Experts and Doctors on base sequence in Wuhan, Hubei, China


Locale: Wuhan, Hubei, China
Topic: base sequence

Top Publications

  1. Yu J, Liu B, Fan B, Zhu M, Xiong T, Yu M, et al. The porcine FBXO32 gene: map assignment, SNP detection and tissue expression. Anim Genet. 2005;36:451-2 pubmed
  2. Fang M, Nie Y, Wang Q, Deng F, Wang R, Wang H, et al. Open reading frame 132 of Helicoverpa armigera nucleopolyhedrovirus encodes a functional per os infectivity factor (PIF-2). J Gen Virol. 2006;87:2563-9 pubmed
    ..Deletion of Ha132 from HearNPV abolished per os infectivity, but had no effect on the infectivity of the budded virus phenotype. ..
  3. Xu R, Li K, Chen G, Xu H, Qiang B, Li C, et al. Characterization of genetic polymorphism of novel MHC B-LB II alleles in Chinese indigenous chickens. J Genet Genomics. 2007;34:109-18 pubmed
    ..These results can provide a molecular biological basis for the study of disease resistance in chicken breeding. ..
  4. Zhang H, Lin L, Zeng C, Shen P, Huang Y. Cloning and characterization of a haloarchaeal heat shock protein 70 functionally expressed in Escherichia coli. FEMS Microbiol Lett. 2007;275:168-74 pubmed publisher
    ..coli dnak-null mutant to propagate lambda phages and grow at 42 degrees C. The results suggested that haloarchaeal Hsp70 should be beneficial for extreme halophiles survival in low-salt environments...
  5. Zhao L, Liu D, Zhang Q, Zhang S, Wan J, Xiao W. Expression and homology modeling of sterol 14alpha-demethylase from Penicillium digitatum. FEMS Microbiol Lett. 2007;277:37-43 pubmed
    ..At the same time, these spectral data suggested that the 3D model and the docking model were reasonable, which we hope can be used to provide a virtual screening of novel DMI drugs. ..
  6. Cui W, Kong X, Cao H, Wang X, Gao J, Wu R, et al. [Mutations of p53 gene in 41 cases of human brain gliomas]. Ai Zheng. 2008;27:8-11 pubmed
    ..6%). p53 mutations always locate on exons 5 and 8. Missense mutation is major mutant type of p53 gene. p53 mutation plays an important role in the development and malignant transformation of human gliomas. ..
  7. Zhang L, Ding H, Yan J, Hui R, Wang W, Kissling G, et al. Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population. Pharmacogenet Genomics. 2008;18:45-51 pubmed publisher
    ..17-0.67, P=0.002), whereas no significant association was observed in smokers. Collectively, these data indicate a protective influence of the G860A polymorphism of EPHX2 on ischemic stroke in Chinese nonsmokers. ..
  8. Sun T, Zhang Y. Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation. Nucleic Acids Res. 2008;36:1654-64 pubmed publisher
    ..Therefore, interrupting tRNA aminoacylation by the entropy-driven non-specific binding is an important mechanism of pentamidine in inhibiting protein translation, providing new insights into the development of antimicrobial drugs. ..
  9. Yan M, Xiong C, Ye S, Chen Y, Ke M, Zheng F, et al. A novel connexin 50 (GJA8) mutation in a Chinese family with a dominant congenital pulverulent nuclear cataract. Mol Vis. 2008;14:418-24 pubmed
    ..And the mutation was neither found in the 200 controls nor in the 40 senile cataract patients. A novel GJA8 gene mutation was found to be associated with hereditary cataract in a Chinese congenital cataract family. ..

More Information

Publications188 found, 100 shown here

  1. Huang R, Sun X, Hu W, Wang Y, Guo Q. Structure, organization and expression of common carp (Cyprinus carpio L.) SLP-76 gene. Fish Shellfish Immunol. 2008;24:530-41 pubmed publisher
    ..These results suggest that the expression level of SLP-76 gene may be related to thymocyte development in teleosts. ..
  2. Li M, Roh J, Tao X, Yu Z, Liu Z, Liu Q, et al. Cloning and molecular characterization of a novel rolling-circle replicating plasmid, pK1S-1, from Bacillus thuringiensis subsp. kurstaki K1. J Microbiol. 2009;47:466-72 pubmed publisher
    ..thuringiensis strain. The 1.6 kb region that included the putative ORF3 (ReplK), dso and ORF4, exhibited replication ability. These findings identified pKlS-1 as a new RCR group VII plasmid, and determined its replication region. ..
  3. Sen L, Fares M, Liang B, Gao L, Wang B, Wang T, et al. Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns. Biol Direct. 2011;6:29 pubmed publisher
    ..This article was reviewed by Prof. Christian Blouin (nominated by Dr W Ford Doolittle), Dr Endre Barta (nominated by Dr Sandor Pongor), and Dr Nicolas Galtier. ..
  4. Liu H, Fu Y, Li B, Yu X, Xie J, Cheng J, et al. Widespread horizontal gene transfer from circular single-stranded DNA viruses to eukaryotic genomes. BMC Evol Biol. 2011;11:276 pubmed publisher
    ..Our discovery extends the host range of circular ssDNA viruses and sheds light on the origin and evolution of these viruses. It also suggests that ssDNA viruses act as an unforeseen source of genetic innovation in their hosts. ..
  5. Yu Y, Jiang D, Xie J, Cheng J, Li G, Yi X, et al. Ss-Sl2, a novel cell wall protein with PAN modules, is essential for sclerotial development and cellular integrity of Sclerotinia sclerotiorum. PLoS ONE. 2012;7:e34962 pubmed publisher
    ..Hex1-knockdown strains showed similar impairment in maintenance of hyphal integrity as Ss-Sl2 silenced strains. The results suggested that Ss-Sl2 functions in both sclerotial development and cellular integrity of S. sclerotiorum...
  6. Rao H, Deng J, Wang W, Gao Z. An AFLP-based approach for the identification of sex-linked markers in blunt snout bream, Megalobrama amblycephala (Cyprinidae). Genet Mol Res. 2012;11:1027-31 pubmed publisher
    ..However, none showed sex specificity when we converted these three markers into sequence characterized amplified region markers and evaluated all the individuals from the three populations...
  7. Yuan Y, Gao M, Wu D, Liu P, Wu Y. Genome characteristics of a novel phage from Bacillus thuringiensis showing high similarity with phage from Bacillus cereus. PLoS ONE. 2012;7:e37557 pubmed publisher
    ..Based on these observations and analysis of phylogenetic trees, we deduced that B. thuringiensis phage BtCS33 and B. cereus phage W? may have a common distant ancestor. ..
  8. Bi Y, Qiao X, Hua Z, Zhang L, Liu X, Li L, et al. An asymmetric PCR-based, reliable and rapid single-tube native DNA engineering strategy. BMC Biotechnol. 2012;12:39 pubmed publisher
    ..ABI-REC is a novel approach to DNA engineering and gene functional analysis. ..
  9. Zhou M, Yan J, Ma Z, Zhou Y, Abbood N, Liu J, et al. Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events. PLoS ONE. 2012;7:e40649 pubmed publisher
    ..This study shows a model of gene family analysis with gene structure evolution and duplication. ..
  10. Zhu R, Wang J, Lei X, Gui J, Zhang Q. Evidence for Paralichthys olivaceus IFITM1 antiviral effect by impeding viral entry into target cells. Fish Shellfish Immunol. 2013;35:918-26 pubmed publisher
    ..Our current data provide the first evidence that IFITM1 functions as a key effector of the innate immune to restrict virus replication in lower vertebrates, through the action of impeding viral entry. ..
  11. Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, et al. TRIM38 inhibits TNF?- and IL-1?-triggered NF-?B activation by mediating lysosome-dependent degradation of TAB2/3. Proc Natl Acad Sci U S A. 2014;111:1509-14 pubmed publisher
    ..Our findings reveal a previously undiscovered mechanism by which cells keep the inflammatory response in check to avoid excessive harmful immune response triggered by TNF? and IL-1?. ..
  12. Zhou M, Zhang Y, Li X, Wang Z, Tang J, Mu Y, et al. Complete genome sequence of Kocuria flava strain HO-9041, a heavy metal removal bacterium from Xinjiang. J Biotechnol. 2016;220:21-2 pubmed publisher
    ..Here, we report the finished and annotated genome sequence of this organism. ..
  13. You W, Fan Y, Xu Y, Wu K, Tan X. Molecular characterization and functional analysis of PPAR? promoter in yellow catfish Pelteobagrus fulvidraco. Gene. 2017;627:106-113 pubmed publisher
    ..Overall, the present study provided new insights into the mechanisms for transcriptional regulation of PPAR? in fish. ..
  14. Chen X, IJkel W, Tarchini R, Sun X, Sandbrink H, Wang H, et al. The sequence of the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus genome. J Gen Virol. 2001;82:241-57 pubmed
    ..Cluster alignment between group I and group II baculoviruses suggests that they have a common ancestor. ..
  15. Cui Z, Geurts A, Liu G, Kaufman C, Hackett P. Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. J Mol Biol. 2002;318:1221-35 pubmed
    ..These findings have led to the construction of a more advanced transposon that should be useful in gene transfer and insertional mutagenesis in vertebrates. ..
  16. Wang Y, Wang Q, Wang J. [Detection of level and mutation of neurofilament mRNA in Alzheimer's disease]. Zhonghua Yi Xue Za Zhi. 2002;82:519-22 pubmed
    ..No NF-L mutation was found in the samples examined. The increase of neurofilament protein observed in the brains of AD patients is related neither to increased gene transcription nor to mutation of NF mRNA. ..
  17. Hua W, Liang S, Lu Y. A tobacco (Nicotiana tabaccum) calmodulin-binding protein kinase, NtCBK2, is regulated differentially by calmodulin isoforms. Biochem J. 2003;376:291-302 pubmed
  18. Hua Y, Chen X, Xiong J, Zhang Y, Zhu Y. [Isolation and analysis of isolation of differentially-methylated fragment CIDM7 in rice induced by cold stress]. Yi Chuan. 2005;27:595-600 pubmed
    ..CIDM7 is demethylated induced by cold stress. Northern blot analysis confirms that CIDM7 gene expression is up-regulated by cold stress. CIDM7 is single copy and lacated on the Nipponbare chromosome 10 (12.56 Mb-12.57 Mb). ..
  19. Zuo Z, Zhao M, Liu J, Gao G, Wu X. Functional analysis of bladder cancer-related protein gene: a putative cervical cancer tumor suppressor gene in cervical carcinoma. Tumour Biol. 2006;27:221-6 pubmed
    ..BLCAP expression in HeLa cells leads to growth arrest and significantly enhanced apoptosis in vitro and reduced tumor formation in vivo. Thus, BLCAP might be a potential tumor suppressor gene in cervical carcinoma. ..
  20. Guo M, Wang D, Shao H, Qiu H, Xue L, Zhao Z, et al. Transcription of human zinc finger ZNF268 gene requires an intragenic promoter element. J Biol Chem. 2006;281:24623-36 pubmed
    ..These results demonstrate that the human ZNF268 gene promoter is atypical and requires an intragenic element located within the first exon that mediates the effect of CREB for its activity. ..
  21. Liu Q, Zhou Y, Zhou D, Liu E, Du K, Chen S, et al. Semi-nested PCR detection of Babesia orientalis in its natural hosts Rhipicephalus haemaphysaloides and buffalo. Vet Parasitol. 2007;143:260-6 pubmed
    ..The results showed that the semi-nested PCR was a useful method to investigate the epidemiology of buffalo babesiosis (B. orientalis), which is widely distributed in Hubei province, China...
  22. Qiu H, Xu X, Zhao S, Fan B, Yerle M, Liu B. Somatic cell hybrid and RH mapping of the porcine LGALS1, ITGA7, ITGB1, LGALS3, NOL12, GGA1, SH3BP1 and PDXP genes. Anim Genet. 2007;38:315-6 pubmed
  23. Shijin Y, Hong Y, Yibao M, Zongyun C, Han S, Yingliang W, et al. Characterization of a new Kv1.3 channel-specific blocker, J123, from the scorpion Buthus martensii Karsch. Peptides. 2008;29:1514-20 pubmed publisher
    ..All these data not only enrich the knowledge of the structure-function relationship of the new Kv1.3-speicific peptide but also present a potential drug candidate for selectively targeting Kv1.3 channels...
  24. Wu S, Wang G, Xi B, Gao D, Nie P. Molecular characteristics of Camallanus Spp. (Spirurida: Camallanidae) in fishes from China based on its rDNA sequences. J Parasitol. 2008;94:731-6 pubmed publisher
    ..cotti and C. hypophthalmichthys from different fish species in various geographical locations, although the interior nodes of each clade received poor support...
  25. Liu J, Tan C, Li J, Chen H, Xu P, He Q, et al. Characterization of ISApl1, an insertion element identified from Actinobacillus pleuropneumoniae field isolate in China. Vet Microbiol. 2008;132:348-54 pubmed publisher
    ..The genotype of the pgaC(-)/IS(+) was not altered after re-isolation from challenged mice, which indicated that this IS element was relatively stable in A. pleuropneumoniae during infection. ..
  26. Guo L, Fu C, Miao W. Cloning, characterization, and gene expression analysis of a novel cadmium metallothionein gene in Tetrahymena pigmentosa. Gene. 2008;423:29-35 pubmed publisher
    ..The genetic diversity of Tetrahymena MT genes is discussed in relation to the unique structure of the Tpig-MT1 gene and other reported Cd-MT isoforms. ..
  27. Kang M, Zhou R, Liu L, Langford P, Chen H. Analysis of an Actinobacillus pleuropneumoniae multi-resistance plasmid, pHB0503. Plasmid. 2009;61:135-9 pubmed publisher
    ..This is the first report of a complete sequence of the plasmid containing seven resistance genes from A. pleuropneumoniae...
  28. Lan J, Lei M, Zhang Y, Wang J, Feng X, Xu D, et al. Characterization of the porcine differentially expressed PDK4 gene and association with meat quality. Mol Biol Rep. 2009;36:2003-10 pubmed publisher
    ..The deduced amino acid sequence showed conservation in evolution. A G/A mutation in intron 9 was identified and association analysis showed that it was significantly associated with intramuscular fat, muscle water content. ..
  29. Shen H, Zhao S, Cao J, Li X, Fan B. Porcine MuRF2 and MuRF3: molecular cloning, expression and association analysis with muscle production traits. Mol Biol Rep. 2011;38:5115-23 pubmed publisher
    ..The study suggested that the porcine MuRF2 and MuRF3 genes are involved in the muscle growth and development, and can be considered as potential candidate genes affecting muscle production traits in the pig. ..
  30. Zhao J, Jiang Y, Lei Y, Zou K, Wang C, Huang S, et al. Functional MICA-129 polymorphism and serum levels of soluble MICA are correlated with ulcerative colitis in Chinese patients. J Gastroenterol Hepatol. 2011;26:593-8 pubmed publisher
    ..Our findings showed that the MICA-129 gene polymorphism as a functionally relevant gene was associated with UC and seems to play a potential role in the development of UC in patients in central China. ..
  31. Liu Y, Wu W, Zuo B, Ren Z, Xiong Y. [Polymorphism in coding region of pig PRDX6 gene and its genetic effects analysis]. Yi Chuan. 2011;33:743-8 pubmed
    ..05). Allele A was predominant in western pig breeds, while allele G was predominant in Chinese indigenous breeds. These two SNPs were likely to be important markers affecting meat quality traits (especially the muscle tenderness). ..
  32. Li X, Yuan D, Wang H, Chen X, Wang B, Lin Z, et al. Increasing cotton genome coverage with polymorphic SSRs as revealed by SSCP. Genome. 2012;55:459-70 pubmed publisher
    ..The technique discussed in the present study enables us to detect polymorphism of monomorphic SSRs, and increase the utilization efficiency of the existing SSR primers. ..
  33. Dong L, Liu Y, Qiu Y, Peng B, Yin J, Liu W, et al. Identification of Pirh2E and Pirh2F, two additional novel isoforms of Pirh2 ubiquitin ligase from human hepatocellular liver carcinoma cell line. Biomed Mater Eng. 2012;22:89-95 pubmed publisher
    ..Further studies are required to determine whether Pirh2E and Pirh2F functions in a manner similar to Pirh2A. ..
  34. Pan C, You Y, Diao Y, Hu Z, Chen J. Isolation and characterization of microsatellite loci for the herbaceous tuber crop, Amorphophallus konjac (Araceae). Genet Mol Res. 2012;11:4617-21 pubmed publisher
    ..844, respectively, in the two populations. These microsatellite markers will facilitate further studies in population genetics and utilization of A. konjac. ..
  35. Liang H, Li Z, Zou G. Complete mitochondrial DNA genome of Leiocassis crassilabris(Siluriformes: Bagridae). Mitochondrial DNA. 2013;24:222-4 pubmed publisher
    ..4% C, and 14.9% G, with a high A+T content (58.7%). This is the first report on the complete mitogenome sequence of L. crassilabris, which can provide a basic data for the studies on phylogenetic analysis and conservation genetics. ..
  36. Zhang L, He Z. Radiation-sensitive gene A (RadA) targets DisA, DNA integrity scanning protein A, to negatively affect cyclic Di-AMP synthesis activity in Mycobacterium smegmatis. J Biol Chem. 2013;288:22426-36 pubmed publisher
    ..Our findings enhance our understanding of the control of c-di-AMP synthesis and its physiological roles in bacteria...
  37. Wei W, Zhang W, Bai J, Zhang H, Zhao Y, Li X, et al. The NF-κB-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes. J Cell Sci. 2016;129:39-50 pubmed publisher
    ..Our data illustrate that the signaling pathway NF-κB-miR-195/497-Igf1r/Insr-Ccnd2/Ccne1 plays important roles in myogenesis. Our study provides novel evidence for the roles of miR-195 and miR-497 in muscle development. ..
  38. Ren X, Bu B, Yao Q, Qiu X, Liu J, Wang Q, et al. [Mutation of Thr704Met in SCN 4A causes normoKPP in a Chinese family]. Yi Chuan. 2006;28:923-6 pubmed
    ..This mutation should be responsible for normoKPP in this family. ..
  39. Sun M, Liu X, Cao S, He Q, Zhou R, Ye J, et al. Inhibition of porcine circovirus type 1 and type 2 production in PK-15 cells by small interfering RNAs targeting the Rep gene. Vet Microbiol. 2007;123:203-9 pubmed
    ..Taken together, our data suggest that RNAi could be investigated as a potential treatment for PCV infection. ..
  40. An H, Zhang L, Tang Y, Luo X, Sun T, Li Y, et al. Skermanella xinjiangensis sp. nov., isolated from the desert of Xinjiang, China. Int J Syst Evol Microbiol. 2009;59:1531-4 pubmed publisher
    ..nov. is proposed. The type strain is 10-1-101(T) (=CCTCC AB 207153(T)=NRRL B-51273(T))...
  41. Li S, Ma Y, Jang S, Wu Y, Liu H, Cao Z, et al. A HindIII BAC library construction of Mesobuthus martensii Karsch (Scorpiones:Buthidae): an important genetic resource for comparative genomics and phylogenetic analysis. Genes Genet Syst. 2009;84:417-24 pubmed
    ..These results demonstrated that the BAC library of the scorpion M. martensii Karsch and the complete sequence of rDNA unit will provide important genetic resources and tools for comparative genomics and phylogenetic analysis. ..
  42. Liu M, Xu D, Peng J, Zheng R, Li F, Jiang S. cDNA cloning and characterization of 5' upstream promoter region of porcine mef2c gene. Mol Biol Rep. 2011;38:4723-30 pubmed publisher
    ..These results may be useful for elucidating the regulation mechanisms of mef2c, which interacts with other factors to regulate target genes. ..
  43. Zhuo R, Ma L, Fan F, Gong Y, Wan X, Jiang M, et al. Decolorization of different dyes by a newly isolated white-rot fungi strain Ganoderma sp.En3 and cloning and functional analysis of its laccase gene. J Hazard Mater. 2011;192:855-73 pubmed publisher
    ..In addition, the 5'-flanking sequence upstream of the start codon ATG in lac-En3-1 gene was obtained. Many putative cis-acting responsive elements were predicted in the promoter region of lac-En3-1. ..
  44. Wang C, Li Y, Shi L, Ren J, Patti M, Wang T, et al. Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis. Nat Genet. 2012;44:254-6 pubmed publisher
    ..Our results implicate altered phosphate homeostasis in the etiology of IBGC...
  45. Tao P, Wang J. Characterization of the variable 3' UTR and expression of the two intron-containing KIN transcripts from Capsella bursa-pastoris. Gene. 2012;507:99-105 pubmed publisher
    ..CbKIN1-U and CbKIN2-U share similar gene expression profiles in development and in response to exposure to different stresses, suggesting that they probably play similar biological roles in C. bursa-pastoris...
  46. Feng J, Liu B, Zhang Z, Ren Y, Li Y, Gan F, et al. The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable of growth on synthetic media without amino acid supplements. PLoS ONE. 2012;7:e41621 pubmed publisher
    ..Finally, our phylogenetic analysis of haloarchaeal genomes provides clues about evolutionary relationships of haloarchaea. ..
  47. Xiong F, Li W, Wu S, Zou H, Wang G. Molecular phylogeny and host specificity of the larval Eustrongylides (Nematoda: Dioctophmidae) from freshwater fish in China. J Parasitol. 2013;99:137-44 pubmed publisher
    ..Clade 3 was found in 9 species, but its low prevalence suggests accidental infection in all species. Although the larval nematode presented low host specificity, it exhibited some host preference...
  48. Yuan X, Li A, Liang X, Huang W, Song Y, He S, et al. Leptin expression in mandarin fish Siniperca chuatsi (Basilewsky): Regulation by postprandial and short-term fasting treatment. Comp Biochem Physiol A Mol Integr Physiol. 2016;194:8-18 pubmed publisher
  49. Zhou H, Zheng C, Su J, Chen B, Fu Y, Xie Y, et al. Characterization of a natural triple-tandem c-di-GMP riboswitch and application of the riboswitch-based dual-fluorescence reporter. Sci Rep. 2016;6:20871 pubmed publisher
    ..This report represented the first native triple-tandem riboswitch that was applied to serve as a riboswitch-based dual-fluorescence reporter for the efficient and convenient verification of putative DGC activity in vivo. ..
  50. Tang D, Zhou X, Li X, Zhao L, Liu F. Variation of mitochondrial gene and the association with type 2 diabetes mellitus in a Chinese population. Diabetes Res Clin Pract. 2006;73:77-82 pubmed
    ..043, P=0.037). Our results suggest that the mutations of T3394C and A14693G may contribute to genetic predisposition to T2DM, with the T16189C variant being associated with insulin resistance. ..
  51. Song Y, Zhang W, Peng B, Wang C, Wang Q, Bian Z. Germline mutations of the PTCH gene in families with odontogenic keratocysts and nevoid basal cell carcinoma syndrome. Tumour Biol. 2006;27:175-80 pubmed
    ..The results suggest that germline mutations on PTCH can cause isolated OKC, and that the PTCH gene responsible for NBCCS plays an important role in the formation of OKCs even when they are not syndrome-related. ..
  52. Cao J, Yu J, Liu C, Zhou L, Yu H. Effects of gastrin 17 on beta-catenin/Tcf-4 pathway in Colo320WT colon cancer cells. World J Gastroenterol. 2006;12:7482-7 pubmed
    ..In addition, the aforementioned G17-stimulated responses were blocked by L365,260. Gastrin17 activates beta-catenin/Tcf-4 signaling in Colo320WT cells, thereby leading to over-expression of c-myc and cyclin D1. ..
  53. Ying Y, Wei H, Cao L, Lu J, Luo X. Clinical features and growth hormone receptor gene mutations of patients with Laron syndrome from a Chinese family. Zhongguo Dang Dai Er Ke Za Zhi. 2007;9:335-8 pubmed
    ..The S65H mutation might be the cause of Laron syndrome in the two patients...
  54. Xia L, Huang W, Wu J, Yang Y, Zhang Q, Zhou Z, et al. HBx protein induces expression of MIG and increases migration of leukocytes through activation of NF-kappaB. Virology. 2009;385:335-42 pubmed publisher
    ..Our findings provide a new insight into how leukocytes migrate to liver, and disclose a new regulatory mechanism of MIG expression after HBV infection...
  55. Du H, Zheng J, Wu M, Zhao Q, Wang D. High MHC DQB variation and asymmetric allelic distribution in the endangered Yangtze finless porpoise, Neophocaena phocaenoides asiaeorientalis. Biochem Genet. 2010;48:433-49 pubmed publisher
  56. Guo H, Zou P, Fu J, Guo Z, Zhu B, Nie P, et al. Characterization of two C-type lectin-like domain (CTLD)-containing proteins from the cDNA library of Chinese mitten crab Eriocheir sinensis. Fish Shellfish Immunol. 2011;30:515-24 pubmed publisher
    ..The expression of EsCTLDcp-2 was decreased at the all time points. All these data suggest a differential role of EsCTLDcp-1 and EsCTLDcp-2 in the crab innate immune response to bacterial infection...
  57. Shang H, Li Q, Feng G, Cui Z. Molecular analysis and functions of p53R2 in zebrafish. Gene. 2011;475:30-8 pubmed publisher
    ..Therefore, functions of p53R2 in zebrafish are closely associated with its activity in DNA repair and synthesis. ..
  58. Peng Y, Xiang H, Chen C, Zheng R, Chai J, Peng J, et al. MiR-224 impairs adipocyte early differentiation and regulates fatty acid metabolism. Int J Biochem Cell Biol. 2013;45:1585-93 pubmed publisher
    ..Furthermore, miR-224-5p could regulate fatty acid metabolism through Acyl-CoA synthetase long-chain family member 4 at terminal differentiation. It indicates that miR-224 plays different roles on different stages of adipogenesis. ..
  59. Zhao M, Wang Y, Shen H, Li C, Chen C, Luo Z, et al. Evolution by selection, recombination, and gene duplication in MHC class I genes of two Rhacophoridae species. BMC Evol Biol. 2013;13:113 pubmed publisher
    ..These findings broaden our knowledge on the evolution of amphibian MHC systems. ..
  60. Zhong X, Zhang H, Zhao Y, Sun Q, Hu Y, Peng H, et al. The rice NAD(+)-dependent histone deacetylase OsSRT1 targets preferentially to stress- and metabolism-related genes and transposable elements. PLoS ONE. 2013;8:e66807 pubmed publisher
    ..In addition, OsSRT1 is found to also target to several families of transposable elements, suggesting that OsSRT1 is directly involved in transposable element repression. ..
  61. Fan Y, Rao S, Zeng L, Ma J, Zhou Y, Xu J, et al. Identification and genomic characterization of a novel fish reovirus, Hubei grass carp disease reovirus, isolated in 2009 in China. J Gen Virol. 2013;94:2266-77 pubmed publisher
    ..Based on these observations, we propose that HGDRV is a new species in the genus Aquareovirus that is distantly related to any known species within this genus. ..
  62. Raghupathy R, Zhang X, Alhasani R, Zhou X, Mullin M, Reilly J, et al. Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish. Cell Biochem Funct. 2016;34:429-40 pubmed publisher
    ..Our results indicate KIF3A plays a conserved role in photoreceptor outer segment formation and intracellular transport. ..
  63. Zhang M, Liang Y, Zhang X, Xu Y, Dai H, Xiao W. Deletion of yeast CWP genes enhances cell permeability to genotoxic agents. Toxicol Sci. 2008;103:68-76 pubmed publisher
  64. He L, Liu Q, Quan M, Zhou D, Zhou Y, Zhao J. Molecular cloning and phylogenetic analysis of Babesia orientalis heat shock protein 70. Vet Parasitol. 2009;162:183-91 pubmed publisher
    ..orientalis infected buffalo erythrocytes. These results suggested that hsp70 gene was well conserved among inter-erythrocytic protozoa and the BoHsp70 might be a diagnostic and candidate vaccine antigen...
  65. Xiao J, Jiang H, Zhang R, Fan G, Zhang Y, Jiang D, et al. Augmented cardiac hypertrophy in response to pressure overload in mice lacking ELTD1. PLoS ONE. 2012;7:e35779 pubmed publisher
    ..These effects are suggested to originate from the activation of the ERK and JNK pathways, suggesting that ELTD1 is a potential target for therapies that prevent the development of cardiac disease. ..
  66. Liang T, Wang D, Zhang G, Wei K, Wang W, Zou G. Molecular cloning and expression analysis of two ?-defensin genes in the blunt snout bream (Megalobrama amblycephala). Comp Biochem Physiol B Biochem Mol Biol. 2013;166:91-8 pubmed publisher
    ..The results suggest that ma?D-1 and ma?D-2 may play important roles in protecting blunt snout bream embryos, fry and juveniles from pathogenic microbe invading. ..
  67. Liu F, Qin Y, Yu S, Soares D, Yang L, Weng J, et al. Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish. J Biol Chem. 2017;292:6225-6239 pubmed publisher
    ..Our study also reveals a role of the C-terminal domain of RP2 in maintaining the overall protein stability. ..
  68. Wang X, Wu C, Song X, Chen H, Liu Z. Comparison of pseudorabies virus China reference strain with emerging variants reveals independent virus evolution within specific geographic regions. Virology. 2017;506:92-98 pubmed publisher
  69. Zhang Q, Xiao F, Xie J, Li Z, Gui J. Complete genome sequence of lymphocystis disease virus isolated from China. J Virol. 2004;78:6982-94 pubmed
  70. Li X, Fan X, Wang X, Cai L, Yang W. The cotton ACTIN1 gene is functionally expressed in fibers and participates in fiber elongation. Plant Cell. 2005;17:859-75 pubmed
    ..No defined actin network was observed in these fibers and, consequently, fiber elongation was inhibited. Our results suggested that GhACT1 plays an important role in fiber elongation but not fiber initiation. ..
  71. Gao G, Wu J, Cui T, He Z. [The research on the correlation between eotaxin-3 gene polymorphisms and allergic asthma]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006;23:169-72 pubmed
  72. Wang Y, Zhou L, Li Z, Gui J. Molecular cloning and expression characterization of ApoC-I in the orange-spotted grouper. Fish Physiol Biochem. 2008;34:339-48 pubmed publisher
    ..In transitional gonads, the EcApoC-I expression is restricted to the germ cells. The data suggested that EcApoC-I might play an important role in brain and gonad morphogenesis and growth. ..
  73. Huang R, Zhong S, Liu H, Kong R, Wang Y, Hu W, et al. Identification and characterization of common carp (Cyprinus carpio L.) granzyme A/K, a cytotoxic cell granule-associated serine protease. Fish Shellfish Immunol. 2010;29:388-98 pubmed publisher
    ..These results will help to understand the molecular characterization and the potential role of teleost GzmA/K, a cytotoxic cell granule-associated serine protease. ..
  74. Zeng X, Nie Y, Luo X, Wu S, Shi W, Zhang L, et al. Molecular and bioinformatical characterization of a novel superfamily of cysteine-rich peptides from arthropods. Peptides. 2013;41:45-58 pubmed publisher
    ..The evolution of these genes is dominated by intron sliding and intron loss. ..
  75. Hu T, Wen W, Zhang X, Wang S. Nicking endonuclease-assisted recycling of target-aptamer complex for sensitive electrochemical detection of adenosine triphosphate. Analyst. 2016;141:1506-11 pubmed publisher
    ..The reduced current showed a linear range from 10 nM to 1 μM with a limit of detection as low as 3.4 nM. Furthermore, the proposed strategy can be used for the detection of similar substances. ..
  76. Zhang F, Yin Z, Liu B, Xu J. DNA computation model to solve 0-1 programming problem. Biosystems. 2004;74:9-14 pubmed
    ..The result, verified by biological experimentation, revealed the potential of DNA computation in solving complex programming problem. ..
  77. Chang M, Nie P, Wei L. Short and long peptidoglycan recognition proteins (PGRPs) in zebrafish, with findings of multiple PGRP homologs in teleost fish. Mol Immunol. 2007;44:3005-23 pubmed
  78. Liu J, Li A, Ji C, Yang W. First description of a novel Weissella species as an opportunistic pathogen for rainbow trout Oncorhynchus mykiss (Walbaum) in China. Vet Microbiol. 2009;136:314-20 pubmed publisher
    ..This is the first report of Weissella strains which can cause disease of cultured fish in the world. ..
  79. Ouyang P, Saarel E, Bai Y, Luo C, Lv Q, Xu Y, et al. A de novo mutation in NKX2.5 associated with atrial septal defects, ventricular noncompaction, syncope and sudden death. Clin Chim Acta. 2011;412:170-5 pubmed publisher
    ..3) This study for the first time identifies association between a NKX2.5 mutation and ventricular noncompaction. Our results significantly expand the phenotypic spectrum of NKX2.5 mutations. ..
  80. Luo X, Li L, Zhang S, Lu J, Zeng Y, Zhang H, et al. Therapeutic effects of total coumarins from Urtica dentata Hand on collagen-induced arthritis in Balb/c mice. J Ethnopharmacol. 2011;138:523-9 pubmed publisher
    ..Coumarins are the main active principles contributing to UDH's efficacy, but the mechanisms have not been fully clarified...
  81. Xu W, Bolduc F, Hong N, Perreault J. The use of a combination of computer-assisted structure prediction and SHAPE probing to elucidate the secondary structures of five viroids. Mol Plant Pathol. 2012;13:666-76 pubmed publisher
    ..More importantly, this approach is novel in the study of viroids, and should be of significant aid in the determination of the structures of other RNA species. ..
  82. Zhou S, Ma H, Gao B, Fang G, Zeng Y, Zhang Q, et al. Characterization of a novel disease-causing mutation in exon 1 of SH2D1A gene through amplicon sequencing: a case report on HLH. BMC Med Genet. 2017;18:15 pubmed publisher
    ..This case suggests that genetic test based on amplicon sequencing is a powerful tool for diagnosis of HLH and other diseases caused by genetic defect. ..
  83. Dong C, Li G, Li Z, Zhu H, Zhou M, Hu Z. Molecular cloning and expression analysis of an Mn-SOD gene from Nelumbo nucifera. Appl Biochem Biotechnol. 2009;158:605-14 pubmed publisher
    ..This significant difference demonstrated the differential expression of Mn-SOD in various organs of N. nucifera. ..
  84. Lu J, Chen Z. Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis. Peptides. 2010;31:44-50 pubmed publisher
    ..Our results show that SK84 represents a novel glycine-rich peptide family in Drosophila species with antimicrobial and anti-cancer cell activities. ..
  85. Yi R, Zhu Z, Hu J, Qian Q, Dai J, Ding Y. Identification and expression analysis of microRNAs at the grain filling stage in rice(Oryza sativa L.)via deep sequencing. PLoS ONE. 2013;8:e57863 pubmed publisher
    ..The results provide novel insight into the dynamic profiles of miRNAs in developing rice grain and contribute to the understanding of the regulatory roles of miRNAs in grain filling. ..
  86. Gao J, Zhang C, Fu X, Yi Q, Tian F, Ning Q, et al. Effects of targeted suppression of glutaryl-CoA dehydrogenase by lentivirus-mediated shRNA and excessive intake of lysine on apoptosis in rat striatal neurons. PLoS ONE. 2013;8:e63084 pubmed publisher
    ..These also suggest that GA1-induced striatal degeneration is partially caspase-dependent...
  87. Zhao L, Lu J, Nie P, Li A, Xiong B, Xie H. Roles of plasmid-encoded proteins, EseH, EseI and EscD in invasion, replication and virulence of Edwardsiella ictaluri. Vet Microbiol. 2013;166:233-41 pubmed publisher
    ..Hence, the role of these three genes in adherence, invasion and cellular replication was revealed from the pathogenic bacterium E. ictaluri. ..
  88. Li Y, Fan C, Xing Y, Yun P, Luo L, Yan B, et al. Chalk5 encodes a vacuolar H(+)-translocating pyrophosphatase influencing grain chalkiness in rice. Nat Genet. 2014;46:398-404 pubmed publisher
    ..Our results indicate that two consensus nucleotide polymorphisms in the Chalk5 promoter in rice varieties might partly account for the differences in Chalk5 mRNA levels that contribute to natural variation in grain chalkiness. ..
  89. Cao L, Shen G, Zhu Y, Wang W, Zhao X, Ye Q, et al. Characterization of a single-chain variable fragment (scFv) antibody directed against the human asialoglycoprotein receptor. Biotechnol Appl Biochem. 2006;44:65-72 pubmed
    ..Both antibodies were found to specifically recognize denatured and native forms of the ASGPR and thus could potentially be used as targeting molecules for gene therapy of hepatocellular carcinoma or other liver diseases. ..
  90. Lu J, Zhang J, Wang X, Jiang H, Liu C, Hu Y. In vitro and in vivo identification of structural and sequence elements in the 5' untranslated region of Ectropis obliqua picorna-like virus required for internal initiation. J Gen Virol. 2006;87:3667-77 pubmed
    ..In conclusion, this study reveals that the EoPV IRES element is unique, although it has features in common with the type II IRESs. ..
  91. Ma G, Huang J, Sun N, Liu X, Zhu M, Wu Z, et al. Molecular characterization of the porcine GBP1 and GBP2 genes. Mol Immunol. 2008;45:2797-807 pubmed publisher
    ..Association analyses revealed that the poGBP1 Eco81I and poGBP2 SspI polymorphisms both had significant associations (p<0.05) with red blood cell count (RBC), haemoglobin concentration (HGB) and hematocrit (HCT) of 17-day-old pigs. ..
  92. Wang D, Fang L, Zhao F, Luo R, Chen H, Xiao S. Molecular cloning, expression and antiviral activity of porcine interleukin-29 (poIL-29). Dev Comp Immunol. 2011;35:378-84 pubmed publisher