Experts and Doctors on biosensing techniques in Changsha, Hunan, China


Locale: Changsha, Hunan, China
Topic: biosensing techniques

Top Publications

  1. Li J, Tan W, Wang K, Xiao D, Yang X, He X, et al. Ultrasensitive optical DNA biosensor based on surface immobilization of molecular beacon by a bridge structure. Anal Sci. 2001;17:1149-53 pubmed
    ..It was interesting to note that the described biosensor was reproducible after being regenerated by urea...
  2. Qu B, Chu X, Shen G, Yu R. A novel electrochemical immunosensor based on colabeled silica nanoparticles for determination of total prostate specific antigen in human serum. Talanta. 2008;76:785-90 pubmed publisher
  3. Wu Z, Wu Z, Tang H, Tang L, Jiang J. Activity-based DNA-gold nanoparticle probe as colorimetric biosensor for DNA methyltransferase/glycosylase assay. Anal Chem. 2013;85:4376-83 pubmed publisher
    ..Our strategy can also be used as a promising and convenient approach for visualized screening of ABPs for DNA modifying enzymes. ..
  4. Liu X, Deng Y, Jin X, Chen L, Jiang J, Shen G, et al. Ultrasensitive electrochemical immunosensor for ochratoxin A using gold colloid-mediated hapten immobilization. Anal Biochem. 2009;389:63-8 pubmed publisher
    ..2 pg/ml. Furthermore, a negligible matrix effect and good recoveries were obtained in the determination of corn samples, evidencing the feasibility of the proposed method for accurate determination of OTA in corn samples...
  5. Xiao C, Chu X, Yang Y, Li X, Zhang X, Chen J. Hollow nitrogen-doped carbon microspheres pyrolyzed from self-polymerized dopamine and its application in simultaneous electrochemical determination of uric acid, ascorbic acid and dopamine. Biosens Bioelectron. 2011;26:2934-9 pubmed publisher
    ..The attractive features of HNCMS provide potential applications in the simultaneous determination of UA, AA and DA. ..
  6. Pan D, Chen J, Nie L, Tao W, Yao S. An amperometric glucose biosensor based on poly(o-aminophenol) and Prussian blue films at platinum electrode. Anal Biochem. 2004;324:115-22 pubmed
    ..In addition, effects of temperature, applied potential used in the determination, pH value of the detection solution, and electroactive interferents on the amperometric response of the sensor were investigated and are discussed. ..
  7. Li H, Guo Y, Xiao L, Chen B. Selective and sensitive detection of acetylcholinesterase activity using denatured protein-protected gold nanoclusters as a label-free probe. Analyst. 2014;139:285-9 pubmed publisher
    ..Other enzymes and metal ions, i.e., GPT, ?-GT, GOx, K(+), Ca(2+) and Na(+), showed minimal interference. Using the fluorescence probe, satisfactory results for the detection of the AChE activity in human serum were obtained. ..
  8. Ding X, Li H, Deng L, Peng Z, Chen H, Wang D. A novel homogenous detection method based on the self-assembled DNAzyme labeled DNA probes with SWNT conjugates and its application in detecting pathogen. Biosens Bioelectron. 2011;26:4596-600 pubmed publisher
    ..aureus quantitatively. In addition, this work proved that the method obtain higher detection sensitivity compared with the method without SWNTs because of the protection profile of SWNTs towards the detection probe. ..
  9. Chen B, Ma M, Su X. An amperometric penicillin biosensor with enhanced sensitivity based on co-immobilization of carbon nanotubes, hematein, and beta-lactamase on glassy carbon electrode. Anal Chim Acta. 2010;674:89-95 pubmed publisher
    ..The electrode-to-electrode variation of the response sensitivity was 7.0% RSD...

More Information


  1. Sun C, Liu X, Feng K, Jiang J, Shen G, Yu R. An aptazyme-based electrochemical biosensor for the detection of adenosine. Anal Chim Acta. 2010;669:87-93 pubmed publisher
    ..The fabricated sensor is shown to exhibit high sensitivity and desirable selectivity, which might be promising for the rational construction of aptazyme-based biosensors and the determination of adenosine in clinical examination. ..
  2. Tan Y, Chu X, Shen G, Yu R. A signal-amplified electrochemical immunosensor for aflatoxin B(1) determination in rice. Anal Biochem. 2009;387:82-6 pubmed publisher
    ..1 to 10 ng/ml with a detection limit of 0.06 ng/ml. Good recoveries were obtained for the detection of spiked rice samples. So, the proposed method in this article could find a good use for screening AFB(1) in real samples. ..
  3. Zhao J, Zhang Y, Li H, Wen Y, Fan X, Lin F, et al. Ultrasensitive electrochemical aptasensor for thrombin based on the amplification of aptamer-AuNPs-HRP conjugates. Biosens Bioelectron. 2011;26:2297-303 pubmed publisher
    ..This electrochemical aptasensor is simple, rapid (the whole detection period for a thrombin sample is less than 35 min), sensitive and highly specific, it shows promising potential in protein detection and disease diagnosis. ..
  4. Wu Z, Hu P, Zhou H, Shen G, Yu R. Fluorescent oligonucleotide probe based on G-quadruplex scaffold for signal-on ultrasensitive protein assay. Biomaterials. 2010;31:1918-24 pubmed publisher
  5. Deng C, Xia Y, Xiao C, Nie Z, Yang M, Si S. Electrochemical oxidation of purine and pyrimidine bases based on the boron-doped nanotubes modified electrode. Biosens Bioelectron. 2012;31:469-74 pubmed publisher
    ..Therefore, it can be believed that the BCNTs/GC electrode would provide a potential application for the electrochemical detection of DNA in the field of genetic-disease diagnosis...
  6. Huang Y, Wang W, Li Z, Qin X, Bu L, Tang Z, et al. Horseradish peroxidase-catalyzed synthesis of poly(thiophene-3-boronic acid) biocomposites for mono-/bi-enzyme immobilization and amperometric biosensing. Biosens Bioelectron. 2013;44:41-7 pubmed publisher
  7. Liao S, Han W, Ding H, Xie D, Tan H, Yang S, et al. Modulated dye retention for the signal-on fluorometric determination of acetylcholinesterase inhibitor. Anal Chem. 2013;85:4968-73 pubmed publisher
  8. Xie S, Zhou H, Liu D, Shen G, Yu R, Wu Z. In situ amplification signaling-based autonomous aptameric machine for the sensitive fluorescence detection of cocaine. Biosens Bioelectron. 2013;44:95-100 pubmed publisher
  9. Cao Z, Jiang X, Meng W, Xie Q, Yang Q, Ma M, et al. An EQCM study on the interaction of heparin with the charge-transfer complex generated during o-tolidine electrooxidation: a biosensing mode with a dynamically renewed surface. Biosens Bioelectron. 2007;23:348-54 pubmed