Experts and Doctors on animals in Brazil

Summary

Locale: Brazil
Topic: animals

Top Publications

  1. Watanabe L, Nirthanan S, Rajaseger G, Polikarpov I, Kini R, Arni R. Crystallization and preliminary X-ray analysis of bucain, a novel toxin from the Malayan krait Bungarus candidus. Acta Crystallogr D Biol Crystallogr. 2002;58:1879-81 pubmed
    ..Attempts to solve these structures by molecular-replacement methods have not been successful and a heavy-atom derivative search has been initiated...
  2. Epiphanio S, Sinhorini I, Catão Dias J. Pathology of toxoplasmosis in captive new world primates. J Comp Pathol. 2003;129:196-204 pubmed
    ..4%), interstitial pneumonia (90.3%) and necrotic splenitis (71.4%). The gross post-mortem changes in cebids were more variable than those observed in callitrichids, a fact that may complicate the diagnosis of toxoplasmosis in cebids...
  3. Minatel E, Neto H, Marques M. Acetylcholine receptor distribution and synapse elimination at the developing neuromuscular junction of mdx mice. Muscle Nerve. 2003;28:561-9 pubmed
    ..7% controls, n = 200 per group). These results show that dystrophic fibers achieve single innervation earlier, perhaps because dystrophin or a normal cytoskeletal complex is implicated in this phenomenon. ..
  4. Garcia E, Machado E, Azambuja P. Inhibition of hemocyte microaggregation reactions in Rhodnius prolixus larvae orally infected with Trypanosoma rangeli. Exp Parasitol. 2004;107:31-8 pubmed
    ..rangeli, and that oral infection with this protozoan inhibits the release of arachidonic acid. ..
  5. Cardillo J, Farah M, Mitre J, Morales P, Costa R, Melo L, et al. An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy. Br J Ophthalmol. 2004;88:1201-5 pubmed
    ..Additional studies to add knowledge to these initial findings and to clarify the potential of the codrug device for the treatment of human PVR are warranted. ..
  6. Meyre Silva C, Yunes R, Schlemper V, Campos Buzzi F, Cechinel Filho V. Analgesic potential of marrubiin derivatives, a bioactive diterpene present in Marrubium vulgare (Lamiaceae). Farmaco. 2005;60:321-6 pubmed
    ..Marrubiinic acid showed better activity and excellent yield, and its analgesic effect was confirmed in other experimental models of pain in mice, suggesting its possible use as a model to obtain new and potent analgesic agents...
  7. Both F, Meneghini L, Kerber V, Henriques A, Elisabetsky E. Role of glutamate and dopamine receptors in the psychopharmacological profile of the indole alkaloid psychollatine. J Nat Prod. 2006;69:342-5 pubmed
    ..01), and chlorpromazine (4 mg/kg) (P < 0.01) attenuated apomorphine-induced climbing behavior. The present results strongly support the involvement of NMDA glutamate receptors in the mode of action of psychollatine (1)...
  8. Silva Freitas E, Fagian M, da Cruz Höfling M. Effects of veratrine and veratridine on oxygen consumption and electrical membrane potential of isolated rat skeletal muscle and liver mitochondria. Toxicon. 2006;47:780-7 pubmed
    ..Identification of the specific respiratory chain targets involved should provide a better understanding of the molecular mechanisms of the toxicity of these agents. ..
  9. De Stefano L, Matsubara L, Matsubara B. Myocardial dysfunction with increased ventricular compliance in volume overload hypertrophy. Eur J Heart Fail. 2006;8:784-9 pubmed
    ..These haemodynamic features help to explain the long-term compensatory phase of chronic volume overload before transition to overt congestive heart failure. ..

More Information

Publications599 found, 100 shown here

  1. Martino H, Martin B, Weaver C, Bressan J, Esteves E, Costa N. Zinc and iron bioavailability of genetically modified soybeans in rats. J Food Sci. 2007;72:S689-95 pubmed
    ..Whole body 59Fe retention from UFV-116 was lower (P < 0.05) than from OCEPAR-19. Zinc and iron bioavailability was lower for UFV-116, possibly due to its higher content of antinutrient factors, especially phytate. ..
  2. Moura Costa L, Bahia R, Carminati R, Vale V, Paule B, Portela R, et al. Evaluation of the humoral and cellular immune response to different antigens of Corynebacterium pseudotuberculosis in Canindé goats and their potential protection against caseous lymphadenitis. Vet Immunol Immunopathol. 2008;126:131-41 pubmed publisher
    ..These results demonstrate the immunogenic potential of the attenuated T1 strain in the development of a vaccine against caseous lymphadenitis in goats...
  3. Guimarães F, Abud A, Oliveira S, Oliveira C, Cesar B, Andrade L, et al. Stimulation of lymphocyte anti-melanoma activity by co-cultured macrophages activated by complex homeopathic medication. BMC Cancer. 2009;9:293 pubmed publisher
    ..In addition, they are attractive combination-therapy candidates, which may enhance the efficacy of conventional medicines by improving the immune response against tumor cells. ..
  4. Bonfleur M, Vanzela E, Ribeiro R, de Gabriel Dorighello G, de França Carvalho C, Collares Buzato C, et al. Primary hypercholesterolaemia impairs glucose homeostasis and insulin secretion in low-density lipoprotein receptor knockout mice independently of high-fat diet and obesity. Biochim Biophys Acta. 2010;1801:183-90 pubmed publisher
    ..This represents an additional risk factor for diabetes and atherosclerosis in primary hypercholesterolaemia. ..
  5. Correa Netto C, Teixeira Araujo R, Aguiar A, Melgarejo A, De Simone S, Soares M, et al. Immunome and venome of Bothrops jararacussu: a proteomic approach to study the molecular immunology of snake toxins. Toxicon. 2010;55:1222-35 pubmed publisher
    ..These results also reinforce the importance of neutralizing the highly toxic proteins inclusive those with low immunogenicity in commercial antivenom production to obtain a highly protective serum against snake venoms. ..
  6. Simões R, Satrapa R, Rosa F, Piagentini M, Castilho A, Ereno R, et al. Ovulation rate and its relationship with follicle diameter and gene expression of the LH receptor (LHR) in Nelore cows. Theriogenology. 2012;77:139-47 pubmed publisher
    ..We concluded that ovulatory capacity in Nelore cattle was related to increased follicular diameter and expression of the LHR gene in granulosa cells. ..
  7. Carvalho A, Gomes V. Plant defensins and defensin-like peptides - biological activities and biotechnological applications. Curr Pharm Des. 2011;17:4270-93 pubmed
    ..This review will cover the biological activities and roles of plant defensins and will focus on their application in the field of biotechnology. ..
  8. Silva E, Masui D, Furriel R, McNamara J, Barrabin H, Scofano H, et al. Identification of a crab gill FXYD2 protein and regulation of crab microsomal Na,K-ATPase activity by mammalian FXYD2 peptide. Biochim Biophys Acta. 2012;1818:2588-97 pubmed publisher
    ..These findings confirm the presence of an FXYD2 peptide in the crab gill Na,K-ATPase and demonstrate that this peptide plays an important role in regulating enzyme activity. ..
  9. Rasia Filho A, Dalpian F, Menezes I, Brusco J, Moreira J, Cohen R. Dendritic spines of the medial amygdala: plasticity, density, shape, and subcellular modulation by sex steroids. Histol Histopathol. 2012;27:985-1011 pubmed publisher
    ..Various working hypotheses are raised from these experimental data and reveal the MePD as a relevant region to study the effects of sex steroids in the rat brain. ..
  10. Samia D, Nomura F, Blumstein D. Do animals generally flush early and avoid the rush? A meta-analysis. Biol Lett. 2013;9:20130016 pubmed publisher
  11. Silva D, Cortez C, Silva C, Missailidis S. A fluorescent spectroscopy and modelling analysis of anti-heparanase aptamers-serum protein interactions. J Photochem Photobiol B. 2013;127:68-77 pubmed publisher
    ..suggest that the primary binding site in both aptamers is located closer to the tryptophan residue in sub domain IIA. It is likely that both aptamers are competing for the same primary site in albumin. ..
  12. Ribeiro A, Palomino Z, Lima M, Souza L, Ferreira D, Pesquero J, et al. Characterization of the renal renin-angiotensin system in transgenic mice that express rat tonin. J Renin Angiotensin Aldosterone Syst. 2015;16:947-55 pubmed publisher
    ..Angiotensin 1-7 (Ang(1-7)) and Ang I levels were significantly lower in the TGM`(rTon). We suggest that the environment of tonin abundance may increase N-domain ACE activity liberated by a secretase able to cleave somatic ACE. ..
  13. Damante C, Ducati P, Ferreira R, Salmeron S, Zangrando M, de Rezende M, et al. In vitro evaluation of adhesion/proliferation of human gingival fibroblasts on demineralized root surfaces by toluidine blue O in antimicrobial photodynamic therapy. Photodiagnosis Photodyn Ther. 2016;13:303-307 pubmed publisher
    ..66, p<0.05) compared to PDT4 (2.2) and C (1.33). PDT4 is not as aggressive as CA for enamel. However, dentin demineralized promoted by PDT4 does not stimulate HGF adhesion and proliferation as CA. ..
  14. Zugaib J, Ceballos C, Leão R. High doses of salicylate reduces glycinergic inhibition in the dorsal cochlear nucleus of the rat. Hear Res. 2016;332:188-198 pubmed publisher
    ..So, the mechanisms of salicylate-induced tinnitus are probably more complex than simple changes in the neuronal firing and basal synaptic transmission in the DCN. ..
  15. Mourão A, Moreira M, Melo A, Lopes P, Rebelo A, Rosa D, et al. Does the median preoptic nucleus contribute to sympathetic hyperactivity in spontaneously hypertensive rats?. Auton Neurosci. 2016;195:29-33 pubmed publisher
    ..Furthermore, our data suggest the MnPO involvement in the increased sympathetic outflow and consequent arterial hypertension observed in SHRs. ..
  16. Aparecida Silva Barbosa A, Freitas Versiani A, Fonseca da Cunha Sousa L, Silva de Miranda A, Gasparini M, Brant F, et al. Role of the suppressor of cytokine signaling 2 (SOCS2) during meningoencephalitis caused by Bovine herpesvirus 5 (BoHV-5). Comp Immunol Microbiol Infect Dis. 2016;47:26-31 pubmed publisher
    ..Taken together, our study provides an insight into the role of SOCS2 in modulating the immune response to BoHV-5 infection. ..
  17. Beaudry F, Iwanicki T, Mariluz B, Darnet S, Brinkmann H, Schneider P, et al. The non-visual opsins: eighteen in the ancestor of vertebrates, astonishing increase in ray-finned fish, and loss in amniotes. J Exp Zool B Mol Dev Evol. 2017;328:685-696 pubmed publisher
    ..Most non-visual opsins have been named without the benefit of a phylogenetic perspective and, accordingly, major revisions are proposed...
  18. Almeida Toledo L, Foresti F, Daniel M, Toledo Filho S. Sex chromosome evolution in fish: the formation of the neo-Y chromosome in Eigenmannia (Gymnotiformes). Chromosoma. 2000;109:197-200 pubmed
  19. Ventrucci G, Mello M, Gomes Marcondes M. Effect of a leucine-supplemented diet on body composition changes in pregnant rats bearing Walker 256 tumor. Braz J Med Biol Res. 2001;34:333-8 pubmed
    ..These data suggest that the leucine-supplemented diet had a beneficial effect, probably attenuating body wasting...
  20. Colla A, Machado D, Bettio L, Colla G, Magina M, Brighente I, et al. Involvement of monoaminergic systems in the antidepressant-like effect of Eugenia brasiliensis Lam. (Myrtaceae) in the tail suspension test in mice. J Ethnopharmacol. 2012;143:720-31 pubmed publisher
    ..uniflora is used for the treatment of symptoms related to depression and mood disorders, and is used in Brazil by the Guarani Indians as a tonic stimulant...
  21. Cyrino L, Araújo A, Joazeiro P, Vicente C, Giorgio S. In vivo and in vitro Leishmania amazonensis infection induces autophagy in macrophages. Tissue Cell. 2012;44:401-8 pubmed publisher
  22. Martins C, Alves L, Mamprim A. Effect of plant extracts and a disinfectant on biological parameters and pathogenicity of the fungus Beauveria bassiana (Bals.) Vuill. (Ascomycota: Cordycipitaceae). Braz J Biol. 2016;76:420-7 pubmed publisher
    ..5 RC, and above 80% for the extracts. Thus, the results showed that all the extracts and Peroxitane at RC 0.5 are compatible with the fungus B. bassiana Unioeste 4, however only the extracts had a low impact on inoculum potential. ..
  23. Pinheiro M, Joazeiro P, Mora O, Toledo O. Ultrastructural and immunohistochemical analysis of proteoglycans in mouse pubic symphysis. Cell Biol Int. 2003;27:647-55 pubmed
    ..The data thus obtained on the localization and identification of pubic symphyseal proteoglycans in virgin mice may be useful in the study of structural modifications that occur throughout pregnancy...
  24. Luiz R, Jordão B, da Eira A, Ribeiro L, Mantovani M. Mechanism of anticlastogenicity of Agaricus blazei Murill mushroom organic extracts in wild type CHO (K(1)) and repair deficient (xrs5) cells by chromosome aberration and sister chromatid exchange assays. Mutat Res. 2003;528:75-9 pubmed
    ..These results indicate that organic extracts of A. blazei lineage AB97/11 present bio-antimutagenic type protective activity. ..
  25. Branco B, Gaudio P, Margolis T. Epidemiology and molecular analysis of herpes simplex keratitis requiring primary penetrating keratoplasty. Br J Ophthalmol. 2004;88:1285-8 pubmed
    ..It is unlikely that this decline was the result of improved diagnostic accuracy since detection of HSV DNA in corneal buttons with a clinical diagnosis of HSK was similar at the beginning and end of the study period. ..
  26. Xavier M, Silveira F, Demachki S, Ferreira M, do Nascimento J. American tegumentary leishmaniasis: a quantitative analysis of Langerhans cells presents important differences between L. (L.) amazonensis and Viannia subgenus. Acta Trop. 2005;95:67-73 pubmed
    ..Such results confirm the important role of LC in ATL, while suggesting that L. (L.) amazonensis may be a good model for LC studies as APC in ATL, due to its spectral immunological and clinical behavior...
  27. Ecco R, Guedes R, Tury E, Santos H, Perecmanis S. Outbreak of enterocolitic salmonellosis on a wild pig farm. Vet Rec. 2006;158:242-3 pubmed
  28. Santos F, Colus I, Silva M, Vilegas W, Varanda E. Assessment of DNA damage by extracts and fractions of Strychnos pseudoquina, a Brazilian medicinal plant with antiulcerogenic activity. Food Chem Toxicol. 2006;44:1585-9 pubmed
    ..pseudoquina. In high doses, constituents of S. pseudoquina compounds act on DNA, causing breaks and giving rise to micronuclei in the blood cells of treated animals...
  29. Amaral M, Owens K, Elliott J, Fickey C, Schaffer A, Agarwala R, et al. Construction of a river buffalo (Bubalus bubalis) whole-genome radiation hybrid panel and preliminary RH mapping of chromosomes 3 and 10. Anim Genet. 2007;38:311-4 pubmed
  30. de Andrade Pinto A, Barbosa C, Ornellas D, Novaira H, de Souza Menezes J, Ortiga Carvalho T, et al. Thyroid hormones stimulate renal expression of CFTR. Cell Physiol Biochem. 2007;20:83-90 pubmed
    ..05). Analysis of the promoter region of CFTR transfected to IRPTC showed that T(3) (10(-7) M) stimulates the CFTR promoter (38%, n=4, p<0.05). ..
  31. Lima D, Silva A, Aguiar F, Liporoni P, Munin E, Ambrosano G, et al. In vitro assessment of the effectiveness of whitening dentifrices for the removal of extrinsic tooth stains. Braz Oral Res. 2008;22:106-11 pubmed
    ..Among the dentifrices tested, only the Rapid White group differed from the control group, presenting the highest reflectance values. Only the whitening dentifrice Rapid White was effective for the removal of extrinsic stains. ..
  32. Mazzer P, Barbieri C, Mazzer N, Fazan V. Morphologic and morphometric evaluation of experimental acute crush injuries of the sciatic nerve of rats. J Neurosci Methods. 2008;173:249-58 pubmed publisher
    ..The predominant type of lesion produced was axonotmesis. ..
  33. Crosara Alberto D, Inoue R, Costa C. FAK signalling mediates NF-kappaB activation by mechanical stress in cardiac myocytes. Clin Chim Acta. 2009;403:81-6 pubmed publisher
    ..Further studies are needed to elucidate the influence of this signalling pathway on gene transcription regulation, and cardiac myocyte phenotypic changes in response to mechanical stress. ..
  34. Barbosa L, Rall V, Fernandes A, Ushimaru P, da Silva Probst I, Fernandes A. Essential oils against foodborne pathogens and spoilage bacteria in minced meat. Foodborne Pathog Dis. 2009;6:725-8 pubmed publisher
    ..3 and 1.0 were the highest log CFU/g reduction values obtained against tested microorganisms...
  35. Freitas E, Rahal S, Teixeira C, Silva J, Noritomi P, Villela C, et al. Rapid prototyping and inclined plane technique in the treatment of maxillofacial malformations in a fox. Can Vet J. 2010;51:267-70 pubmed
    ..Orthodontic treatment was performed using the inclined plane technique. Virtual 3D models and prototypes of the head were based on computed tomography (CT) image data to assist in diagnosis and treatment. ..
  36. Aléssio A, Santos C, Debbas V, Oliveira L, Haddad R, Annichino Bizzacchi J. Evaluation of mild hyperhomocysteinemia during the development of atherosclerosis in apolipoprotein E-deficient and normal mice. Exp Mol Pathol. 2011;90:45-50 pubmed publisher
    ..Mild HHcy accelerated the development of atherosclerosis in apoE(-/-) mice, and supplementation with B-vitamins is important for prevention of vascular disease, principally in the long term. ..
  37. de Lima Salgado T, Alba Loureiro T, do Nascimento C, Nunes M, Curi R. Molecular mechanisms by which saturated fatty acids modulate TNF-? expression in mouse macrophage lineage. Cell Biochem Biophys. 2011;59:89-97 pubmed publisher
  38. Tonin A, Pimentel V, Da Silva A, de Azevedo M, Souza V, Wolkmer P, et al. Adenosine deaminase activity in serum, erythrocytes and lymphocytes of rats infected with Leptospira icterohaemorrhagiae. Res Vet Sci. 2012;92:197-201 pubmed publisher
    ..05). In conclusion, our results showed that the ADA activity is altered in serum, lymphocytes and erythrocytes in experimental infection by L.icterohaemorrhagiae in rats, concomitantly with hematological parameters. ..
  39. Perry J, Bergamaschi C, Campos R, Andersen M, Montano N, Casarini D, et al. Sympathetic and angiotensinergic responses mediated by paradoxical sleep loss in rats. J Renin Angiotensin Aldosterone Syst. 2011;12:146-52 pubmed publisher
    ..Thus, alterations in the sympathetic system in response to sleep loss may be an important pathway through which hypertension develops. ..
  40. Ferraz K, Sousa Santos O, Neto Neves E, Rizzi E, Muniz J, Gerlach R, et al. Recombinant human matrix metalloproteinase-2 impairs cardiovascular ?-adrenergic responses. Basic Clin Pharmacol Toxicol. 2013;112:103-9 pubmed publisher
    ..Our findings show that rhMMP-2 exerts no major haemodynamic effects in lambs. However, rhMMP-2 impairs the responses elicited by activation of ?-adrenoreceptors...
  41. Rodrigues B, Jorge L, Mostarda C, Rosa K, Medeiros A, Malfitano C, et al. Aerobic exercise training delays cardiac dysfunction and improves autonomic control of circulation in diabetic rats undergoing myocardial infarction. J Card Fail. 2012;18:734-44 pubmed publisher
    ..ET reduced cardiac and peripheral dysfunction and preserved autonomic control in diabetic infarcted rats. Consequently, these changes resulted in improved VO(2)max and survival after MI. ..
  42. Costa A, Silva A, Costa F, Xavier G, Martins T, Labruna M, et al. A survey of ectoparasites infesting urban and rural dogs of Maranhão state, Brazil. J Med Entomol. 2013;50:674-8 pubmed
    ..Further studies are warranted to evaluate canine vector-borne agents in Maranhão, especially because most of the ectoparasites here reported are vectors of major vector-borne diseases, including zoonoses of continental importance...
  43. Postuma F, Gasalla M. Ethogram analysis reveals new body patterning behavior of the tropical arrow squid Doryteuthis plei off the São Paulo Coast. Biol Bull. 2015;229:143-59 pubmed
    ..In conclusion, new basic types of body patterns are described for D. plei. The repertoire of chromatic components reported in the ethogram is, to our knowledge, the first record for D. plei of the Southern Hemisphere. ..
  44. Matias D, Predes D, Niemeyer Filho P, Lopes M, Abreu J, Lima F, et al. Microglia-glioblastoma interactions: New role for Wnt signaling. Biochim Biophys Acta Rev Cancer. 2017;1868:333-340 pubmed publisher
    ..Here, we discuss recent interesting findings that support a role for Wnt signaling pathways in the microglia-glioblastoma crosstalk. ..
  45. Torres Y, Berlinck R, Nascimento G, Fortier S, Pessoa C, de Moraes M. Antibacterial activity against resistant bacteria and cytotoxicity of four alkaloid toxins isolated from the marine sponge Arenosclera brasiliensis. Toxicon. 2002;40:885-91 pubmed
    ..brasiliensis alkaloids suggest a defensive role of arenosclerins and haliclonacyclamine E against microbial infection and/or the action of potential predators at the sponge's natural habitat. ..
  46. Vieira M, Brito G, Belarmino Filho J, Macedo F, Nery E, Cunha F, et al. Use of dexamethasone with mesna for the prevention of ifosfamide-induced hemorrhagic cystitis. Int J Urol. 2003;10:595-602 pubmed
    ..Dexamethasone in combination with mesna was efficient in blocking IFS-induced HC. However, the replacement of last two doses of mesna with saline or all of the mesna doses with dexamethasone did not prevent HC. ..
  47. Guimarães A, Alves E, de Rezende G, Rodrigues M. [Toxocara sp. eggs and Ancylostoma sp. larva in public parks, Brazil]. Rev Saude Publica. 2005;39:293-5 pubmed
    ..Public parks are settings of more potential risk of Toxocara sp. eggs and Ancylostoma sp. infection. Stool parasitology testing of 174 stool samples showed 58% and 23% of Ancylostoma sp and Toxocara sp eggs infection respectively...
  48. Moyses Z, Nakandakari F, Magaldi A. Fluoxetine effect on kidney water reabsorption. Nephrol Dial Transplant. 2008;23:1173-8 pubmed
  49. Bueno M, Brevidelli M, Cocarelli T, Santos G, Ferraz M, Mion D. Reasons for resubmission of research projects to the research ethics committee of a university hospital in São Paulo, Brazil. Clinics (Sao Paulo). 2009;64:831-6 pubmed publisher
  50. Herai R, Yamagishi M. Detection of human interchromosomal trans-splicing in sequence databanks. Brief Bioinform. 2010;11:198-209 pubmed publisher
    ..Our methodology can be applied to 5'-UTR, coding sequences and 3'-UTR in order to find new candidates for a posteriori experimental confirmation. ..
  51. Cândido E, Fávaro W, Montico F, Hetzl A, Cagnon V. Senescence and steroid hormone receptor reactivities in accessory sex glands of elderly rats (Sprague-Dawley) following exogenous hormonal therapy. Tissue Cell. 2012;44:227-37 pubmed publisher
  52. Rolim Filho S, Ribeiro H, de Camargo G, Cardoso D, Aspilcueta Borquis R, Tonhati H, et al. Identification of polymorphisms in the osteopontin gene and their associations with certain semen production traits of water buffaloes in the Brazilian Amazon. Reprod Domest Anim. 2013;48:705-9 pubmed publisher
    ..These results indicate a significance of the osteopontin gene as it seems to exert a substantial influence on the semen production traits of male buffaloes. ..
  53. Marques R, Bernardi J, Dorea J, de Fatima R Moreira M, Malm O. Perinatal multiple exposure to neurotoxic (lead, methylmercury, ethylmercury, and aluminum) substances and neurodevelopment at six and 24 months of age. Environ Pollut. 2014;187:130-5 pubmed publisher
    ..PDI was positively affected by breastfeeding and negatively affected by ethylmercury. Milestone achievements were negatively affected by breast-milk Pb (age of walking) and by HHg (age of talking). ..
  54. Heidor R, Furtado K, Ortega J, de Oliveira T, Tavares P, Vieira A, et al. The chemopreventive activity of the histone deacetylase inhibitor tributyrin in colon carcinogenesis involves the induction of apoptosis and reduction of DNA damage. Toxicol Appl Pharmacol. 2014;276:129-35 pubmed publisher
    ..Induction of apoptosis and reduction of DNA damage are cellular mechanisms that appear to be involved in the chemopreventive activity of TB. ..
  55. Senna S, Torres M, Lopes D, Alheiros Lira M, de Moura D, Pereira V, et al. Moderate physical training attenuates perinatal low-protein-induced spleen lymphocyte apoptosis in endotoxemic adult offspring rats. Eur J Nutr. 2016;55:1113-22 pubmed publisher
    ..Moderate physical training was able to revert the effects of perinatal LP diet on circulation lymphocytes subsets and attenuated splenic lymphocytes apoptosis and plasma TNF-α concentrations. ..
  56. Coelho P, Gil L, Neiva R, Jimbo R, Tovar N, Lilin T, et al. Microrobotized blasting improves the bone-to-textured implant response. A preclinical in vivo biomechanical study. J Mech Behav Biomed Mater. 2016;56:175-182 pubmed publisher
    ..Microrobotized blasting resulted in higher biomechanical fixation of endosteal dental implants and should be considered as an alternative for impant surface manufacturing. ..
  57. Mazur C, Machado R. Detection of contagious pustular dermatitis virus of goats in a severe outbreak. Vet Rec. 1989;125:419-20 pubmed
  58. De Souza W, Motta M. Endosymbiosis in protozoa of the Trypanosomatidae family. FEMS Microbiol Lett. 1999;173:1-8 pubmed
    ..The results obtained show that endosymbiont-containing species of trypanosomatids constitute an excellent model to study basic processes on the endosymbiont-host cell relationship and the origin of new organelles...
  59. Tonussi C, Ferreira S. Tumour necrosis factor-alpha mediates carrageenin-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joints. Pain. 1999;82:81-7 pubmed
  60. Victor J, Fusaro A, Duarte A, Sato M. Preconception maternal immunization to dust mite inhibits the type I hypersensitivity response of offspring. J Allergy Clin Immunol. 2003;111:269-77 pubmed
    ..Maternal immunization to D pteronyssinus seems to protect offspring from the development of allergy. ..
  61. Arruda S, Siqueira E, Souza E. Malanga (Xanthosoma sagittifolium) and purslane (Portulaca oleracea) leaves reduce oxidative stress in vitamin A-deficient rats. Ann Nutr Metab. 2004;48:288-95 pubmed
    ..This study examined the ability of tropical vegetables to reduce oxidative stress induced by vitamin A deficiency...
  62. Guerra Sa R, Castro Borges W, Evangelista E, Kettelhut I, Rodrigues V. Schistosoma mansoni: functional proteasomes are required for development in the vertebrate host. Exp Parasitol. 2005;109:228-36 pubmed
    ..Finally, we present evidence that during experimental schistosomiasis, proteasome inhibitors were able to reduce the number of lung stage schistosomula, reduce the worm burden and consequently decrease the egg output in infected mice. ..
  63. Arruda R, Peotta V, Meyrelles S, Vasquez E. Evaluation of vascular function in apolipoprotein E knockout mice with angiotensin-dependent renovascular hypertension. Hypertension. 2005;46:932-6 pubmed
    ..However, the concurrence of both pathophysiologies does not result in additive effects on the vascular function...
  64. de Azeredo Espin A, Lessinger A. Genetic approaches for studying myiasis-causing flies: molecular markers and mitochondrial genomics. Genetica. 2006;126:111-31 pubmed
  65. Hollanda L, Lima C, Cunha A, Albuquerque D, Vassallo J, Ozelo M, et al. An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis. Nat Genet. 2006;38:807-12 pubmed
    ..Moreover, this is the first study to indicate that a germline splicing mutation does not lead to leukemia in the absence of other cooperating events, such as Down syndrome. ..
  66. Barros K, Xavier R, Abreu G, Martinez C, Ribeiro M, Gambero A, et al. Soybean and fish oil mixture increases IL-10, protects against DNA damage and decreases colonic inflammation in rats with dextran sulfate sodium (DSS) colitis. Lipids Health Dis. 2010;9:68 pubmed publisher
    ..Soybean and fish oil mixture may be effective in improving colonic injury and DNA damage, and it could be an important complementary therapy in UC to reduce the use of anti-inflammatory drugs and prevent colorectal cancer. ..
  67. Rosa Neto J, Lira F, Venancio D, Cunha C, Oyama L, Pimentel G, et al. Sleep deprivation affects inflammatory marker expression in adipose tissue. Lipids Health Dis. 2010;9:125 pubmed publisher
    ..The inflammatory response was diminished in both depots of adipose tissue, with increased IL-6 levels in RPAT and decreased TNF-? protein concentrations in MEAT and increased levels of corticosterone in serum. ..
  68. Silva L, Teixeira F, Ortega J, Zárate L, Nobre C. Improvement in the prediction of the translation initiation site through balancing methods, inclusion of acquired knowledge and addition of features to sequences of mRNA. BMC Genomics. 2011;12 Suppl 4:S9 pubmed publisher
  69. Jansen Amorim A, Fiorani M, Gattass R. GABA inactivation of area V4 changes receptive-field properties of V2 neurons in Cebus monkeys. Exp Neurol. 2012;235:553-62 pubmed publisher
  70. Lallo M, Calábria P, Milanelo L. Encephalitozoon and Enterocytozoon (Microsporidia) spores in stool from pigeons and exotic birds: microsporidia spores in birds. Vet Parasitol. 2012;190:418-22 pubmed publisher
    ..bieneusi EpbA (AF076040). No fecal sample contained more than one type of microsporidian species. This study implicates exotic birds and pigeons as potential sources of microsporidia infection for humans living in urban areas. ..
  71. Commodaro A, Pedregosa J, Peron J, Brandão W, Rizzo L, Bueno V. The imbalance between Treg and Th17 cells caused by FTY720 treatment in skin allograft rejection. Clinics (Sao Paulo). 2012;67:805-13 pubmed
    ..To further understand the process of graft rejection/acceptance, we evaluated skin allograft survival and associated events after FTY720 treatment...
  72. Viana L, Winck G, Coelho C, Flausino W, Duarte Rocha C. A new species of Caryospora Léger, 1904 (Apicomplexa: Eimeriidae) from the snake Philodryas olfersii Lichtenstein (Colubridae) from a coastal habitat in Brazil. Syst Parasitol. 2013;85:195-9 pubmed publisher
    ..Stieda body present, 3.2 × 1.3 ?m, sub-Stieda body present, homogeneous, larger than Stieda body, 4.5 × 1.7 ?m. Sporozoites are inserted in a bulky sporocyst residuum...
  73. Freitas H, Ferraz G, Ferreira G, Ribeiro Resende V, Chiarini L, do Nascimento J, et al. Glutathione-Induced Calcium Shifts in Chick Retinal Glial Cells. PLoS ONE. 2016;11:e0153677 pubmed publisher
  74. de Oliveira J, Nonato F, Zafred R, Leite N, Ruiz A, de Carvalho J, et al. Evaluation of anti-inflammatory effect of derivative (E)-N-(4-bromophenyl)-2-(thiophen-2-ylmethylene)-thiosemicarbazone. Biomed Pharmacother. 2016;80:388-392 pubmed publisher
    ..This suggests an action on the early mediators of inflammation. The paw edema assay induced by compound 48/80 confirmed our hypothesis indicating action of the compound via histamine. ..
  75. Ribeiro Neto J, Pinto M, Ferreira V, Tibúrcio J, Varotti F, Azevedo D, et al. Larvicidal activity of vegetable oils and esterified compounds against Culex quinquefasciatus (Diptera: Culicidae). Ecotoxicol Environ Saf. 2017;143:57-61 pubmed publisher
    ..Cytotoxicity of FAMEs compounds was assessed with the HeLa human cell line and no effect was observed. ..
  76. Amorim A, Carrington M, Miles M, Barker D, de Almeida M. Identification of the C-terminal region of 70 kDa heat shock protein from Leishmania (Viannia) braziliensis as a target for the humoral immune response. Cell Stress Chaperones. 1996;1:177-87 pubmed
    ..amazonensis-infected individuals. Despite a relatively high cross-reactivity with VL sera, the enhanced humoral response of MCL as compared with CL patients might be interesting for studies on disease aggravation. ..
  77. Reis M, de Faria D, dos Santos I, Amaral M, Marsaioli A. Byrsonic acid--the clue to floral mimicry involving oil-producing flowers and oil-collecting bees. J Chem Ecol. 2007;33:1421-9 pubmed
    ..diversipes hydrolases. These are the chemical clues for bee visitation and oil collecting from both plant species. The results indicate that the deceit/pollination syndrome should not be applied to all Oncidiinae flowers. ..
  78. Bernardes C, Santos Filho N, Costa T, Gomes M, Torres F, Costa J, et al. Isolation and structural characterization of a new fibrin(ogen)olytic metalloproteinase from Bothrops moojeni snake venom. Toxicon. 2008;51:574-84 pubmed publisher
    ..Since the BmooMPalpha-I enzyme was found to cause defibrinogenation when administered i.p. on mice, it is expected that it may be of medical interest as a therapeutic agent in the treatment and prevention of arterial thrombosis...
  79. Calcagnotto M, Ruiz L, Blanco M, Santos Junior J, Valente M, Patti C, et al. Effect of neuronal precursor cells derived from medial ganglionic eminence in an acute epileptic seizure model. Epilepsia. 2010;51 Suppl 3:71-5 pubmed publisher
  80. Kipper M, Andretta I, Lehnen C, Lovatto P, Monteiro S. Meta-analysis of the performance variation in broilers experimentally challenged by Eimeria spp. Vet Parasitol. 2013;196:77-84 pubmed publisher
    ..In general the age effect is superior to the challenge effect, showing that age at the challenge is important to determine the impact of Eimeria infection. ..
  81. Chen Q, Chen O, Martins I, Hou H, Zhao X, Blumberg J, et al. Collagen peptides ameliorate intestinal epithelial barrier dysfunction in immunostimulatory Caco-2 cell monolayers via enhancing tight junctions. Food Funct. 2017;8:1144-1151 pubmed publisher
    ..Thus, collagen peptides may attenuate TNF-? induced barrier dysfunction of Caco-2 cells by inhibiting the NF?B and ERK1/2-mediated MLCK pathway with associated decreases in ZO-1 and occludin protein expression. ..
  82. Pilla C, Cardozo R, Dornelles P, Dutra Filho C, Wyse A, Wajner M, et al. Kinetic studies on the inhibition of creatine kinase activity by branched-chain alpha-amino acids in the brain cortex of rats. Int J Dev Neurosci. 2003;21:145-51 pubmed
    ..In this case, it is possible that creatine supplementation to the diet might benefit MSUD patients. ..
  83. Demarco F, Fay R, Pinzon L, Powers J. Fracture resistance of re-attached coronal fragments--influence of different adhesive materials and bevel preparation. Dent Traumatol. 2004;20:157-63 pubmed
    ..The lowest failure load was obtained with SB in the non-beveled group. No technique studied was able to attain the fracture resistance of the control group and both materials and tooth preparation influenced the fracture resistance. ..
  84. Carvalho J, Leal A, Sousa L, Herani Filho B. Hypertonic glucose solution 10%-25% on the mesenterium and peritoneum of the rat: macroscopic and microscopic study. Acta Cir Bras. 2005;20:455-60 pubmed
    ..05). Hypertonic glucose solution and NaCl 0.9% on the mesenterium and parietal peritoneum do not produce tissue necrosis in a rat and the inflammation process has the same intensity. ..
  85. Zambuzzi W, Oliveira R, Pereira F, Cestari T, Taga R, Granjeiro J. Rat subcutaneous tissue response to macrogranular porous anorganic bovine bone graft. Braz Dent J. 2006;17:274-8 pubmed
    ..In conclusion, the test material induced a foreign body-type granuloma with subsequent fibrosis around the graft particles implanted in rat subcutaneous and did not elicit any immune response, thus being considered biocompatible...
  86. Poersch A, dos Santos F, Maciel M, de Câmara J, de Castro Dantas T, de Syllos Cólus I. Protective effect of DCTN (trans-dehydrocrotonin) against induction of micronuclei and apoptosis by different mutagenic agents in vitro. Mutat Res. 2007;629:14-23 pubmed
    ..These results together with findings reported for DCTN in vivo, support the indication of this active principle at these concentrations for therapeutic use. ..
  87. Santiago M, Vasconcelos R, Fattori K, Munari D, Michelin A, Lima V. An investigation of Leishmania spp. in Didelphis spp. from urban and peri-urban areas in Bauru (São Paulo, Brazil). Vet Parasitol. 2007;150:283-90 pubmed
    ..Evidence of epidemiological risk factors such as a circulating parasite and freely moving vectors suggests that Didelphis spp. may participate in the transmission cycle of Leishmania spp. in Bauru...
  88. Tucunduva de Faria M, Athanazio D, Gonçalves Ramos E, Silva E, Reis M, Ko A. Morphological alterations in the kidney of rats with natural and experimental Leptospira infection. J Comp Pathol. 2007;137:231-238 pubmed publisher
    ..The role of interstitial nephritis in the pathogenesis of leptospirosis is reviewed and it is suggested that rats may provide a potential tool for the study of colonization mechanisms and host resistance in acute leptospiral disease. ..
  89. Abreu N, Tardin J, Boim M, Campos R, Bergamaschi C, Schor N. Hemodynamic parameters during normal and hypertensive pregnancy in rats: evaluation of renal salt and water transporters. Hypertens Pregnancy. 2008;27:49-63 pubmed publisher
    ..Our results suggest that tubule transporter variants may mediate the hemodynamic adaptations seen during pregnancy, although we cannot rule out the hypothesis that other factors are also mediating hemodynamic changes. ..
  90. Saska S, Hochuli Vieira E, Minarelli Gaspar A, Gabrielli M, Capela M, Gabrielli M. Fixation of autogenous bone grafts with ethyl-cyanoacrylate glue or titanium screws in the calvaria of rabbits. Int J Oral Maxillofac Surg. 2009;38:180-6 pubmed publisher
    ..The adhesive was biocompatible, presented similar stability to the screw and maintained the bone area, although there was a delay in graft incorporation...
  91. Bigarella C, Borges L, Costa F, Saad S. ARHGAP21 modulates FAK activity and impairs glioblastoma cell migration. Biochim Biophys Acta. 2009;1793:806-16 pubmed publisher
    ..These results suggest not only that ARHGAP21 might act as a tumor suppressor gene, but also indicate that ARHGAP21 might be a master regulator of migration having a crucial role in controlling the progression of different tumor types. ..
  92. Cardoso Vilela F, Soncini R, Giusti Paiva A. Anxiolytic-like effect of Sonchus oleraceus L. in mice. J Ethnopharmacol. 2009;124:325-7 pubmed publisher
    ..has been used as a general tonic in Brazilian folk medicine. Nevertheless, available scientific information regarding this species is scarce; there are no reports related to its possible effect on the central nervous system...