Experts and Doctors on humans in Chengdu, Sichuan, China


Locale: Chengdu, Sichuan, China
Topic: humans

Top Publications

  1. Ling B, Liang S, Xu Y, Zhao X, Tang M, Liu X, et al. Differential proteomic analysis of HeLa cells treated with Honokiol using a quantitative proteomic strategy. Amino Acids. 2008;35:115-22 pubmed
    ..The changed proteins were classified into 9 different categories, which covered a broad variety of cellular functions. In conclusion, HNK performs cytotoxicity to HeLa cells through co-operating of many proteins and different pathways. ..
  2. He Y, Chen Q, Li B. ATM in oral carcinogenesis: association with clinicopathological features. J Cancer Res Clin Oncol. 2008;134:1013-20 pubmed publisher
    ..ATM might be a candidate biomarker for diagnosis and prognosis in OSCC, as well as a possible genetic marker for early-onset OSCC. ..
  3. Liu M. Acupuncture for stroke in China: needing more high-quality evidence. Int J Stroke. 2006;1:34-5 pubmed publisher
  4. Ning T, Yan X, Lu Z, Wang G, Zhang N, Yang J, et al. Gene therapy with the angiogenesis inhibitor endostatin in an orthotopic lung cancer murine model. Hum Gene Ther. 2009;20:103-11 pubmed publisher
  5. Gao F, Huang C, Lin M, Wang Z, Shen J, Zhang H, et al. Frequent inactivation of RUNX3 by promoter hypermethylation and protein mislocalization in oral squamous cell carcinomas. J Cancer Res Clin Oncol. 2009;135:739-47 pubmed publisher
    ..001) were correlated with the differentiation grades in OSCCs. RUNX3 plays an important role in oral carcinogenesis. It may be a useful diagnostic marker and a potential therapeutic target for OSCC. ..
  6. Yao J, Yang Z, Chen T, Li Y, Yang L. Perfusion changes in gastric adenocarcinoma: evaluation with 64-section MDCT. Abdom Imaging. 2010;35:195-202 pubmed publisher
    ..The first-pass perfusion CT with whole tumor acquisition technique is a feasible technique for quantifying tumor vascularity and angiogenesis in gastric adenocarcinoma. ..
  7. Hu Y, Zhao Y, Chen L, Zhu Z, Liu L, Wang Y, et al. Comparative study of different treatments for malignant tracheoesophageal/bronchoesophageal fistulae. Dis Esophagus. 2009;22:526-31 pubmed publisher
    ..With patients' QOL considered, the self-expandable coated stenting should be the first choice of therapy for malignant tracheoesophageal/bronchoesophageal fistula, whereas gastrostomy should be kept from use. ..
  8. Pan X, Li D, Yang L, Wang E, Chen T, Liu Y, et al. No association between vitamin D receptor polymorphisms and coronary artery disease in a Chinese population. DNA Cell Biol. 2009;28:521-5 pubmed publisher
    ..83-1.50; for BsmI: odds ratio = 0.74, 95% confidence interval 0.44-1.23). There was no significant difference in the genotype distribution or the allele frequencies of VDR FokI and BsmI between two groups in a Chinese population. ..
  9. Liu K, Zhang J, Ren J, Wang X, Yang H, Lin P. [Interference of human Na/K-ATPase B1 subunit on proliferation and migration of gastric adenocarcinoma cell line SGC-7901]. Ai Zheng. 2009;28:225-31 pubmed
    ..80+/-0.02)% was significantly enhanced comparing to the shNC-7901 (1.15+/-0.05)% and the shNC-7901 groups (1.25+/-0.02)% (p<0.05). Silencing of ATP1B1 gene can enhance the proliferation and migration capability of SGC-7901 cells. ..

More Information

Publications405 found, 100 shown here

  1. Xu B, Lv B, Feng Y, Xu G, Du J, Welihinda A, et al. O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorg Med Chem Lett. 2009;19:5632-5 pubmed publisher
    ..6'-O-Spiro C-aryl glucosides exhibited potent in vitro hSGLT2 inhibitory activity but 2'-O-spiro C-aryl glucosides showed no in vitro hSGLT2 inhibitory activity at a screening concentration of 1microM. ..
  2. Gong G, Qin Y, Huang W, Zhou S, Wu X, Yang X, et al. Protective effects of diosgenin in the hyperlipidemic rat model and in human vascular endothelial cells against hydrogen peroxide-induced apoptosis. Chem Biol Interact. 2010;184:366-75 pubmed publisher
  3. Desong Liu -, Fang Lu -, Songhui Zhai -, Liu Wei -, Shi Ma -, Xiuying Chen -, et al. Renin-angiotensin system gene polymorphisms in children with Henoch-Schönlein purpura in West China. J Renin Angiotensin Aldosterone Syst. 2010;11:248-55 pubmed publisher
    ..045, p = .026). We suggest that RAS gene polymorphisms (ACE-I/D, M235T or T174M) are significantly associated with susceptibility to HSP, organ involvement, and disease severity, which largely account for individual prognosis. ..
  4. Deng R, Tang B, Liu H, Qu Y, My D. [Risk factors on the occurrence and prognosis of neonatal hyaline membrane disease]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2010;41:688-91 pubmed
    ..To identify risk factors with related to the occurrence and prognosis of neonatal hyaline membrane disease (HMD) and to develop effective measures to prevent and treat the disease...
  5. Li Y, Zheng W, Liu J, Wang J, Yang P, Li M, et al. Expression of osteoclastogenesis inducers in a tissue model of periodontal ligament under compression. J Dent Res. 2011;90:115-20 pubmed publisher
    ..periodontal ligament, PDL; periodontal ligament cells, PDLCs; poly (lactic-co-glycolic acid), PLGA; orthodontic tooth movement, OTM; extracellular matrix, ECM. ..
  6. Gong J, Ren J, Tian F, Jiang R, Tang L, Pang Y. Management of patients with sphincter of Oddi dysfunction based on a new classification. World J Gastroenterol. 2011;17:385-90 pubmed publisher
    ..2%) were under observation. The newly proposed SOD classification system introduced in this study better explains the clinical symptoms of SOD from the anatomical perspective and can guide clinical treatment of this disease. ..
  7. Duan X, Zhong G, Cen S, Huang F, Xiang Z. Plating versus intramedullary pin or conservative treatment for midshaft fracture of clavicle: a meta-analysis of randomized controlled trials. J Shoulder Elbow Surg. 2011;20:1008-15 pubmed publisher
    ..Intramedullary pinning and conservative treatments have also been commonly used. We hypothesized that intramedullary pinning and conservative treatments have the same treatment results compared with plating...
  8. Liu Y, Jiang M, Li C, Yang P, Sun H, Tao D, et al. Human t-complex protein 11 (TCP11), a testis-specific gene product, is a potential determinant of the sperm morphology. Tohoku J Exp Med. 2011;224:111-7 pubmed
    ..Co-immunoprecipitation assays of sperm cell extracts confirmed that TCP11 protein interacted with ODF1. These results suggest that TCP11 may be responsible for the sperm tail morphology and motility. ..
  9. Yang L, Lin C, Wang L, Guo H, Wang X. Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications. Exp Cell Res. 2012;318:2417-26 pubmed publisher
  10. Zheng L, Zhang D, Chen X, Yang L, Wei Y, Zhao X. Antitumor activities of human placenta-derived mesenchymal stem cells expressing endostatin on ovarian cancer. PLoS ONE. 2012;7:e39119 pubmed publisher
    ..These results suggested that hpMSCs are potentially an effective delivery vehicle for therapeutic genes for the treatment of ovarian cancer. ..
  11. Yang Y, Zhang X, Fu Y, Yang H. Leptin and IL-8: two novel cytokines screened out in childhood lead exposure. Toxicol Lett. 2014;227:172-8 pubmed publisher
    ..98(13.64-33.50) pg/mL] (p=0.013). The results defined specific changes in cytokine expressions to lead exposure, which can be used to explore the mechanism of lead toxicity and monitor lead exposure. ..
  12. Zhang D, Li J, Wu H, Cui Y, Bi R, Zhou H, et al. CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease. Neuropsychopharmacology. 2016;41:1034-45 pubmed publisher
    ..These comprehensive analyses suggested that CFH is an important immune factor in AD and affects multiple pathological changes in early life and during disease progress. ..
  13. Jian C, Fan Q, Hu Y, He Y, Li M, Zheng W, et al. Effects of rhBMP-2 gene transfection to periodontal ligament cells on osteogenesis. Biosci Rep. 2017;37: pubmed publisher
    ..The present study demonstrated that rhBMP-2 transfection enhances the osteogenesis of PDL cells and provides a possibility for the application of rhBMP-2 expression products in dental disease treatment. ..
  14. Zhou W, Wei L, Xiao T, Lai C, Peng M, Xu L, et al. Diabetogenic agent alloxan is a proteasome inhibitor. Biochem Biophys Res Commun. 2017;488:400-406 pubmed publisher
    ..These results demonstrate that alloxan is a proteasome inhibitor, which suggests that its specific toxicity toward ?-cell is at least in part through proteasome inhibition. ..
  15. Li Y, Wei X, Zhao Z, Liao Y, He J, Xiong T, et al. Prevalence and Complications of Bicuspid Aortic Valve in Chinese According to Echocardiographic Database. Am J Cardiol. 2017;120:287-291 pubmed publisher
    ..18% episodes per patient-years with mean age of 43.00 ± 5.14 years, respectively. In conclusion, our study demonstrated that the prevalence of BAV and complications in Chinese was similar to that in the western population. ..
  16. Hu J, Wu T, Li H, Zuo Z, Zhao Y, Yang L. The synthesis, structure-toxicity relationship of cisplatin derivatives for the mechanism research of cisplatin-induced nephrotoxicity. Bioorg Med Chem Lett. 2017;27:3591-3594 pubmed publisher
  17. Wang G, Wang L, Xiong Z, Mao B, Li T. Compound salvia pellet, a traditional Chinese medicine, for the treatment of chronic stable angina pectoris compared with nitrates: a meta-analysis. Med Sci Monit. 2006;12:SR1-7 pubmed
    ..To determine the efficacy and safety of CSP for the treatment of stable angina pectoris (SAP), a meta-analysis was undertaken...
  18. Yang Y, Xiao C, A Z, Zhang S, Li X, Zhang S. DAZ1/DAZ2 cluster deletion mediated by gr/gr recombination per se may not be sufficient for spermatogenesis impairment: a study of Chinese normozoospermic men. Asian J Androl. 2006;8:183-7 pubmed
    ..The presence of gr/gr-DAZ1/DAZ2 deletion in five men with normozoospermia suggests that this deletion per se may not be sufficient for spermatogenic impairment in Chinese men. ..
  19. Che G, Chen J, Liu L, Wang Y, Li L, Qin Y, et al. Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981. Neoplasma. 2006;53:530-7 pubmed
  20. Min min H, Ming rong X, Ze yi C, Kai xuan Y, Zhi lin S. Analysis of p53 codon 72 polymorphism and its association with human papillomavirus 16 and 18 E6 in Chinese cervical lesions. Int J Gynecol Cancer. 2006;16:2004-8 pubmed
    ..p53 codon 72 polymorphism has no relation with the FIGO staging and grades of cervical cancer. p53 Arg homozygosity and HR-HPV E6 positive simultaneously can predict the fate of cervical lesions. ..
  21. Chen J, Liu B, Ji N, Zhou J, Bian H, Li C, et al. A novel sialic acid-specific lectin from Phaseolus coccineus seeds with potent antineoplastic and antifungal activities. Phytomedicine. 2009;16:352-60 pubmed publisher
  22. Yu T, Zhou S, Zhang J. Ultrasonic therapy for gynecologic tumors. J Minim Invasive Gynecol. 2008;15:667-72 pubmed publisher
    ..Transvaginal ultrasonic therapy can be applied for a lesion near the cervix. In summary, ultrasonic therapy is a promising treatment modality for gynecologic tumors, and might change clinical practices. ..
  23. Cheng R, Zhou X, Liu Z, Yang H, Gao Q, Hu T. Finite element analysis of the effects of three preparation techniques on stresses within roots having curved canals. Int Endod J. 2009;42:220-6 pubmed publisher
    ..To compare stress distribution within roots having curved canals prepared by three preparation techniques when subjected to occlusal loads and condensation loads as a consequence of different filling techniques...
  24. Lu J, Zhang W, Hao Y, Zhu Y. Defect of cell wall construction may shield oral bacteria's survival in bloodstream and cause infective endocarditis. Med Hypotheses. 2009;73:1055-7 pubmed publisher
    ..As outlined above, we hypothesize that defect of cell wall construction may shield oral bacteria's survival in bloodstream and cause IE. ..
  25. Yang Z, Wang J, Luo R, Maitz M, Jing F, Sun H, et al. The covalent immobilization of heparin to pulsed-plasma polymeric allylamine films on 316L stainless steel and the resulting effects on hemocompatibility. Biomaterials. 2010;31:2072-83 pubmed publisher
    ..The Hep-P-PPAm modified 316L SS shows a promising application for vascular devices...
  26. Li K, Wen T, Li G. Hepatic mucormycosis mimicking hilar cholangiocarcinoma: a case report and literature review. World J Gastroenterol. 2010;16:1039-42 pubmed
    ..Meanwhile, this is the first case of an immunocompetent patient with both adrenal and hepatic mucormycosis who has been treated successfully...
  27. Yang D, Ma S, Tan Y, Li D, Tang B, Zhang X, et al. Increased expression of calpain and elevated activity of calcineurin in the myocardium of patients with congestive heart failure. Int J Mol Med. 2010;26:159-64 pubmed
  28. Lin Y, Li P, Cai L, Zhang B, Tang X, Zhang X, et al. Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population. BMC Med Genet. 2010;11:97 pubmed publisher
    ..We demonstrated that the variants in TCF7L2, CDKAL1, HHEX, and SLC30A8 genes are associated with T2D in a Han Chinese population. ..
  29. Xu B, Feng Y, Lv B, Xu G, Zhang L, Du J, et al. ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorg Med Chem. 2010;18:4422-32 pubmed publisher
    ..Selected compounds were investigated for in vivo efficacy. ..
  30. Zhang Z, Pan J, Li L, Wang Z, Xiao W, Li N. Survey of risk factors contributed to lymphatic metastasis in patients with oral tongue cancer by immunohistochemistry. J Oral Pathol Med. 2011;40:127-34 pubmed publisher
    ..Here, we investigated the expression levels of seven biomarkers in oral squamous cell carcinoma (OSCC) tissues as well as their associations with the clinicopathologic features of OTSCC patients...
  31. Yin Y, Zhang B, Zhou M, Guo J, Lei L, He X, et al. The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese. Neurol India. 2011;59:408-12 pubmed publisher
    ..99 (95% CI, 2.55-7.81, P< 0.001). Our findings suggest that the rs4376531 polymorphism in the ARHGEF10 gene is a risk factor for AS in the Han Chinese population. ..
  32. Tang L, Zhou X, Wang Y, Zhang L, Zheng Q, Huang D. Detection of vertical root fracture using cone beam computed tomography: report of two cases. Dent Traumatol. 2011;27:484-8 pubmed publisher
    ..The clear fracture line can be discerned from the images of CBCT. Thus, CBCT imaging is useful in rapid diagnosis of VRFs and designing of further treatment. ..
  33. Yan L, Liu Q, Zhao J, Bi Y, Yi J. [Study on transportation of Xiaochaihu Tang in Caco-2 cell model]. Zhongguo Zhong Yao Za Zhi. 2011;36:1087-90 pubmed
    ..58 and 1.49, respectively. Baicalin, baicalein and glycyrrhizic acid could not permeate the Caco-2 cell model. The transportation of wogonoside and wogonin in Caco-2 cell model may be a passive transportation. ..
  34. Zheng B, Zhou R, Gong Y, Yang X, Shan Q. Proteasome inhibitor bortezomib overcomes P-gp-mediated multidrug resistance in resistant leukemic cell lines. Int J Lab Hematol. 2012;34:237-47 pubmed publisher
  35. Wang J, Liu Y, Zhang K, Ma B, Zhao Y. [Analysis of the binding domain of hydroxypyruvate isomerase homologues in hypertrophic scar fibroblasts]. Zhonghua Shao Shang Za Zhi. 2012;28:60-4 pubmed
    ..Protein HYI may closely bind with protein P311 by ? helix, which plays an important role in fibroblast-to-myofibroblast transdifferentiation in hypertrophic scar. ..
  36. Zhang H, Zeng J, Wang G, Tu C, Huang F, Pei F. Infectious complications in patients with crush syndrome following the Wenchuan earthquake. Chin J Traumatol. 2013;16:10-5 pubmed
    ..To analyze the results of clinical and bacteriological examinations in patients with crush syndrome who suffered infectious complications after an earthquake in Sichuan, China...
  37. Cao M, Zhou Y, Gao A, Cao J, Gao L, Sheng L, et al. Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth. Biochim Biophys Acta. 2014;1840:2004-13 pubmed publisher
    ..The anti-MM molecular mechanism study of curcusone D will promote combination therapies with different UPP inhibitors against MM and further support the concept of oxidative stress regulating the activity of DUBs. ..
  38. Xue H, Wang C, Li Y, Chen J, Yu L, Liu X, et al. Incidence of type 2 diabetes and number of events attributable to abdominal obesity in China: A cohort study. J Diabetes. 2016;8:190-8 pubmed publisher
    ..Strengthening programs and initiatives for preventing and controlling obesity focusing on lifestyle changes should be a priority in the national strategy to reduce diabetes burden in China. ..
    ..In blood group tests, most of the blood group antigens maintained after lyophilization and rehydration, except that Le(a), Le(b) and JK1 showed high probabilities of falling off during the processes. ..
  40. Wang B, Zhao R, Zhang J, Liu Y, Huang Z, Yu Q, et al. Rigid aromatic linking moiety in cationic lipids for enhanced gene transfection efficiency. Eur J Med Chem. 2017;136:585-595 pubmed publisher
    ..This work demonstrates that a rigid aromatic linkage might distinctly improve the gene transfection abilities of cationic lipids and affords information to construct safe and efficient gene vector towards practical application. ..
  41. Li L, Ding J, Han J, Wu H. A nomogram prediction of postoperative surgical site infections in patients with perihilar cholangiocarcinoma. Medicine (Baltimore). 2017;96:e7198 pubmed publisher
    ..The nomogram can be used to estimate the risk of postoperative SSIs in patients with PHCC. ..
  42. Bian S, Zheng X, Sun H, Chen J, Lu Y, Liu Y, et al. Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signaling in the zebrafish embryo. J Biol Chem. 2017;292:14165-14175 pubmed publisher
  43. Liu Y, Yang T, Yang X, Liu I, Liao W, Lui S, et al. EEG-fMRI study of the interictal epileptic activity in patients with partial epilepsy. J Neurol Sci. 2008;268:117-23 pubmed publisher
    ..Responses to deactivation seem less associated with IEDs. So EEG-fMRI is a useful tool to study the pathophysiological mechanisms of epilepsy and may assist in presurgical evaluation of epilepsy. ..
  44. Hu J, Chen L, Liu L, Chen X, Chen P, Yang G, et al. Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity. Exp Mol Med. 2008;40:617-28 pubmed
    ..Liposomal honokiol can enhance tumor cell radiosensitivity in vitro and in vivo, indicating that radiotherapy combined with liposomal honokiol can lead to greater anti-tumor efficacy. ..
  45. Tong Y, Lin Y, Zhang Y, Yang J, Zhang Y, Liu H, et al. Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis. BMC Med Genet. 2009;10:15 pubmed publisher
    ..Potential gene-gene and gene-environmental interactions by which common variants in the TCF7L2 gene influence the risk of T2MD need further exploration. ..
  46. Gan C, Lin K, An Q, Tang H, Song H, Lui R, et al. Perventricular device closure of muscular ventricular septal defects on beating hearts: initial experience in eight children. J Thorac Cardiovasc Surg. 2009;137:929-33 pubmed publisher
    ..2 days (range, 5-11 days). Perventricular device closure of muscular ventricular septal defects with or without coexisting congenital malformations appeared to be safe and efficacious. The outcomes of short-term follow-up are acceptable. ..
  47. Sun H, Wei L, Liu X, Zeng Y, Lai Y, Yin H. [The role of CXCR1/2 in shear stress-induced endothelial cell migration]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009;26:512-7 pubmed
    ..These results suggest that both CXCR1 and CXCR2 are important factors in mediating the migration of endothelial cells induced by shear stress, and CXCR1 fulfills a more important role. ..
  48. Liao W, Zhang Z, Pan Z, Mantini D, Ding J, Duan X, et al. Altered functional connectivity and small-world in mesial temporal lobe epilepsy. PLoS ONE. 2010;5:e8525 pubmed publisher
    ..We suggest that the mTLE alterations observed in functional connectivity and topological properties may be used to define tentative disease markers. ..
  49. Sun Y, Zang Z, Xu X, Zhang Z, Zhong L, Zan W, et al. The association of SULT1A1 codon 213 polymorphism and breast cancer susceptibility: meta-analysis from 16 studies involving 23,445 subjects. Breast Cancer Res Treat. 2011;125:215-9 pubmed publisher
    ..However, large number of samples and representative hospital-based studies with homogeneous breast cancer patients and well-matched controls are warranted to confirm this finding. ..
  50. Su X, Li G, Liu W, Xie B, Jiang Y. Cytological differential diagnosis among adenocarcinoma, epithelial mesothelioma, and reactive mesothelial cells in serous effusions by immunocytochemistry. Diagn Cytopathol. 2011;39:900-8 pubmed publisher
    ..EMA and Des should be used to differentiate malignant epithelial mesothelioma and reactive mesothelial cells. EMA positive and Des negative favor MM, while Des positive and EMA negative favor RM. ..
  51. Hu Z, Zeng X, Fu P, Luo Z, Tu Y, Liang J, et al. Predictive factors for acute renal failure in crush injuries in the Sichuan earthquake. Injury. 2012;43:613-8 pubmed publisher
    ..The entrapped time under the debris, multiple crush injuries, male gender, infections, and creatine kinase level are predictive factors for ARF in crush injuries. ..
  52. Wang Q, Zhou X, Zheng Q, Wang Y, Tang L, Huang D. Distribution of Porphyromonas gingivalis fimA genotypes in chronic apical periodontitis associated with symptoms. J Endod. 2010;36:1790-5 pubmed publisher
    ..The present study aims to determine the prevalence of P. gingivalis fimA genotypes in apical periodontitis and to investigate the correlation between P. gingivalis fimA genotypes and clinical symptoms...
  53. He C, Yang Z, Chu Z, Dong Z, Shao H, Deng W, et al. Carotid and cerebrovascular disease in symptomatic patients with type 2 diabetes: assessment of prevalence and plaque morphology by dual-source computed tomography angiography. Cardiovasc Diabetol. 2010;9:91 pubmed publisher
    ..A relatively high proportion of plaques were noncalcified, as well as with nonobstructive stenosis. The distribution of plaques was extensive, with the cavernous portion of ICA being the most common site. ..
  54. Liu F, Li B, Wei Y, Yan L, Wen T, Zhao J, et al. XRCC1 genetic polymorphism Arg399Gln and hepatocellular carcinoma risk: a meta-analysis. Liver Int. 2011;31:802-9 pubmed publisher
    ..No publication bias was found in the present study. No association is found between the XRCC1 polymorphism Arg399Gln and the risk of HCC. ..
  55. Duan X, He S, Liao W, Liang D, Qiu L, Wei L, et al. Reduced caudate volume and enhanced striatal-DMN integration in chess experts. Neuroimage. 2012;60:1280-6 pubmed publisher
  56. Shi S, Zhou B, Wang Y, Chen Y, Zhang K, Wang K, et al. Genetic variation in RTN4 3'-UTR and susceptibility to cervical squamous cell carcinoma. DNA Cell Biol. 2012;31:1088-94 pubmed publisher
    ..It is necessary to confirm these findings in ethnically different populations and with a larger sample. ..
  57. Zhu J, Li X, Wang Y, Mu D, Dai L, Zhou G, et al. Prevalence of neural tube defect pregnancies in China and the impact of gestational age of the births from 2006 to 2008: a hospital-based study. J Matern Fetal Neonatal Med. 2012;25:1730-4 pubmed publisher
  58. Xiao G, Guo Q, Shu M, Xie X, Deng J, Zhu Y, et al. Safety profile and outcome of mild therapeutic hypothermia in patients following cardiac arrest: systematic review and meta-analysis. Emerg Med J. 2013;30:91-100 pubmed publisher
    ..But awareness of these adverse events should be kept in mind in clinical practice. ..
  59. Ye H, Fu A, Wu W, Li Y, Wang G, Tang M, et al. Cytotoxic and apoptotic effects of constituents from Millettia pachycarpa Benth. Fitoterapia. 2012;83:1402-8 pubmed publisher
    ..It was found to be the most potent apoptotic inducer of the compounds isolated from M. pachycarpa Benth...
  60. Cai L, Wang X, Wang W, Qiu N, Wen J, Duan X, et al. Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo. Int J Nanomedicine. 2012;7:4499-510 pubmed publisher
    ..The truncated fibroblast growth factor fragment-conjugated PEGylated liposome has promising potential as a long-circulating and tumor-targeting carrier system. ..
  61. Lei J, Yan L. Comparison between living donor liver transplantation recipients who met the Milan and UCSF criteria after successful downstaging therapies. J Gastrointest Surg. 2012;16:2120-5 pubmed publisher
    ..The pathology findings were not different between the two groups. Recipients who meet the Milan or UCSF criteria after accepting successful preoperative downstaging therapy in LDLT can achieve the same result. ..
  62. Cheng K, Zhao F, Gao F, Dong H, Men H, Chen Y, et al. Factors potentially associated with chemotherapy-induced anemia in patients with solid cancers. Asian Pac J Cancer Prev. 2012;13:5057-61 pubmed
    ..Our analysis firstly described some risk factors, such as decrease of platelets or WBCs, severity of leucopenia or thrombocytopenia, associated with the occurrence and severity of CIA. ..
  63. Zhang K, Zhou B, Shi S, Song Y, Zhang L. Variations in the PDCD6 gene are associated with increased uterine leiomyoma risk in the Chinese. Genet Test Mol Biomarkers. 2013;17:524-8 pubmed publisher
    ..The present study provided evidence that rs4957014 and rs3756712 are associated with UL risk, the results indicated that genetic polymorphisms in PDCD6 may contribute to the development of UL. ..
  64. Zhou C, Grottkau B, Zou S. Regulators of Stem Cells Proliferation in Tissue Regeneration. Curr Stem Cell Res Ther. 2016;11:177-87 pubmed
    ..We also emphasize the significance of stem cells proliferation in cell research, as well as rapid propagation of adult stem cells for regenerative medicine. ..
  65. Wang Z, Sun L, Wu Y, Xia Q. Extended duration versus standard duration of peginterferon alfa-2a in treatment of chronic hepatitis B: A systematic review and meta-analysis. Clin Res Hepatol Gastroenterol. 2016;40:195-202 pubmed publisher
    ..01]. Therefore, extended treatment with PEG-IFNa-2a beyond 48 weeks may be a promising strategy to achieve higher rates of sustained HBV-DNA inhibition, HBeAg seroconversion and HBsAg clearance off-therapy for patients with CHB. ..
  66. Yin Y, Hua H, Li M, Liu S, Kong Q, Shao T, et al. mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR. Cell Res. 2016;26:46-65 pubmed publisher
    ..Finally, overexpression of rictor promotes IGF-induced cell proliferation. Our work identifies mTOR as a dual-specificity kinase and clarifies how mTORC2 promotes IGF-IR/InsR activation. ..
  67. Zhao Z, Ji L, Zheng L, Yang L, Yuan H, Chen L, et al. Effectiveness of clinical alternatives to nerve conduction studies for screening for diabetic distal symmetrical polyneuropathy: A multi-center study. Diabetes Res Clin Pract. 2016;115:150-6 pubmed publisher
    ..Combined AR+T+V assessment is a valuable tool for screening diabetic patients for DSPN, potentially decreasing costs to local primary care facilities and making care more available to underserved populations. ..
  68. Ye C, Li Z, Fu Y, Lan Y, Zhu W, Zhou D, et al. SCM: a practical tool to implement hospital-based syndromic surveillance. BMC Res Notes. 2016;9:315 pubmed publisher
  69. Fang Z, Wang T, Li H, Zhang G, Wu X, Yang L, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017;27:3201-3204 pubmed publisher
    ..Among them, compound 10r is the most potent one with an IC50 value of 0.41±0.03?M against KDM4D. Overall, compound 10r could be taken as a good lead compound for further studies. ..
  70. Mi Y, He M, Liu B. [MiR-133b Affect the Proliferation and Drug Sensitivity in A549 Lung Cancer Stem Cells by Targeting PKM2]. Zhongguo Fei Ai Za Zhi. 2017;20:376-381 pubmed publisher
    ..05?????miR-133b???????????????PKM2?????P<0.05??DDP??12 h?miR-133b mimics????????????????P<0.05??miR-133b mimics+DDP?PKM2?????????????miR-133b inhibitor??P<0.05???? ???miR-133b??????PKM2???????????????????????????DDP?????. ..
  71. Long S, Tian Y, Zhang R, Yang L, Xu Y, Jia L, et al. Relationship between plasma HDL subclasses distribution and lipoprotein lipase gene HindIII polymorphism in hyperlipidemia. Clin Chim Acta. 2006;366:316-21 pubmed
    ..The particle size of HDL shifted toward smaller, which, in turn, indicated that RCT might be weakened and HDL maturation might be abnormal in hyperlipidemic subjects with 495TT genotype. ..
  72. Wang B, Rao L, Zhang L, Zhou B, Wang Y, Chen X. [Correlation between desmin gene, platelet-activating factor acetylhydrolase gene and dilated cardiomyopathy]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2006;37:391-4 pubmed
    ..05). Neither the mutation of Ile451Met in gene encoding for Desmin exon 8 nor the mutation frequency of PAF-AH gene (G994-->T) has correlation with the DCM. ..
  73. Zhou B, Zhang Q, Tian L, Xiao J, Stefan H, Zhou D. Effects of levetiracetam as an add-on therapy on cognitive function and quality of life in patients with refractory partial seizures. Epilepsy Behav. 2008;12:305-10 pubmed
    ..Some of these improvements may be maintained during long-term treatment. ..
  74. Yang Y, Ma M, Li L, Zhang W, Xiao C, Li S, et al. Evidence for the association of Y-chromosome haplogroups with susceptibility to spermatogenic failure in a Chinese Han population. J Med Genet. 2008;45:210-5 pubmed
    ..Our findings emphasise the necessity of more extensive study on Y-chromosome variations for better understanding of spermatogenesis and its pathology. ..
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    ..pylori infection and ethnicity/country. More well-designed studies based on larger population are needed to confirm our results and further evaluate the association between IL-8 -251 A/T gene polymorphism and gastric cancer. ..
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    ..These results justify larger, more rigorous studies to confirm such a diagnostic role. ..