Experts and Doctors on animals in Hangzhou, Zhejiang Sheng, China


Locale: Hangzhou, Zhejiang Sheng, China
Topic: animals

Top Publications

  1. Zhang X, Zhou J, Wu Y, Zheng X, Ma G, Wang Z, et al. Differential proteome analysis of host cells infected with porcine circovirus type 2. J Proteome Res. 2009;8:5111-9 pubmed publisher
  2. Ying M, Zhou X, Zhong L, Lin N, Jing H, Luo P, et al. Bortezomib sensitizes human acute myeloid leukemia cells to all-trans-retinoic acid-induced differentiation by modifying the RAR?/STAT1 axis. Mol Cancer Ther. 2013;12:195-206 pubmed publisher
    ..Taken together, our study was the first to evaluate bortezomib and ATRA synergy in AML cell differentiation and to assess new opportunities for bortezomib and ATRA combination as a promising approach for future differentiation therapy. ..
  3. Lü L, Li J, Yew D, Rudd J, Mak Y. Oxidative stress on the astrocytes in culture derived from a senescence accelerated mouse strain. Neurochem Int. 2008;52:282-9 pubmed
    ..Our results suggested that the changes of astrocytes in peroxide detoxification may play a role in aging of the central nervous system, and further aging studies should examine the oxidative status of the samples. ..
  4. Xie Y, Ye Y, Sun H, Li D. Contribution of the glycidic moieties to the haemolytic and adjuvant activity of platycodigenin-type saponins from the root of Platycodon grandiflorum. Vaccine. 2008;26:3452-60 pubmed publisher
  5. Zhang X, Xu H, Jiang Y, Yu S, Cai Y, Lu B, et al. Influence of dexamethasone on mesenteric lymph node of rats with severe acute pancreatitis. World J Gastroenterol. 2008;14:3511-7 pubmed
    ..To study the influence and mechanisms of dexamethasone on mesenteric lymph node of rats with severe acute pancreatitis (SAP)...
  6. Luo Q, Zhou Q, Yu X, Lin H, Hu S, Yu J. Genome-wide mapping of conserved microRNAs and their host transcripts in Tribolium castaneum. J Genet Genomics. 2008;35:349-55 pubmed publisher
    ..A hypothetical feedback model has been proposed based on the analysis of the relationship between intronic miRNAs and their host genes in the development of red flour beetle...
  7. Gu Q, Song D, Zhu M. Oral vaccination of mice against Helicobacter pylori with recombinant Lactococcus lactis expressing urease subunit B. FEMS Immunol Med Microbiol. 2009;56:197-203 pubmed publisher
    ..pylori strain SS1. In conclusion, mucosal vaccination with L. lactis expressing UreB produced serum IgG and UreB-specific fecal IgA, and prevented gastric infection with H. pylori. ..
  8. Shen L, Ding M, Zhang L, Jin F, Zhang W, Li D. Expression of Acc-Royalisin gene from royal jelly of Chinese honeybee in Escherichia coli and its antibacterial activity. J Agric Food Chem. 2010;58:2266-73 pubmed publisher
    ..MAR peptide released from the thrombin-cleaved GST-MAR fusion protein has a stronger antibacterial activity than that of GST-MAR fusion protein. ..
  9. Fan Y, Sun P, Wang Y, He X, Deng X, Chen X, et al. The G protein-coupled receptors in the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2010;40:581-91 pubmed publisher
    ..mori, which may be related to its long history of domestication. Moreover, the presence of many Bombyx-specific GPCRs suggests that neither Drosophila nor Anopheles is good representatives for the GPCRs in the Class Insecta. ..

More Information

Publications926 found, 100 shown here

  1. Chen L, Lei L, Ding P, Tang Q, Wu Y. Osteogenic effect of Drynariae rhizoma extracts and Naringin on MC3T3-E1 cells and an induced rat alveolar bone resorption model. Arch Oral Biol. 2011;56:1655-62 pubmed publisher
    ..To investigate if Drynariae rhizoma (DR) and its main ingredient Naringin could reduce alveolar bone loss by stimulating the proliferation and differentiation of osteoblasts...
  2. Liu J, Yang Y, Zhuang S, Yang Y, Li F, Liu W. Enantioselective endocrine-disrupting effects of bifenthrin on hormone synthesis in rat ovarian cells. Toxicology. 2011;290:42-9 pubmed publisher
    ..Our findings suggest that the enantioselective toxicity of chiral pesticides should be considered for evaluating mammalian reproductive health, a toxicologic endpoint of great concern in health risk assessment. ..
  3. Yao H, Zhang L, Shen J, Shen H, Jia Y, Yan X, et al. Cyptoporus polysaccharide prevents lipopolysaccharide-induced acute lung injury associated with down-regulating Toll-like receptor 2 expression. J Ethnopharmacol. 2011;137:1267-74 pubmed publisher
    ..Our results supported a protective role of CP in ALI and suggested that the reduction of the activation of TLR(2) and NF-?B signal pathway in lung injury may be relavant to the pretreatment of CP. ..
  4. Su Y, Li J, Li M, Luan J, Ye X, Wang X, et al. Transcriptomic analysis of the salivary glands of an invasive whitefly. PLoS ONE. 2012;7:e39303 pubmed publisher
    ..Our findings provide substantial sequence information for the primary salivary glands of whiteflies and will be the basis for future studies on whitefly-plant interactions and virus transmission. ..
  5. Tu W, Niu L, Liu W, Xu C. Embryonic exposure to butachlor in zebrafish (Danio rerio): endocrine disruption, developmental toxicity and immunotoxicity. Ecotoxicol Environ Saf. 2013;89:189-95 pubmed publisher
    ..Bidirectional interactions between the endocrine system and the immune system might be present, and further studies are needed to determine these possible pathways. ..
  6. Zhang Y, Li C, Liu C, Chen K. Prevention of losses for hog farmers in China: insurance, on-farm biosecurity practices, and vaccination. Res Vet Sci. 2013;95:819-24 pubmed publisher
    ..However, we also find a moral hazard effect in that higher premium expenditures by the insured households might induce larger loss ratios. ..
  7. Jiang W, Ye P, Chen C, Wang K, Liu P, He S, et al. Two novel hepatocellular carcinoma cycle inhibitory cyclodepsipeptides from a hydrothermal vent crab-associated fungus Aspergillus clavatus C2WU. Mar Drugs. 2013;11:4761-72 pubmed publisher
  8. Chen W, Zhang Y, Li Y, Zhang J, Zhang T, Fu B, et al. Constitutive expression of Wnt/β‑catenin target genes promotes proliferation and invasion of liver cancer stem cells. Mol Med Rep. 2016;13:3466-74 pubmed publisher
    ..Therefore, these data suggest that Wnt/β‑catenin signaling is a potential therapeutic target to reduce CSC‑mediated tumorigenicity and invasion in liver cancer. ..
  9. Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, et al. USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling. EMBO J. 2017;36:1623-1639 pubmed publisher
    ..Moreover, zebrafish depleted of USP4 exhibited defective cell migration and slower coordinated cell movement known as epiboly, both of which could be rescued by SMAD4. Therefore, USP4 is a critical determinant of SMAD4 activity. ..
  10. Wang Q, Li N, Wang X, Shen J, Hong X, Yu H, et al. Membrane protein hMYADM preferentially expressed in myeloid cells is up-regulated during differentiation of stem cells and myeloid leukemia cells. Life Sci. 2007;80:420-9 pubmed
  11. Qu F, Zhou J, Burrows E, Luo Q, Wu Y, Wang T, et al. Acupuncture may improve the absorption of baicalin from the extracts of Scutellaria baicalensis Georgi in rats with pelvic inflammation. Forsch Komplementmed. 2008;15:282-5 pubmed publisher
  12. Jin X, Yang Y, Chen K, Lv Z, Zheng L, Liu Y, et al. HDMCP uncouples yeast mitochondrial respiration and alleviates steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels: a novel mechanism for NAFLD. J Hepatol. 2009;50:1019-28 pubmed publisher
    ..More importantly, HDMCP might become a novel drug target for its ability in alleviating hepatic steatosis. ..
  13. Lou Y, Zhou K, Shi J, Pan D. Characterizing the binding interaction of fungicide boscalid with bovine serum albumin (BSA): A spectroscopic study in combination with molecular docking approach. J Photochem Photobiol B. 2017;173:589-597 pubmed publisher
  14. Du W, Ji X, Shine R. Does body volume constrain reproductive output in lizards?. Biol Lett. 2005;1:98-100 pubmed
    ..Our surgical manipulations show that the amount of space available to hold eggs within a female's abdomen influences her total reproductive allocation, enabling her to flexibly modify her reproductive output as she grows larger. ..
  15. Jin Y, Chen R, Sun L, Liu W, Fu Z. Photoperiod and temperature influence endocrine disruptive chemical-mediated effects in male adult zebrafish. Aquat Toxicol. 2009;92:38-43 pubmed publisher
    ..These results suggest that temperature and photoperiod could confound the risk assessment of estrogenic chemicals, and they also have potential implications for future environmental monitoring studies. ..
  16. Xie Y, Luan C, Zhang H, Han F, Feng J, Choi Y, et al. Effects of thioredoxin: SUMO and intein on soluble fusion expression of an antimicrobial peptide OG2 in Escherichia coli. Protein Pept Lett. 2013;20:54-60 pubmed
    ..The OG2 released by both tobacco etch virus protease and enterokinase from Trx-OG2 showed strong antimicrobial activity against Staphylococcus aureus ATCC25923. ..
  17. Wang X, Wang Y, Li Y. Adipose triglyceride lipase (ATGL) clone, expression pattern, and regulation by different lipid sources and lipid levels in large yellow croaker (Pseudosciaena crocea R.). Mar Biotechnol (NY). 2013;15:197-205 pubmed publisher
    ..01). Fish in soybean oil group exhibited significantly lower ATGL expression than fish in the fish oil and beef tallow groups (P?<?0.01). These data enhance our understanding of ATGL in fish lipid metabolism. ..
  18. Shentu X, Li D, Xu J, She L, Yu X. Effects of fungicides on the yeast-like symbiotes and their host, Nilaparvata lugens Stål (Hemiptera: Delphacidae). Pestic Biochem Physiol. 2016;128:16-21 pubmed publisher
    ..It implies that using specific fungicides as an additive to imidacloprid for controlling BPH could be a novel way to enhance the efficacy of insecticide, minimizing the use of imidacloprid in paddy fields. ..
  19. Zhao T, Bernstein K, Fang J, Shen X. Angiotensin-converting enzyme affects the presentation of MHC class II antigens. Lab Invest. 2017;97:764-771 pubmed publisher
    ..Thus, ACE is a dynamic participant in processing MHC class II peptides. Manipulation of ACE expression by antigen-presenting cells may prove to be a novel strategy to alter the immune response. ..
  20. Ye T, Ye Z, Gao Q, Xia Q. [Cardioprotection of mitoSlo1 channel activation involves mitochondrial permeability transition in ischemia and reperfusion of rat hearts]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2005;34:441-6 pubmed
    ..MitoSlo(1) channel activation by NS1619 protects the myocardium against ischemia and reperfusion injury by inhibiting mitochondrial permeability transition pore opening. ..
  21. Ye G, Dong S, Song Q, Shi M, Chen X, Hu C. Molecular cloning and developmental expression of the vitellogenin gene in the endoparasitoid, Pteromalus puparum. Insect Mol Biol. 2008;17:227-33 pubmed publisher
    ..The haemolymph Vg titre appeared 24 h after the appearance of Vg transcript. A positive correlation between the titre and transcript level of Vg in individual female wasps was found. ..
  22. Li W, Ji Z, Zhuo G, Xu R, Wang J, Jiang H. Effects of a selective cyclooxygenase-1 inhibitor in SKOV-3 ovarian carcinoma xenograft-bearing mice. Med Oncol. 2010;27:98-104 pubmed publisher
    ..COX-1, not COX-2, protein levels are elevated in tumor tissues. These findings may implicate COX-1 as a suitable target for the treatment of ovarian cancer and that antiangiogenic therapy can be used to inhibit ovarian cancer growth. ..
  23. Zhu F, Du H, Miao Z, Quan H, Xu Z. Protection of Procambarus clarkii against white spot syndrome virus using inactivated WSSV. Fish Shellfish Immunol. 2009;26:685-90 pubmed publisher
    ..These results indicate the protective efficacy of BEI-inactivated WSSV lies on the integrity of envelope proteins of WSSV and the possibility of BEI-inactivated WSSV to protect P. clarkii from WSSV...
  24. Tao Y, Wang Y. Bioactive sesquiterpenes isolated from the essential oil of Dalbergia odorifera T. Chen. Fitoterapia. 2010;81:393-6 pubmed publisher
    ..The results showed that the antithrombotic activity of these two compounds was poor, while their anti-platelet activity was strong at middle and high concentrations...
  25. Dai Z, Li R, Dai L, Yang J, Chen S, Zeng Q, et al. Determination in oocytes of the reproductive modes for the brine shrimp Artemia parthenogenetica. Biosci Rep. 2011;31:17-30 pubmed publisher
    ..In summary, our results provide evidence at the molecular level that the reproductive mode of Artemia is already determined at the oocyte stage of their life cycle...
  26. Zhang W, Shen Q, Shen J. [Expression of neural salient serine-/arginine-rich protein 1 (NSSR1) in colorectal cancer]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2011;40:540-4 pubmed
    ..In colorectal cancer, NSSR1 was highly expressed in the nucleus of tumor cells. The extensive expression of NSSR1 in colorectal cancer cells may hint it's roles in the biological function of colorectal cancer. ..
  27. Luo P, Lin M, Li L, Yang B, He Q. The proteasome inhibitor bortezomib enhances ATRA-induced differentiation of neuroblastoma cells via the JNK mitogen-activated protein kinase pathway. PLoS ONE. 2011;6:e27298 pubmed publisher
    ..These findings provide the rationale for the development of a new therapeutic strategy for NB based on the pharmacological combination of ATRA and bortezomib. ..
  28. Li K, Lu Y, Xu Z, Zhang J, Zhu J, Zhang J, et al. Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy. Nat Neurosci. 2011;15:267-73 pubmed publisher
    ..Together, our findings suggest that NRG1-ErbB4 signaling contributes to human epilepsy through regulating the excitability of FS-PV interneurons. ErbB4 may be a new target for anticonvulsant drugs in epilepsy. ..
  29. Zhao M, Li L, Sun D, Sun S, Huang S, Zeng S, et al. Stereoselective metabolism of tetrahydropalmatine enantiomers in rat liver microsomes. Chirality. 2012;24:368-73 pubmed publisher
    ..The results suggested that THP enantiomers were predominately metabolized by CYP3A1/2 and CYP1A2 in RLM, and CYP3A1/2 preferred to metabolize (+)-THP, whereas CYP1A2 preferred (-)-THP...
  30. Bin G, Jiarong Z, Shihao W, Xiuli S, Cheng X, Liangbiao C, et al. Aire promotes the self-renewal of embryonic stem cells through Lin28. Stem Cells Dev. 2012;21:2878-90 pubmed publisher
    ..These functions reveal novel perspectives for studying the molecular mechanisms behind the establishment and sustenance of pluripotent identity. ..
  31. Taki Eldin A, Zhou L, Xie H, Zheng S. Liver regeneration after liver transplantation. Eur Surg Res. 2012;48:139-53 pubmed publisher
    ..However, further research is essential to reveal the complex processes affecting liver regeneration, which may provide novel strategies in the management of liver transplantation recipients and donors. ..
  32. Shi W, Qi L, Fang S, Lu Y, Zhang W, Wei E. Aggravated chronic brain injury after focal cerebral ischemia in aquaporin-4-deficient mice. Neurosci Lett. 2012;520:121-5 pubmed publisher
    ..Therefore, AQP4 deficiency complicated by astrocyte dysfunction aggravates chronic brain injury after focal cerebral ischemia, suggesting that AQP4 may be important in the chronic phase of the post-ischemic recovery process. ..
  33. Liu D, Trojanowicz B, Ye L, Li C, Zhang L, Li X, et al. The invasion and metastasis promotion role of CD97 small isoform in gastric carcinoma. PLoS ONE. 2012;7:e39989 pubmed publisher
  34. Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, et al. Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. Nat Immunol. 2014;15:612-22 pubmed publisher
    ..Our data identify Rhbdd3 as a critical regulator of DC activation and indicate K27-linked polyubiquitination is a potent ubiquitin-linked pattern involved in the control of autoimmunity. ..
  35. Shan L, Gao J, Zhang Y, Shen S, He Y, Wang J, et al. Proteomic characterization and comparison of venoms from two elapid snakes (Bungarus multicinctus and Naja atra) from China. J Proteomics. 2016;138:83-94 pubmed publisher
    ..Elucidation of the proteomic profiles of these snake venoms is helpful in understanding composition-function relationships and will facilitate the clinical application of antivenoms. ..
  36. Chen Z, Ye Z, Shi Q. [Rat microsomal glutathione S-transferase 1 alters cytotoxic effects of chlorambucil on PC-3, K562, HepG2 and P388D1 cell lines]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007;36:236-40 pubmed
    ..The CHB-induced apoptosis on PC-3 and K562 cell lines altered by mGST1 was confirmed using DeltaPsim examination, JC-1 or AO/EB staining. mGST1 can reduce the cytotoxic effects of CHB in selected cancer cell lines. ..
  37. Xiao X, Yang W. Actin-based dynamics during spermatogenesis and its significance. J Zhejiang Univ Sci B. 2007;8:498-506 pubmed
  38. Qin F, Sun H. Immunosuppressive activity of the ethanol extract of Sedum sarmentosum and its fractions on specific antibody and cellular responses to ovalbumin in mice. Chem Biodivers. 2008;5:2699-709 pubmed publisher
    ..The results suggest that EESS could suppress the cellular and humoral immune response in mice, and deserve further research to be developed as immunosuppressant...
  39. Zhu X, Dai J, Tan X, Zhao Y, Yang W. Activation of an AMP-activated protein kinase is involved in post-diapause development of Artemia franciscana encysted embryos. BMC Dev Biol. 2009;9:21 pubmed publisher
  40. Xu Z, Yang Y, Gui Q, Zhang L, Hu L. Expression, purification, and characterization of recombinant lumbrokinase PI239 in Escherichia coli. Protein Expr Purif. 2010;69:198-203 pubmed publisher
    ..The purified and renatured rLK apparently ameliorated the conditions of the model thrombosis rats used, and may be developed into a therapeutic agent for thrombotic-associated diseases...
  41. Jiang Y, Shang H, Xu H, Ding X, Zhao L, Fang L, et al. Detection and genotyping of porcine circovirus in naturally infected pigs by oligo-microarray. Res Vet Sci. 2010;89:133-9 pubmed publisher
    ..Our results indicated that the oligonucleotide array is useful for the identification and discrimination of PCV from clinical isolates and specimens in a clinical laboratory. ..
  42. Shi J, Zhang X, Jiang H. 2-(penta-1,3-diynyl)-5-(3,4-dihydroxybut-1-ynyl)thiophene, a novel NQO1 inducing agent from Echinops grijsii Hance. Molecules. 2010;15:5273-81 pubmed publisher
    ..Further investigations indicated that the activation of Keap1-Nrf2 pathway by PDDYT might be attributed to the activation of Akt and depleting the cellular glutathione (GSH). ..
  43. Wu B, Shao Y, Chen B, Liu C, Xue Z, Wu P, et al. Identification of a novel mouse brachyury (T) allele causing a short tail mutation in mice. Cell Biochem Biophys. 2010;58:129-35 pubmed publisher
    ..The T(shao) mutation is a result of a deletion in exon 2 causing the early termination and loss of function of protein encoded by the T gene, manifesting as a short tail phenotype. ..
  44. Peng G, Yuan Y, He Q, Wu W, Luo B. MicroRNA let-7e regulates the expression of caspase-3 during apoptosis of PC12 cells following anoxia/reoxygenation injury. Brain Res Bull. 2011;86:272-6 pubmed publisher
    ..These results indicate that let-7e may protect PC12 cells against apoptosis following A/R injury by negatively regulating the expression of Casp3. ..
  45. Liu X, Wang J. Iridoid glycosides fraction of Folium syringae leaves modulates NF-?B signal pathway and intestinal epithelial cells apoptosis in experimental colitis. PLoS ONE. 2011;6:e24740 pubmed publisher
    ..The aim of this study was to investigate whether IG modulates the inflammatory response in experimental colitis at the level of NF-?B signal pathway and epithelial cell apoptosis...
  46. Hu X, Li Y, Li C, Fu Y, Cai F, Chen Q, et al. Combination of fucoxanthin and conjugated linoleic acid attenuates body weight gain and improves lipid metabolism in high-fat diet-induced obese rats. Arch Biochem Biophys. 2012;519:59-65 pubmed publisher
  47. Zhang L, Zhang C, Ojcius D, Sun D, Zhao J, Lin X, et al. The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals. Mol Microbiol. 2012;83:1006-23 pubmed publisher
    ..Blockade of the two integrins or the Mce protein decreased leptospiral adherence and invasiveness. The results showed that Mce is an RGD-motif-dependent virulence factor in pathogenic Leptospira species...
  48. Du L, Wu C, Liu Q, Huang L, Wang P. Recent advances in olfactory receptor-based biosensors. Biosens Bioelectron. 2013;42:570-80 pubmed publisher
    ..We will also elaborate on various OR-based biosensors and their latest developments. Finally, current research trends and future challenges in this field will be discussed. ..
  49. Liu X, Huang N, Li H, Jin Q, Ji J. Surface and size effects on cell interaction of gold nanoparticles with both phagocytic and nonphagocytic cells. Langmuir. 2013;29:9138-48 pubmed publisher
    ..It demonstrates that cell interaction between nanoparticles and cells is not only affected by surface and size factors but also strongly depends on cell types. ..
  50. Wan Q, Pan S, Hu L, Zhu Y, Xu P, Xia J, et al. Genome analysis and signature discovery for diving and sensory properties of the endangered Chinese alligator. Cell Res. 2013;23:1091-105 pubmed publisher
    ..Finally, population history analysis indicated population admixture 0.60-1.05 million years ago, when the Qinghai-Tibetan Plateau was uplifted. ..
  51. Zhu Y, Wan Q, Yu B, Ge Y, Fang S. Patterns of genetic differentiation at MHC class I genes and microsatellites identify conservation units in the giant panda. BMC Evol Biol. 2013;13:227 pubmed publisher
    ..We also recommended 3 possible AUs based on MHC loci: Qinling, Minshan-Qionglai, and Daxiangling-Xiaoxiangling-Liangshan. Furthermore, we recommend that a captive breeding program be considered for the Qinling panda population. ..
  52. Wang D, Su L, Wang Y, Yang D, Sun C, Zhou L, et al. Long-term potentiation at cerebellar parallel fiber-Purkinje cell synapses requires presynaptic and postsynaptic signaling cascades. J Neurosci. 2014;34:2355-64 pubmed publisher
    ..In addition, NO of sufficient amplitude decides between the weakening and strengthening of PF-PC synapses. ..
  53. Jiang Z, Hu M, Ma X, Schatten H, Fan H, Wang Z, et al. LKB1 acts as a critical gatekeeper of ovarian primordial follicle pool. Oncotarget. 2016;7:5738-53 pubmed publisher
  54. Liu A, Xue G, Sun M, Shao H, Ma C, Gao Q, et al. 3D Printing Surgical Implants at the clinic: A Experimental Study on Anterior Cruciate Ligament Reconstruction. Sci Rep. 2016;6:21704 pubmed publisher
    ..Overall, the results of this study demonstrate that fabricating surgical implants at the clinic (fab@clinic) with D3DPs can be feasible, effective, and economical. ..
  55. Wang S, Zhu X, Li Q, Wang R, Wang X. Damage-tolerance strategies for nacre tablets. J Struct Biol. 2016;194:199-204 pubmed publisher
    ..The synergistic action of the nanoscale deformation mechanisms increases the energy dissipation efficiency of the tablets and contributes to the preservation of the structural and functional integrity of the shell. ..
  56. Jiang K, Gao F, Shui Q, Yu Z, Xia Z. Effect of diazoxide on regulation of vesicular and plasma membrane GABA transporter genes and proteins in hippocampus of rats subjected to picrotoxin-induced kindling. Neurosci Res. 2004;50:319-29 pubmed
  57. Wang J, Zhang X, Zhang H. [The study of thrombospondin-I (TSP1) expression in the early stages of diabetic retinopathy induced by streptozotocin]. Fen Zi Xi Bao Sheng Wu Xue Bao. 2006;39:431-7 pubmed
    ..The upregulation of TSP1 in retinas of diabetic rats suggests a role in experimental diabetic retinopathy. Further studies should address the possible involvement of the TSP1 in the pathophysiology of diabetic retinopathy. ..
  58. Zhang Y, Wang X, Xiang Z, Li H, Qiu J, Sun Q, et al. Promotion of cellular migration and apoptosis resistance by a mouse eye-specific phosphatidylethanolamine-binding protein. Int J Mol Med. 2007;19:55-63 pubmed
    ..Considering that mPEBP4 is specifically expressed in retinal ganglion cells, whether mPEBP4 is an important molecule involved in visual function needs to be further investigated. ..
  59. Ding L, Liang X, Lou Y. Time-dependence of cardiomyocyte differentiation disturbed by peroxisome proliferator-activated receptor alpha inhibitor GW6471 in murine embryonic stem cells in vitro. Acta Pharmacol Sin. 2007;28:634-42 pubmed
    ..Taken together, these results showed a close association between PPAR alpha and cardiomyocyte differentiation in vitro, and p38 MAPK was partly responsible for the regulation of PPAR alpha. ..
  60. Zha L, Wang M, Xu Z, Gu L. Efficacy of chromium(III) supplementation on growth, body composition, serum parameters, and tissue chromium in rats. Biol Trace Elem Res. 2007;119:42-50 pubmed
    ..The results indicate that chromium nanocomposite has higher efficacy on growth and body composition compared to the traditional chromium agents. ..
  61. Bao Y, Lv Z, Liu Z, Xue J, Xu Y, Zhang C. Comparative analysis of Bombyx mori nucleopolyhedrovirus responsive genes in fat body and haemocyte of B. mori resistant and susceptible strains. Insect Mol Biol. 2010;19:347-58 pubmed publisher
    ..Our results suggest that these genes may have potential roles in B. mori antiviral infection mechanisms...
  62. He P, Zhang Y, Yao Y, Tang Y, Nan X. The graphical representation of protein sequences based on the physicochemical properties and its applications. J Comput Chem. 2010;31:2136-42 pubmed publisher
    ..And, the examination of the similarity among sequences of the ND5 proteins of nine species shows the utility of our approach. ..
  63. Xiang L, He D, Dong W, Zhang Y, Shao J. Deep sequencing-based transcriptome profiling analysis of bacteria-challenged Lateolabrax japonicus reveals insight into the immune-relevant genes in marine fish. BMC Genomics. 2010;11:472 pubmed publisher
    ..Results can contribute to the in-depth study of candidate genes in marine fish immunity, and help improve current understanding of host-pathogen interactions and evolutionary history of immunogenetics from fish to mammals. ..
  64. Zhang F, Ma L, Wang W, Qian L, Yang M, Yu J, et al. Hypercholesterolemia abrogates sevoflurane-induced delayed preconditioning against myocardial infarct in rats by alteration of nitric oxide synthase signaling. Shock. 2012;37:485-91 pubmed publisher
  65. Lv X, Zhou H. Resveratrol protects H9c2 embryonic rat heart derived cells from oxidative stress by inducing autophagy: role of p38 mitogen-activated protein kinase. Can J Physiol Pharmacol. 2012;90:655-62 pubmed publisher
    ..Furthermore, the protective effects of resveratrol were inhibited by 10 µmol/L SB202190. Thus, resveratrol protected H(2)O(2)-treated H9c2 cells by upregulating autophagy via the p38 MAPK pathway. ..
  66. Zhang M, Cheng R, Lou Y, Ye W, Zhang T, Fan X, et al. Disruption of Bombyx mori nucleopolyhedrovirus ORF71 (Bm71) results in inefficient budded virus production and decreased virulence in host larvae. Virus Genes. 2012;45:161-8 pubmed publisher
    ..Taken together, these results suggest that Bm71 has important implications for determining BV yield and virulence in viral life cycle even though it is not an essential gene for replication of BmNPV. ..
  67. Zheng B, Zhou L, Zhao Q, Zhang X, Zhu D. [Expression of metabotropic glutamate receptor 4 in cardiomyocytes differentiated from mouse embryonic stem cells in vitro]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2012;41:366-72 pubmed
    ..The expression of mGluR4 is down-regulated in the cardiomyocyte differentiation of ES cells. The trend of expression is consistent with that in the prenatal mouse heart development. ..
  68. Xue J, Zhang X, Xu H, Fan H, Huang H, Ma X, et al. Molecular characterization of the flightin gene in the wing-dimorphic planthopper, Nilaparvata lugens, and its evolution in Pancrustacea. Insect Biochem Mol Biol. 2013;43:433-43 pubmed publisher
    ..These results illustrate the functional variations of flightin in insects and other arthropod species and provide clues as to how insects with flight apparatuses evolved from ancient pancrustaceans...
  69. Shi M, Wang Y, Zhu N, Chen X. Four heat shock protein genes of the endoparasitoid wasp, Cotesia vestalis, and their transcriptional profiles in relation to developmental stages and temperature. PLoS ONE. 2013;8:e59721 pubmed publisher
    ..vestalis. Our results suggest that the expression of heat shock proteins reflects to some extent the developmental changes and environmental requirements of insects. ..
  70. Zhu Q, Zhang S, Wang M, Chen J, Zheng Z. Inhibitory effects of selected dietary flavonoids on the formation of total heterocyclic amines and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in roast beef patties and in chemical models. Food Funct. 2016;7:1057-66 pubmed publisher
  71. Wang Y, Xu C, Xu Z, Ji C, Liang J, Wang Y, et al. Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy. Neuron. 2017;95:92-105.e5 pubmed publisher
    ..These results demonstrated that depolarized GABAergic signaling in subicular microcircuit mediates sGS in TLE. This may be of therapeutic interest in understanding the pathological neuronal circuitry underlying sGS. VIDEO ABSTRACT. ..
  72. Jin H, Xiang L, Shao J. Identification and characterization of suppressor of cytokine signaling 1 (SOCS-1) homologues in teleost fish. Immunogenetics. 2007;59:673-86 pubmed publisher
    ..This is the first report of cloning and characterization of SOCS-1 complementary deoxyribonucleic acids and genes in fish...
  73. Li J, Feng M. Intraspecific tolerance of Metarhizium anisopliae conidia to the upper thermal limits of summer with a description of a quantitative assay system. Mycol Res. 2009;113:93-9 pubmed publisher
    ..88). The method developed to assay quantitatively fungal thermotolerance would be useful for screening of fungal candidates for improved pest control in summer. ..
  74. Lu X, Sun D, Chen Z, Chen T, Li L, Xu Z, et al. Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract. J Agric Food Chem. 2010;58:10661-7 pubmed publisher
    ..Moreover, the upper digestive tract plays a key role in the hydrolysis and absorption of flavonoids in CME. ..
  75. Fang L, Wang H, Zhou L, Yu D. FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells. Toxicol Appl Pharmacol. 2011;251:8-15 pubmed publisher
    ..These results may represent a novel mechanism by which rapamycin/cisplatin combination therapy proves to be a potent molecular-targeted strategy for OSCC. ..
  76. Tang W, Guo H, Yang J, Chen B, Wang X. Suppression of tissue inhibitors of metalloproteinases may reverse severe pulmonary arterial hypertension. Cytotherapy. 2011;13:499-502 pubmed publisher
  77. Fan X, Zhou H, Xia Z, Niu H, Luo J. [Effects of Huoxuezhitong recipe on the pathway of mitochondrial apoptosis and the expression of related gene in epidural scar tissue]. Zhongguo Gu Shang. 2010;23:776-9 pubmed
  78. Wu X, Zhu J, Liu H, Lu Z, Zheng M. Expression and location of phospho-Artemis (Serine516) in hair follicles during induced growth of mouse hair. Arch Dermatol Res. 2012;304:319-24 pubmed publisher
    ..Based on the phenomenon that the expression of Artemis (Serine516) in mid-anagen and mature anagen was stronger than that in telogen and catagen, we suggest it may take roles in induced growth of mouse hair. ..
  79. Shou Q, Pan S, Tu J, Jiang J, Ling Y, Cai Y, et al. Modulation effect of Smilax glabra flavonoids on ryanodine receptor mediated intracellular Ca2+ release in cardiomyoblast cells. J Ethnopharmacol. 2013;150:389-92 pubmed publisher
    ..Our results suggest that the protective effects of SGF are mediated via targeting inhibition of RyR mediated intracellular Ca(2+) release. ..
  80. Sheng Y, Xu C, Zeng W. TAB3 defect induces augmented cardioprotection loss from ischemic injury. Cell Biol Int. 2017;41:787-797 pubmed publisher
    ..In summary, our findings indicate that the absence of TAB3 plays a harmful role in ischemic heart disease. ..
  81. Liu T, Angelo J, Lin D, Lenhoff A, Yao S. Characterization of dextran-grafted hydrophobic charge-induction resins: Structural properties, protein adsorption and transport. J Chromatogr A. 2017;1517:44-53 pubmed publisher
  82. Wang Q, Yu H, Zhang L, Ju D, Pan J, Xia D, et al. Adenovirus-mediated intratumoral lymphotactin gene transfer potentiates the antibody-targeted superantigen therapy of cancer. J Mol Med (Berl). 2002;80:585-94 pubmed
  83. Chen W, Wang J, Shao C, Liu S, Yu Y, Wang Q, et al. Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells. Eur J Immunol. 2006;36:1598-607 pubmed
    ..These findings provide a novel strategy to improve the efficacy of exosome-based tumor vaccines. ..
  84. Dong A, Kong M, Ma Z, Qian J, Xu X. Down-regulation of IGF-IR using small, interfering, hairpin RNA (siRNA) inhibits growth of human lung cancer cell line A549 in vitro and in nude mice. Cell Biol Int. 2007;31:500-7 pubmed
    ..Our results support the therapeutic potential of RNAi as a method for gene therapy in treating lung cancer. ..
  85. Tong X, Zheng S, Bader A, Yao H, Wu N, Altmeyer P, et al. Construction of expression vector of hTERT- hIL18 fusion gene and induction of cytotoxic T lymphocyte response against hTERT. Eur J Med Res. 2008;13:7-14 pubmed
    ..DCs transfected with hTERT-IL18 gene were capable of eliciting a stronger hTERT-specific CTL response in vitro. ..
  86. Zhang P, Shu J, Fu C, Zhou Y, Hu Y, Zalucki M, et al. Trade-offs between constitutive and induced resistance in wild crucifers shown by a natural, but not an artificial, elicitor. Oecologia. 2008;157:83-92 pubmed publisher
  87. Zou X, Zhi Y, Chen X, Jin H, Wang L, Jiang Y, et al. Mesenchymal stem cell seeded knitted silk sling for the treatment of stress urinary incontinence. Biomaterials. 2010;31:4872-9 pubmed publisher
    ..And the better ligament-like tissue formation in the tissue engineered sling suggested potential long-term function. ..
  88. Ding L, Xu Y, Zhang W, Deng Y, Si M, Du Y, et al. MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res. 2010;20:784-93 pubmed publisher
    ..Thus, these data suggest that miR-375 may function as a tumor suppressor to regulate gastric cancer cell proliferation potentially by targeting the JAK2 oncogene, implicating a role of miR-375 in the pathogenesis of gastric cancer. ..
  89. Fang S, Wang J, Jiang H, Zhang Y, Xi W, Zhao C, et al. Experimental study on the therapeutic effect of positron emission tomography agent [¹?F]-labeled 2-deoxy-2-fluoro-d-glucose in a colon cancer mouse model. Cancer Biother Radiopharm. 2010;25:733-40 pubmed publisher
    ..05). The study suggests that ¹?F-FDG has a therapeutic effect in colonic cancer animal model, which indicates the potential for the development of positron therapy for colonic cancer and other cancers. ..
  90. Jiang Y, Yang Y, Wang S, Ding Y, Guo Y, Zhang M, et al. Ketogenic diet protects against epileptogenesis as well as neuronal loss in amygdaloid-kindling seizures. Neurosci Lett. 2012;508:22-6 pubmed publisher
    ..In addition, KD also possesses a neuroprotective function during kindling although it changes hippocampal development in early life. ..
  91. Zhang D, Wang L, Chen X, Wang J, Cao H, Huang L. [Determination of ten basic dyes in meat products by ultra fast liquid chromatography-ion trap time of flight mass spectrometry]. Se Pu. 2012;30:770-6 pubmed
    ..39% to 119.18%. Therefore, this method, owing to its simplicity, rapidity and high sensitivity, has a good applicability to the simultaneous determination of dye residues in meat products...
  92. Xu Y, Zhou Y, Lin H, Hu H, Wang Y, Xu G. Toll-like receptor 2 in promoting angiogenesis after acute ischemic injury. Int J Mol Med. 2013;31:555-60 pubmed publisher
    ..TLR2 activation promotes angiogenesis in vivo, which may be associated with the serum of TNF-? levels and IL-6 release. ..