Experts and Doctors on multiprotein complexes in Beijing, China


Locale: Beijing, China
Topic: multiprotein complexes

Top Publications

  1. Titushin M, Feng Y, Stepanyuk G, Li Y, Markova S, Golz S, et al. NMR-derived topology of a GFP-photoprotein energy transfer complex. J Biol Chem. 2010;285:40891-900 pubmed publisher
    ..It is suggested that this clytin-cgGFP structure corresponds to the transient complex previously postulated to account for the energy transfer effect of GFP in the bioluminescence of aequorin or Renilla luciferase. ..
  2. Zhou J, Zhang Z, Mi Z, Wang X, Zhang Q, Li X, et al. Characterization of the interface of the bone marrow stromal cell antigen 2-Vpu protein complex via computational chemistry. Biochemistry. 2012;51:1288-96 pubmed publisher
    ..Our results provide a precise model that predicts the detailed interaction occurring between the transmembrane domains of Vpu and BST-2 and should facilitate the design of anti-HIV agents that are able to disrupt this interaction. ..
  3. Guo X, Yu M, Kang X, Yin H. mTOR complex 2 activation by reconstituted high-density lipoprotein prevents senescence in circulating angiogenic cells. Arterioscler Thromb Vasc Biol. 2011;31:1421-9 pubmed publisher
    ..rHDL stimulates sustained mTOR phosphorylation and mTOR-rictor complex formation and inhibits senescence onset in CACs through mTOR complex 2 pathway activation. ..
  4. Zhao B, Wang Z, Yi B, Ma H, Xu H. hRad21 overexpresses and localizes to the ALT-associated promyelocytic leukemia body in ALT cells. Cancer Biol Ther. 2010;9:978-83 pubmed
    ..Thus, one role of hRAD21 appeared to involve telomere maintenance in ALT cells. We suggested that hRAD21 facilitated telomere HR in ALT cells by participating in APB formation. ..
  5. Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed publisher
    ..These data suggest that the phosphorylation of MCM7 on Ser-121 by cyclin/Cdks is involved in preventing DNA rereplication as well as in regulation of the mitotic exit. ..
  6. Zhang J, Zhang H, Gao Z, Hu H, Dong C, Dong Y. Structural basis for recognition of the type VI spike protein VgrG3 by a cognate immunity protein. FEBS Lett. 2014;588:1891-8 pubmed publisher
    ..Here, we determined the crystal structures of native TsaB and the VgrG3C-TsaB complex. VgrG3C adopts a canonical phage-T4-lysozyme-like fold. TsaB interacts with VgrG3C through molecular mimicry, and inserts into the VgrG3C pocket. ..
  7. Jiang L, Liu X, Xiong G, Liu H, Chen F, Wang L, et al. DWARF 53 acts as a repressor of strigolactone signalling in rice. Nature. 2013;504:401-5 pubmed publisher
    ..Moreover, D53 can interact with transcriptional co-repressors known as TOPLESS-RELATED PROTEINS. Our results suggest a model of SL signalling that involves SL-dependent degradation of the D53 repressor mediated by the D14-D3 complex. ..
  8. Yin Y, Hua H, Li M, Liu S, Kong Q, Shao T, et al. mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR. Cell Res. 2016;26:46-65 pubmed publisher
    ..Finally, overexpression of rictor promotes IGF-induced cell proliferation. Our work identifies mTOR as a dual-specificity kinase and clarifies how mTORC2 promotes IGF-IR/InsR activation. ..
  9. Ke M, Zhang Y, Xiong Y, Saeed Y, Deng Y. Identification of protein complexes of microsomes in rat adipocytes by native gel coupled with LC-ESI-QTOF. Mol Biosyst. 2016;12:1313-23 pubmed publisher
    ..The native gel strategy together with our findings should facilitate future studies of the composition of rat adipocyte microsome protein complexes under different conditions. ..

More Information


  1. Deng X, Li W, Chen N, Sun Y, Wei H, Jiang Y, et al. Exploring the priming mechanism of liver regeneration: proteins and protein complexes. Proteomics. 2009;9:2202-16 pubmed publisher
  2. Liu K, Qian L, Wang J, Li W, Deng X, Chen X, et al. Two-dimensional blue native/SDS-PAGE analysis reveals heat shock protein chaperone machinery involved in hepatitis B virus production in HepG2.2.15 cells. Mol Cell Proteomics. 2009;8:495-505 pubmed publisher
    ..2.15 cells. Collectively these results suggest that the interaction of HSP90 with HSP70/HSP60 contributes to the HBV life cycle by forming a multichaperone machine that may constitute therapeutic targets for HBV-associated diseases. ..
  3. Wang J, Hu Q, Chen H, Zhou Z, Li W, Wang Y, et al. Role of individual subunits of the Neurospora crassa CSN complex in regulation of deneddylation and stability of cullin proteins. PLoS Genet. 2010;6:e1001232 pubmed publisher
  4. Liu L, Wu Y, Huang X. Orientin protects myocardial cells against hypoxia-reoxygenation injury through induction of autophagy. Eur J Pharmacol. 2016;776:90-8 pubmed publisher
    ..Our investigation suggests that the cardioprotective effects of orientin during MIRI may be mediated through the balance of autophagy through regulating AMPK, Akt, mTOR, and Bcl-2 associated signaling pathways. ..
  5. Li B, Jia Z, Wang T, Wang W, Zhang C, Chen P, et al. Interaction of Wnt/?-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells. J Cell Biochem. 2012;113:629-39 pubmed publisher
    ..We thus document a specific reciprocal interaction between these two signaling pathways during early stage cardiac differentiation of P19CL6 cells. ..
  6. Qiao S, Luo Q, Zhao Y, ZHANG X, Huang Y. Structural basis for lipopolysaccharide insertion in the bacterial outer membrane. Nature. 2014;511:108-11 pubmed publisher
    ..The crystal structure of the LptD-LptE complex opens the door to new antibiotic strategies targeting the bacterial outer membrane. ..
  7. Peng H, Liu J, Sun Q, Chen R, Wang Y, Duan J, et al. mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development. Oncogene. 2013;32:4702-11 pubmed publisher
    ..In contrast, SOCE agonists should attenuate mTOR inhibitors-mediated AKT reactivation and consequently potentiate their efficacy in the treatment of the patients with TSC. ..
  8. Duan W, Zhou J, Zhang S, Zhao K, Zhao L, Ogata K, et al. ESeroS-GS modulates lipopolysaccharide-induced macrophage activation by impairing the assembly of TLR-4 complexes in lipid rafts. Biochim Biophys Acta. 2011;1813:772-83 pubmed publisher
    ..This article is part of a Special Issue entitled: 11th European Symposium on Calcium. ..
  9. Meng B, Qian Z, Wei F, Wang W, Zhou C, Wang Z, et al. Proteomic analysis on the temperature-dependent complexes in Thermoanaerobacter tengcongensis. Proteomics. 2009;9:3189-200 pubmed publisher
  10. Zhai Y, Li N, Jiang H, Huang X, Gao N, Tye B. Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing. Mol Cell. 2017;67:168-179 pubmed publisher
  11. Guo Y, Dong L, Qiu X, Wang Y, Zhang B, Liu H, et al. Structural basis for hijacking CBF-? and CUL5 E3 ligase complex by HIV-1 Vif. Nature. 2014;505:229-33 pubmed publisher
    ..Together, our data reveal the structural basis for Vif hijacking of the CBF-? and CUL5 E3 ligase complex, laying a foundation for rational design of novel anti-HIV drugs. ..
  12. Yao Q, Cui J, Wang J, Li T, Wan X, Luo T, et al. Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis. Proc Natl Acad Sci U S A. 2012;109:20395-400 pubmed publisher
  13. Huang H, Kang R, Wang J, Luo G, Yang W, Zhao Z. Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. Autophagy. 2013;9:175-95 pubmed publisher
    ..Taken together, our data suggested HCV inhibited the AKT-TSC-MTORC1 pathway via ER stress, resulting in autophagy, which may contribute to the establishment of the HCV-induced autophagy. ..
  14. Yu Y, Wu J, Wang Y, Zhao T, Ma B, Liu Y, et al. Kindlin 2 forms a transcriptional complex with ?-catenin and TCF4 to enhance Wnt signalling. EMBO Rep. 2012;13:750-8 pubmed publisher
    ..Our data indicate that Kindlin 2 is a new regulator of Wnt signalling, providing a mechanistic insight into the role of Kindlin 2 in cancer progression. ..
  15. Wang J, Yu Y, Zhang Z, Quan R, Zhang H, Ma L, et al. Arabidopsis CSN5B interacts with VTC1 and modulates ascorbic acid synthesis. Plant Cell. 2013;25:625-36 pubmed publisher
    ..Together, our data reveal a regulatory role of CSN5B in light-dark regulation of AsA synthesis. ..
  16. Yuan L, Gu R, Xuan Y, Smith Valle E, Loque D, Frommer W, et al. Allosteric regulation of transport activity by heterotrimerization of Arabidopsis ammonium transporter complexes in vivo. Plant Cell. 2013;25:974-84 pubmed publisher
    ..Our study demonstrates in planta a regulatory role in transport activity of heterooligomerization of transporter isoforms, which may enhance their versatility for signal exchange in response to environmental triggers. ..
  17. Zhou Z, Liu X, Hu Q, Zhang N, Sun G, Cha J, et al. Suppression of WC-independent frequency transcription by RCO-1 is essential for Neurospora circadian clock. Proc Natl Acad Sci U S A. 2013;110:E4867-74 pubmed publisher
    ..Together, our results uncover a previously unexpected regulatory mechanism for clock gene transcription...
  18. Wang Y, Lu C, Wei H, Wang N, Chen X, Zhang L, et al. Hepatopoietin interacts directly with COP9 signalosome and regulates AP-1 activity. FEBS Lett. 2004;572:85-91 pubmed
    ..Taken together, these results elucidate a novel relationship of intracellular growth factor, HPO with large protein complex, CSN, which suggests a possible linkage between CSN and liver regeneration. ..
  19. Gao Y, Gao J, Li M, Zheng Y, Wang Y, Zhang H, et al. Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia. J Hematol Oncol. 2016;9:36 pubmed publisher
    ..Our data suggest that Rheb1 promotes AML progression through mTORC1 signaling pathway and combinational drug treatments targeting Rheb1 and mTOR might have a better therapeutic effect on leukemia. ..
  20. Zhu B, Zhu X, Wang L, Liang Y, Feng Q, Pan J. Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis. PLoS Genet. 2017;13:e1006627 pubmed publisher
  21. Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
    ..Collectively, our study reveals a G?L-ubiquitination-dependent switch that fine-tunes the dynamic organization and activation of the mTORC2 kinase under both physiological and pathological conditions. ..
  22. Cui J, Yang Y, Zhang C, Hu P, Kan W, Bai X, et al. FBI-1 functions as a novel AR co-repressor in prostate cancer cells. Cell Mol Life Sci. 2011;68:1091-103 pubmed publisher
    ..Interestingly, FBI-1 plays distinct roles in regulating LNCaP (androgen-dependent) and PC-3 cell (androgen-independent) proliferation. ..
  23. Geng Y, Ju Y, Ren F, Qiu Y, Tomita Y, Tomoeda M, et al. Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/?-catenin signaling through blocking autophagic degradation of dishevelled2. J Biol Chem. 2014;289:11230-41 pubmed publisher
    ..Our findings revealed that IRS1/2 promotes EMT and cell proliferation through stabilizing Dvl2. ..
  24. Zhang X, Sun X, Xue D, Liu D, Hu X, Zhao M, et al. Conformation-dependent scFv antibodies specifically recognize the oligomers assembled from various amyloids and show colocalization of amyloid fibrils with oligomers in patients with amyloidoses. Biochim Biophys Acta. 2011;1814:1703-12 pubmed publisher
  25. Shang Y, Xu X, Duan X, Guo J, Wang Y, Ren F, et al. Hsp70 and Hsp90 oppositely regulate TGF-? signaling through CHIP/Stub1. Biochem Biophys Res Commun. 2014;446:387-92 pubmed publisher
    ..This study provides a new insight into understanding the regulation of the TGF-? signaling by chaperones. ..
  26. Zhang M, Zhang P, Liu Y, Zhou Y. GSK3 inhibitor AR-A014418 promotes osteogenic differentiation of human adipose-derived stem cells via ERK and mTORC2/Akt signaling pathway. Biochem Biophys Res Commun. 2017;490:182-188 pubmed publisher
    ..Our results suggested that AR-A014418 significantly promoted osteogenic potential of hASCs partially by the activation of ERK and mTORC2/Akt signaling pathway, and might be used for bone tissue engineering as an osteo-inductive factor. ..
  27. Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, et al. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proc Natl Acad Sci U S A. 2014;111:E245-54 pubmed publisher
    ..Our results indicate that TRIM14 is a component of the mitochondrial antiviral immunity that facilitates the immune response mediated by retinoic acid-inducible gene-I-like receptors. ..
  28. Shen Q, Qin F, Gao Z, Cui J, Xiao H, Xu Z, et al. Adenine nucleotide translocator cooperates with core cell death machinery to promote apoptosis in Caenorhabditis elegans. Mol Cell Biol. 2009;29:3881-93 pubmed publisher
    ..These findings suggest that WAN-1 is involved in the central cell-killing process and cooperates with the core cell death machinery to promote programmed cell death in C. elegans. ..
  29. Zhang X, Chen Q, Feng J, Hou J, Yang F, Liu J, et al. Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome. J Cell Sci. 2009;122:2240-51 pubmed publisher
  30. Huang X, Ouyang X, Yang P, Lau O, Chen L, Wei N, et al. Conversion from CUL4-based COP1-SPA E3 apparatus to UVR8-COP1-SPA complexes underlies a distinct biochemical function of COP1 under UV-B. Proc Natl Acad Sci U S A. 2013;110:16669-74 pubmed publisher
  31. Wang X, Chen G, Liu H, Zhao Z, Li Z. Four-dimensional orthogonal electrophoresis system for screening protein complexes and protein-protein interactions combined with mass spectrometry. J Proteome Res. 2010;9:5325-34 pubmed publisher
  32. Wu Y, Zhang Y, Zhang H, Yang X, Wang Y, Ren F, et al. p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction. J Biol Chem. 2010;285:34621-31 pubmed publisher
    ..Our data suggest that p15RS inhibits Wnt signaling by interrupting ?-catenin·TCF4 complex formation and that Wnt signaling initiates downstream gene expression by removing p15RS from promoters. ..
  33. Yan J, Li H, Li S, Yao R, Deng H, Xie Q, et al. The Arabidopsis F-box protein CORONATINE INSENSITIVE1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway. Plant Cell. 2013;25:486-98 pubmed publisher
  34. Gao Y, Li T, Chang Y, Wang Y, Zhang W, Li W, et al. Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability. Nat Cell Biol. 2011;13:924-33 pubmed publisher
    ..These results suggest that CUEDC2 is a key regulator of mitosis progression, and that CUEDC2 dysregulation might contribute to tumour development by causing chromosomal instability...
  35. Wang H, Gao J, Wong A, Hu K, Li W, Wang Y, et al. Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans. Biochem J. 2013;449:673-81 pubmed publisher
    ..The results of the present study imply that differential phosphorylation plays a crucial role in RPA (replication protein A) regulation...
  36. Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed publisher
    ..Thus, B cell activation prompts a temporal switch from canonical to noncanonical autophagy that is important in controlling B cell differentiation and fate. ..
  37. Zhou Z, Wang Y, Cai G, He Q. Neurospora COP9 signalosome integrity plays major roles for hyphal growth, conidial development, and circadian function. PLoS Genet. 2012;8:e1002712 pubmed publisher
    ..crassa had little effect on the conidiation circadian rhythm. Our results suggest that CSN integrity plays major roles in hyphal growth, conidial development, and circadian function in N. crassa. ..
  38. Zhang H, Gao Z, Wang W, Liu G, Shtykova E, Xu J, et al. The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6. FEBS Lett. 2012;586:1147-53 pubmed publisher
    ..Structural comparison with other MPN domains, along with bioinformation analysis, suggests that MPN domain from CSN6 may serve as a scaffold instead of a metalloprotease. ..
  39. Wang W, Chen Z, Mao Z, Zhang H, Ding X, Chen S, et al. Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes. EMBO Rep. 2011;12:1160-6 pubmed publisher
    ..Finally, Spindlin1 localizes to the active ribosomal DNA (rDNA) repeats, and Spindlin1 facilitates the expression of rRNA genes. ..
  40. Li J, Deng M, Wei Q, Liu T, Tong X, Ye X. Phosphorylation of MCM3 protein by cyclin E/cyclin-dependent kinase 2 (Cdk2) regulates its function in cell cycle. J Biol Chem. 2011;286:39776-85 pubmed publisher
    ..These data reveal that the phosphorylation of MCM3 contributes to its function in controlling the S phase checkpoint of cell cycle in addition to the regulation of formation of the MCM2-7 complex. ..
  41. Yang J, Zhang X, Feng J, Leng H, Li S, Xiao J, et al. The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly. Cell Rep. 2016;14:1128-1141 pubmed publisher
    ..Therefore, FACT collaborates with CAF-1 and Rtt106 in RC nucleosome assembly. ..
  42. Tao T, Zhou C, Wang Q, Chen X, Sun Q, Zhao T, et al. Rice black streaked dwarf virus P7-2 forms a SCF complex through binding to Oryza sativa SKP1-like proteins, and interacts with GID2 involved in the gibberellin pathway. PLoS ONE. 2017;12:e0177518 pubmed publisher
    ..Overall, these results indicated that P7-2 functioned as a component of the SCF complex in rice, and interaction of P7-2 with GID2 implied possible roles of the GA signaling pathway during RBSDV infection. ..
  43. Zhao A, Fang Y, Chen X, Zhao S, Dong W, Lin Y, et al. Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein. Proc Natl Acad Sci U S A. 2014;111:6630-5 pubmed publisher
    ..We propose a catalytic mechanism model for GluTR, through which photosynthetic organisms can achieve precise regulation of tetrapyrrole biosynthesis. ..
  44. Chen X, Zhu Y, Wang Z, Zhu H, Pan Q, Su S, et al. mTORC1 alters the expression of glycolytic genes by regulating KPNA2 abundances. J Proteomics. 2016;136:13-24 pubmed publisher
  45. Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, et al. mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice. Arterioscler Thromb Vasc Biol. 2017;37:1657-1666 pubmed publisher
    ..Our findings suggest that mTOR-sensitive perturbation of smooth muscle cell mechanosensing contributes to elastin aortopathy. ..
  46. Zhou L, Hang J, Zhou Y, Wan R, Lu G, Yin P, et al. Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature. 2014;506:116-20 pubmed publisher
    ..The structural features and associated biochemical analyses deepen mechanistic understanding of the U6 snRNP function in pre-mRNA splicing. ..
  47. Lin J, Lu J, Feng Y, Sun M, Ye K. An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme. PLoS Biol. 2013;11:e1001669 pubmed publisher
    ..Depletion of snR30 prevents the stable assembly of Rrp7 into preribosomes. Our results provide insight into the evolutionary origin and functional context of Utp22 and Rrp7. ..
  48. Li S, Zhang L, Yao Q, Li L, Dong N, Rong J, et al. Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains. Nature. 2013;501:242-6 pubmed publisher
    ..The mechanism of action of NleB represents a new model by which bacteria counteract host defences, and also a previously unappreciated post-translational modification. ..
  49. Shi H, Shen Q, Qi Y, Yan H, Nie H, Chen Y, et al. BR-SIGNALING KINASE1 physically associates with FLAGELLIN SENSING2 and regulates plant innate immunity in Arabidopsis. Plant Cell. 2013;25:1143-57 pubmed publisher
    ..Our data demonstrate that BSK1 is involved in positive regulation of PTI. Together with previous findings, our work indicates that BSK1 represents a key component directly involved in both BR signaling and plant immunity...
  50. Zhang C, Ning Y, Zhang S, Chen Q, Shao C, Guo Y, et al. IDN2 and its paralogs form a complex required for RNA-directed DNA methylation. PLoS Genet. 2012;8:e1002693 pubmed publisher
  51. Zheng Q, Jin F, Yao C, Zhang T, Zhang G, Ai X. Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells. Biochem Biophys Res Commun. 2012;419:741-7 pubmed publisher
    ..Our study suggests that activation of AMPK by UA contributes to growth inhibition and apoptosis in human bladder cancer cells. ..
  52. Li Q, Shi L, Gui B, Yu W, Wang J, Zhang D, et al. Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14. Cancer Res. 2011;71:6899-908 pubmed publisher
    ..Our findings indicate that CCL14 is a critical mediator of the JARID1B/LSD1/NuRD complex in regulation of angiogenesis and metastasis in breast cancer, identifying a novel potential therapeutic target for breast cancer intervention. ..
  53. Shi L, Sun L, Li Q, Liang J, Yu W, Yi X, et al. Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci U S A. 2011;108:7541-6 pubmed publisher
  54. Sun L, Shi L, Wang F, Huangyang P, Si W, Yang J, et al. Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization. J Biol Chem. 2011;286:4226-35 pubmed publisher
    ..These data may shed new light on the functional connection between CSN, Skp1-Cul1-F-box ubiquitin ligase, and p53 and provide a molecular mechanism for the regulation of JFK-promoted p53 degradation. ..
  55. Chen Y, Yang Z, Meng M, Zhao Y, Dong N, Yan H, et al. Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. Mol Cell. 2009;35:841-55 pubmed publisher
    ..Our studies reveal a previously unknown mechanism for controlling RhoA degradation and regulating RhoA function in various biological contexts, which involves a Cul3/BACURD ubiquitin ligase complex. ..
  56. Wang P, Wang X, Wang F, Cai T, Luo Y. Interaction between Mnk2 and CBC(VHL) ubiquitin ligase E3 complex. Sci China C Life Sci. 2006;49:265-73 pubmed
  57. Liu C, Perrett S, Zhou J. Dimeric trigger factor stably binds folding-competent intermediates and cooperates with the DnaK-DnaJ-GrpE chaperone system to allow refolding. J Biol Chem. 2005;280:13315-20 pubmed
  58. Wang Z, Mu X, Guo M, Wang Y, Teng Z, Mao G, et al. Transforming growth factor-? signaling participates in the maintenance of the primordial follicle pool in the mouse ovary. J Biol Chem. 2014;289:8299-311 pubmed publisher
  59. Li S, Duan J, Li D, Yang B, Dong M, Ye K. Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase. Genes Dev. 2011;25:2409-21 pubmed publisher
    ..Our results reveal significant novel features of eukaryotic H/ACA RNPs. ..
  60. Wang Z, Liu X, Zhao Z, Xu C, Zhang K, Chen C, et al. Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complex. PLoS ONE. 2011;6:e22625 pubmed publisher
    ..The data presented here will help us to better understand the molecular mechanisms of host restriction barriers, host adaptation, and tissue tropism of influenza A virus. ..
  61. Chen H, Shen Y, Tang X, Yu L, Wang J, Guo L, et al. Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex in Mediating Light Control of Development. Plant Cell. 2006;18:1991-2004 pubmed
    ..Thus, this study suggests a biochemical activity connection between CSN and CDD complexes in their cooperation with COP1 in orchestrating the repression of photomorphogenesis. ..