Experts and Doctors on animals in Nanjing, Jiangsu, China


Locale: Nanjing, Jiangsu, China
Topic: animals

Top Publications

  1. Guo S, Cai B, Li D, Wang T. [Study on process of removing impurity from water-extraction of gutianquan-capsule]. Zhongguo Zhong Yao Za Zhi. 2003;28:130-2 pubmed
    ..To study the result of removing impurity from water-extraction of Gutianquan-capsule with macro-reticular absorbing resin, chitosans clarification, water-extraction and alcohol-precipitation methods...
  2. Hang C, Shi J, Sun B, Li J. Apoptosis and functional changes of dipeptide transporter (PepT1) in the rat small intestine after traumatic brain injury. J Surg Res. 2007;137:53-60 pubmed
    ..Up-regulation of PepT1 may adaptively improve absorption of di- and tripeptides, independent of changes in the mucosal surface area. ..
  3. Yao Y, Yin H, Shen B, Chao L, Chao J. Tissue kallikrein infusion prevents cardiomyocyte apoptosis, inflammation and ventricular remodeling after myocardial infarction. Regul Pept. 2007;140:12-20 pubmed
    ..These results indicate that kallikrein through kinin B2 receptor activation prevents apoptosis, inflammation and ventricular remodeling by increased nitric oxide formation and suppression of oxidative stress-mediated signaling pathways. ..
  4. Yang H, Liu H, Liu X, Zhang D, Liu Y, Liu X, et al. Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro. Neurosci Lett. 2008;434:299-303 pubmed publisher
    ..The results verified the hypothesis that long-term exposure to the four antiepileptic drugs can induce P-gp function and level in rBMECs. ..
  5. Gan L, Gan Y, Zhu C, Zhang X, Zhu J. Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results. Int J Pharm. 2009;365:143-9 pubmed publisher
    ..This CsA microemulsion in situ electrolyte-triggered gelling system might provide an alternative approach to deliver prolonged precorneal residence time of CsA for preventing cornea allograft rejection. ..
  6. Sun Y, Cai T, Zhou X, Xu Q. Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis. Int Immunopharmacol. 2009;9:978-83 pubmed publisher
    ..This may herald a novel approach for further studies of saikosaponin a as a candidate for the treatment of inflammatory and autoimmune diseases. ..
  7. Guo Y, Xu J, Li N, Gao F, Huang P. RegIV potentiates colorectal carcinoma cell migration and invasion via its CRD domain. Cancer Genet Cytogenet. 2010;199:38-44 pubmed publisher
    ..00 +/- 3.00, 31.53 +/- 2.72, 30.3 +/- 2.07, and 32.16 +/- 2.30 cells per field, respectively. RegIV enhances LoVo cell migration and invasion, and its CRD domain is critical for these effects. ..
  8. Li D, Hu Y, Shen X, Dai X, Han X. Combined effects of two environmental endocrine disruptors nonyl phenol and di-n-butyl phthalate on rat Sertoli cells in vitro. Reprod Toxicol. 2010;30:438-45 pubmed publisher
    ..According to the above phenomena, we inferred that the combined effect of the two substances on Sertoli cell toxicity had an additive effect, and the induction of apoptosis may play an important role. ..
  9. Li Q, Zhang Q, Wang C, Tang C, Zhang Y, Jiang S, et al. Influence of alemtuzumab on the intestinal Paneth cells and microflora in macaques. Clin Immunol. 2010;136:375-86 pubmed publisher
    ..These findings indicated the associations between changes of Paneth cell function and gut microflora and supported the important role of Paneth cells to barrier impairment with the use of alemtuzumab in organ transplantation...

More Information

Publications1269 found, 100 shown here

  1. Gu P, Fan X, Jiang C, Xu H, Yu J, Tang Y. Effect of San'ao Decoction on the airway inflammation and hyperresponsiveness in a murine model of lipopolysaccharide-enhanced asthma. Chin J Integr Med. 2011;17:537-41 pubmed publisher
    ..SAD has a good therapeutic effect on airway hyperresponsiveness in the LPS-enhanced asthma model, but its definite influence on airway inflammation is not remarkable. ..
  2. Dai X, Ge J, Wang X, Qian X, Zhang C, Li X. OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion. Oncol Rep. 2013;29:155-60 pubmed publisher
    ..These results indicate that OCT4 may contribute to CRC cell metastasis through EMT and serves as a promising biomarker for identifying CRC patients at high risk for liver metastases. ..
  3. Zhao D, Chen D, Ge C, Gotoh T, Hong X. Multiple infections with Cardinium and two strains of Wolbachia in the spider mite Tetranychus phaselus Ehara: revealing new forces driving the spread of Wolbachia. PLoS ONE. 2013;8:e54964 pubmed publisher
    ..As a result, the uninfected population is attenuated by the multiple-infected males. Thus, we infer that the host age effects of multiple infection may represent sufficient forces driving the spread of wOri through the host population. ..
  4. Shen H, Liao K, Zhang W, Wu H, Shen B, Xu Z. Differential expression of peroxiredoxin 6, annexin A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1 in testis of rat fetuses after maternal exposure to di-n-butyl phthalate. Reprod Toxicol. 2013;39:76-84 pubmed publisher
  5. Yao W, Peng Y, Du M, Luo J, Zong L. Preventative vaccine-loaded mannosylated chitosan nanoparticles intended for nasal mucosal delivery enhance immune responses and potent tumor immunity. Mol Pharm. 2013;10:2904-14 pubmed publisher
    ..05). Cell binding and cellular uptake results indicated that MCS/pGRP nanoparticles bound with C-type lectin receptors on macrophages. MCS was an efficient targeting gene delivery carrier and could be used in antitumor immunotherapy. ..
  6. Xue han Z, Qing Y, Ya dong L, Bin L, Renata I, Kong wang H. Development of a LAMP assay for rapid detection of different intimin variants of attaching and effacing microbial pathogens. J Med Microbiol. 2013;62:1665-72 pubmed publisher
    ..coli. The eae-LAMP assay has great potential for wider applications, not only in the laboratory but also in the field setting, as it does not require specialized equipment. ..
  7. Lin J, Wu H, Shi H, Pan W, Yu H, Zhu J. Combined inhibition of epidermal growth factor receptor and cyclooxygenase-2 leads to greater anti-tumor activity of docetaxel in advanced prostate cancer. PLoS ONE. 2013;8:e76169 pubmed publisher
    ..Based on previous preclinical research, we conclude that simultaneously blocking EGFR and COX-2 by gefitinib and NS-398 sensitizes advanced PCa cells to docetaxel-induced cytotoxicity. ..
  8. Shi W, Gu J, Li M, Yan L, He X. The predictors of endoleaks after endovascular repair of experimentally produced fusiform carotid aneurysm in canine. Minim Invasive Ther Allied Technol. 2016;25:99-106 pubmed publisher
    ..No parameters were identified to be independent predictors of late endoleaks. Treating carotid FAs with Willis covered stents is technically feasible. Most endoleaks heal spontaneously and significantly correlate with anchoring length. ..
  9. Deng Y, Zhang Y, Lu Y, Zhao Y, Ren H. Hepatotoxicity and nephrotoxicity induced by the chlorpyrifos and chlorpyrifos-methyl metabolite, 3,5,6-trichloro-2-pyridinol, in orally exposed mice. Sci Total Environ. 2016;544:507-14 pubmed publisher
    ..In addition, metabolic disturbances due to TCP exposure were also observed based on altered metabolites. As far as we know, these results are the first to show the metabolomic toxicity of TCP, which warrants further research. ..
  10. Xin M, Zhang L, Jin Q, Tang F, Wen J, Gu L, et al. Discovery of novel 4-(2-pyrimidinylamino)benzamide derivatives as highly potent and orally available hedgehog signaling pathway inhibitors. Eur J Med Chem. 2016;110:115-25 pubmed publisher
  11. Wang H, Feng Z, Wu Y, Wei Y, Gan Y, Hua L, et al. The effects of Mycoplasma hyopneumoniae on porcine circovirus type 2 replication in vitro PK-15 cells. Res Vet Sci. 2016;105:56-61 pubmed publisher
    ..These results offer the evidences to better understand the complex clinical syndromes in Mhp/PCV2 co-infection cases, and the occurrence of PMWS. ..
  12. Huang J, Sun R, Feng S, He J, Fei F, Gao H, et al. Sensitive analysis and pharmacokinetic study of epalrestat in C57BL/6J mice. J Chromatogr B Analyt Technol Biomed Life Sci. 2017;1055-1056:98-103 pubmed publisher
    ..Multi-dose of epalrestat significantly increased MRT and apparent volume of distribution (Vd) relative to those of a single-dose. ..
  13. He L, Fan F, Hou X, Gao C, Meng L, Meng S, et al. Resveratrol suppresses pulmonary tumor metastasis by inhibiting platelet-mediated angiogenic responses. J Surg Res. 2017;217:113-122 pubmed publisher
    ..RSV is a potential therapeutic drug for the prevention of tumor metastasis by interrupting the platelet-tumor cell amplification loop. ..
  14. Zhang Y, Hou Y, Wang X, Ping J, Ma Z, Suo C, et al. The effects of kisspeptin-10 on serum metabolism and myocardium in rats. PLoS ONE. 2017;12:e0179164 pubmed publisher
    ..Our work determined the profound effects of kisspeptin-10 on the heart, which could further lead to the development of therapeutics related to kisspeptin-10, including antagonists and analogs. ..
  15. Yang J, Hu L, Liu X, Zhou F, Ding J, Hu G. Effects of iptakalim on extracellular glutamate and dopamine levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study. Life Sci. 2006;78:1940-4 pubmed
  16. Hao H, Wang G, Cui N, Li J, Xie L, Ding Z. Identification of a novel intestinal first pass metabolic pathway: NQO1 mediated quinone reduction and subsequent glucuronidation. Curr Drug Metab. 2007;8:137-49 pubmed
    ..This study should be helpful for the general understanding of quinones absorption and intestinal first pass metabolism. ..
  17. Jiang W, Jiang P, Li Y, Wang X, Du Y. Analysis of immunogenicity of minor envelope protein GP3 of porcine reproductive and respiratory syndrome virus in mice. Virus Genes. 2007;35:695-704 pubmed
    ..It indicated that the first 64aa fragment of GP3 might affect the conformation of the antigen structures of GP3 protein. GP3 protein should be one of candidate molecules for developing a new safer effective vaccine. ..
  18. Jin G, Ma D, Wu N, Marikar F, Jin S, Jiang W, et al. Combination of human plasminogen kringle 5 with ionizing radiation significantly enhances the efficacy of antitumor effect. Int J Cancer. 2007;121:2539-46 pubmed
    ..The results suggest that rhK5 significantly enhances the antitumor activity of RT and could be a potent adjuvant therapeutic approach to improve the efficacy of radiotherapy for lung cancer. ..
  19. Feng Y, Zhang Q, Dai D, Ying H, Dai Y. Strontium fructose 1,6-diphosphate rescues adenine-induced male hypogonadism and upregulates the testicular endothelin-1 system. Clin Exp Pharmacol Physiol. 2007;34:1131-7 pubmed
    ..These abnormalities were significantly restored by FDP-Sr in a dose-dependent manner. These data indicate the possibility of using FDP-Sr to treat male hypogonadism. ..
  20. Lv H, Wang G, Wu X, Xie L, Huang C, Li H, et al. Transport characteristics of ginkgolide B by Caco-2 cells and examination of ginkgolide B oral absorption potential using rat in situ intestinal loop method. Int J Pharm. 2008;351:31-5 pubmed
    ..The results indicate that the intestinal absorption of ginkgolide B in the upper intestine was significantly higher than that in the lower intestine. ..
  21. Jiang B, Sun L, Hao S, Li X, Hou Y. Estrogen distinctively modulates spleen DC from (NZB x NZW) F1 female mice in various disease development stages. Cell Immunol. 2007;248:95-102 pubmed
    ..The changes of DCs from various age old mice were different even contrast. So E2 participates in SLE through modulating DCs by binding ER alpha. The effects of E2 on DCs from mice in various disease progression stages were different. ..
  22. Pan Y, Chen C, Shen Y, Zhu C, Wang G, Wang X, et al. Curcumin alleviates dystrophic muscle pathology in mdx mice. Mol Cells. 2008;25:531-7 pubmed
    ..Since curcumin is a non-toxic compound derived from plants, we propose that it may be useful for DMD therapy. ..
  23. Zhu Q, Gu X, Yang J, Wang J, Tang B, Wu H. Purification and characterization of biologically active recombinant human Eppin expressed in Escherichia coli. Chin Med J (Engl). 2008;121:620-4 pubmed
    ..The purified His6-Eppin protein has biological activity, which might be a candidate for clinical diagnosis of infertility and development of male immuno-contraceptive agents. ..
  24. Chen Y, Liu C, Xu K, Mao X, Lu Y, Fang L, et al. Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes. Am J Nephrol. 2008;28:1014-22 pubmed publisher
    ..This novel mechanism of TUDCA action suggests new intervention methods for AGEs-induced apoptosis of mouse podocytes in diabetic nephropathy. ..
  25. Qi Q, Peng J, Liu W, You Q, Yang Y, Lu N, et al. Toxicological studies of wogonin in experimental animals. Phytother Res. 2009;23:417-22 pubmed publisher
    ..27-295.26 mg/kg. A long period of treatment with a high dose of wogonin (120 mg/kg) could induce heart injury in rats. These results provide a foundation for the further clinical investigation of this promising anticancer agent. ..
  26. Liu Y, Zha B, Zhang H, Zhu X, Li Y, Zhu J, et al. Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model. J Exp Clin Cancer Res. 2009;28:107 pubmed publisher
  27. Cong R, Sun Q, Yang L, Gu H, Zeng Y, Wang B. Effect of Genistein on vasculogenic mimicry formation by human uveal melanoma cells. J Exp Clin Cancer Res. 2009;28:124 pubmed publisher
    ..05). Genistein inhibits VM formation of uveal melanoma cells in vivo and in vitro. One possible underlying molecular mechanism by which Genistein could inhibit VM formation of uveal melanoma is related to down-regulation of VE-cadherin. ..
  28. Xue C, Guo J, Qian D, Duan J, Shang E, Shu Y, et al. Identification of the potential active components of Abelmoschus manihot in rat blood and kidney tissue by microdialysis combined with ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879:317-25 pubmed publisher
    ..The developed method was simple and reliable, and could be adopted to rapidly screen and identify potential active components contributing to pharmacological effects of TCM and to better clarify its action mechanism...
  29. Kaleri H, Xu S, Lin H. Generation of transgenic chicks using an oviduct-specific expression system. Genet Mol Res. 2011;10:3046-55 pubmed publisher
    ..This character is inherited and can be reproduced with a need for repeated transfection. ..
  30. Huang M, Qian Y, Guan T, Huang L, Tang X, Li Y. Different neuroprotective responses of Ginkgolide B and bilobalide, the two Ginkgo components, in ischemic rats with hyperglycemia. Eur J Pharmacol. 2012;677:71-6 pubmed publisher
    ..These results suggested that CBF plays crucial roles during early stage of reperfusion in the presence of hyperglycemia. Administration of compound that improves CBF may have little effect in hyperglycemic stroke. ..
  31. Zhao Y, Wang Z, Dai J, Chen L, Huang Y, Zhan Z. Beneficial effects of benzodiazepine diazepam on chronic stress-induced impairment of hippocampal structural plasticity and depression-like behavior in mice. Behav Brain Res. 2012;228:339-50 pubmed publisher
    ..Short-term diazepam treatment enhances hippocampal structural plasticity and is beneficial to recovery following chronic stress. ..
  32. Liao S, Shang J, Tian X, Fan X, Shi X, Pei S, et al. Up-regulation of melanin synthesis by the antidepressant fluoxetine. Exp Dermatol. 2012;21:635-7 pubmed publisher
    ..These results suggest that fluoxetine may hold a significant therapeutic potential for treating skin hypopigmentation disorders, and SR1A may serve as a novel target in modulating melanogenesis...
  33. Ju Q, Qu M, Wang Y, Jiang X, Li X, Dong S, et al. Molecular and biochemical characterization of two odorant-binding proteins from dark black chafer, Holotrichia parallela. Genome. 2012;55:537-46 pubmed publisher
    ..This discovery should accelerate research on chemical communications of this pest, which could potentially lead to the improvement of control measures based on lures and traps. ..
  34. Chen H, Zhang X, Dai S, Ma Y, Cui S, Achilefu S, et al. Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-therapy. Theranostics. 2013;3:633-49 pubmed publisher
    ..These results indicate that the multifunctional nanoconstruct is a promising combined therapeutic agent for tumor-targeting treatment, with the potential to enhance the anti-cancer treatment outcomes. ..
  35. Wang J, Wang J, Xu C, Liu R, Chen Y. Molecular mechanism of catalase activity change under sodium dodecyl sulfate-induced oxidative stress in the mouse primary hepatocytes. J Hazard Mater. 2016;307:173-83 pubmed publisher
    ..When the sites in the interface is saturated, SDS interacts with VAL 73, HIS 74, ASN 147 and PHE 152, the key residues of the enzyme activity, and leads to the decrease of CAT activity. ..
  36. Jiang G, Zhang L, Zhu Q, Bai D, Zhang C, Wang X. CD146 promotes metastasis and predicts poor prognosis of hepatocellular carcinoma. J Exp Clin Cancer Res. 2016;35:38 pubmed publisher
    ..CD146 induced EMT, and IL-8 upregulation and STAT1 downregulation may be the potential underlying mechanism. The exact mechanism still needs further investigation. ..
  37. Zhang X, Qian Z, Zhu H, Tang S, Wu D, Zhang M, et al. HSP90 gene expression induced by aspirin is associated with damage remission in a chicken myocardial cell culture exposed to heat stress. Br Poult Sci. 2016;57:462-73 pubmed publisher
  38. Wang K, Liu X, Xiao H, Wang H, Zhang Y. The correlation between inflammatory injury induced by LPS and RAS in EpH4-Ev cells. Int Immunopharmacol. 2017;46:23-30 pubmed publisher
    ..These results suggest that a valid inflammatory injury was induced after the cells were treated by high concentration of LPS for 9h. Meanwhile, the ACE/AngII/AT1R axis was activated and the ACE2/Ang1-7/MasR axis was depressed. ..
  39. Feng X, Yu W, Li X, Zhou F, Zhang W, Shen Q, et al. Apigenin, a modulator of PPAR?, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation. Biochem Pharmacol. 2017;136:136-149 pubmed publisher
    ..Therefore, our results indicate that Api ameliorates NAFLD by a novel regulating mode of Nrf2 and PPAR? in inhibiting lipid metabolism and oxidative stress abnormity. ..
  40. Zhu F, Si J, Wang L, Wang D, Chen P. [Effect of mica granule on the expression of gene-protein associated with cancer in gastric mucosa tissue of chronic atrophic gastritis rats]. Zhongguo Zhong Yao Za Zhi. 2006;31:312-6 pubmed
    ..The treatment and reversion action of mica on chronic atrophic gastritis is probably related with the regulative effect on the expression of gene associated with cancer. ..
  41. Gao Z, Xia Y, Yao X, Dai Y, Wang Q. A new triterpenoid saponin from Gleditisia sinensis and structure-activity relationships of inhibitory effects on lipopolysaccharide-induced nitric oxide production. Nat Prod Res. 2008;22:320-32 pubmed publisher
    ..Structure-activity relationships of the isolated saponins that affected nitric oxide production from cultured mouse macrophages (RAW 264.7 cell lines) induced by lipopolysaccharide were discussed...
  42. Sun Y, Cai T, Shen Y, Zhou X, Chen T, Xu Q. Si-Ni-San, a traditional Chinese prescription, and its active ingredient glycyrrhizin ameliorate experimental colitis through regulating cytokine balance. Int Immunopharmacol. 2009;9:1437-43 pubmed publisher
    ..In conclusion, Si-Ni-San and glycyrrhizin significantly ameliorated TNBS-induced colitis in mice through regulating pro- and anti-inflammatory cytokine production. ..
  43. Li H, Luo Y, Song R, Li Z, Yan T, Zhu H. Design, synthesis, and immunosuppressive activity of new deoxybenzoin derivatives. ChemMedChem. 2010;5:1117-22 pubmed publisher
    ..In addition, the mechanism of apoptosis was detected by western blot analysis. ..
  44. Lee P, Gao W, Zhang X. Performance of single-scattering model versus multiple-scattering model in the determination of optical properties of biological tissue with optical coherence tomography. Appl Opt. 2010;49:3538-44 pubmed publisher
    ..Finally, the scattering properties of in vitro rat liver and in vivo human skin are determined. The results are useful for quantitatively characterizing tissue scattering in biomedical research and clinical diagnosis. ..
  45. Zhao Q, Wang J, Zou M, Hu R, Zhao L, Qiang L, et al. Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. Toxicol Lett. 2010;197:201-10 pubmed publisher
    ..The anti-gastric cancer effect of two-drug combination was much stronger than that of WOG or 5-FU alone. These results may be relevant to design new clinical therapeutic strategies against gastric cancer in future. ..
  46. Liu S, Liu N, He P, Li Z, Dong S, Mu L. Molecular characterization, expression patterns, and ligand-binding properties of two odorant-binding protein genes from Orthaga achatina (Butler) (Lepidoptera: Pyralidae). Arch Insect Biochem Physiol. 2012;80:123-39 pubmed publisher
    ..Additionally, plant volatiles farnesol and farnesene showed high binding with both OachGOBP2 and OachPBP1, suggesting that these volatile chemicals have regulatory functions in the behavior of O. achatina. ..
  47. Jiang T, Gao L, Zhu X, Yu J, Shi J, Tan M, et al. Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats. Pharmacol Res. 2013;71:61-8 pubmed publisher
    ..These findings suggest that treatment with Ang-(1-7) may be useful to prevent hypertension-induced excessive autophagic activation in brain. ..
  48. Yang P, Wang Z, Zhan Y, Wang T, Zhou M, Xia L, et al. Endogenous A1 adenosine receptor protects mice from acute ethanol-induced hepatotoxicity. Toxicology. 2013;309:100-6 pubmed publisher
    ..In conclusion, these results indicated that endogenous A1AR activation protects mice against acute ethanol-induced liver injury by reducing oxidative stress and decreasing lipid accumulation. ..
  49. Zhao X, Hu Y, Wang D, Liu J, Guo L. The comparison of immune-enhancing activity of sulfated polysaccharidses from Tremella and Condonpsis pilosula. Carbohydr Polym. 2013;98:438-43 pubmed publisher
    ..These indicated that sulfation modification could improve the immune-enhancing activity of TPS and CPPS, sTPS70c possessed the strongest activity and would be expected as a component of new-type immunopotentiator. ..
  50. Ma Y, Zhang X, Shen B, Lu Y, Chen W, Ma J, et al. Generating rats with conditional alleles using CRISPR/Cas9. Cell Res. 2014;24:122-5 pubmed publisher
  51. Fang X, Zhou J, Liu X. Pharmacokinetics of sarafloxacin in allogynogenetic silver crucian carp, Carassius auratus gibelio. Fish Physiol Biochem. 2016;42:335-41 pubmed publisher
    ..15%. Based on a minimum inhibitory concentration (MIC) of 0.00625 to 0.045 μg/mL for susceptible strains, sarafloxacin p.o. administration at a dose 10 mg/kg could be efficacious against common pathogenic bacteria of fish. ..
  52. Yi L, Wang Y, Ma Z, Lin H, Xu B, Grenier D, et al. Identification and characterization of a Streptococcus equi ssp. zooepidemicus immunogenic GroEL protein involved in biofilm formation. Vet Res. 2016;47:50 pubmed publisher
    ..equi spp. zooepidemicus infections. It may therefore be a candidate of interest to be included in vaccines against S. equi spp. zooepidemicus infections. ..
  53. Chao Y, Zhu L, Qu X, Zhang J, Zhang J, Kong X, et al. Inhibition of angiotension II type 1 receptor reduced human endothelial inflammation induced by low shear stress. Exp Cell Res. 2017;360:94-104 pubmed publisher
    ..These findings demonstrate that LSS induces endothelial inflammation via AT1R/ERK signaling and that Losartan has beneficial effects on endothelial inflammation. ..
  54. Zhan M. Determination of photochemically-generated reactive oxygen species in natural water. J Environ Sci (China). 2009;21:303-6 pubmed
    ..The steady-state concentrations of *OH was 1.27x10(-14) mol/L in a nitrate solution, and the second-order rate constant of BPA with *OH was 1.01 x 10(10) L/(mol x s). ..
  55. Ren S, Fengyu -, Zuo S, Zhao M, Wang X, Wang X, et al. Inhibition of tumor angiogenesis in lung cancer by T4 phage surface displaying mVEGFR2 vaccine. Vaccine. 2011;29:5802-11 pubmed publisher
    ..Antitumor activity and autoantibody production of mVEGFR2 could be neutralized by the depletion of CD4+T lymphocytes. These studies strongly suggest that T4-mVEGFR2 recombinant vaccine might be a promising antitumor approach. ..
  56. Chen Z, Xu S, Zhou K, Yang G. Whale phylogeny and rapid radiation events revealed using novel retroposed elements and their flanking sequences. BMC Evol Biol. 2011;11:314 pubmed publisher
  57. Xu B, Chen W, Fan Z, Han Y, Xiong X, Gao X, et al. Responses of neurons in paraventricular nucleus to activation of cardiac afferents and acute myocardial ischaemia in rats. Exp Physiol. 2011;96:295-304 pubmed publisher
    ..Acute myocardial ischaemia activates capsaicin-sensitive neurons in PVN and enhances sympathetic outflow. ..
  58. Li J, Wang C, Chen J, Feng Z, Ma H. Expression of liver insulin-like growth factor 1 gene and its serum level in patients with diabetes. World J Gastroenterol. 2004;10:255-9 pubmed
    ..Accordingly serum IGF-1 level decreases. This might indicate that liver tissue IGF-1 gene expression is greatly affected in diabetes, thus contributing to reduction of serum IGF-1 level. ..
  59. Guo Q, You Q, Wu Z, Yuan S, Zhao L. General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice. Acta Pharmacol Sin. 2004;25:769-74 pubmed
    ..To study the inhibitory effect of general gambogic acids (GGA) on transplantation tumor SMMC-7721 in experimental animal model and SMMC-7721 cells in vitro...
  60. Xia X, Cheng G, Pan Y, Xia Z, Kong L. Behavioral, neurochemical and neuroendocrine effects of the ethanolic extract from Curcuma longa L. in the mouse forced swimming test. J Ethnopharmacol. 2007;110:356-63 pubmed
    ..These results suggested that antidepressant properties of the ethanolic extract of Curcuma longa was mediated through regulations of neurochemical and neuroendocrine systems and it may be a useful agent against depression. ..
  61. Tang B, Zhang J, Yu L, Li H, Zhu J, Wang J. Excitation of histamine on neuronal activity of cerebellar fastigial nucleus in rat. Inflamm Res. 2008;57 Suppl 1:S41-2 pubmed publisher
  62. Zhang C, Chen X, Wang B, Liu F, Chi X, Tong M, et al. Over-expression of NYGGF4 inhibits glucose transport in 3T3-L1 adipocytes via attenuated phosphorylation of IRS-1 and Akt. Acta Pharmacol Sin. 2009;30:120-4 pubmed publisher
    ..These observations highlight the potential role of NYGGF4 in glucose homeostasis and possibly in the pathogenesis of obesity. ..
  63. Che C, Pang X, Hua X, Zhang B, Shen J, Zhu J, et al. Effects of human fecal flora on intestinal morphology and mucosal immunity in human flora-associated piglet. Scand J Immunol. 2009;69:223-33 pubmed publisher
    ..This study confirms that the composition of gut microbes differentially affects the host intestinal mucosal immunity and suggests that commensal bacteria have great effects on intestinal health and development. ..
  64. Qian J, Hua H, Qin S. [Progress on antitumor effects of Marsdenia tenacissima]. Zhongguo Zhong Yao Za Zhi. 2009;34:11-3 pubmed
    ..It provides theoretical evidences for study on constituents in this traditional Chinese medicine. Futher studies on the species in M. tenacissima are needed for better medicinal utilization. ..
  65. Tao X, Liu H, Shi S, Han X, Lin C, Yao B. [Expression of rat annexin 5 and its effect on human sperm motility in vitro]. Zhonghua Nan Ke Xue. 2010;16:400-4 pubmed
    ..84 +/- 6.35 vs. 49.5 +/- 12.27, P < 0.01). An annexin 5 recombinant expression vector was successfully constructed. The protein annexin 5 can be efficiently expressed in E. coli and effectively improve human sperm motility in vitro. ..
  66. Huang Z, Dong L, Chen J, Gao F, Zhang Z, Chen J, et al. Low-molecular weight chitosan/vascular endothelial growth factor short hairpin RNA for the treatment of hepatocellular carcinoma. Life Sci. 2012;91:1207-15 pubmed publisher
    ..This study demonstrated the feasibility of using LMWC as a potential carrier for RNA interference drugs in liver cancer therapy. ..
  67. Xu P, Zhang X, Miao C, Fu Z, Li Z, Zhang G, et al. Promotion of melanoma cell invasion and tumor metastasis by microcystin-LR via phosphatidylinositol 3-kinase/AKT pathway. Environ Sci Technol. 2013;47:8801-8 pubmed publisher
  68. Li M, Wang J, Lu Z, Wei D, Yang M, Kong L. NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus). Aquat Toxicol. 2014;146:82-92 pubmed publisher
  69. Dong J, Wang H, Wu G, Zhao J, Zhang L, Zuo L, et al. Oral treatment with SEW2871, a sphingosine-1-phosphate type 1 receptor agonist, ameliorates experimental colitis in interleukin-10 gene deficient mice. Clin Exp Immunol. 2014;177:94-101 pubmed publisher
    ..SEW2871 treatment ameliorates established experimental colitis in IL-10(-/-) mice, which may provide a new therapeutic approach for human CD therapy. ..
  70. Ju L, Jia M, Sun J, Sun X, Zhang H, Ji M, et al. Hypermethylation of Hippocampal Synaptic Plasticity-Related genes is Involved in Neonatal Sevoflurane Exposure-Induced Cognitive Impairments in Rats. Neurotox Res. 2016;29:243-55 pubmed publisher
    ..In conclusion, our results suggest that hypermethylation of hippocampal BDNF and Reelin is involved in neonatal sevoflurane exposure-induced cognitive impairments. ..
  71. Xu Z, Huang H, Chen Y, Gao Y, Xu J, Marshall C, et al. Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis. J Alzheimers Dis. 2016;51:179-95 pubmed publisher
  72. Jiang X, Geng F, Wang Y, Liu J, Qu P, Xu M. Fluorescence turn-on and colorimetric dual readout assay of glutathione over cysteine based on the fluorescence inner-filter effect of oxidized TMB on TMPyP. Biosens Bioelectron. 2016;81:268-273 pubmed publisher
    ..1μM to 20μM along with a limit of detection (LOD) of about 30nM (calculated LOD as 3σ/slope). Finally, this novel sensor was successfully applied for GSH detection in fetal calf serum, and satisfactory recovery was achieved. ..
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