Experts and Doctors on amino acid sequence in Japan


Locale: Japan
Topic: amino acid sequence

Top Publications

  1. Satokata I, Tanaka K, Miura N, Miyamoto I, Satoh Y, Kondo S, et al. Characterization of a splicing mutation in group A xeroderma pigmentosum. Proc Natl Acad Sci U S A. 1990;87:9908-12 pubmed
    ..The polymorphic AlwNI restriction fragments are concluded to be useful for diagnosis of group A XP in Japanese subjects, including prenatal cases and carriers. ..
  2. Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T. A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. Mol Cell Biol. 1991;11:6041-9 pubmed
    ..Although the exact function of this protein has not been determined, these structural features suggest that ATBF1 plays a transcriptional regulatory role. ..
  3. Higuti T, Osaka F, Yoshihara Y, Tsurumi C, Kawamura Y, Tani I, et al. cDNA cloning and sequencing for the import precursor of coupling factor 6 in H(+)-ATP synthase from rat liver mitochondria. Biochem Biophys Res Commun. 1990;171:1079-86 pubmed
    ..The presequence of 32 amino acids could be the import signal peptide which serves to direct the protein into the mitochondrial matrix. ..
  4. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-5 pubmed
    ..Expression of the endothelin gene is regulated by several vasoactive agents, indicating the existence of a novel cardiovascular control system. ..
  5. Huang L, Yoneda M, Kimata K. A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor. J Biol Chem. 1993;268:26725-30 pubmed
    ..NH2-terminal sequences of the fragments suggested the participation of the COOH-terminal half of ITI with an amphipathic alpha helix structure in the HA binding. ..
  6. Shirasawa T, Sakamoto K, Tkahashi H. Molecular cloning and evolutional analysis of a mammalian homologue of the Distal-less 3 (Dlx-3) homeobox gene. FEBS Lett. 1994;351:380-4 pubmed
  7. Niimi M, Nakai Y, Aida Y. Identification of bovine invariant chain (Ii) gene by nucleotide sequencing. Biochem Biophys Res Commun. 1996;222:7-12 pubmed
    ..Thus, it seems likely that this cDNA clone encodes a functional product which might perform an important function in MHC class II antigen presentation, as previously established in studies in mouse and man. ..
  8. Iwasaki T, Saito Y, Harada E, Kasai M, Shoji K, Miyao M, et al. Cloning of cDNA encoding the rice 22 kDa protein of Photosystem II (PSII-S) and analysis of light-induced expression of the gene. Gene. 1997;185:223-9 pubmed
    ..In dark-adapted green plants, prolonged exposure to blue light induced re-accumulation of transcripts encoding PSII-S, whereas red light had little effect. ..
  9. Hashimoto Y, Khan A. Comparison of ViaB regions of Vi-positive organisms. FEMS Microbiol Lett. 1997;157:55-7 pubmed
    ..freundii groups. The vipR coding sequences of the Salmonella group were identical. Southern blot hybridization results using the full-length ViaB region as a probe support these findings...

More Information

Publications485 found, 100 shown here

  1. Kamikouchi A, Takeuchi H, Sawata M, Ohashi K, Natori S, Kubo T. Preferential expression of the gene for a putative inositol 1,4,5-trisphosphate receptor homologue in the mushroom bodies of the brain of the worker honeybee Apis mellifera L. Biochem Biophys Res Commun. 1998;242:181-6 pubmed publisher
    ..These results suggest that the A1 gene product plays a crucial role in neural transmission in the mushroom bodies of the worker bee brain...
  2. Matsui E, Kawasaki S, Ishida H, Ishikawa K, Kosugi Y, Kikuchi H, et al. Thermostable flap endonuclease from the archaeon, Pyrococcus horikoshii, cleaves the replication fork-like structure endo/exonucleolytically. J Biol Chem. 1999;274:18297-309 pubmed
    ..Because the RF appears to be the intermediate structure, due to the arrest of the replication fork, the double strand breaks after the arrests of the replication forks are probably caused by phFEN...
  3. Kurata A, Ohi K, Sato K, Tashiro M. Purification, characterization, and relation to bikunin of rat urinary trypsin inhibitors. J Protein Chem. 2000;19:693-8 pubmed
    ..1992), Biochim. Biophys. Acta 1130, 63-67] except that the protein sequence seemed to lack C-terminal serine, and UTI-2 corresponded to UTI-1 lacking N-terminal 21 amino acid residues. ..
  4. Hemmi H, Ishibashi J, Hara S, Yamakawa M. Solution structure of moricin, an antibacterial peptide, isolated from the silkworm Bombyx mori. FEBS Lett. 2002;518:33-8 pubmed
    ..The results suggest that the amphipathic N-terminal segment of the alpha-helix is mainly responsible for the increase in permeability of the membrane to kill the bacteria...
  5. Itoh Y, Kawase T, Nikaidou N, Fukada H, Mitsutomi M, Watanabe T, et al. Functional analysis of the chitin-binding domain of a family 19 chitinase from Streptomyces griseus HUT6037: substrate-binding affinity and cis-dominant increase of antifungal function. Biosci Biotechnol Biochem. 2002;66:1084-92 pubmed
    ..Thus, this domain appears to contribute more importantly to antifungal properties than to catalytic activities. ChBD(ChiC) itself did not have antifungal activity or a synergistic effect on the antifungal activity of CatD(ChiC) in trans...
  6. Inose K, Fujikawa M, Yamazaki T, Kojima K, Sode K. Cloning and expression of the gene encoding catalytic subunit of thermostable glucose dehydrogenase from Burkholderia cepacia in Escherichia coli. Biochim Biophys Acta. 2003;1645:133-8 pubmed
    ..The deduced primary structure of gamma subunit showed about 30% identity to the small subunits of the SDH from G. oxydans and 2KGDHs from E. herbicola and P. citrea. ..
  7. Nomura K, Osaki H, Iwanami T, Matsumoto N, Ohtsu Y. Cloning and characterization of a totivirus double-stranded RNA from the plant pathogenic fungus, Helicobasidium mompa Tanaka. Virus Genes. 2003;26:219-26 pubmed
    ..Phylogenetic analysis based on RDRP showed that HmTV1-17 is closely related to Sphaeropsis sapinea SsRV1, a member of the genus Totivirus from filamentous fungus S. sapinea...
  8. Mishima M, Maesaki R, Kasa M, Watanabe T, Fukata M, Kaibuchi K, et al. Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition. Proc Natl Acad Sci U S A. 2007;104:10346-51 pubmed
    ..Thus, our structures provide the structural basis for the specific dynein loading on the microtubule plus end. ..
  9. Takei Y, Yamamoto H, Masuda M, Sato T, Taketani Y, Takeda E. Stanniocalcin 2 is positively and negatively controlled by 1,25(OH)(2)D(3) and PTH in renal proximal tubular cells. J Mol Endocrinol. 2009;42:261-8 pubmed publisher
    ..These results suggest that STC2 is positively and negatively controlled by 1,25(OH)(2)D(3) and PTH in renal proximal tubular cells. ..
  10. Ono R, Kuroki Y, Naruse M, Ishii M, Iwasaki S, Toyoda A, et al. Identification of tammar wallaby SIRH12, derived from a marsupial-specific retrotransposition event. DNA Res. 2011;18:211-9 pubmed publisher
    ..This suggests that SIRH12 retrotransposition occurred only in the marsupial lineage but acquired and retained some as yet unidentified novel function, at least in the lineage of the tammar wallaby. ..
  11. Arai S, Yonezawa Y, Okazaki N, Matsumoto F, Tamada T, Tokunaga H, et al. A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase. Protein Sci. 2012;21:498-510 pubmed publisher
    ..The change in the assembly form by a minimum mutation may be an effective way for NDK to acquire molecular characteristics suited to various circumstances...
  12. Koyama Y, Hidaka M, Nishimoto M, Kitaoka M. Directed evolution to enhance thermostability of galacto-N-biose/lacto-N-biose I phosphorylase. Protein Eng Des Sel. 2013;26:755-61 pubmed publisher
    ..The C236Y and D576V mutations together contributed to the thermostability. The C236Y/D576V mutant exhibited 20°C higher thermostability than the wild type. ..
  13. Ohshige T, Takechi S, Nakayama T. Presence of particular transcription regulatory elements in the 5'-intergenic region shared by the chicken H2A-III and H2B-V pair. Gene. 1993;131:193-9 pubmed
    ..These findings, together with those reported previously on the H2A-V/H2B-II pair, suggest distinct manners of transcription regulation of different members of the chicken histone gene families, H2A and H2B. ..
  14. Imaizumi K, Tsuda M, Imai Y, Wanaka A, Takagi T, Tohyama M. Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death. J Biol Chem. 1997;272:18842-8 pubmed
    ..Overexpression of the full-length DP5 in cultured sympathetic neurons was in itself sufficient to induce apoptosis. These results suggest that DP5 plays a role in programmed neuronal death. ..
  15. Onaka H, Nakagawa T, Horinouchi S. Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis. Mol Microbiol. 1998;28:743-53 pubmed
    ..It is thus concluded that both cprA and cprB play regulatory roles in both secondary metabolism and morphogenesis in S. coelicolor A3(2), just as the arpA/A-factor system in Streptomyces griseus. ..
  16. Nakagawa T, Hirano Y, Inomata A, Yokota S, Miyachi K, Kaneda M, et al. Participation of a fusogenic protein, glyceraldehyde-3-phosphate dehydrogenase, in nuclear membrane assembly. J Biol Chem. 2003;278:20395-404 pubmed
    ..We propose that GAPDH plays a crucial role in the membrane fusion step in nuclear assembly in a Xenopus egg extract cell-free system. ..
  17. Ashida H, Maeda Y, Kinoshita T. DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3. J Biol Chem. 2006;281:896-904 pubmed
    ..Free DPM1 was strongly associated with the C terminus of Hsc70-interacting protein (CHIP), a chaperone-dependent E3 ubiquitin ligase, suggesting that DPM1 is ubiquitinated, at least in part, by CHIP. ..
  18. Senoo H, Wang H, Araki T, Williams J, Fukuzawa M. An orthologue of the Myelin-gene Regulatory Transcription Factor regulates Dictyostelium prestalk differentiation. Int J Dev Biol. 2012;56:325-32 pubmed publisher
    ..These results provide a first insight into the intracellular signaling pathway that directs pstA differentiation and identify a non-metazoan orthologue of a family of molecularly uncharacterised transcription factors...
  19. Oda Y, Nakanishi I, Deguchi T. A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells. Brain Res Mol Brain Res. 1992;16:287-94 pubmed
    ..It might be that the larger form of ChAT molecule is an enzyme precursor for processing or that the N-terminal extrapeptide is needed for subcellular localization of the enzyme. ..
  20. Higashijima S, Kojima T, Michiue T, Ishimaru S, Emori Y, Saigo K. Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development. Genes Dev. 1992;6:50-60 pubmed
    ..Taken together, our results suggest that Bar homeo domain proteins may play key roles in the fate-determination processes of pigment cells and cone cells. ..
  21. Igarashi M, Nagata A, Toh H, Urade Y, Hayaishi O. Structural organization of the gene for prostaglandin D synthase in the rat brain. Proc Natl Acad Sci U S A. 1992;89:5376-80 pubmed
  22. Odai H, Sasaki K, Iwamatsu A, Hanazono Y, Tanaka T, Mitani K, et al. The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells. J Biol Chem. 1995;270:10800-5 pubmed
    ..These findings strongly suggest that c-Cbl is implicated in the signal transduction of GM-CSF or Epo in hematopoietic cells and that c-Cbl is involved in another signaling pathway different from the Ras signaling pathway. ..
  23. Sohda M, Misumi Y, Fujiwara T, Nishioka M, Ikehara Y. Molecular cloning and sequence analysis of a human 372-kDA protein localized in the Golgi complex. Biochem Biophys Res Commun. 1994;205:1399-408 pubmed
    ..These results indicate that the 372-kDa antigen is cytoplasmically disposed and anchored to the Golgi membrane by the COOH-terminal hydrophobic domain. ..
  24. Sekine Y, Okada Y, Noda Y, Kondo S, Aizawa H, Takemura R, et al. A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally. J Cell Biol. 1994;127:187-201 pubmed
    ..Hence we conclude that KIF4 is a novel microtubule-associated anterograde motor protein for membranous organelles, the expression of which is regulated developmentally. ..
  25. Iwahana H, Oka J, Mizusawa N, Kudo E, Ii S, Yoshimoto K, et al. Molecular cloning of human amidophosphoribosyltransferase. Biochem Biophys Res Commun. 1993;190:192-200 pubmed
    ..Comparison with rat and chicken ATases showed that two cysteine residues for an iron-sulfur cluster were conserved. Four consensus phosphorylation sites for cAMP-dependent protein kinase were found. ..
  26. Kanatani K, Tahara T, Oshimura M, Sano K, Umezawa C. Cloning and nucleotide sequence of the gene for acidocin 8912, a bacteriocin from Lactobacillus acidophilus TK8912. Lett Appl Microbiol. 1995;21:384-6 pubmed
    ..The precursor sequence of the acdT gene shows a conservation of the general structural characteristics of the bacteriocin precursors from some lactic acid bacteria. ..
  27. Shimomura A, Ogawa Y, Kitani T, Fujisawa H, Hagiwara M. Calmodulin-dependent protein kinase II potentiates transcriptional activation through activating transcription factor 1 but not cAMP response element-binding protein. J Biol Chem. 1996;271:17957-60 pubmed
    ..As expected from these in vitro studies, transient transfection studies revealed that ATF1 is activated by CaMK II. Our findings suggest that CaMK II mediates transactivation of cAMP responsive genes via ATF1. ..
  28. Iwatsuki K, Shinozaki M, Hattori N, Hirasawa K, Itagaki S, Shiota K, et al. Molecular cloning and characterization of a new member of the rat placental prolactin (PRL) family, PRL-like protein D (PLP-D). Endocrinology. 1996;137:3849-55 pubmed
    ..Differentiated Rcho-1 cells also expressed PLP-D mRNA, whereas undifferentiated Rcho-1 cells did not. ..
  29. Misawa H, Matsuura J, Oda Y, Takahashi R, Deguchi T. Human choline acetyltransferase mRNAs with different 5'-region produce a 69-kDa major translation product. Brain Res Mol Brain Res. 1997;44:323-33 pubmed
    ..Sequencing of monkey ChAT gene showed that the initiation ATG in rodent ChAT was also replaced by ACA in the monkey. ..
  30. Komori K, Kuroe K, Yanagisawa K, Tanaka Y. Cloning and characterization of the gene encoding a mitochondrially localized DNA topoisomerase II in Dictyostelium discoideum. Western blot analysis. Biochim Biophys Acta. 1997;1352:63-72 pubmed
    ..The protein and the mRNA are present in growth phase and during development, although levels of both declined as development proceeded. ..
  31. Sugai M, Fujiwara T, Ohta K, Komatsuzawa H, Ohara M, Suginaka H. epr, which encodes glycylglycine endopeptidase resistance, is homologous to femAB and affects serine content of peptidoglycan cross bridges in Staphylococcus capitis and Staphylococcus aureus. J Bacteriol. 1997;179:4311-8 pubmed
    ..These results suggest that epr and femAB belong to the protein family involved in adding amino acids to the pentapeptide peptidoglycan precursor and that epr is involved in the addition of serine to the pentapeptide. ..
  32. Yamaoka K, Masuda K, Ogawa H, Takagi K, Umemoto N, Yasuoka S. Cloning and characterization of the cDNA for human airway trypsin-like protease. J Biol Chem. 1998;273:11895-901 pubmed
    ..The noncatalytic region had little similarity to other known proteins. In Northern blot analysis a transcript of 1.9 kilobases was detectable most prominently in the trachea among 17 human tissues examined. ..
  33. Ohno K, Terado M, Iwata H, Inokuma H, Onishi T. Expression of recombinant feline serum amyloid A (SAA) protein. J Vet Med Sci. 1999;61:915-20 pubmed
    ..Furthermore, antibodies against human SAA did not react with feline SAA. These results indicate that antigenicity of feline SAA is totally different from human SAA. ..
  34. Fujii R, Fukusumi S, Hosoya M, Kawamata Y, Habata Y, Hinuma S, et al. Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor. Regul Pept. 1999;83:1-10 pubmed
    ..The wide distribution of PrRP and its receptor suggests that they have various functions not only in the pituitary gland but also in the other tissues. ..
  35. Ota Y, Tamegai H, Kudo F, Kuriki H, Koike Takeshita A, Eguchi T, et al. Butirosin-biosynthetic gene cluster from Bacillus circulans. J Antibiot (Tokyo). 2000;53:1158-67 pubmed
    ..Therefore, the gene cluster found so far was determined to be a part of the butirosin biosynthetic gene cluster. Functions of some ORFs are also discussed in terms of butirosin biosynthesis on the basis of database search. ..
  36. Suzuki O, Mochida K, Yamamoto Y, Noguchi Y, Takano K, Matsuda J, et al. Comparison of glycoprotein hormone alpha-subunits of laboratory animals. Mol Reprod Dev. 2002;62:335-42 pubmed
    ..Phylogenetic trees constructed from amino acid sequences suggest a closer relationship between the guinea pig and artiodactyls than to rodents, confirming the taxonomic peculiarity of the guinea pig. ..
  37. Matsui K, Yuyama N, Akaiwa M, Yoshida N, Maeda M, Sugita Y, et al. Identification of an alternative splicing variant of cathepsin C/dipeptidyl-peptidase I. Gene. 2002;293:1-7 pubmed
    ..These results indicate that the variant may play a role in regulating the biological activities of cathepsin C, involved in the pathogenesis of bronchial asthma. ..
  38. Nagasaki A, Itoh G, Yumura S, Uyeda T. Novel myosin heavy chain kinase involved in disassembly of myosin II filaments and efficient cleavage in mitotic dictyostelium cells. Mol Biol Cell. 2002;13:4333-42 pubmed
    ..Taken together, these findings suggest MHCK C drives the disassembly of myosin II filaments for efficient cytokinesis and recycling of myosin II that occurs during cytokinesis. ..
  39. Tsujimoto Y, Numaga T, Ohshima K, Yano M, Ohsawa R, Goto D, et al. Arabidopsis TOBAMOVIRUS MULTIPLICATION (TOM) 2 locus encodes a transmembrane protein that interacts with TOM1. EMBO J. 2003;22:335-43 pubmed
    ..thaliana presumed to be an essential constituent of tobamovirus replication complex. The data presented here suggest that TOM2A is also an integral part of the tobamovirus replication complex...
  40. Miyadera H, Hiraishi A, Miyoshi H, Sakamoto K, Mineki R, Murayama K, et al. Complex II from phototrophic purple bacterium Rhodoferax fermentans displays rhodoquinol-fumarate reductase activity. Eur J Biochem. 2003;270:1863-74 pubmed
    ..The results strongly indicate that R. fermentans complex II and mitochondrial QFR might have evolved independently, although they both utilize RQ for fumarate reduction. ..
  41. Muramoto T, Suzuki K, Shimizu H, Kohara Y, Kohriki E, Obara S, et al. Construction of a gamete-enriched gene pool and RNAi-mediated functional analysis in Dictyostelium discoideum. Mech Dev. 2003;120:965-75 pubmed
    ..RNAi-mediated silencing as well as disruption of gmsA reduced the cellular competency for sexual cell fusion, indicating the involvement of this gene in the sexual development of D. discoideum. ..
  42. Oda M, Kobayashi N, Fujita M, Miyazaki Y, Sadaie Y, Kurusu Y, et al. Analysis of HutP-dependent transcription antitermination in the Bacillus subtilis hut operon: identification of HutP binding sites on hut antiterminator RNA and the involvement of the N-terminus of HutP in binding of HutP to the antiterminator RNA. Mol Microbiol. 2004;51:1155-68 pubmed
    ..A 25-mer peptide consisting of amino acid residues 2-26 of HutP bound to the antiterminator RNA. These results indicated that the N-terminus of HutP is involved in binding of HutP to the antiterminator RNA. ..
  43. Ikeda Y, Miyazawa T, Nishimura Y, Nakamura K, Tohya Y, Mikami T. High genetic stability of TM1 and TM2 strains of subtype B feline immunodeficiency virus in long-term infection. J Vet Med Sci. 2004;66:287-9 pubmed
    ..7 y.p.i., 3 nucleotide insertions (one amino acid insertion) in region V5, and 1 synonymous nucleotide substitution and 2 non-synonymous nucleotide substitutions in region V5, were observed. ..
  44. Suzuki R, Sakamoto S, Tsutsumi T, Rikimaru A, Tanaka K, Shimoike T, et al. Molecular determinants for subcellular localization of hepatitis C virus core protein. J Virol. 2005;79:1271-81 pubmed
    ..Differences in the cellular trafficking of HCV core protein, achieved and maintained by multiple targeting functions as mentioned above, may in part regulate the diverse range of biological roles of the core protein. ..
  45. Tsuzuki M, Wu W, Nishikawa H, Hayami R, Oyake D, Yabuki Y, et al. A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats. Cancer Lett. 2006;233:108-16 pubmed
    ..DeltaRIN does not interact with BRCA1, whereas it interacts with and colocalizes with CstF-50 to cytoplasmic dots. Hence, a deletion variant of BARD1 occurs in cells and may play a distinct role with CstF-50. ..
  46. Shitara M, Tsuboi Y, Sekizuka T, Tazumi A, Moorei J, Millar B, et al. Genetic heterogeneity of the dnaK gene locus including transcription terminator region (TTR) in Campylobacter lari. Br J Biomed Sci. 2008;65:95-101 pubmed
    ..lari forms two major distinct clusters consisting of UPTC and UN C. lari isolates, respectively, with UN C. lari being more closely related to other thermophilic campylobacters than to UPTC...
  47. Karim N, Jones J, Okada H, Kikuchi T. Analysis of expressed sequence tags and identification of genes encoding cell-wall-degrading enzymes from the fungivorous nematode Aphelenchus avenae. BMC Genomics. 2009;10:525 pubmed publisher
    ..Expressed sequence tag (EST) analysis may therefore be useful in providing an initial insight into the poorly understood genetic background of A. avenae...
  48. Takagaki K, Satoh K, Honda S, Shibuya A. Molecular characterization of the dimer formation of Fc?/? receptor (CD351). Mol Immunol. 2013;56:23-7 pubmed publisher
    ..Instead, our data suggest that Fc?/?R forms heterodimers with an as-yet-unknown molecule with a molecular weight of 60-70 kDa. ..
  49. Kanazawa T, Era A, Minamino N, Shikano Y, Fujimoto M, Uemura T, et al. SNARE Molecules in Marchantia polymorpha: Unique and Conserved Features of the Membrane Fusion Machinery. Plant Cell Physiol. 2016;57:307-24 pubmed publisher
    ..These results suggest that M. polymorpha has acquired unique membrane trafficking pathways associated with newly acquired machinery components during evolution. ..
  50. Niidome T, Kim M, Friedrich T, Mori Y. Molecular cloning and characterization of a novel calcium channel from rabbit brain. FEBS Lett. 1992;308:7-13 pubmed
  51. Tomida Y, Terasawa M, Kobayashi R, Hidaka H. Calcyclin and calvasculin exist in human platelets. Biochem Biophys Res Commun. 1992;189:1310-6 pubmed
  52. Kohmura N, Yagi T, Tomooka Y, Oyanagi M, Kominami R, Takeda N, et al. A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption. Mol Cell Biol. 1994;14:6915-25 pubmed
    ..These results suggest that Srm constitutes a new family of nonreceptor tyrosine kinases that may be redundant in function. ..
  53. Mikuni O, Ito K, Moffat J, Matsumura K, McCaughan K, Nobukuni T, et al. Identification of the prfC gene, which encodes peptide-chain-release factor 3 of Escherichia coli. Proc Natl Acad Sci U S A. 1994;91:5798-802 pubmed
    ..A completely null prfC mutation made by reverse genetics affected the cell growth under the limited set of physiological and strain conditions. ..
  54. Sekito T, Okamoto K, Kitano H, Yoshida K. The complete mitochondrial DNA sequence of Hansenula wingei reveals new characteristics of yeast mitochondria. Curr Genet. 1995;28:39-53 pubmed
    ..wingei mitochondrial genome in terms of characteristics which are typical for both yeast and for filamentous fungi. This is the first complete mt DNA sequence report in yeast. ..
  55. Miyazato M, Nakazato M, Yamaguchi H, Date Y, Kojima M, Kangawa K, et al. Cloning and characterization of a cDNA encoding a precursor for human uroguanylin. Biochem Biophys Res Commun. 1996;219:644-8 pubmed
    ..Uroguanylin, as well as guanylin, may be a potent physiological regulator of intestinal fluid and electrolyte transport. ..
  56. Shinga J, Kashiwagi K, Tashiro K, Igarashi K, Shiokawa K. Maternal and zygotic expression of mRNA for S-adenosylmethionine decarboxylase and its relevance to the unique polyamine composition in Xenopus oocytes and embryos. Biochim Biophys Acta. 1996;1308:31-40 pubmed
    ..coli-type polyamine composition is a necessary factor for the normal embryogenic development in Xenopus and its maintenance, especially that in pre-neurula stages, can be explained by the low level of both SAMDC mRNA and SAMDC. ..
  57. Aita N, Ishii K, Akamatsu Y, Ogasawara Y, Tanabe S. Cloning and expression of human liver rhodanese cDNA. Biochem Biophys Res Commun. 1997;231:56-60 pubmed
    ..6% identical to bovine, 90.2% identical to rat, 91.2% identical to mouse and Chinese hamster, and 71.4% similar to avian counterparts, respectively, and that rhodanese was highly conserved across evolution. ..
  58. Tanaka K, Handel K, Loewen P, Takahashi H. Identification and analysis of the rpoS-dependent promoter of katE, encoding catalase HPII in Escherichia coli. Biochim Biophys Acta. 1997;1352:161-6 pubmed
    ..A - 10 sequence similar to that found in other sigma70- and sigma38-dependent E. coli promoters was identified 8 or 7 bp upstream of the start site but a sigma70-dependent -35 sequence was not evident. ..
  59. Izu H, Kawai T, Yamada Y, Aoshima H, Adachi O, Yamada M. Characterization of the gntT gene encoding a high-affinity gluconate permease in Escherichia coli. Gene. 1997;199:203-10 pubmed
    ..Gluconate-specific uptake activity was observed with cells harboring the gntT plasmid clone, which was enhanced by the presence of gntK encoding gluconate kinase. ..
  60. Suzuki T, Kawasaki Y, Furukohri T, Ellington W. Evolution of phosphagen kinase. VI. Isolation, characterization and cDNA-derived amino acid sequence of lombricine kinase from the earthworm Eisenia foetida, and identification of a possible candidate for the guanidine substrate recognition site. Biochim Biophys Acta. 1997;1343:152-9 pubmed
    ..A phylogenetic analysis using amino acid sequences of all four phosphagen kinases indicates that CK, GK and LK probably evolved from a common immediate ancestor protein. ..
  61. Sagane K, Ohya Y, Hasegawa Y, Tanaka I. Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain. Biochem J. 1998;334 ( Pt 1):93-8 pubmed
    ..Northern blot analysis revealed that the mRNAs of MDC2, MDC3 and MDC/ADAM11 are highly expressed in the brain. These findings suggest that these proteins may function as integrin ligands in the brain. ..
  62. Adachi N, Matsumoto M, Hasegawa S, Yamamoto T, Horikoshi M. Analysis of TFIIH subunit through isolation of the gene from Schizosaccharomyces pombe corresponding to that of Saccharomyces cerevisiae SSL1, reveals the presence of conserved structural motifs. Yeast. 1999;15:255-62 pubmed
    ..This nucleotide sequence has been deposited in the GenBank Data Library under Accession Number AF017646. ..
  63. Katada T, Kurosu H, Okada T, Suzuki T, Tsujimoto N, Takasuga S, et al. Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors. Chem Phys Lipids. 1999;98:79-86 pubmed
  64. Lee J, Takahashi T, Yasuhara N, Inazawa J, Kamada S, Tsujimoto Y. Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene. 1999;18:6183-90 pubmed
    ..These results suggest that Bis is a novel modulator of cellular anti-apoptotic activity that functions through its interaction with Bcl-2. ..
  65. Yang Z, Imoto I, Fukuda Y, Pimkhaokham A, Shimada Y, Imamura M, et al. Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res. 2000;60:4735-9 pubmed
    ..Our findings suggest that overexpressed GASC1 may play an important role in the development and/or progression of various types of cancer including ESC. ..
  66. Aono S, Kato T, Matsuki M, Nakajima H, Ohta T, Uchida T, et al. Resonance Raman and ligand binding studies of the oxygen-sensing signal transducer protein HemAT from Bacillus subtilis. J Biol Chem. 2002;277:13528-38 pubmed
    ..Based on these results, the structural and functional properties of HemAT-Bs are discussed. ..
  67. Mitsuda Y, Hifumi E, Tsuruhata K, Fujinami H, Yamamoto N, Uda T. Catalytic antibody light chain capable of cleaving a chemokine receptor CCR-5 peptide with a high reaction rate constant. Biotechnol Bioeng. 2004;86:217-25 pubmed
    ..The heavy chain of ECL2B-2 MAb, which has no catalytic triad because of a lack of His residue, did not degrade the CCR-5 peptide. ..
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