Experts and Doctors on estradiol in Chongqing, Chongqing Shi, China


Locale: Chongqing, Chongqing Shi, China
Topic: estradiol

Top Publications

  1. Zhao X, Huang L, Yin Y, Fang Y, Zhao J, Chen J. Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3K-dependent pathways. Microvasc Res. 2008;75:45-52 pubmed
    ..These results suggest that estrogen induces EPCs migration and proliferation via ERs and PI3K pathway which provided a novel insight and treatment strategy of vascular biology. ..
  2. Wei J, Yu L, Sun L, Zhang X, Li M, Qi W, et al. Molecular cloning and expression analysis of Foxp3 from Nile tilapia. Vet Immunol Immunopathol. 2013;155:48-56 pubmed publisher
    ..This work will help future investigations into Tr cells and extend our understanding of interactions between sex hormones and immune related molecules in teleosts. ..
  3. Jiang D, Chen J, Fan Z, Tan D, Zhao J, Shi H, et al. CRISPR/Cas9-induced disruption of wt1a and wt1b reveals their different roles in kidney and gonad development in Nile tilapia. Dev Biol. 2017;428:63-73 pubmed publisher
    ..The XY wt1b-/- fish had normal serum estradiol-17? and 11-ketotestosterone levels and remained fertile. These results suggest that Wt1a and Wt1b have different functions in the kidneys and gonads of tilapia. ..
  4. Lan Y, Liu J, Cheng H, Zou S, Gan X. [Expressions of SHP and CYP7A1 in pregnant rats with intrahepatic cholestasis]. Zhonghua Gan Zang Bing Za Zhi. 2008;16:453-6 pubmed
    ..01)]. Estrogen induces ICP in rats. The mRNA and protein expressions of SHP and CYP7A1 in livers of the ICP rats were increased, which causes more bile acids to be synthesized. This may be one of the mechanisms of ICP. ..
  5. Wang D, Zhou L, Kobayashi T, Matsuda M, Shibata Y, Sakai F, et al. Doublesex- and Mab-3-related transcription factor-1 repression of aromatase transcription, a possible mechanism favoring the male pathway in tilapia. Endocrinology. 2010;151:1331-40 pubmed publisher
    ..Our results indicate that aromatase is one of the targets of Dmrt1. Dmrt1 suppresses the female pathway by repressing aromatase gene transcription and estrogen production in the gonads of tilapia and possibly other vertebrates...
  6. Li A, Wang Y, Dong W, Xu X. [Inhibitory effect on estrogen production and its influence on invasive ability of human endometrial cells of endometriosis by medicated serum of SLW]. Zhongguo Zhong Yao Za Zhi. 2010;35:1607-11 pubmed
    ..SLW could decrease the secretion of E2 so as to inhibit the invasion of the eutopic endometrial cells of endometriosis. ..
  7. Xu C, Chen J, Qiu Z, Zhao Q, Luo J, Yang L, et al. Ovotoxicity and PPAR-mediated aromatase downregulation in female Sprague-Dawley rats following combined oral exposure to benzo[a]pyrene and di-(2-ethylhexyl) phthalate. Toxicol Lett. 2010;199:323-32 pubmed publisher
    ..In addition, based on qualitative assessment of the combined toxicity, no interaction effects were observed following combined B[a]P and DEHP administration...
  8. Hu R, Sun H, Zhang Q, Chen J, Wu N, Meng H, et al. G-protein coupled estrogen receptor 1 mediated estrogenic neuroprotection against spinal cord injury. Crit Care Med. 2012;40:3230-7 pubmed publisher
  9. Zhou L, Charkraborty T, Yu X, Wu L, Liu G, Mohapatra S, et al. R-spondins are involved in the ovarian differentiation in a teleost, medaka (Oryzias latipes). BMC Dev Biol. 2012;12:36 pubmed publisher
    ..These results suggest that the Rspo-activating signaling pathway is involved in the ovarian differentiation and maintenance in medaka...

More Information


  1. Liu C, Duan W, Li R, Xu S, Zhang L, Chen C, et al. Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity. Cell Death Dis. 2013;4:e676 pubmed publisher
    ..These rodent data support the growing association between BPA exposure and the rapid increase in the incidence of male reproductive disorders. ..
  2. Zhang Q, Li Y, Liu Z, Chen Q. Reproductive toxicity of inorganic mercury exposure in adult zebrafish: Histological damage, oxidative stress, and alterations of sex hormone and gene expression in the hypothalamic-pituitary-gonadal axis. Aquat Toxicol. 2016;177:417-24 pubmed publisher
  3. Huang X, Jiao B, Fung C, Zhang Y, Ho W, Chan C, et al. The presence of two distinct prolactin receptors in seabream with different tissue distribution patterns, signal transduction pathways and regulation of gene expression by steroid hormones. J Endocrinol. 2007;194:373-92 pubmed
    ..The sbPRLR1 gene promoter activity was activated by estradiol and cortisol, but not by testosterone. In contrast, the sbPRLR2 gene promoter activity was inhibited by estradiol, cortisol, and testosterone. ..
  4. Chen L, Qiu J, Yang C, Yang X, Chen X, Jiang J, et al. Identification of a novel estrogen receptor beta1 binding partner, inhibitor of differentiation-1, and role of ERbeta1 in human breast cancer cells. Cancer Lett. 2009;278:210-219 pubmed publisher
    ..Taken together, our study demonstrates a novel ERbeta1 binding partner, Id1, and a mechanism by which ERbeta1 inhibits breast cancer cell growth through binding with Id1 and upregulating p21 gene expression. ..
  5. Zhang C, Zhao J, Deng H. 17?-estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells. Mol Cell Biochem. 2013;379:201-11 pubmed publisher
  6. Bian C, Zhao Y, Guo Q, Xiong Y, Cai W, Zhang J. Aromatase inhibitor letrozole downregulates steroid receptor coactivator-1 in specific brain regions that primarily related to memory, neuroendocrine and integration. J Steroid Biochem Mol Biol. 2014;141:37-43 pubmed publisher
    ..Furthermore, these potential central adverse effects of letrozole should be taken into serious considerations. ..
  7. Zhao Y, He L, Zhang Y, Zhao J, Liu Z, Xing F, et al. Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice. J Steroid Biochem Mol Biol. 2017;174:96-113 pubmed publisher