exposure to low-earth orbit and simulated martian conditions: data from the space experiment ADAPT on EXPOSE-E. Astrobiology. 2012;12:498-507 pubmed publisher..subtilis MW01 in the harsh environments of outer space and the martian surface. ..
- Hoffmann T, Wensing A, Brosius M, Steil L, Volker U, Bremer E. Osmotic control of opuA expression in Bacillus subtilis and its modulation in response to intracellular glycine betaine and proline pools. J Bacteriol. 2013;195:510-22 pubmed publisher..subtilis mutant that was unable to synthesize proline in response to osmotic stress. Collectively, our data suggest that the intracellular solute pool is a key determinant for the osmotic control of opuA expression...
- Stein T, Düsterhus S, Stroh A, Entian K. Subtilosin production by two Bacillus subtilis subspecies and variance of the sbo-alb cluster. Appl Environ Microbiol. 2004;70:2349-53 pubmed..subtilis strains ATCC 6633 and 168 were found to be 47 and 45 bp upstream of the sbo start codon, respectively. Our results provide insight into the incipient evolutionary divergence of the two B. subtilis subspecies. ..
- Reents H, Gruner I, Harmening U, Böttger L, Layer G, Heathcote P, et al. Bacillus subtilis Fnr senses oxygen via a [4Fe-4S] cluster coordinated by three cysteine residues without change in the oligomeric state. Mol Microbiol. 2006;60:1432-45 pubmed..The clear differences in the localization and coordination of the [4Fe-4S] cluster and in the organization of the oligomeric state between Escherichia coli and B. subtilis Fnr indicate differences in their mode of action. ..
- Heydenreich B, Bellinghausen I, Konig B, Becker W, Grabbe S, Petersen A, et al. Gram-positive bacteria on grass pollen exhibit adjuvant activity inducing inflammatory T cell responses. Clin Exp Allergy. 2012;42:76-84 pubmed publisher..Similar to LPS, supernatants of homogenized Gram-positive bacteria may serve as adjuvants by augmenting DC maturation and inflammatory Th1, Th2 and Th17 responses helping to initiate allergic immune responses. ..
- Tadesse S, Mascarenhas J, K sters B, Hasilik A, Graumann P. Genetic interaction of the SMC complex with topoisomerase IV in Bacillus subtilis. Microbiology. 2005;151:3729-37 pubmed publisher..The data also show that the SMC protein has a dual function, in chromosome supercoiling and in active segregation...
- GRUNEBERG H, Oschmann C, Dunya S, Ulrichs C. Improving green roofs and rail road greening systems using Bacillus subtilis and Lactobacillus ssp. Commun Agric Appl Biol Sci. 2006;71:121-30 pubmed..The rapid growth of plants can be influenced by the application of vinasse as additional nutrient solution (potash (K) source) or nutrient enriched substrate. ..
- Mäder U, Schmeisky A, Flórez L, Stülke J. SubtiWiki--a comprehensive community resource for the model organism Bacillus subtilis. Nucleic Acids Res. 2012;40:D1278-87 pubmed publisher..Today, SubtiWiki can be regarded as one of the most complete inventories of knowledge on a living organism in one single resource. ..
- Nguyen H, Schumann W. Establishment of an experimental system allowing immobilization of proteins on the surface of Bacillus subtilis cells. J Biotechnol. 2006;122:473-82 pubmed..It turned out that the highest activity was measured with a spacer length of 123 amino acid residues. ..
- Palm G, Khanh Chi B, Waack P, Gronau K, Becher D, Albrecht D, et al. Structural insights into the redox-switch mechanism of the MarR/DUF24-type regulator HypR. Nucleic Acids Res. 2012;40:4178-92 pubmed publisher..Since hypochloric acid is released by activated macrophages, related HypR-like regulators could function to protect pathogens against the host immune defense...
- Srinivasan V, Rajendran C, Sousa F, Melo A, Saraiva L, Pereira M, et al. Structure at 1.3 A resolution of Rhodothermus marinus caa(3) cytochrome c domain. J Mol Biol. 2005;345:1047-57 pubmed
- Bramkamp M. The putative Bacillus subtilis L,D-transpeptidase YciB is a lipoprotein that localizes to the cell poles in a divisome-dependent manner. Arch Microbiol. 2010;192:57-68 pubmed publisher..Evidence is shown that YciB localizes to the cell poles. YciB localization depends on the existence of a mature divisome, suggesting that L,D-transpeptidases are, like penicillin-binding proteins, part of the divisome. ..
- Horneck G, Moeller R, Cadet J, Douki T, Mancinelli R, Nicholson W, et al. Resistance of bacterial endospores to outer space for planetary protection purposes--experiment PROTECT of the EXPOSE-E mission. Astrobiology. 2012;12:445-56 pubmed publisher..The data demonstrate the high chance of survival of spores on a Mars mission, if protected against solar irradiation. These results will have implications for planetary protection considerations. ..
- Kempf B, Bremer E. OpuA, an osmotically regulated binding protein-dependent transport system for the osmoprotectant glycine betaine in Bacillus subtilis. J Biol Chem. 1995;270:16701-13 pubmed..Physical and genetic mapping experiments allowed the positioning the opuA operon at 25 degrees on the genetic map of B. subtilis. ..
- Schnorpfeil M, Janausch I, Biel S, Kroger A, Unden G. Generation of a proton potential by succinate dehydrogenase of Bacillus subtilis functioning as a fumarate reductase. Eur J Biochem. 2001;268:3069-74 pubmed..The Deltapsi generated by fumarate reduction is suggested to stem from menaquinol:fumarate reductase functioning in a redox half-loop. ..
- Wegscheid B, Condon C, Hartmann R. Type A and B RNase P RNAs are interchangeable in vivo despite substantial biophysical differences. EMBO Rep. 2006;7:411-7 pubmed
- Borriss R, Porwollik S, Schroeter R. The 52 degrees-55 degrees segment of the Bacillus subtilis chromosome: a region devoted to purine uptake and metabolism, and containing the genes cotA, gabP and guaA and the pur gene cluster within a 34960 bp nucleotide sequence. Microbiology. 1996;142 ( Pt 11):3027-31 pubmed..9 kDa protein of Escherichia coli), yecA (amino acid permease) and yecB (adenine deaminase) were similar to proteins in data banks. ..
- Defeu Soufo H, Graumann P. Bacillus subtilis actin-like protein MreB influences the positioning of the replication machinery and requires membrane proteins MreC/D and other actin-like proteins for proper localization. BMC Cell Biol. 2005;6:10 pubmed..The functional dependence on MreB of the localization of the replication machinery suggests that the replisome is not anchored at the cell centre, but is positioned in a dynamic manner. ..
- Bramkamp M, Emmins R, Weston L, Donovan C, Daniel R, Errington J. A novel component of the division-site selection system of Bacillus subtilis and a new mode of action for the division inhibitor MinCD. Mol Microbiol. 2008;70:1556-69 pubmed publisher..The results support a model in which the main function of the Min system lies in allowing only a single round of division per cell cycle, and that MinCD acts at multiple levels to prevent inappropriate division. ..
- Soppa J, Kobayashi K, Noirot Gros M, Oesterhelt D, Ehrlich S, Dervyn E, et al. Discovery of two novel families of proteins that are proposed to interact with prokaryotic SMC proteins, and characterization of the Bacillus subtilis family members ScpA and ScpB. Mol Microbiol. 2002;45:59-71 pubmed
- Gruegelsiepe H, Willkomm D, Goudinakis O, Hartmann R. Antisense inhibition of Escherichia coli RNase P RNA: mechanistic aspects. Chembiochem. 2003;4:1049-56 pubmed
- Le A, Schumann W. The Spo0E phosphatase of Bacillus subtilis is a substrate of the FtsH metalloprotease. Microbiology. 2009;155:1122-32 pubmed publisher..When a mutant Spo0A was produced that was active in the absence of phosphorylation, spores were formed at a normal rate in an ftsH knockout, indicating that ftsH is needed only during phase 0...
- Rhiel E, Flükiger K, Wehrli C, Erni B. The mannose transporter of Escherichia coli K12: oligomeric structure, and function of two conserved cysteines. Biol Chem Hoppe Seyler. 1994;375:551-9 pubmed..Two cysteines in IICMan and IIDMan which are conserved in the homologous subunits of the fructose transporter of Bacillus subtilis and of sorbose transporter of Klebsiella pneumoniae are not necessary for phosphotransferase function. ..
- Homuth G, Masuda S, Mogk A, Kobayashi Y, Schumann W. The dnaK operon of Bacillus subtilis is heptacistronic. J Bacteriol. 1997;179:1153-64 pubmed..Blocking transcription of the suboperon from the upstream heat-inducible promoter did not impair growth and viability at high temperatures. ..
- Pop O, Westermann M, Volkmer Engert R, Schulz D, Lemke C, Schreiber S, et al. Sequence-specific binding of prePhoD to soluble TatAd indicates protein-mediated targeting of the Tat export in Bacillus subtilis. J Biol Chem. 2003;278:38428-36 pubmed..These features suggest that TatA interacts prior to membrane integration with its pre-protein substrate and could therefore assist targeting of twin-arginine pre-proteins. ..
- Vater J, Wilde C, Kell H. In situ detection of the intermediates in the biosynthesis of surfactin, a lipoheptapeptide from Bacillus subtilis OKB 105, by whole-cell cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in combination with mutant ana. Rapid Commun Mass Spectrom. 2009;23:1493-8 pubmed publisher..Our work highlights the applicability and the potential of whole-cell MALDI-TOFMS as an innovative efficient tool for the analysis of intermediate steps of biosynthetic pathways. ..
- Zenhom M, Hyder A, de Vrese M, Heller K, Roeder T, Schrezenmeir J. Peptidoglycan recognition protein 3 (PglyRP3) has an anti-inflammatory role in intestinal epithelial cells. Immunobiology. 2012;217:412-9 pubmed publisher..PGlyRP3 is also stimulated by PGN and has, in contrast to activation of the TLR pathway, an anti-inflammatory effect. ..
- Bacher A, Eberhardt S, Eisenreich W, Fischer M, Herz S, Illarionov B, et al. Biosynthesis of riboflavin. Vitam Horm. 2001;61:1-49 pubmed..The enzymes of the riboflavin pathway are potential targets for antibacterial agents. ..
- Troeschel S, Thies S, Link O, Real C, Knops K, Wilhelm S, et al. Novel broad host range shuttle vectors for expression in Escherichia coli, Bacillus subtilis and Pseudomonas putida. J Biotechnol. 2012;161:71-9 pubmed publisher..subtilis and cutinase from the eukaryotic fungus Fusarium solani pisi in three different host strains. Additionally, we report here the construction of a T7 RNA polymerase-based expression strain of P. putida. ..
- Schleicher E, Hessling B, Illarionova V, Bacher A, Weber S, Richter G, et al. Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy. FEBS J. 2005;272:1855-66 pubmed..This study provides the basis for future time-resolved FT-IR studies which are aimed at an elucidation of a detailed molecular picture of the light-driven DNA repair process. ..
- Grundmann F, Kaiser M, Schiell M, Batzer A, Kurz M, Thanwisai A, et al. Antiparasitic chaiyaphumines from entomopathogenic Xenorhabdus sp. PB61.4. J Nat Prod. 2014;77:779-83 pubmed publisher..Chaiyaphumine A (1) showed good activity against Plasmodium falciparum (IC50 of 0.61 ?M), the causative agent of malaria, and was active against other protozoal tropical disease causing agents. ..
- Wetzstein M, Volker U, Dedio J, Löbau S, Zuber U, Schiesswohl M, et al. Cloning, sequencing, and molecular analysis of the dnaK locus from Bacillus subtilis. J Bacteriol. 1992;174:3300-10 pubmed..The biological property of this inverted repeat as a putative key element in the induction of heat shock genes is discussed. The dnaK locus was mapped at about 223 degrees on the B. subtilis genetic map. ..
- Marahiel M, Nakano M, Zuber P. Regulation of peptide antibiotic production in Bacillus. Mol Microbiol. 1993;7:631-6 pubmed
- Fuchs S, Jaskolla T, Bochmann S, Kötter P, Wichelhaus T, Karas M, et al. Entianin, a novel subtilin-like lantibiotic from Bacillus subtilis subsp. spizizenii DSM 15029T with high antimicrobial activity. Appl Environ Microbiol. 2011;77:1698-707 pubmed publisher..Remarkably, S-entianin and S-subtilin showed considerable autoinduction activity, clearly demonstrating that autoinduction and antibiotic activity underlie different molecular mechanisms. ..
- Zainuddin E, Jansen R, Nimtz M, Wray V, Preisitsch M, Lalk M, et al. Lyngbyazothrins A-D, antimicrobial cyclic undecapeptides from the cultured Cyanobacterium lyngbya sp. J Nat Prod. 2009;72:1373-8 pubmed publisher..It seems that the acyl residue at C-5 of the Aound unit plays an important role in antimicrobial activity. ..
- Rudolph J, Tolliday N, Schmitt C, Schuster S, Oesterhelt D. Phosphorylation in halobacterial signal transduction. EMBO J. 1995;14:4249-57 pubmed..The mechanism of chemo- and phototactic signal transduction in the Archaeon H.salinarium, therefore, is similar to the two-component signaling system known from chemotaxis in the eubacterium E.coli...
- Brutsche S, Braun V. SigX of Bacillus subtilis replaces the ECF sigma factor fecI of Escherichia coli and is inhibited by RsiX. Mol Gen Genet. 1997;256:416-25 pubmed..It is not known which promoters are recognized by SigX in B. subtilis. SigX may be involved in the regulation of iron metabolism, as evidenced by its activity in E. coli. ..
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