Experts and Doctors on atherosclerosis in Changchun, Jilin Sheng, China
Locale: Changchun, Jilin Sheng, China
Yang P, Li Y, Li J, Qin L, LI X. Up-regulating PPAR-? expression and NO concentration, and down-regulating PAI-1 concentration in a rabbit atherosclerotic model: the possible antiatherogenic and antithrombotic effects of atorvastatin. Int J Cardiol. 2010;139:213-7 pubmed publisher
Cao H, Qin L, Huang K. [Effects of Tongxinluo on MMP-3, 9 and PPARgamma expressions in atherosclerotic rabbits]. Nan Fang Yi Ke Da Xue Xue Bao. 2009;29:1887-9 pubmed
..01). Tongxinluo can inhibit the expression of MMP-3 and 9 and increase the expression of PPARgamma, which might be the mechanism of its anti-atherosclerotic effect. ..
Li Y, Yang C, Zhang L, Yang P. MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis. Cell Mol Biol Lett. 2017;22:3 pubmed publisher
..Our study suggests a novel role for miR-210 in the progression of atherosclerosis through the regulation of endothelial apoptosis. This indicates that miR-210 might have potential in treatment of atherosclerosis. ..
Xu K, Liu P, Zhao Y. Upregulation of microRNA-876 Induces Endothelial Cell Apoptosis by Suppressing Bcl-Xl in Development of Atherosclerosis. Cell Physiol Biochem. 2017;42:1540-1549 pubmed publisher
..AS-associated endothelial cell apoptosis may partially result from downregulation of Bcl-Xl, through upregulation of miR-876 that binds and suppresses translation of Bcl-Xl mRNA. ..