Experts and Doctors on viral gene expression regulation in Guangzhou, Guangdong, China
Locale: Guangzhou, Guangdong, China
Topic: viral gene expression regulation
Chen J, Raab Traub N, Yao Q, Zhang F, Huang M, Kuang Z, et al
. [Inhibiting target gene expression and controlling growth of Epstein-Barr virus transformed cells by antisense RNA transcripts]. Ai Zheng. 2002;21:16-20 pubmed
..The results provide a clue to overcome the latent EBV infection in human bodies all living long time and to prevent it inducing NPC in high incidence area by antisense strategies. ..
Li J, Zhang X, Xie D, Deng H, Gao Y, Chen Q, et al
. Expression of immune-related molecules in primary EBV-positive Chinese nasopharyngeal carcinoma: associated with latent membrane protein 1 (LMP1) expression. Cancer Biol Ther. 2007;6:1997-2004 pubmed
..It has been reported that the expression pattern of immune related-molecules on tumor cells will affect the outcome of T-cell-based adoptive immunotherapy for NPC. ..
Ke J, Wang J, Deng R, Wang X. Autographa californica multiple nucleopolyhedrovirus ac66 is required for the efficient egress of nucleocapsids from the nucleus, general synthesis of preoccluded virions and occlusion body formation. Virology. 2008;374:421-31 pubmed publisher
..These results suggested that ac66 plays an important role for the efficient exit of nucleocapsids from the nucleus to the cytoplasm for BV synthesis as well as for preoccluded virion and occlusion synthesis. ..
Li Z, Xu X, Huang L, Wu J, Lu Q, Xiang Z, et al
. Administration of recombinant IFN1 protects zebrafish (Danio rerio) from ISKNV infection. Fish Shellfish Immunol. 2010;29:399-406 pubmed publisher
..This study shows the protective effects of interferon against a DNA-virus in fish for the first time and provides information about the efficacy of fish interferon that will prove useful in possible therapeutic applications. ..
Huang X, Zhao L, Zhang H, Xu X, Jia X, Chen Y, et al
. Shrimp NF-?B binds to the immediate-early gene ie1 promoter of white spot syndrome virus and upregulates its activity. Virology. 2010;406:176-80 pubmed publisher
..We suggested that WSSV may annex the shrimp NF-?B system, which it uses to enhance the expression of viral immediate-early genes...
Yu Z, Wang Z, Chen J, Li H, Lin Z, Zhang F, et al
. GTPase activity is not essential for the interferon-inducible MxA protein to inhibit the replication of hepatitis B virus. Arch Virol. 2008;153:1677-84 pubmed publisher
..In conclusion, GTPase activity is not essential for MxA protein to inhibit HBV replication, and MxA may have only a minimal effect on the replicative cycle of HBV in the nucleus. ..
Wu W, Liang H, Kan J, Liu C, Yuan M, Liang C, et al
. Autographa californica multiple nucleopolyhedrovirus 38K is a novel nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself. J Virol. 2008;82:12356-64 pubmed publisher
..These interactions were confirmed by coimmunoprecipitation assays in vivo. These data demonstrate that 38K is a novel nucleocapsid protein and provide a rationale for why 38K is essential for nucleocapsid assembly...
Gong J, Huang Y, Huang X, Zhang R, Qin Q. Nuclear-export-signal-dependent protein translocation of dUTPase encoded by Singapore grouper iridovirus. Arch Virol. 2010;155:1069-76 pubmed publisher
..These results provide new insights into the pathogenesis of fish iridoviruses...