Experts and Doctors on kupffer cells in Hefei, Anhui Sheng, China
Locale: Hefei, Anhui Sheng, China
Topic: kupffer cells
Jiang W, Sun R, Zhou R, Wei H, Tian Z. TLR-9 activation aggravates concanavalin A-induced hepatitis via promoting accumulation and activation of liver CD4+ NKT cells. J Immunol. 2009;182:3768-74 pubmed publisher
..Collectively, our data demonstrate that TLR9 stimulation prefers to promote the accumulation and activation of hepatic CD4(+) NKT cells and suggest that TLR9 signaling might be involved in the pathogenesis of human hepatitis. ..
Tang X, Yang J, Li J. Accelerative effect of leflunomide on recovery from hepatic fibrosis involves TRAIL-mediated hepatic stellate cell apoptosis. Life Sci. 2009;84:552-7 pubmed
Chen X, Sun L, Guo F, Wang F, Liu S, Liang X, et al
. High-mobility group box-1 induces proinflammatory cytokines production of Kupffer cells through TLRs-dependent signaling pathway after burn injury. PLoS ONE. 2012;7:e50668 pubmed publisher
..These results indicate that HMGB1 induces proinflammatory cytokines production of KCs after sever burn injury, and this process might be largely dependent on TLRs-dependent MAPKs/NF-?B signal pathway...
Deng Y, Ma H, Tsuneyama K, Yang W, Wang Y, Lu F, et al
. STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib. J Autoimmun. 2013;46:25-34 pubmed publisher
Li Y, Cao G, Zheng X, Wang J, Wei H, Tian Z, et al
. CRACC-CRACC interaction between Kupffer and NK cells contributes to poly I:C/D-GalN induced hepatitis. PLoS ONE. 2013;8:e76681 pubmed publisher
..Collectively, our findings suggest that CRACC-CRACC interaction between NK cells and resident Kupffer cells contributes to Poly I:C/D-GalN-induced fulminant hepatitis. ..
Bi J, Zhang Q, Liang D, Xiong L, Wei H, Sun R, et al
. T-cell Ig and ITIM domain regulates natural killer cell activation in murine acute viral hepatitis. Hepatology. 2014;59:1715-25 pubmed publisher
Wu X, Yang Y, Li W, Cheng Y, Li X, Huang C, et al
. Telomerase reverse transcriptase acts in a feedback loop with NF-ÎºB pathway to regulate macrophage polarization in alcoholic liver disease. Sci Rep. 2016;6:18685 pubmed publisher
Hou X, Zhou R, Wei H, Sun R, Tian Z. NKG2D-retinoic acid early inducible-1 recognition between natural killer cells and Kupffer cells in a novel murine natural killer cell-dependent fulminant hepatitis. Hepatology. 2009;49:940-9 pubmed publisher
..These results provide the first in vivo evidence that NKG2D/ligand interaction is involved in the synergic effects of NK cells and Kupffer cells on acute liver injury. ..
Chu D, DU M, Hu X, Wu Q, Shen J. Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosis through inhibiting alternative activation of macrophages. Parasitology. 2011;138:1259-71 pubmed publisher
..PAE might be a promising prophylactic agent for hepatic granuloma and fibrosis of schistosomiasis japonica...