Genomes and Genes
Experts and Doctors on micrornas in Jiangsu, China
Locale: Jiangsu, China
- Wang N, Zhou Y, Jiang L, Li D, Yang J, Zhang C, et al. Urinary microRNA-10a and microRNA-30d serve as novel, sensitive and specific biomarkers for kidney injury. PLoS ONE. 2012;7:e51140 pubmed publisher..In conclusion, the present study collectively demonstrates that urinary miR-10a and miR-30d represent a novel noninvasive, sensitive, specific and potentially high-throughput method for detecting renal injury. ..
- Li L, Hou D, Guo Y, Yang J, Liu Y, Zhang C, et al. Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes. J Immunol. 2011;186:2552-60 pubmed publisher..Our findings define a new role for miR-214-targeting PTEN in AGE-induced monocyte survival. ..
- Xu Y, Xi Q, Ge W, Zhang X. Identification of serum microRNA-21 as a biomarker for early detection and prognosis in human epithelial ovarian cancer. Asian Pac J Cancer Prev. 2013;14:1057-60 pubmed..These findings indicate that serum miR-21 may serve as a novel diagnostic and prognostic marker, and be used as a therapeutic target for the treatment of EOC. ..
- Xu L, Xiang J, Shen J, Zou X, Zhai S, Yin Y, et al. Oncogenic MicroRNA-27a is a target for genistein in ovarian cancer cells. Anticancer Agents Med Chem. 2013;13:1126-32 pubmed
- Xu S, Yi X, Zhou W, Cheng W, Ge J, Zhang Z. Downregulation of miR-129 in peripheral blood mononuclear cells is a diagnostic and prognostic biomarker in prostate cancer. Int J Clin Exp Pathol. 2015;8:14335-44 pubmed..Overexpression of miR-129 exerts tumor suppressive functions and abrogates prostate cancer growth. ..
- Li H, Hui L, Xu W, Shen H, Chen Q, Long L, et al. Triptolide modulates the sensitivity of K562/A02 cells to adriamycin by regulating miR-21 expression. Pharm Biol. 2012;50:1233-40 pubmed publisher..Our findings indicated that triptolide modulates the sensitivity of K562/A02 cells to adriamycin by regulating miR-21 expression. Triptolide inhibited miR-21 expression and enhanced PTEN levels in K562/A02 cells. ..
- Wu J, He D, Yue B, Zhang C, Fang X, Chen H. miR-101-1 expression pattern in Qinchuan cattle and its role in the regulation of cell differentiation. Gene. 2017;636:64-69 pubmed publisher..The results show that amyloid precursor protein (APP) is the target gene of miR-101-1. Therefore, our results shed light on miR-101-1 in the regulation of the skeletal muscle development. ..