Experts and Doctors on transcriptional elongation factors in Beijing, China

Summary

Locale: Beijing, China
Topic: transcriptional elongation factors

Top Publications

  1. Liu L, Ai J, Xiao W, Liu J, Wang Y, Xin D, et al. ELL is an HIF-1alpha partner that regulates and responds to hypoxia response in PC3 cells. Prostate. 2010;70:797-805 pubmed publisher
    ..Interestingly, the inhibition was alleviated under hypoxia. Our findings suggest that ELL and HIF-1alpha are binding partners and can modulate the functions of each other in hypoxia. ..
  2. Zhang D, Qin Y. The paradox of elongation factor 4: highly conserved, yet of no physiological significance?. Biochem J. 2013;452:173-81 pubmed publisher
    ..Lastly, we present a hypothesis for back-translocation and discuss the directions future EF4 research should focus on. ..
  3. Liu Z, Zhou Z, Chen G, Bao S. A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation. Biochem Biophys Res Commun. 2007;353:47-53 pubmed
    ..In addition, mouse homolog of hiws1 is found to express ubiquitously in various tissues. ..
  4. Yang J, Zhang X, Feng J, Leng H, Li S, Xiao J, et al. The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly. Cell Rep. 2016;14:1128-1141 pubmed publisher
    ..Therefore, FACT collaborates with CAF-1 and Rtt106 in RC nucleosome assembly. ..
  5. Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, et al. ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia. Nature. 2017;543:265-269 pubmed publisher
  6. Gao Y, Li C, Wei L, Teng Y, Nakajima S, Chen X, et al. SSRP1 Cooperates with PARP and XRCC1 to Facilitate Single-Strand DNA Break Repair by Chromatin Priming. Cancer Res. 2017;77:2674-2685 pubmed publisher
    ..By establishing how SSRP1 facilitates SSB repair, our findings provide a mechanistic rationale to target SSRP1 as a general approach to selectively attack cancer cells. Cancer Res; 77(10); 2674-85. ©2017 AACR. ..
  7. Liu X, Dang Y, Matsu ura T, He Y, He Q, Hong C, et al. DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition. Mol Cell. 2017;67:203-213.e4 pubmed publisher
    ..Together, these results establish circadian clock and cell cycle as interdependent coupled oscillators and identify DNA replication as a critical process in the circadian mechanism. ..