Experts and Doctors on adenylyl cyclases in United States
Locale: United States
Topic: adenylyl cyclases
Wilkins P, Suchovsky D, Berti Mattera L. Immortalized schwann cells express endothelin receptors coupled to adenylyl cyclase and phospholipase C. Neurochem Res. 1997;22:409-18 pubmed
..The actions of ETs on Schwann cells provide a novel example of the influence of vascular factors on nerve function. ..
Hardwick J, Clason T, Tompkins J, Girard B, Baran C, Merriam L, et al
. Recruitment of endosomal signaling mediates the forskolin modulation of guinea pig cardiac neuron excitability. Am J Physiol Cell Physiol. 2017;313:C219-C227 pubmed publisher
Roman T, Cannon M, Vadlamudi S, Buchkovich M, Wolford B, Welch R, et al
. A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus. Diabetes. 2017;66:2521-2530 pubmed publisher
..Together, these data suggest that rs11708067-A risk allele contributes to type 2 diabetes by disrupting an islet enhancer, which results in reduced ADCY5 expression and impaired insulin secretion. ..