Experts and Doctors on animals in Copenhagen, Capital Region, Denmark


Locale: Copenhagen, Capital Region, Denmark
Topic: animals

Top Publications

  1. Andersen K, Poulsen F. Three-dimensional structure in solution of acyl-coenzyme A binding protein from bovine liver. J Mol Biol. 1992;226:1131-41 pubmed
    ..The programs DIANA and X-PLOR have been used in the structure calculations and evaluations. ..
  2. Mikkelsen J, Møller M. Neuropeptide Y in the mammalian pineal gland. Microsc Res Tech. 1999;46:239-56 pubmed
    ..Possible roles of NPY in pineal biochemistry and physiology are discussed. ..
  3. Andreasen S, Christensen J, Marker O, Thomsen A. Role of CD40 ligand and CD28 in induction and maintenance of antiviral CD8+ effector T cell responses. J Immunol. 2000;164:3689-97 pubmed
    ..Thus, our results demonstrate that the importance of CD40/CD40L interaction for activation of CD8+ T cells varies between viruses and over time. ..
  4. Jensen J. Mycoplasma genitalium infections. Diagnosis, clinical aspects, and pathogenesis. Dan Med Bull. 2006;53:1-27 pubmed
  5. Brandt C, Holm D, Liptrot M, Ostergaard C, Lundgren J, Frimodt Møller N, et al. Impact of bacteremia on the pathogenesis of experimental pneumococcal meningitis. J Infect Dis. 2008;197:235-44 pubmed publisher
    ..The different end points affected by the systemic and local infectious processes should be addressed in future studies. ..
  6. Fahrenkrug J, Hannibal J, Georg B. Diurnal rhythmicity of the canonical clock genes Per1, Per2 and Bmal1 in the rat adrenal gland is unaltered after hypophysectomy. J Neuroendocrinol. 2008;20:323-9 pubmed publisher
  7. Ugelvig L, Drijfhout F, Kronauer D, Boomsma J, Pedersen J, Cremer S. The introduction history of invasive garden ants in Europe: integrating genetic, chemical and behavioural approaches. BMC Biol. 2008;6:11 pubmed publisher
    ..This indicates that existing introduced populations have a very high invasive potential when the ants are inadvertently spread by human transport. ..
  8. Ostenfeld M, Høyer Hansen M, Bastholm L, Fehrenbacher N, Olsen O, Groth Pedersen L, et al. Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Autophagy. 2008;4:487-99 pubmed
    ..Threrefore, the combination of siramesine with inhibitors of autophagosome formation appears as a promising approach for future cancer therapy. ..
  9. Grujic M, Christensen J, Sørensen M, Abrink M, Pejler G, Thomsen A. Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin. J Immunol. 2008;181:1043-51 pubmed
    ..In summary, the present report points to a novel, previously unrecognized role for serglycin proteoglycan in regulating the kinetics of antiviral CD8(+) T cell responses. ..

More Information

Publications536 found, 100 shown here

  1. Fehrenbacher N, Bastholm L, Kirkegaard Sørensen T, Rafn B, Bøttzauw T, Nielsen C, et al. Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res. 2008;68:6623-33 pubmed publisher
    ..These data indicate that aggressive cancers with high cysteine cathepsin levels are especially sensitive to lysosomal cell death pathways and encourage the further development of lysosome-targeting compounds for cancer therapy. ..
  2. Magistrado P, Staalsoe T, Theander T, Hviid L, Jensen A. CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression. Malar J. 2008;7:204 pubmed publisher
    ..The current findings are consistent with the notion that CD36 adhesion is not associated with particular virulent parasite phenotypes, such as those believed to be exhibited by VAR4 expressing parasites. ..
  3. Schmidt L, Miller A, Lester D, Bay Richter C, Schülein C, Frikke Schmidt H, et al. Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice. Psychopharmacology (Berl). 2010;207:547-58 pubmed publisher
    ..These results support the concept that the M(5) receptor modulates effects of addictive drugs. ..
  4. Owczarek S, Kiryushko D, Larsen M, Kastrup J, Gajhede M, Sandi C, et al. Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor. FASEB J. 2010;24:1139-50 pubmed publisher
    ..Owczarek, S., Kiryushko, D., Larsen, M. H., Kastrup, J. S., Gajhede, M., Sandi, C., Berezin, V., Bock, E., Soroka, V. Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor. ..
  5. Køhler L, Soroka V, Korshunova I, Berezin V, Bock E. A peptide derived from a trans-homophilic binding site in neural cell adhesion molecule induces neurite outgrowth and neuronal survival. J Neurosci Res. 2010;88:2165-76 pubmed publisher
  6. Christensen C, Gjetting T, Poulsen T, Cramer F, Roth J, Poulsen H. Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay. Clin Cancer Res. 2010;16:2308-19 pubmed publisher
    ..The current study is the first to test cytosine deaminase-based suicide gene therapy for SCLC and the first to show an antitumor effect from the delivery of suicide gene therapeutics for SCLC in vivo. ..
  7. Choudhary C, Mann M. Decoding signalling networks by mass spectrometry-based proteomics. Nat Rev Mol Cell Biol. 2010;11:427-39 pubmed publisher
    ..Large-scale proteomics-based signalling research will fundamentally change our understanding of signalling networks. ..
  8. Kunding A, Christensen S, Danielsen E, Hansen G. Domains of increased thickness in microvillar membranes of the small intestinal enterocyte. Mol Membr Biol. 2010;27:170-7 pubmed publisher
  9. Thomsen M, Hansen H, Mikkelsen J. ?7 nicotinic receptor agonism mitigates phencyclidine-induced changes in synaptophysin and Arc gene expression in the mouse prefrontal cortex. Neurochem Int. 2010;57:756-61 pubmed publisher
    ..These data lend support to the potential for development of ?7 nAChR agonists for the treatment of cognitive deficits in schizophrenia. ..
  10. Ossum C, Lauritsen A, Karottki D, Hoffmann E. Differential role for ERK2 in anoxia-induced activation of transcription and translation of Hsp70 in NIH 3T3 cells. Cell Physiol Biochem. 2011;27:109-20 pubmed publisher
    ..Inhibition of ERK2 by the MEK inhibitor PD98059 resulted in strong inhibition of Hsp70 protein expression and simultaneous stimulation of hsp70 transcription. ..
  11. Hald B, Jacobsen J, Braunstein T, Inoue R, Ito Y, Sørensen P, et al. BKCa and KV channels limit conducted vasomotor responses in rat mesenteric terminal arterioles. Pflugers Arch. 2012;463:279-95 pubmed publisher
    ..This finding is potentially relevant to understanding the compromised microcirculatory blood flow in systemic vascular diseases such as diabetes mellitus and hypertension. ..
  12. Persson M, Madsen J, Østergaard S, Jensen M, Jørgensen J, Juhl K, et al. Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion. J Nucl Med. 2012;53:138-45 pubmed publisher
  13. Madsen C, Klausen T, Fabian A, Hansen B, Pedersen S, Hoffmann E. On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle. Am J Physiol Cell Physiol. 2012;303:C625-34 pubmed publisher
  14. Winkelmann I, Campos P, Strugnell J, Cherel Y, Smith P, Kubodera T, et al. Mitochondrial genome diversity and population structure of the giant squid Architeuthis: genetics sheds new light on one of the most enigmatic marine species. Proc Biol Sci. 2013;280:20130273 pubmed publisher
    ..Demographic history analyses of the genetic data suggest that there has been a recent population expansion or selective sweep, which may explain the low level of genetic diversity. ..
  15. Veland I, Montjean R, Eley L, Pedersen L, Schwab A, Goodship J, et al. Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration. PLoS ONE. 2013;8:e60193 pubmed publisher
  16. Dalgaard T, Norup L, Juul Madsen H. Detection of Avian Antigen-Specific T Cells Induced by Viral Vaccines. Methods Mol Biol. 2016;1404:77-88 pubmed publisher
    ..This method has been successfully applied to studies of chicken antigen-specific T cells. ..
  17. Rosenbaek L, Rizzo F, MacAulay N, Staub O, Fenton R. Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells. Am J Physiol Renal Physiol. 2017;313:F495-F504 pubmed publisher
    ..In conclusion, this system allows the activity, cellular localization, and abundance of wild-type or mutant NCC to be examined in the same polarized mammalian expression system in a rapid, easy, and low-cost fashion. ..
  18. Glenert U. Acute effects of a possible sialogogue, anethole trithione, in rat parotid glands. Eur J Pharmacol. 1991;208:287-95 pubmed
    ..In conclusion, this study has shown that anethole trithione is not to be considered as a simple cholinergic agonist like pilocarpine, and further elucidation of the mechanism(s) of action of this agent would be useful. ..
  19. Jensen H, Schønheyder H, Jørgensen J. Intestinal and pulmonary mycotic lymphadenitis in cattle. J Comp Pathol. 1990;102:345-55 pubmed
    ..avium) was diagnosed in one case. Thus, zygomycetes are the main cause of macroscopically apparent mycotic lymphadenitis, a sporadic disease most probably caused by feeding with mouldy food stuffs. ..
  20. Durkin M, Jäger A, Khurana T, Nielsen F, Albrechtsen R, Wewer U. Characterization of the human laminin beta2 chain locus (LAMB2): linkage to a gene containing a nonprocessed, transcribed LAMB2-like pseudogene (LAMB2L) and to the gene encoding glutaminyl tRNA synthetase (QARS). Cytogenet Cell Genet. 1999;84:173-8 pubmed
    ..The sequence of 1.75 kb of genomic DNA at the 3' end of LAMB2L was similar to exons 8-12 of the laminin beta2 chain gene. The LAMB2L-LAMB2-QARS cluster lies telomeric to the gene encoding the laminin-binding protein dystroglycan (DAG1). ..
  21. Amado M, Almeida R, Schwientek T, Clausen H. Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. Biochim Biophys Acta. 1999;1473:35-53 pubmed
  22. Sonne S, Hoei Hansen C, Nielsen J, Herlihy A, Andersson A, Almstrup K, et al. CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours. APMIS. 2006;114:549-58 pubmed
    ..In conclusion, despite high mRNA levels, the CDH1 protein is not expressed in CIS, suggesting translational suppression of CDH1 protein expression. CDH1 serum levels may be a serological marker for staging of TGCT patients. ..
  23. Brandt C, Simonsen H, Liptrot M, Søgaard L, Lundgren J, Ostergaard C, et al. In vivo study of experimental pneumococcal meningitis using magnetic resonance imaging. BMC Med Imaging. 2008;8:1 pubmed publisher
    ..MRI will be a valuable technique for future studies aiming at evaluating or optimizing adjunctive treatments. ..
  24. Agger E, Cassidy J, Brady J, Korsholm K, Vingsbo Lundberg C, Andersen P. Adjuvant modulation of the cytokine balance in Mycobacterium tuberculosis subunit vaccines; immunity, pathology and protection. Immunology. 2008;124:175-85 pubmed publisher
    ..This study indicates that the adjuvant component of a tuberculosis vaccine may be crucial in determining the kinetics by which effective granulomas, pivotal in controlling bacterial growth, are formed. ..
  25. Nielsen M, Christensen S, Hoffmann E. Effects of osmotic stress on the activity of MAPKs and PDGFR-beta-mediated signal transduction in NIH-3T3 fibroblasts. Am J Physiol Cell Physiol. 2008;294:C1046-55 pubmed publisher
    ..It is thus likely that cell swelling via activation of ERK1/2 and cell shrinkage via activation of the p38 and JNK pathway and inhibition of the PDGFR signaling pathway may act as key players in the regulation of tissue homeostasis. ..
  26. Bartels E, Bang C, Nielsen L. Early atherosclerosis and vascular inflammation in mice with diet-induced type 2 diabetes. Eur J Clin Invest. 2009;39:190-9 pubmed publisher
    ..Our findings suggest that diet-induced type 2 diabetes causes early atherosclerosis in the absence of dyslipidaemia, and that even a moderate level of LDL-C markedly augments this effect. ..
  27. Josefsen K, Lee Y, Thams P, Efendic S, Nielsen J. AKAP 18 alpha and gamma have opposing effects on insulin release in INS-1E cells. FEBS Lett. 2010;584:81-5 pubmed publisher
    ..The roles of AKAP 18 alpha and gamma in mediating insulin release are consistent with their respective regulations by glucose. ..
  28. Jespersen J, Nedergaard A, Andersen L, Schjerling P, Andersen J. Myostatin expression during human muscle hypertrophy and subsequent atrophy: increased myostatin with detraining. Scand J Med Sci Sports. 2011;21:215-23 pubmed publisher
  29. Lefever T, Pedersen E, Basse A, Paus R, Quondamatteo F, Stanley A, et al. N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways. J Cell Sci. 2010;123:128-40 pubmed publisher
    ..These data identify the actin nucleation regulator N-WASP as a novel element of hair-cycle control that modulates the antiproliferative and pro-apoptotic TGFbeta pathway in keratinocytes in vivo and in vitro. ..
  30. Salanti A, Resende M, Ditlev S, Pinto V, Dahlbäck M, Andersen G, et al. Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies. Malar J. 2010;9:11 pubmed publisher
    ..It is possible to induce parasite adhesion-blocking antibodies when immunizing with a number of different VAR2CSA domains. This indicates that the CSA binding site in VAR2CSA is comprised of epitopes from different domains. ..
  31. Liberti S, Andersen S, Wang J, May A, Miron S, Perderiset M, et al. Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks. DNA Repair (Amst). 2011;10:73-86 pubmed publisher
    ..Our results reveal that protein domains in hEXO1 in conjunction with specific protein interactions control bi-directional routing of hEXO1 between on-going DNA replication and repair processes in living cells. ..
  32. Møbjerg N, Halberg K, Jørgensen A, Persson D, Bjørn M, Ramløv H, et al. Survival in extreme environments - on the current knowledge of adaptations in tardigrades. Acta Physiol (Oxf). 2011;202:409-20 pubmed publisher
    ..This review summarizes the current knowledge on adaptations found among tardigrades, and presents new data on tardigrade cell numbers and osmoregulation. ..
  33. Wu H, Lee B, Yang L, Wang H, Givskov M, Molin S, et al. Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation. FEMS Immunol Med Microbiol. 2011;62:49-56 pubmed publisher
    ..aeruginosa PAO1 by airway phagocytes, but did not affect phagocytosis of a PAO1-filM mutant. Our study suggests that ginseng treatment may help to eradicate the biofilm-associated chronic infections caused by P. aeruginosa. ..
  34. Jacobsen J, Holstein Rathlou N. A life under pressure: circumferential stress in the microvascular wall. Basic Clin Pharmacol Toxicol. 2012;110:26-34 pubmed publisher
    ..The aim of this MiniReview was to outline in brief this integrative role of circumferential wall stress in the microcirculation. ..
  35. Hundahl C, Luuk H, Ilmjärv S, Falktoft B, Raida Z, Vikesaa J, et al. Neuroglobin-deficiency exacerbates Hif1A and c-FOS response, but does not affect neuronal survival during severe hypoxia in vivo. PLoS ONE. 2011;6:e28160 pubmed publisher
    ..Bioinformatic analysis of differential gene expression yielded novel predictions suggesting that chromatin remodeling and mRNA metabolism are among the key regulatory mechanisms when adapting to prolonged hypoxia. ..
  36. Zhan C, Wang J, Kolko M. Diverse regulation of retinal pigment epithelium phagocytosis of photoreceptor outer segments by calcium-independent phospholipase A?, group VIA and secretory phospholipase A?, group IB. Curr Eye Res. 2012;37:930-40 pubmed publisher
    ..No apparent interaction between iPLA(2)-VIA and sPLA(2)-IB was found. ..
  37. Podolska A, Anthon C, Bak M, Tommerup N, Skovgaard K, Heegaard P, et al. Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae. BMC Genomics. 2012;13:459 pubmed publisher
    ..Our results extend annotation of microRNA in pig and provide insight into the role of a number of microRNAs in regulation of bacteria induced immune and inflammatory response in porcine lung...
  38. Larsen E, Christiansen O, Kolte A, Macklon N. New insights into mechanisms behind miscarriage. BMC Med. 2013;11:154 pubmed publisher
    ..These new insights into the mechanisms behind miscarriage offer the prospect of novel effective interventions that may prevent this distressing condition. ..
  39. Andersson C, Kvist P, McElhinney K, Baylis R, Gram L, Pelzer H, et al. Factor XIII Transglutaminase Supports the Resolution of Mucosal Damage in Experimental Colitis. PLoS ONE. 2015;10:e0128113 pubmed publisher
  40. Mayorca Guiliani A, Madsen C, Cox T, Horton E, Venning F, Erler J. ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix. Nat Med. 2017;23:890-898 pubmed publisher
    ..The ISDoT procedure allows for the study of native ECM structure under normal and pathological conditions in unprecedented detail...
  41. Solberg H, Løber D, Eriksen J, Ploug M, Rønne E, Behrendt N, et al. Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator. Eur J Biochem. 1992;205:451-8 pubmed
    ..abstract truncated at 400 words) ..
  42. Oettinger T, Andersen A. Cloning and B-cell-epitope mapping of MPT64 from Mycobacterium tuberculosis H37Rv. Infect Immun. 1994;62:2058-64 pubmed
    ..Western blot (immunoblot) analysis revealed that the murine antibodies bind to one linear and three conformational epitopes. ..
  43. Grigorian M, Ambartsumian N, Lykkesfeldt A, Bastholm L, Elling F, Georgiev G, et al. Effect of mts1 (S100A4) expression on the progression of human breast cancer cells. Int J Cancer. 1996;67:831-41 pubmed
    ..Our results indicate that mts1 expression in human breast cancer cells induces several changes characteristic of malignant phenotype and tumor progression. ..
  44. Nissen P, Winterø A, Fredholm M. Mapping of porcine genes belonging to two different cytochrome P450 subfamilies. Anim Genet. 1998;29:7-11 pubmed
    ..The CYP2C pseudogene was mapped genetically to pig chromosome 14, using the PiGMaP shared reference pedigrees. The localisations provide information for the human/pig comparative map. ..
  45. Larsen L, Uttenthal A, Arctander P, Tjørnehøj K, Viuff B, Røntved C, et al. Serological and genetic characterisation of bovine respiratory syncytial virus (BRSV) indicates that Danish isolates belong to the intermediate subgroup: no evidence of a selective effect on the variability of G protein nucleotide sequence by prior c. Vet Microbiol. 1998;62:265-79 pubmed
    ..When combined, these data strongly suggested that the Danish isolates belong to the intermediate subgroup. ..
  46. Craven J, Bjørn H, Barnes E, Henriksen S, Nansen P. A comparison of in vitro tests and a faecal egg count reduction test in detecting anthelmintic resistance in horse strongyles. Vet Parasitol. 1999;85:49-59 pubmed
    ..Further testing is needed to confirm if these findings are truly indicative of resistance. Generally, correlations between the tests were poor and it was not possible to use the outcome of one test to predict the outcome of another...
  47. Jensen J, Mikkelsen J, Mørk A. Increased adenylyl cyclase type 1 mRNA, but not adenylyl cyclase type 2 in the rat hippocampus following antidepressant treatment. Eur Neuropsychopharmacol. 2000;10:105-11 pubmed
    ..This may indicate enhanced AC/G protein coupling. Thus, citalopram may increase cAMP signalling by acting on components of the AC system without affecting the protein level of the AC type 1. ..
  48. Cazzamali G, Saxild N, Grimmelikhuijzen C. Molecular cloning and functional expression of a Drosophila corazonin receptor. Biochem Biophys Res Commun. 2002;298:31-6 pubmed
    ..Furthermore, a receptor that is structurally very similar to the Drosophila corazonin receptor can be found in the genomic database from the malaria mosquito Anopheles gambiae. ..
  49. Pedersen M, Tkach V, Pedersen N, Berezin V, Poulsen H. Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility. Int J Cancer. 2004;108:643-53 pubmed
    ..Overall these results indicate that tumor-associated EGFR mutations might be critical for tumor cell motility, invasion and thus progression of disease. ..
  50. Pasini D, Bracken A, Hansen J, Capillo M, Helin K. The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol Cell Biol. 2007;27:3769-79 pubmed
    ..Furthermore, we provide evidence that PcGs have different mechanisms to regulate transcription during cellular differentiation. ..
  51. Nielsen S, Møllgård K, Clement C, Veland I, Awan A, Yoder B, et al. Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines. Dev Dyn. 2008;237:2039-52 pubmed publisher
    ..These findings indicate that primary cilia are involved in pancreatic development and postnatal tissue homeostasis...
  52. Nielsen B, Egeblad M, Rank F, Askautrud H, Pennington C, Pedersen T, et al. Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. PLoS ONE. 2008;3:e2959 pubmed publisher
    ..Our results suggest that MMP13 is a marker of carcinoma-associated myofibroblasts of invasive carcinoma, even though it does not make a major contribution to tumor progression in the MMTV-PyMT breast cancer model. ..
  53. Cremer S, Ugelvig L, Drijfhout F, Schlick Steiner B, Steiner F, Seifert B, et al. The evolution of invasiveness in garden ants. PLoS ONE. 2008;3:e3838 pubmed publisher
  54. Boutrup T, Boesen H, Boye M, Agerholm J, Jensen T. Early pathogenesis in porcine proliferative enteropathy caused by Lawsonia intracellularis. J Comp Pathol. 2010;143:101-9 pubmed publisher
  55. Mathiasen D, Egebjerg C, Andersen S, Rafn B, Puustinen P, Khanna A, et al. Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation. Oncogene. 2012;31:390-401 pubmed publisher
    ..Thus, these data identify the key signal converging point of JNK2 and ERK pathways and underline the central role of CIP2A in ras transformation. ..
  56. Andreasen J, Redrobe J, Nielsen E. Combined ?7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: a comparison of SSR180711 and PNU-282987. Pharmacol Biochem Behav. 2012;100:624-9 pubmed publisher
    ..The addition of ?7 nAChR agonism to classical monoamine-based mechanisms may represent a novel option for the improved treatment of major depression. ..
  57. Turner L, Lavstsen T, Berger S, Wang C, Petersen J, Avril M, et al. Severe malaria is associated with parasite binding to endothelial protein C receptor. Nature. 2013;498:502-5 pubmed publisher
    ..falciparum cytoadhesion to a host receptor involved in anticoagulation and endothelial cytoprotective pathways, and has implications for understanding malaria pathology and the development of new malaria interventions. ..
  58. Jäderlund K, Rohdin C, Berendt M, Stigen Ø, Fredholm M, Espenes A, et al. Re-emergence of hereditary polyneuropathy in Scandinavian Alaskan malamute dogs-old enemy or new entity? A case series. Acta Vet Scand. 2017;59:26 pubmed publisher
  59. Skaanild M, Friis C. Is cytochrome P450 CYP2D activity present in pig liver?. Pharmacol Toxicol. 2002;91:198-203 pubmed
    ..These results indicate that dextromethorphan and bufuralol metabolism may be catalysed by CYP2B and not CYP2D. ..
  60. Hammerum A, Heuer O, Emborg H, Bagger Skjøt L, Jensen V, Rogues A, et al. Danish integrated antimicrobial resistance monitoring and research program. Emerg Infect Dis. 2007;13:1632-9 pubmed publisher
  61. Jacobsen B, Ploug M. The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition. Curr Med Chem. 2008;15:2559-73 pubmed
    ..This review will evaluate structural-functional and disease-related aspects of uPAR and C4.4A with a view to possible pharmacological targeting strategies for therapy and for non-invasive bioimaging. ..
  62. Christensen D, Gysemans C, Lundh M, Dahllöf M, Noesgaard D, Schmidt S, et al. Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and ?-cell protection. Proc Natl Acad Sci U S A. 2014;111:1055-9 pubmed publisher
    ..These effects were associated with NF-?B subunit p65 hyperacetylation. Taken together, these data provide a rationale for clinical trials of safety and efficacy of KDACi in patients with autoimmune disease such as type 1 diabetes. ..
  63. Nagler C, Hörnig M, Haug J, Noever C, Høeg J, Glenner H. The bigger, the better? Volume measurements of parasites and hosts: Parasitic barnacles (Cirripedia, Rhizocephala) and their decapod hosts. PLoS ONE. 2017;12:e0179958 pubmed publisher
  64. Kriajevska M, Cardenas M, Grigorian M, Ambartsumian N, Georgiev G, Lukanidin E. Non-muscle myosin heavy chain as a possible target for protein encoded by metastasis-related mts-1 gene. J Biol Chem. 1994;269:19679-82 pubmed
    ..The data suggest that the target for Mts-1 protein is a heavy chain of non-muscle myosin. ..
  65. Angen O, Quirie M, Donachie W, Bisgaard M. Investigations on the species specificity of Mannheimia (Pasteurella) haemolytica serotyping. Vet Microbiol. 1999;65:283-90 pubmed
    ..haemolytica or M. glucosida. These observations emphasize that extended phenotypic and genetic characterization is necessary for the proper identification of these organisms. ..
  66. Jungersen G, Eriksen L, Nansen P, Lind P, Rasmussen T, Meeusen E. Regional immune responses with stage-specific antigen recognition profiles develop in lymph nodes of pigs following Ascaris suum larval migration. Parasite Immunol. 2001;23:185-94 pubmed
    ..These observations demonstrate how development of distinct regional immune responses in tissues with different antigen stimulation can be monitored with ASC-probes and flow cytometry. ..
  67. Olsen C, Hogg S, Lapiz M. Tonic immobility in guinea pigs: a behavioural response for detecting an anxiolytic-like effect?. Behav Pharmacol. 2002;13:261-9 pubmed
  68. Hughes W, Eilenberg J, Boomsma J. Trade-offs in group living: transmission and disease resistance in leaf-cutting ants. Proc Biol Sci. 2002;269:1811-9 pubmed
    ..Unlike most organisms, group living in these ants may actually be associated with a net benefit in terms of disease dynamics. ..
  69. Villesen H, Foster D, Upton R, Somogyi A, Martinez A, Grant C. Cerebral kinetics of oxycodone in conscious sheep. J Pharm Sci. 2006;95:1666-76 pubmed
    ..3% after 45 min. In conclusion, pharmacokinetic modelling of oxycodone showed a delayed equilibration between brain and blood of a nature that would be affected by changes in both CBF and blood brain barrier permeability. ..
  70. Stegmann A, Hansen M, Wang Y, Larsen J, Lund L, Ritie L, et al. Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation. Physiol Genomics. 2006;27:141-55 pubmed
    ..Our approach also identifies transcription factors of importance for crypt functions such as DNA replication (E2F) and stem cell maintenance (c-Myc). ..
  71. Dalsgaard M, Madsen F, Secher N, Laursen H, Quistorff B. High glycogen levels in the hippocampus of patients with epilepsy. J Cereb Blood Flow Metab. 2007;27:1137-41 pubmed
  72. Schöllkopf C, Melbye M, Munksgaard L, Smedby K, Rostgaard K, Glimelius B, et al. Borrelia infection and risk of non-Hodgkin lymphoma. Blood. 2008;111:5524-9 pubmed publisher
    ..2 [2.0-8.9]). Our observations suggest a previously unreported association between B. burgdorferi infection and risk of mantle cell lymphoma. ..
  73. Hansen K, Brauner Osborne H. Xenopus oocyte electrophysiology in GPCR drug discovery. Methods Mol Biol. 2009;552:343-57 pubmed publisher
    ..We will focus on the detection of GPCR activation by recordings of currents through CaCCs that are activated by calcium release from the endoplasmic reticulum and thus the G(q) signaling pathway. ..
  74. Schøller J, Singh M, Bergmeier L, Brunstedt K, Wang Y, Whittall T, et al. A recombinant human HLA-class I antigen linked to dextran elicits innate and adaptive immune responses. J Immunol Methods. 2010;360:1-9 pubmed publisher
    ..These adaptive and innate immune responses induced by a novel recombinant HLA construct in human cells and mice suggest their application as a potential vaccine candidate against HIV infection. ..
  75. Skytt D, Madsen K, Pajęcka K, Schousboe A, Waagepetersen H. Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex. Neurochem Res. 2010;35:2043-52 pubmed publisher
    ..This provides flexibility with regard to preparation and use of these cultures for a variety of purposes. ..
  76. Bengtsson A, Joergensen L, Rask T, Olsen R, Andersen M, Turner L, et al. A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies. J Immunol. 2013;190:240-9 pubmed publisher
  77. Lewin E, Garfia B, Almaden Y, Rodriguez M, Olgaard K. Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic rats. Kidney Int. 2003;64:63-70 pubmed
    ..Thus, it is hypothesized that PTH during hypocalcemia might have a positive auto-feedback regulatory role on its own secretion. ..
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