Experts and Doctors on histone deacetylases in Jinan, Shandong Sheng, China
Locale: Jinan, Shandong Sheng, China
Topic: histone deacetylases
Zhang S, Li J, Jiang Y, Xu Y, Qin C. Programmed cell death 4 (PDCD4) suppresses metastastic potential of human hepatocellular carcinoma cells. J Exp Clin Cancer Res. 2009;28:71 pubmed publisher
..PDCD4 expression is inversely correlated to the metastatic potential of HCC cells. PDCD4 can effectively suppress the metastatic potential of HCC cells. ..
Li S, Tian H, Yue W, Li L, Li W, Chen Z, et al
. Overexpression of metastasis-associated protein 1 is significantly correlated with tumor angiogenesis and poor survival in patients with early-stage non-small cell lung cancer. Ann Surg Oncol. 2011;18:2048-56 pubmed publisher
Jing X, Sui W, Wang S, Xu X, Yuan R, Chen X, et al
. HDAC7 Ubiquitination by the E3 Ligase CBX4 Is Involved in Contextual Fear Conditioning Memory Formation. J Neurosci. 2017;37:3848-3863 pubmed publisher
..All of these proteins, including HDAC7, CBX4, and Nur77, could be potential therapeutic targets for preventing memory deficits in aging and neurological diseases. ..
Yan B, Liu Y, Bai H, Chen M, Xie S, Li D, et al
. HDAC6 regulates IL-17 expression in T lymphocytes: implications for HDAC6-targeted therapies. Theranostics. 2017;7:1002-1009 pubmed publisher
..These findings also have important implications for the clinical investigation of HDAC6-targeted therapies. ..
Rong Y, Zhang M, Zhang L, Wang X, Shen Y. JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter. FEBS Lett. 2010;584:852-8 pubmed publisher
..This study provides novel insight into TM down-regulation by stress signaling pathways. ..
Li S, Tian H, Yue W, Li L, Gao C, Li W, et al
. Metastasis-associated protein 1 nuclear expression is closely associated with tumor progression and angiogenesis in patients with esophageal squamous cell cancer. World J Surg. 2012;36:623-31 pubmed publisher
Li S, Tian H, Yue W, Li L, Gao C, Si L, et al
. Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line. Acta Biochim Biophys Sin (Shanghai). 2013;45:115-22 pubmed publisher
He M, Zhang B, Wei X, Wang Z, Fan B, Du P, et al
. HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury. J Cell Mol Med. 2013;17:531-42 pubmed publisher