Experts and Doctors on saccharomyces cerevisiae in Copenhagen, Capital Region, Denmark


Locale: Copenhagen, Capital Region, Denmark
Topic: saccharomyces cerevisiae

Top Publications

  1. Stennicke H, Mortensen U, Breddam K. Studies on the hydrolytic properties of (serine) carboxypeptidase Y. Biochemistry. 1996;35:7131-41 pubmed
    ..They describe how the catalytically essential histidine is maintained in its active deprotonated state through perturbation of its pKa value in the enzyme-substrate complex. ..
  2. Køhler J, Jørgensen M, Beinoraité G, Thorsen M, Thon G. Concerted action of the ubiquitin-fusion degradation protein 1 (Ufd1) and Sumo-targeted ubiquitin ligases (STUbLs) in the DNA-damage response. PLoS ONE. 2013;8:e80442 pubmed publisher
    ..Broader functional relationships between Ufd1 and STUbLs conceivably affect numerous cellular processes beyond the DDR...
  3. Torbensen R, Møller H, Gresham D, Alizadeh S, Ochmann D, Boles E, et al. Amino acid transporter genes are essential for FLO11-dependent and FLO11-independent biofilm formation and invasive growth in Saccharomyces cerevisiae. PLoS ONE. 2012;7:e41272 pubmed publisher
    ..Increased intracellular amino acid pools in the PTR3(647::CWNKNPLSSIN)-containing strain opens the possibility that Gap1 regulates the FLO genes through alteration of the amino acid pool sizes. ..
  4. Arendrup M, Sulim S, Holm A, Nielsen L, Nielsen S, Knudsen J, et al. Diagnostic issues, clinical characteristics, and outcomes for patients with fungemia. J Clin Microbiol. 2011;49:3300-8 pubmed publisher
    ..5% if current guidelines had been followed. A large proportion of Danish fungemia patients were severely ill and received suboptimal initial antifungal treatment. Optimization of diagnosis and therapy is possible...
  5. Rendtorff N, Zhu M, Fagerheim T, Antal T, Jones M, Teslovich T, et al. A novel missense mutation in ACTG1 causes dominant deafness in a Norwegian DFNA20/26 family, but ACTG1 mutations are not frequent among families with hereditary hearing impairment. Eur J Hum Genet. 2006;14:1097-105 pubmed
    ..Finally, the present results do not indicate that mutations in ACTG1 are a frequent cause of autosomal-dominant postlingual sensorineural hearing impairment in Norway nor Denmark. ..
  6. Jønson L, Rehfeld J, Johnsen A. Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae. Eur J Biochem. 2004;271:4788-97 pubmed
    ..The protease does not require post-translational processing prior to activation and it contains cytosolic activity that processes peptides designated for the secretory pathway prior to translocation into the endoplasmic reticulum. ..
  7. Tarabykina S, Kriajevska M, Scott D, Hill T, Lafitte D, Derrick P, et al. Heterocomplex formation between metastasis-related protein S100A4 (Mts1) and S100A1 as revealed by the yeast two-hybrid system. FEBS Lett. 2000;475:187-91 pubmed
    ..Mutational analysis revealed that replacement of Cys(76) and/or Cys(81) of S100A4 by Ser abolishes the S100A4/S100A1 heterodimerization, but does not affect the S100A4 homodimerization in vivo. ..
  8. Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen C, et al. CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis. Plant J. 2003;33:923-37 pubmed
  9. Hartmann Petersen R, Semple C, Ponting C, Hendil K, Gordon C. UBA domain containing proteins in fission yeast. Int J Biochem Cell Biol. 2003;35:629-36 pubmed
    ..The proteins display remarkable differences in their domain organisation, indicating that these potential ubiquitin binding proteins are involved in various cell activities. ..

More Information


  1. Bak S, Feyereisen R. The involvement of two p450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis. Plant Physiol. 2001;127:108-18 pubmed
  2. Andreasson E, Jenkins T, Brodersen P, Thorgrimsen S, Petersen N, Zhu S, et al. The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO J. 2005;24:2579-89 pubmed
    ..MKS1 may therefore contribute to MPK4-regulated defense activation by coupling the kinase to specific WRKY transcription factors. ..
  3. Pedas P, Ytting C, Fuglsang A, Jahn T, Schjoerring J, Husted S. Manganese efficiency in barley: identification and characterization of the metal ion transporter HvIRT1. Plant Physiol. 2008;148:455-66 pubmed publisher
    ..We conclude that HvIRT1 is an important component controlling Mn(2+) uptake in barley roots and contributes to genotypic differences in Mn(2+) uptake kinetics...
  4. WENDLAND J, Schaub Y, Walther A. N-acetylglucosamine utilization by Saccharomyces cerevisiae based on expression of Candida albicans NAG genes. Appl Environ Microbiol. 2009;75:5840-5 pubmed publisher
    ..Our results present the first step toward tapping a novel, renewable carbon source for biofuel production. ..
  5. Hansen J, Johannesen P. Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet. 2000;263:535-42 pubmed
    ..While some repression of MET genes could be accomplished by homocysteine in a strain that cannot form SAM from methionine, a low intracellular level of SAM seems to be necessary for full cysteine-mediated repression to take place. ..
  6. Mikkelsen M, Buron L, Salomonsen B, Olsen C, Hansen B, Mortensen U, et al. Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform. Metab Eng. 2012;14:104-11 pubmed publisher
    ..Production of indolylglucosinolate serves as a proof-of-concept for our expression platform, and provides a basis for large-scale microbial production of specific glucosinolates for the benefit of human health. ..
  7. Tarabykina S, Møller A, Durussel I, Cox J, Berchtold M. Two forms of the apoptosis-linked protein ALG-2 with different Ca(2+) affinities and target recognition. J Biol Chem. 2000;275:10514-8 pubmed
    ..Pellegrini, L., Guiet, C., and D'Adamio, L. (1999) J. Biol. Chem. 274, 1533-1540). We propose that the minor sequence difference between ALG-2,5 and ALG-2,1 affects the Ca(2+) binding properties and function of the proteins. ..
  8. Møldrup M, Salomonsen B, Halkier B. Engineering of glucosinolate biosynthesis: candidate gene identification and validation. Methods Enzymol. 2012;515:291-313 pubmed publisher
    ..We anticipate that the methodology presented here will be beneficial to elucidate and engineer other plant biosynthetic pathways. ..
  9. Scharff Poulsen P, Pedersen P. Saccharomyces cerevisiae-based platform for rapid production and evaluation of eukaryotic nutrient transporters and transceptors for biochemical studies and crystallography. PLoS ONE. 2013;8:e76851 pubmed publisher
    ..In conclusion, we developed a new effective S. cerevisiae expression system that may be used for production of high-quality eukaryotic membrane proteins for functional and structural analysis. ..
  10. Rasmussen S. A 37.5 kb region of yeast chromosome X includes the SME1, MEF2, GSH1 and CSD3 genes, a TCP-1-related gene, an open reading frame similar to the DAL80 gene, and a tRNA(Arg). Yeast. 1995;11:873-83 pubmed
    ..Finally, the sequence contained a tRNA(Arg3) (AGC) gene. ..
  11. Bocquet N, Bizard A, Abdulrahman W, Larsen N, Faty M, Cavadini S, et al. Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase III? and RMI1. Nat Struct Mol Biol. 2014;21:261-8 pubmed publisher
    ..Our results provide a mechanistic rationale for how RMI1 stabilizes TopIII?-gate opening to enable dissolution and illustrate how binding partners modulate topoisomerase function. ..
  12. Galluzzi L, Baehrecke E, Ballabio A, Boya P, Bravo San Pedro J, Cecconi F, et al. Molecular definitions of autophagy and related processes. EMBO J. 2017;36:1811-1836 pubmed publisher
    ..The ultimate objective of this collaborative exchange is to formulate recommendations that facilitate the dissemination of knowledge within and outside the field of autophagy research. ..