Experts and Doctors on molecular structure in Beijing, China

Summary

Locale: Beijing, China
Topic: molecular structure

Top Publications

  1. Tian X, Wang Y, Yang Q, Yu S, Fang W. Jacaranone analogs from Senecio scandens. J Asian Nat Prod Res. 2009;11:63-8 pubmed publisher
    ..5-1.0 microg/ml against various tumor cell lines. The SAR of these jacaranone analogs (1-8), isolated from S. scandens, was also discussed...
  2. Liu M, Cong X, Li P, Tan J, Chen W, Wang C. Study on the inhibitory mechanism and binding mode of the hydroxycoumarin compound NSC158393 to HIV-1 integrase by molecular modeling. Biopolymers. 2009;91:700-9 pubmed publisher
    ..All the above results are consistent with experiment data, providing us some helpful information for understanding the mechanism of the coumarin-based inhibitors. ..
  3. Yu D, Tian M, Fan Y, Ji G, Wang Y. Aggregate transitions in aqueous solutions of sodium dodecylsulfate with a "gemini-type" organic salt. J Phys Chem B. 2012;116:6425-30 pubmed publisher
    ..This work provides an approach to construct the surfactant systems with the characteristics of gemini surfactants through intermolecular interaction between a two-charged organic salt and oppositely charged single-chain surfactants. ..
  4. Song Y, Zhou G, Zhou S, Jiang Y, Tu P. Polygalins D-G, four new flavonol glycosides from the aerial parts of Polygala sibirica L. (Polygalaceae). Nat Prod Res. 2013;27:1220-7 pubmed publisher
    ..This report is a continuous research work on the systematic chemical investigations of plants of the genus Polygala in our laboratory. ..
  5. Lv L, Yang Q, Zhao Y, Yao C, Sun Y, Yang E, et al. BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis. Planta Med. 2008;74:540-5 pubmed publisher
    ..5 x 10 (-6) M, as well as inhibition of Abeta (1-42) production by 7.4 and 12.3 %, respectively, in B103 neuroblastoma cells at 30 ppm. The preliminary structure-activity relationships of ALOE chromone glucosides were also discussed. ..
  6. Xu R, Jiang L, He J, Liu Y. [The condensation mechanism of sodium new houttuyfonate and determination of the chemical structure of condensation products]. Yao Xue Xue Bao. 2009;44:609-14 pubmed
    ..39 min at 100 degrees C (373 K), separately. It suggests that dimer is an intermediate in condensation reaction, and the end condensation product of sodium new houttuyfonate injection may exist as trimer. ..
  7. Lu J, Hu J, Song Y, Ju Y. A new dual-responsive organogel based on uracil-appended glycyrrhetinic acid. Org Lett. 2011;13:3372-5 pubmed publisher
    ..A novel functional tweezer based on uracil-appended glycyrrhetinic acid with excellent gelation ability was synthesized, and the gel could transform to sol by F(-) and Hg(2+). ..
  8. Li T, Chen J, Li X, Ding X, Wu Y, Zhao L, et al. Absolute quantification of a steroid hormone that regulates development in Caenorhabditis elegans. Anal Chem. 2013;85:9281-7 pubmed publisher
    ..These mutants are able to escape the dauer fate and most of them grow into fertile adults when supplied with exogenous DA. Therefore, a DA spike in the L2 stage is critical for the reproductive development of C. elegans. ..
  9. Qin H, Li Z, Wang P, Si L. [The new secondary metabolite from Polygonatum odoratum]. Zhongguo Zhong Yao Za Zhi. 2004;29:42-4 pubmed
    ..To investigate the chemical constituents of Polygonatum odoratum...

More Information

Publications479 found, 100 shown here

  1. Zhang Y, Lu Y, Zhang L, Zheng Q, Xu L, Yang S. Terpenoids from the roots and rhizomes of Nardostachys chinensis. J Nat Prod. 2005;68:1131-3 pubmed
    ..The structures of the new compounds were established on the basis of their spectroscopic data, and the structure of 1 was confirmed by X-ray crystallographic analysis...
  2. Park K, Ni Z, Côté A, Choi J, Huang R, Uribe Romo F, et al. Exceptional chemical and thermal stability of zeolitic imidazolate frameworks. Proc Natl Acad Sci U S A. 2006;103:10186-10191 pubmed publisher
  3. Cheng S, Qiu F, Huang J, He J. Simultaneous determination of vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn (Crataegus pinnatifida Bge.) leaves by RP-HPLC with ultraviolet photodiode array detection. J Sep Sci. 2007;30:717-21 pubmed
    ..The total amounts of the four flavonoids were 22.2, 62.3, 4.27, and 8.24 mg/g dry weight for vitexin-2"-O-glucoside, vitexin-2"-O-rhamnoside, rutin, and hyperoside in the extract of hawthorn leaves, respectively...
  4. Liu L, Niu S, Lu X, Chen X, Zhang H, Guo L, et al. Unique metabolites of Pestalotiopsis fici suggest a biosynthetic hypothesis involving a Diels-Alder reaction and then mechanistic diversification. Chem Commun (Camb). 2010;46:460-2 pubmed publisher
  5. Kang L, Zhang J, Cong Y, Li B, Xiong C, Zhao Y, et al. Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplatelet aggregation activity. Planta Med. 2012;78:611-6 pubmed publisher
    ..Compounds 1- 13 were evaluated for their platelet aggregation activities, and compound 13 exhibited the strongest inhibitory effect on adenosine diphosphate (ADP)-induced platelet aggregation. ..
  6. Shen Y, Feng Z, Jiang J, Yang Y, Zhang P. Dibenzoyl and isoflavonoid glycosides from Sophora flavescens: inhibition of the cytotoxic effect of D-galactosamine on human hepatocyte HL-7702. J Nat Prod. 2013;76:2337-45 pubmed publisher
    ..Compounds 1, 2, 13, 14, and 19 exhibited weak inhibition of the cytotoxic effect of d-galactosamine on the human hepatic cell line HL-7702. ..
  7. Zhao M, Li J, Shi S, Cai C, Tu P, Tang L, et al. Two new phenolic compounds from the heartwood of Caesalpinia sappan L. Molecules. 2013;19:1-8 pubmed publisher
    ..Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with the high resolution mass spectral data. The NO inhibition activities of two new compounds and six known compounds were tested. ..
  8. Tang Y, Rodríguez Salarichs J, Zhao Y, Cai P, Estévez Gallego J, Balaguer Pérez F, et al. Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by ?III-Tubulin and P-glycoprotein (P-gp) overexpressions. Eur J Med Chem. 2017;137:488-503 pubmed publisher
    ..These observations illustrate a better translation of molecular binding effect to cellular activity by C ring closure and C3' modification than C2 modification in C-seco taxoids. ..
  9. Gu G, Du Y, Linhardt R. Facile synthesis of saponins containing 2,3-branched oligosaccharides by using partially protected glycosyl donors. J Org Chem. 2004;69:5497-500 pubmed
    ..Saponin 2 shows promising cytotoxic activity toward human hepatocellular carcinoma BEL-7402 with an IC50 of <6 microg/mL. ..
  10. Duan B, Huang L, Chen S. Chemical fingerprint analysis of Fritillaria delavayi Franch. by high-performance liquid chromatography. J Sep Sci. 2012;35:513-8 pubmed publisher
    ..The results from the experiment demonstrated that the combinations of the quantitative and chromatographic fingerprint analysis offer an efficient way to evaluate the quality consistency of F. delavayi Franch. ..
  11. Mou Y, Meng J, Fu X, Wang X, Tian J, Wang M, et al. Antimicrobial and antioxidant activities and effect of 1-hexadecene addition on palmarumycin C2 and C3 yields in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Molecules. 2013;18:15587-99 pubmed publisher
    ..Dzf12. Palmarumycin C3 exhibited stronger antimicrobial and antioxidant activities than palmarumycin C2. ..
  12. Feng X. [Analysis of constituents of essential oil from Anemone altaica Fisch. ex C. A. Mey]. Zhongguo Zhong Yao Za Zhi. 1998;23:739-40, 765 pubmed
    ..Analyzing the constituents of the essential oil from Waichangpu(dried rhizome of Anemone altaica, often mistakenly called "Jiujiechangpu")...
  13. Jiang T, Li T, Li J, Fu H, Pei Y, Lin W. Cerebroside analogues from marine-derived fungus Aspergillus flavipes. J Asian Nat Prod Res. 2004;6:249-57 pubmed
    ..Their structures were identified by means of extensive spectroscopic analysis (IR, UV, 2D NMR, MS, CD) and chemical degradation. All four compounds showed cytotoxic activity against the KB cell line. ..
  14. Zhao G, Dong J. [Triterpenoid saponins from flower bud of Jasminum officinale var. grandiflorum]. Zhongguo Zhong Yao Za Zhi. 2008;33:38-42 pubmed
    ..To study the chemical constituent bud of the flowers of Jasminum officinale var. grandiflorum...
  15. Li X, Li Z, Du S, Wang G, Lin R. Two triterpenes from Lysimachia foenum-graecum. J Asian Nat Prod Res. 2009;11:128-31 pubmed publisher
    ..21-O-angeloylbarringtogenol C was a new natural product. These structures were identified on the basis of 1D- and 2D-NMR techniques, including 1H-1H COSY, HMQC, HMBC, TOCSY, and ROESY experiments as well as chemical methods. ..
  16. Li W, Jia H, He X, Shi W, Zhong B. Novel phenoxyalkylcarboxylic acid derivatives as hypolipidaemic agents. J Enzyme Inhib Med Chem. 2012;27:311-8 pubmed publisher
    ..The results indicate that resveratrol should be a better scaffold to derive a new class of hypolipidaemic agents in comparison with a flavonoid scaffold. ..
  17. Li F, Li C, Yang J, Zhang D. Two new neolignans from the stems of Euonymus oblongifolius. J Asian Nat Prod Res. 2012;14:755-8 pubmed publisher
    ..Their chemical structures were determined according to HR-ESI-MS, CD, 1D and 2D NMR spectroscopic analyses...
  18. Shen S, Liu D, Wei C, Proksch P, Lin W. Purpuroines A-J, halogenated alkaloids from the sponge Iotrochota purpurea with antibiotic activity and regulation of tyrosine kinases. Bioorg Med Chem. 2012;20:6924-8 pubmed publisher
    ..Bioassay for the regulation of tyrosine kinases revealed compounds 1 and 4 possessing selective inhibition against the kinase LCK. Primary structure-activity relationship is discussed. ..
  19. Zou Q, Fang Y, Zhao Y, Zhao H, Wang Y, Gu Y, et al. Synthesis and in vitro photocytotoxicity of coumarin derivatives for one- and two-photon excited photodynamic therapy. J Med Chem. 2013;56:5288-94 pubmed publisher
    ..The results showed that derivative 5, with a two-photon absorption cross section value of 1556 GM, could be a powerful PDT agent for both superficial diseases and solid tumors. ..
  20. Feng R, Zhou X, Tan X, Or P, Hu T, Fu J, et al. In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2,3,5-trimethoxy-xanthone purified from Halenia elliptica D. Don. Chem Biol Interact. 2014;210:12-9 pubmed publisher
    ..This study finally provides evidence of substrate inhibition and metabolism-based drug-drug interaction for the medicinal preparations containing HM-1 used in clinic. ..
  21. Li X, Zhang Y, Zhang J, Li X, Cao M, Di Y, et al. Myritonines A-C, Alkaloids from Myrioneuron tonkinensis Based on a Novel Hexacyclic Skeleton. J Nat Prod. 2016;79:1203-7 pubmed publisher
    ..Compounds 1 and 2 showed inhibition against the hepatitis C virus in vitro. ..
  22. Yang Q, Yao C, Fang W. A new triglucosylated naphthalene glycoside from Aloe vera L. Fitoterapia. 2010;81:59-62 pubmed publisher
    ..All these compounds were tested for their BACE inhibitory activity but no significant activities were found. ..
  23. Cheng W, Zhu C, Xu W, Fan X, Yang Y, Li Y, et al. Chemical constituents of the bark of Machilus wangchiana and their biological activities. J Nat Prod. 2009;72:2145-52 pubmed publisher
    ..4 +/- 6.3% to 53.6 +/- 3.5% inhibition at 10(-4) M. Isomahubannolide-23 (14) was cytotoxic against human stomach cancer (BGC-823) and ovarian cancer (A2780) cell lines, with IC(50) values of 0.13 and 2.66 muM, respectively. ..
  24. Zhang L, Ma Z, Che Y, Li N, Tu P. Protective effect of a new amide compound from Pu-erh tea on human micro-vascular endothelial cell against cytotoxicity induced by hydrogen peroxide. Fitoterapia. 2011;82:267-71 pubmed publisher
    ..These results suggested that compound 1 is a very useful compound to prevent H(2)O(2)-induced cell death of HMEC. ..
  25. Zhang Q, Zheng Z, Yu D. Steroidal alkaloids from the bulbs of Fritillaria unibracteata. J Asian Nat Prod Res. 2011;13:1098-103 pubmed publisher
    ..Their structures were fully elucidated by spectroscopic and chemical methods. Compound 1 showed moderate protection effect on neurotoxicity of PC12 cell lines induced by rotenone...
  26. Nan Z, Zeng K, Shi S, Zhao M, Jiang Y, Tu P. Phenylethanoid glycosides with anti-inflammatory activities from the stems of Cistanche deserticola cultured in Tarim desert. Fitoterapia. 2013;89:167-74 pubmed publisher
    ..94 ?M and 14.32 ?M, respectively. ..
  27. Pan X, Huan Y, Shen Z, Liu Z. Synthesis and biological evaluation of novel tetrahydroisoquinoline-C-aryl glucosides as SGLT2 inhibitors for the treatment of type 2 diabetes. Eur J Med Chem. 2016;114:89-100 pubmed publisher
    ..Compared with dapagliflozin, compound 13h exhibited equivalent in vitro inhibitory activity against SGLT2, which might become a promising candidate for the treatment of type 2 diabetes. ..
  28. Zhou Y, Wan X, Wang H, Yan Z, Hou Y, Jin D. Bacterial scavengase p20 is structurally and functionally related to peroxiredoxins. Biochem Biophys Res Commun. 1997;233:848-52 pubmed
    ..Taken together, our findings strongly suggest that the p20 scavengases are structurally and functionally related to peroxiredoxins. ..
  29. Ye M, Yan Y, Guo D. Characterization of phenolic compounds in the Chinese herbal drug Tu-Si-Zi by liquid chromatography coupled to electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2005;19:1469-84 pubmed
    ..The large differences observed between the phenolic constituents of C. chinensis and C. australis strongly encouraged further comparison of the bioactivities of these two species...
  30. Tang L, Jiang Y, Chang H, Zhao M, Tu P, Cui J, et al. Triterpene saponins from the leaves of Ilex kudingcha. J Nat Prod. 2005;68:1169-74 pubmed
    ..The structures and stereochemistry of compounds 1-9 were elucidated by spectroscopic data interpretation and chemical degradation. ..
  31. Zhang B, Li J, Zhang D, Ding Y, Du G. Analgesic and anti-inflammatory activities of a fraction rich in gaultherin isolated from Gaultheria yunnanensis (FRANCH.) REHDER. Biol Pharm Bull. 2007;30:465-9 pubmed
    ..The observed effects of SDF are probably due to the presence of high content of salicylate derivatives (80%), including gaultherin, MSTG-A and MSTG-B...
  32. Sun S, Bao Z, Ma H, Zhang D, Zheng X. Singlet oxygen generation from the decomposition of alpha-linolenic acid hydroperoxide by cytochrome c and lactoperoxidase. Biochemistry. 2007;46:6668-73 pubmed
  33. Hu C, Wu J. [Progress in study of flavonoids from Annonaceae and biological activities of these compounds]. Zhongguo Zhong Yao Za Zhi. 2007;32:765-70 pubmed
    ..Due to the pharmacological interest of some of these compounds, chemical investigations on this topic have grown considerably in the decades. Here the biological activities of some of these flavonoids are also briefly discussed. ..
  34. An N, Zou Z, Tian Z, Luo X, Yang S, Xu L. Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Fitoterapia. 2008;79:27-31 pubmed
    ..Compound 4 showed moderate cytotoxicity against human tumor cell lines, HepG2, MCF-7 and SF-268, while no significant effect were found for compounds 1-3...
  35. Xu Q, Cheng B, Ye X, Zhai H. SmI(2)-mediated carbon-carbon bond fragmentation in alpha-aminomethyl malonates. Org Lett. 2009;11:4136-8 pubmed publisher
    ..The presence of the amino group is necessary for the success of the current transformation...
  36. Yao X, Chong H, Zhang C, Qiu Z, Qin B, Han R, et al. Structural basis of potent and broad HIV-1 fusion inhibitor CP32M. J Biol Chem. 2012;287:26618-29 pubmed publisher
    ..Therefore, our data present important information for developing novel HIV-1 fusion inhibitors for clinical use. ..
  37. Xiao S, Wang Q, Yu F, Peng Y, Yang M, Sollogoub M, et al. Conjugation of cyclodextrin with fullerene as a new class of HCV entry inhibitors. Bioorg Med Chem. 2012;20:5616-22 pubmed publisher
    ..17 ?M level...
  38. Luan Y, Zhang J, Zhan M, Wu J, Zhang J, He J. Highly efficient propionylation and butyralation of cellulose in an ionic liquid catalyzed by 4-dimethylminopyridine. Carbohydr Polym. 2013;92:307-11 pubmed publisher
    ..Therefore, this work provides a facile and highly efficient way for the synthesis of cellulose esters CP and CB...
  39. Tang J, Yu L, Fu H, Li C, Yang J, Zhou W, et al. Cytotoxic triterpenoid saponins from the stems of Gordonia longicarpa. Planta Med. 2013;79:353-60 pubmed publisher
    ..Compounds 5, 7, 8, 10, and 11 exhibited potent cytotoxic activity with IC50 values of 1.42-8.42 µM, while 6, 9, and 12 showed selective cytotoxic activity toward the tested cell lines...
  40. Deng W, Guo Z, Guo Y, Feng Z, Jiang Y, Chu F. Acryloylamino-salicylanilides as EGFR PTK inhibitors. Bioorg Med Chem Lett. 2006;16:469-72 pubmed
    ..Acrylamido moiety is incorporated to target the Cys-773 of EGFR specifically. Some of the obtained compounds exhibited good activity as EGFR inhibitors...
  41. Mingan W, Wenjun W, Jingbo Z, Zhiqing J, Wenming Z. Two new insecticidal sesquiterpene polyol esters from Celastrus angulatus. Nat Prod Res. 2006;20:653-8 pubmed
    ..Their chemical structures were elucidated mainly by analyses of the NMR and MS spectral data. Their insecticidal activities against Mythimna separate were demonstrated with the KD50 value of 68.5 and 215.8 microg g(-1), respectively. ..
  42. Chen L, Zhou Y, Dong J. [Three new flavonoid glycosides from Peperomia dindygulensis]. Yao Xue Xue Bao. 2007;42:183-6 pubmed
    ..Compounds I, II and III are all new compounds...
  43. Liu J, Feng Z, Xu J, Wang Y, Zhang P. Rare biscoumarins and a chlorogenic acid derivative from Erycibe obtusifolia. Phytochemistry. 2007;68:1775-80 pubmed
    ..Their structures were elucidated by spectroscopic methods. Among them, compounds (1) and (2) are rare carbon-carbon linked symmetrical biscoumarins...
  44. Qin W, Wang G, Lin R. [Studies on chemical constituents of Heterosmilax yunnanensis]. Zhong Yao Cai. 2007;30:959-61 pubmed
    ..To study the chemical constituents of Heterosmilax yunianensis...
  45. Zhao W, Zhao C, Gao L, Feng F, Gao W, Chen Z, et al. The novel inhibitory effect of Pangdahai on fatty acid synthase. IUBMB Life. 2008;60:185-94 pubmed publisher
    ..Three known flavonoid compounds were isolated from the extract and the structure-activity relationship was discussed...
  46. Wang F, Ma Z, Liu Y, Guo Y, Gu Z. New phenylethanoid glycosides from the fruits of forsythia suspense (thunb.) vahl. Molecules. 2009;14:1324-31 pubmed publisher
    ..Their structures were determined by spectroscopic and chemical methods...
  47. Bi D, Chai X, Song Y, Lei Y, Tu P. Novel bile acids from bear bile powder and bile of geese. Chem Pharm Bull (Tokyo). 2009;57:528-31 pubmed
  48. Guo H, Sun B, Gao H, Chen X, Liu S, Yao X, et al. Diketopiperazines from the Cordyceps-colonizing fungus Epicoccum nigrum. J Nat Prod. 2009;72:2115-9 pubmed publisher
    ..The absolute configurations of 3 and 5 were assigned using the modified Mosher (3) and Marfey's (5) methods, respectively. Compounds 3-5 showed inhibitory effects on HIV-1 replication in C8166 cells. ..
  49. Xu L, Xiao W, Peng Y, Liu H, Xiao P. [A novel lignan dimer from stems of Kadsura heteroclita]. Zhongguo Zhong Yao Za Zhi. 2010;35:1970-2 pubmed
    ..The structure was elucidated on the basis of nuclear magnetic resonance spectroscopic data. Heteroclitin R was a new compound as a lignan dimer obtained from Schisandraceae family for the first time...
  50. Yang Y, Jiang J, Qimei L, Yan X, Zhao J, Yuan H, et al. The fungicidal terpenoids and essential oil from Litsea cubeba in Tibet. Molecules. 2010;15:7075-82 pubmed publisher
    ..cucumeris and S. sclerotiorum, with IC?? values of 115.58 and 151.25 ?g/mL, repectively...
  51. Zhong L, Zhou L, Zhou Y, Chen Y, Sui P, Wang J, et al. Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides. Nat Prod Res. 2012;26:307-13 pubmed publisher
    ..The results obtained provide promising baseline information for the potential use of the extract and flavonoids from this plant as antimicrobial agents to help control plant diseases...
  52. Yang X, Qiang G, Zhang L, Zhu X, Wang S, Sun L, et al. Salvianolic acid A protects against vascular endothelial dysfunction in high-fat diet fed and streptozotocin-induced diabetic rats. J Asian Nat Prod Res. 2011;13:884-94 pubmed publisher
    ..Our data suggested that SalA could protect against vascular VED in diabetes, which might attribute to its suppressive effect on oxidative stress and AGEs-induced endothelial dysfunction. ..
  53. Gao C, Zhao L, Wang M. Stabilization of a reactive polynuclear silver carbide cluster through the encapsulation within a supramolecular cage. J Am Chem Soc. 2012;134:824-7 pubmed publisher
    ..The multinuclear silver carbide cluster aggregate in 3 is encapsulated by two Py6 ligands through both metal-ligand coordination and cation-? interactions, spotlighting a new synthetic strategy for supramolecular capsules...
  54. Li Y, Chen Z, Feng Z, Yang Y, Jiang J, Zhang P. Hepatoprotective glycosides from Leonurus japonicus Houtt. Carbohydr Res. 2012;348:42-6 pubmed publisher
    ..When tested in in vitro assays, compounds 1, 2, 4, and 6 exhibited potent hepatoprotective activity against d-galactosamine-induced toxicity in HL-7702 cells at concentration of 1×10(-5) M...
  55. Su W, Zhou Y, Ma Y, Wang L, Zhang Z, Rui C, et al. N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships. J Agric Food Chem. 2012;60:5028-34 pubmed publisher
    ..Simple synthesis, low cost, and good insecticidal activity have made this series of compounds become very promising candidates for future commercial pesticides. ..
  56. Shao J, Huang C, Kalyanaraman B, Zhu B. Potent methyl oxidation of 5-methyl-2'-deoxycytidine by halogenated quinoid carcinogens and hydrogen peroxide via a metal-independent mechanism. Free Radic Biol Med. 2013;60:177-82 pubmed publisher
    ..This is the first report that halogenated quinoid carcinogens and H2O2 can induce potent methyl oxidation of 5mdC via a metal-independent mechanism, which may partly explain their potential carcinogenicity. ..
  57. Zhang G, Zhuang P, Wang X, Yu S, Ma S, Qu J, et al. Sesquiterpenes from the roots of Illicium jiadifengpi. Planta Med. 2013;79:1056-62 pubmed publisher
    ..Compounds 4, 6, 7, 14, and 23 showed moderate antiviral activities against Coxsackie virus B3, and all compounds were inactive when evaluated for their cytotoxic activities against five human tumor cell lines and neuroprotection. ..
  58. Zheng B, Jia T, Walsh P. Palladium-catalyzed direct intermolecular ?-arylation of amides with aryl chlorides. Org Lett. 2013;15:4190-3 pubmed publisher
    ..Chemoselectivities up to 10:1 in the mono- and diarylation of acetamides were achieved by careful selection of bases, solvents, and stoichiometry. Bis-arylated amides were prepared in up to 95% yield. ..
  59. Zhu J, Nakagawa S, Chen W, Adachi I, Jia Y, Hu X, et al. Synthesis of eight stereoisomers of pochonicine: nanomolar inhibition of ?-N-acetylhexosaminidases. J Org Chem. 2013;78:10298-309 pubmed publisher
    ..3-epi-Pochonicine (2L) was found to be a potent and selective inhibitor of ?-l-rhamnosidase. None of the compounds showed any inhibition of ?-GalNAcase. ..
  60. Luo Z, Zhu H, Lin X, Chu T, Luo R, Wang Y, et al. Synthesis and radiolabeling of (64)Cu-labeled 2-nitroimidazole derivative (64)Cu-BMS2P2 for hypoxia imaging. Bioorg Med Chem Lett. 2016;26:1397-400 pubmed publisher
    ..These results suggest that (64)Cu-BMS2P2 is a promising candidate for PET hypoxia imaging and worthy of further investigations in dynamic hypoxia imaging. ..
  61. Wu L, Liang W, Chen W, Li S, Cui Y, Qi Q, et al. Screening and Analysis of the Marker Components in Ganoderma lucidum by HPLC and HPLC-MSn with the Aid of Chemometrics. Molecules. 2017;22: pubmed publisher
    ..lucidum. The results proved that fingerprints combined with chemometrics are a simple, rapid and effective method for the quality control of G. lucidum. ..
  62. Ye M, Guo D, Ye G, Huang C. Analysis of homoisoflavonoids in Ophiopogon japonicus by HPLC-DAD-ESI-MSn. J Am Soc Mass Spectrom. 2005;16:234-43 pubmed
    ..3% acetic acid gradient. A total of 18 homoisoflavonoids, including seven new minor constituents, were identified or tentatively characterized based on the UV spectra and tandem mass spectra of the HPLC peaks. ..
  63. Xue P, Lu X, Wang B, Liang H, Zhao Y. [The megastigman glycosides from herb of Potentilla multifida]. Zhongguo Zhong Yao Za Zhi. 2005;30:983-6 pubmed
    ..To investigate the chemical constituents of Potentilla multifida...
  64. Zhao Q, Zhao Y, Wang K. [Alkaloids from the root of Lindera angustifolia]. Yao Xue Xue Bao. 2005;40:931-4 pubmed
    ..The structure of VII was further identified by semi-synthesis with I as starting material. All compounds were obtained from this plant for the first time and compound VII was found as a naturally occurring compound for the first time. ..
  65. Cheng Z, Li Y. What is responsible for the initiating chemistry of iron-mediated lipid peroxidation: an update. Chem Rev. 2007;107:748-66 pubmed
  66. Sun J, Yang J, Zhang H. Two new flavanone glycosides of Jasminum lanceolarium and their anti-oxidant activities. Chem Pharm Bull (Tokyo). 2007;55:474-6 pubmed
    ..The isolated compounds were screened for their in vitro antioxidant activity through DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging assay. Compounds 2 demonstrated significant radical scavenging activity...
  67. Yang G, Zhao Y, Li M, Zhu Z, Zhuang Q. Study on chiral resolution of three beta-blockers by affinity electrokinetic chromatography. Talanta. 2008;75:222-6 pubmed publisher
    ..Based on linear correlation coefficient, it can be concluded that the binding ratio of pindolol (oxprenolol) combining with BSA is 1:1, and that the binding number of propranolol interacting with BSA deviates one...
  68. Tan Y, Yan R, Wang H, Chen R, Yu D. Wittiorumins A - F, antioxidant diels-alder-type adducts from Morus wittiorum. Planta Med. 2009;75:249-55 pubmed publisher
    ..0 %, 82.0 %, and 82.0 %, respectively, at a concentration of 10 ( - 5) M. ..
  69. Han B, Wang P, Zhu G, Zhang L, Qu F, Deng Y, et al. Microchip free flow isoelectric focusing for protein prefractionation using monolith with immobilized pH gradient. J Sep Sci. 2009;32:1211-5 pubmed publisher
  70. Zhang X, Chen T, Chen Q, Wang L, Wan L. Self-assembly and aggregation of melamine and melamine-uric/cyanuric acid investigated by STM and AFM on solid surfaces. Phys Chem Chem Phys. 2009;11:7708-12 pubmed
    ..The size of the cluster is dependent on the molecular concentration. The results provide important information for the self-assembly of triazine compounds and are significant in the study of kidney disease related to melamine. ..
  71. Jia J, Wang K, Shi W, Chen S, Li X, Ma H. Rhodamine B piperazinoacetohydrazine: a water-soluble spectroscopic reagent for pyruvic acid labeling. Chemistry. 2010;16:6638-43 pubmed publisher
  72. Duan C, Ma X, Jiang Y, Liu J, Tu P. Two new furostanol glycosides from the fibrous root of Ophiopogon japonicus (Thunb.) Ker-Gawl. J Asian Nat Prod Res. 2010;12:745-51 pubmed publisher
  73. Tian D, Zhang X, Wang X, Zhai J, Jiang L. Micro/nanoscale hierarchical structured ZnO mesh film for separation of water and oil. Phys Chem Chem Phys. 2011;13:14606-10 pubmed publisher
    ..This work provides an alternative to current separation meshes and is promising in various important applications such as separation and filtration, lab-on-a-chip devices and micro/nanofluidic devices. ..
  74. Mu L, Wei N, Liu P. Cytotoxic triterpenoid saponins from Ardisia gigantifolia. Planta Med. 2012;78:617-21 pubmed publisher
    ..9-4.8 µm...
  75. Hu L, Yan S, Luo Z, Han X, Wang Y, Wang Z, et al. Design, practical synthesis, and biological evaluation of novel 6-(pyrazolylmethyl)-4-quinoline-3-carboxylic acid derivatives as HIV-1 integrase inhibitors. Molecules. 2012;17:10652-66 pubmed publisher
    ..The structures of all new compounds were confirmed by 1H-NMR, 13C-NMR and ESI (or HRMS) spectra. Detailed synthetic protocols and the anti-IN activity studies are also presented. ..
  76. Jiao L, Yu Z. Vinylcyclopropane derivatives in transition-metal-catalyzed cycloadditions for the synthesis of carbocyclic compounds. J Org Chem. 2013;78:6842-8 pubmed publisher
    ..A tabular summary of applications of the VCP cycloadditions in natural product synthesis is also presented. ..
  77. Zhou S, Jia Y. Total synthesis of (-)-goniomitine. Org Lett. 2014;16:3416-8 pubmed publisher
    ..Notably, the high degree of convergence of this strategy makes it particularly amenable to the total synthesis of other aspidosperma family natural products. ..
  78. Zhao S, Dai J, Hu M, Liu C, Meng R, Liu X, et al. Photo-induced coupling reactions of tetrazoles with carboxylic acids in aqueous solution: application in protein labelling. Chem Commun (Camb). 2016;52:4702-5 pubmed publisher
  79. Wang G, Yan H, Hou Q, Lu Y, Gong N, Lin R. [Chemical constituents from Alyxia sinensis (II)]. Zhongguo Zhong Yao Za Zhi. 2002;27:199-201 pubmed
    ..These compounds were found from the plant for the first time, and compound 20,21,23-25 were found from Alyxiae genis for the first time, and compound 18 is firstly been isolated from natural source. ..
  80. Du S, Wang M, Zhu W, Qin Z. A new fungicidal lactone from Xylocarpus granatum (Meliaceae). Nat Prod Res. 2009;23:1316-21 pubmed publisher
    ..At a concentration of 20 microg mL(-1), the new lactone gave a 67.4% inhibition rate against wheat powdery mildew...
  81. Guo N, Zhao Y, Fang W. Biotransformation of 3-oxo-oleanolic acid by Absidia glauca. Planta Med. 2010;76:1904-7 pubmed publisher
  82. Tian T, Zhong W, Meng S, Meng X, Li Z. Hypervalent iodine mediated para-selective fluorination of anilides. J Org Chem. 2013;78:728-32 pubmed publisher
    ..Because of its operational safety and the use of readily available reagents, this new procedure provides facile access to a variety of para-fluorinated anilides. ..
  83. Li C, Sun Y, Sun Y. [Chemical composition of fructus Liquidambaris--lulutong]. Yao Xue Xue Bao. 2002;37:263-6 pubmed
    ..To study the chemical composition in the fruits of Liquidambar formana Hance...
  84. Niu F, Cui Z, Li Q, Chang H, Jiang Y, Qiao L, et al. Complete assignments of 1H and 13C NMR spectral data for a novel diterpenoid from Semiaquilegia adoxoides. Magn Reson Chem. 2006;44:724-6 pubmed
    ..Its chemical structure was established as 3beta, 11- dihydroxy-12-O-beta-D-glucopyranosyl-8,11,13-abietatrien-6-one through spectroscopic techniques and chemical analysis...
  85. Liu H, Zhang Y, Meng L, Qin P, Wei J, Jia W, et al. Non-gel-based dual 18O labeling quantitative proteomics strategy. Anal Chem. 2007;79:7700-7 pubmed
    ..The combination of chemical and proteolytic (18)O labeling improved the confidence of the quantitation results. ..
  86. Zhang L, Guo Y, Tu G, Shi R, Qin W, Ba Y, et al. [A novel triterpenoid saponin from Prunella vulgaris]. Yao Xue Xue Bao. 2008;43:169-72 pubmed
    ..Compound I is a novel triterpenoid saponin and named as prunelloside A. Compound II was obtained for the first time from the Prunella genus...
  87. Li H, Ye M, Guo H, Tian Y, Zhang J, Zhou J, et al. Biotransformation of 20(S)-protopanaxadiol by Mucor spinosus. Phytochemistry. 2009;70:1416-20 pubmed publisher
    ..These biocatalytic reactions may be difficult for chemical synthesis. The biotransformed products showed weak in vitro cytotoxic activities. ..
  88. Lu J, Cheng C, Zhao X, Liu Q, Yang P, Wang Y, et al. PEG-scutellarin prodrugs: synthesis, water solubility and protective effect on cerebral ischemia/reperfusion injury. Eur J Med Chem. 2010;45:1731-8 pubmed publisher
    ..2% to 12.2% (33.3% for the control) and decrease the neurological deficit score from 2.77 to 1.32 (2.85 for the control). The half-life (18.62 min) of the prodrug 7e was significantly longer than that of scutellarin (3.03 min). ..
  89. Li S, Shi Y, Shang X, Cui B, Yuan Y, Chen X, et al. Triterpenoids from the roots of Pterospermum heterophyllum Hance. J Asian Nat Prod Res. 2009;11:652-7 pubmed publisher
    ..21, 0.55, 0.40, 0.59, and 0.34 microM, respectively. However, the other compounds were inactive (IC(50)>10 microM)...
  90. Liu X, Ren B, Chen M, Wang H, Kokare C, Zhou X, et al. Production and characterization of a group of bioemulsifiers from the marine Bacillus velezensis strain H3. Appl Microbiol Biotechnol. 2010;87:1881-93 pubmed publisher
    ..Thus B. velezensis H3 is an alternative surfactin producer with potential application as an industrial strain for the lipopeptide production...
  91. Feng Z, Wang Y, Guo Z, Chu F, Sun P. The synthesis of puerarin derivatives and their protective effect on the myocardial ischemia and reperfusion injury. J Asian Nat Prod Res. 2010;12:843-50 pubmed publisher
  92. Xie B, Shang M, Wang X, Cai S, Lee K. [A new aristolochic acid derivative from Asarum himalaicum]. Yao Xue Xue Bao. 2011;46:188-92 pubmed
    ..Since the kidney toxicity of aristolochic acids and aristololactams has been reported, the result of this investigation suggests that it should be cautioned to use A. himalaicum as a medicine. ..