Experts and Doctors on sulfolobus solfataricus in Beijing, China


Locale: Beijing, China
Topic: sulfolobus solfataricus

Top Publications

  1. Xu N, Li Y, Zhao Y, Guo L, Fang Y, Zhao J, et al. Identification and characterization of small RNAs in the hyperthermophilic archaeon Sulfolobus solfataricus. PLoS ONE. 2012;7:e35306 pubmed publisher
    ..Archaea represent a unique life form next to Bacteria and Eukarya, and our results may provide a useful resource for further in-depth study on the regulation and evolution of smRNAs in this special organism. ..
  2. Shi H, Zhang Y, Zhang G, Guo J, Zhang X, Song H, et al. Systematic functional comparative analysis of four single-stranded DNA-binding proteins and their affection on viral RNA metabolism. PLoS ONE. 2013;8:e55076 pubmed publisher
    ..The SSB proteins could also enter the host cell bound to RNA, which resulted in modulation of viral RNA metabolism, particularly ssob and bl21. ..
  3. Chen L, Huang L. Oligonucleotide cleavage and rejoining by topoisomerase III from the hyperthermophilic archaeon Sulfolobus solfataricus: temperature dependence and strand annealing-promoted DNA religation. Mol Microbiol. 2006;60:783-94 pubmed
    ..These results suggest that Sso topo III is well suited for a role in DNA rewinding, whether it leads to homoduplex or heteroduplex formation. ..
  4. Zhang L, Lou H, Guo L, Zhan Z, Duan Z, Guo X, et al. Accurate DNA synthesis by Sulfolobus solfataricus DNA polymerase B1 at high temperature. Extremophiles. 2010;14:107-17 pubmed publisher
    ..These properties of Sso pol B1 are consistent with the proposed role of the enzyme as a replicase in S. solfataricus. ..
  5. Zhu S, Huang R, Gao S, Li X, Zheng G. Discovery and characterization of a second extremely thermostable (+)-γ-lactamase from Sulfolobus solfataricus P2. J Biosci Bioeng. 2016;121:484-90 pubmed publisher
    ..The chiral product of the enzyme was purified to >99% enantiomeric excess. ..
  6. Wu K, Lai X, Guo X, Hu J, Xiang X, Huang L. Interplay between primase and replication factor C in the hyperthermophilic archaeon Sulfolobus solfataricus. Mol Microbiol. 2007;63:826-37 pubmed
    ..These findings suggest that the primase-RFC interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in Archaea. ..
  7. Chu X, Wang L, He Y, Dong Z. [Expression and characterization of chaperonin from Sulfolobus solfataricus P2]. Wei Sheng Wu Xue Bao. 2008;48:1324-9 pubmed
    ..Our research has laid a foundation for the further study on the molecular mechanism of thermoacidophilic archaeon. ..
  8. Zhang Z, Gong Y, Guo L, Jiang T, Huang L. Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA. Mol Microbiol. 2010;76:749-59 pubmed publisher
    ..Structural comparison of Cren7-DNA complexes with Sac7d-DNA complexes reveals significant differences between the two proteins in DNA binding surface, suggesting that Cren7 and Sul7d serve distinct functions in chromosomal organization...
  9. Huang B, Wu H, Hao N, Blombach F, van der Oost J, Li X, et al. Functional study on GTP hydrolysis by the GTP-binding protein from Sulfolobus solfataricus, a member of the HflX family. J Biochem. 2010;148:103-13 pubmed publisher
    ..Together with functional studies of other mutants, we conclude that the classical view of GTP hydrolysis mechanism likely remains the same in the HflX family with a twist in the entity of the nucleophilic alignment...

More Information


  1. Hu J, Guo L, Wu K, Liu B, Lang S, Huang L. Template-dependent polymerization across discontinuous templates by the heterodimeric primase from the hyperthermophilic archaeon Sulfolobus solfataricus. Nucleic Acids Res. 2012;40:3470-83 pubmed publisher
    ..Our results suggest that SsoPriSL is capable of bridging noncomplementary DNA ends and, therefore, may serve a role in double-strand DNA break repair in Archaea...
  2. Ren Y, She Q, Huang L. Transcriptomic analysis of the SSV2 infection of Sulfolobus solfataricus with and without the integrative plasmid pSSVi. Virology. 2013;441:126-34 pubmed publisher
    ..These results provide valuable clues to the understanding of the three-way interactions among SSV2, pSSVi and the host...
  3. Wang Y, Duan Z, Zhu H, Guo X, Wang Z, Zhou J, et al. A novel Sulfolobus non-conjugative extrachromosomal genetic element capable of integration into the host genome and spreading in the presence of a fusellovirus. Virology. 2007;363:124-33 pubmed publisher
    ..In addition, both SSV1 and SSV2 appeared to replicate more efficiently in the presence of pSSVi. Given the versatile genetic abilities, pSSVi appears to be well suited for a role in horizontal gene transfer...
  4. Guo L, Feng Y, Zhang Z, Yao H, Luo Y, Wang J, et al. Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea. Nucleic Acids Res. 2008;36:1129-37 pubmed publisher
    ..These data suggest that the crenarchaeal kingdom in the Archaea shares a common strategy in chromatin organization...
  5. Lin J, Lai S, Jia R, Xu A, Zhang L, Lu J, et al. Structural basis for site-specific ribose methylation by box C/D RNA protein complexes. Nature. 2011;469:559-63 pubmed publisher
    ..Our results reveal the organization of a monomeric C/D RNP and the mechanism underlying its site-specific methylation activity...
  6. Zhu S, Gong C, Song D, Gao S, Zheng G. Discovery of a novel (+)-?-lactamase from Bradyrhizobium japonicum USDA 6 by rational genome mining. Appl Environ Microbiol. 2012;78:7492-5 pubmed
    ..It consists of 409 amino acids, only 49% of which are identical to the amino acid sequences of the known (+)-?-lactamase from Sulfolobus solfataricus. This is only the third (+)-?-lactamase gene to be reported...