Experts and Doctors on arteriosclerosis in Austria

Summary

Locale: Austria
Topic: arteriosclerosis

Top Publications

  1. Schoder M, Cartes Zumelzu F, Grabenwoger M, Cejna M, Funovics M, Krenn C, et al. Elective endovascular stent-graft repair of atherosclerotic thoracic aortic aneurysms: clinical results and midterm follow-up. AJR Am J Roentgenol. 2003;180:709-15 pubmed
    ..92) and between the 2- and 3-year follow-ups (mean, -0.4 mL, p = 0.68). Endovascular treatment of atherosclerotic thoracic aortic aneurysms may result in a substantial reduction of the aneurysm sac in patients without endoleaks. ..
  2. Scharnagl H, März W. New lipid-lowering agents acting on LDL receptors. Curr Top Med Chem. 2005;5:233-42 pubmed
    ..Although these actions are not primary targets of the compounds discussed here, it is interesting that drugs inducing the LDL-R usually also lower TG and, in the case of HMGRI, increase HDL-C. ..
  3. Utermann G. The mysteries of lipoprotein(a). Science. 1989;246:904-10 pubmed
    ..Though of high theoretical and practical interest, many aspects of the metabolism, function, evolution, and regulation of plasma concentrations of Lp(a) are presently unknown, controversial, or mysterious. ..
  4. Bonatti J, Hangler H, Oturanlar D, Posch L, Müller L, Voelckel W, et al. Beating heart axillocoronary bypass for management of the untouchable ascending aorta in coronary artery bypass grafting. Eur J Cardiothorac Surg. 1999;16 Suppl 2:S18-23 pubmed
  5. Huber J, Vales A, Mitulovic G, Blumer M, Schmid R, Witztum J, et al. Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions. Arterioscler Thromb Vasc Biol. 2002;22:101-7 pubmed
    ..In addition to oxidized lipoproteins, oxidized MVs and apoptotic blebs may play an important role in chronic inflammatory diseases, such as atherosclerosis...
  6. Schillinger M, Exner M, Mlekusch W, Domanovits H, Huber K, Mannhalter C, et al. Heme oxygenase-1 gene promoter polymorphism is associated with abdominal aortic aneurysm. Thromb Res. 2002;106:131-6 pubmed
    ..This suggests that short alleles, and thus, facilitated upregulation of HO-1, may be a protective anti-inflammatory factor against the development of AAA. ..
  7. Gruber F, Hufnagl P, Hofer Warbinek R, Schmid J, Breuss J, Huber Beckmann R, et al. Direct binding of Nur77/NAK-1 to the plasminogen activator inhibitor 1 (PAI-1) promoter regulates TNF alpha -induced PAI-1 expression. Blood. 2003;101:3042-8 pubmed
    ..High expression levels of Nur77 and its colocalization with PAI-1 in atherosclerotic tissues indicate that the described mechanism for PAI-1 regulation may also be operative in vivo. ..
  8. Marculescu R, Mlekusch W, Exner M, Sabeti S, Michor S, Rumpold H, et al. Interleukin-1 cluster combined genotype and restenosis after balloon angioplasty. Thromb Haemost. 2003;90:491-500 pubmed
    ..This remarkable gene dose-dependent association emphasizes the advantage of considering combinations of genetic markers rather that isolated polymorphisms in the analysis of multifactorial vascular disease. ..
  9. Schillinger M, Exner M, Mlekusch W, Amighi J, Sabeti S, Schlager O, et al. Serum albumin predicts cardiac adverse events in patients with advanced atherosclerosis - interrelation with traditional cardiovascular risk factors. Thromb Haemost. 2004;91:610-8 pubmed

More Information

Publications14

  1. Pfister G, Stroh C, Perschinka H, Kind M, Knoflach M, Hinterdorfer P, et al. Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy. J Cell Sci. 2005;118:1587-94 pubmed
    ..The relevance of our findings with respect to the role of HSP60 in atherogenesis is discussed. ..
  2. Mueller T, Marschon R, Dieplinger B, Haidinger D, Gegenhuber A, Poelz W, et al. Factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations are not associated with chronic limb ischemia: the Linz Peripheral Arterial Disease (LIPAD) study. J Vasc Surg. 2005;41:808-15 pubmed
    ..Thus, there is no indication that of one of these mutations may be a risk factor for chronic limb ischemia. However, the role of these mutations in acute limb ischemia remains to be clarified. ..
  3. Exner M, Raith M, Holzer G, Gmeiner B, Wagner O, Kapiotis S. Anti-inflammatory mechanisms of the Tibetan herbal preparation Padma 28 in the vessel wall. Forsch Komplementmed. 2006;13 Suppl 1:13-7 pubmed
    ..These properties may be responsible for its anti-atherosclerotic effects in peripheral arterial occlusive disease. ..
  4. Fickert P, Moustafa T, Trauner M. Primary sclerosing cholangitis--the arteriosclerosis of the bile duct?. Lipids Health Dis. 2007;6:3 pubmed
    ..This hypothesis should stimulate translational research to facilitate the search for novel treatment strategies for both diseases. ..
  5. Rosenhek R, Baumgartner H. Aortic sclerosis, aortic stenosis and lipid-lowering therapy. Expert Rev Cardiovasc Ther. 2008;6:385-90 pubmed publisher
    ..Lipid-lowering therapy with statins can, therefore, currently only be recommended in this subgroup of patients with AS. ..