Experts and Doctors on calcium in Hefei, Anhui Sheng, China


Locale: Hefei, Anhui Sheng, China
Topic: calcium

Top Publications

  1. You W, Zhou T, Ma Z, Liang Q, Xiao C, Tang X, et al. Ophiopogonin D maintains Ca2+ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stress. Acta Pharmacol Sin. 2016;37:368-81 pubmed publisher
    ..OPD is a novel CYP2J3 inducer that may offer a therapeutic benefit in treatment of cardiovascular diseases related to disturbance of Ca(2+) homeostasis and ER stress. ..
  2. Li C, Liang D, Li J, Duan Y, Li H, Yang Y, et al. Unravelling mitochondrial retrograde regulation in the abiotic stress induction of rice ALTERNATIVE OXIDASE 1 genes. Plant Cell Environ. 2013;36:775-88 pubmed publisher
    ..Therefore, our findings demonstrate that abiotic stress initiates the MRR on OsAOX1a/b and that mitochondrial O2·(-) is involved in the process. ..
  3. Zhang X, Gao H, Yang T, Wu H, Wang Y, Zhang Z, et al. Anion Channel Inhibitor NPPB-Inhibited Fluoride Accumulation in Tea Plant (Camellia sinensis) Is Related to the Regulation of Ca²⁺, CaM and Depolarization of Plasma Membrane Potential. Int J Mol Sci. 2016;17: pubmed publisher
    ..Overall, our results suggest that regulation of Ca(2+)-CaM and plasma membrane potential depolarization are involved in NPPB-inhibited F accumulation in tea plants. ..
  4. Li Y, Wu L, Legendre P, Xu T. Asymmetric cross-inhibition between GABAA and glycine receptors in rat spinal dorsal horn neurons. J Biol Chem. 2003;278:38637-45 pubmed
  5. Du J, Wang X, Li J, Guo J, Liu L, Yan D, et al. Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging. Sci Rep. 2016;6:22780 pubmed publisher
    ..We concluded that impaired TRPV4-mediated Ca(2+) signaling causes endothelial dysfunction and that TRPV4 is a potential target for clinical treatment of age-related vascular system diseases. ..
  6. Hu W, Chen F, Yuan F, Zhang T, Wu F, Rong C, et al. Blockade of acid-sensing ion channels protects articular chondrocytes from acid-induced apoptotic injury. Inflamm Res. 2012;61:327-35 pubmed publisher
    ..The data presented in this study provided some experimental evidence that blocking ASICs could protect acid-induced apoptotic injury to chondrocytes. ..
  7. Shen B, Zhu J, Zhang J, Jiang F, Wang Z, Zhang Y, et al. Attenuated mesangial cell proliferation related to store-operated Ca2+ entry in aged rat: the role of STIM 1 and Orai 1. Age (Dordr). 2013;35:2193-202 pubmed publisher
    ..We conclude that the attenuation of GMCs proliferation can be attributed to the decreased SOCE partially caused by reduced expression of STIM 1 and Orai 1. ..
  8. Wang P, Wu Y, Li Y, Zheng J, Tang J. A novel RING finger E3 ligase RNF186 regulate ER stress-mediated apoptosis through interaction with BNip1. Cell Signal. 2013;25:2320-33 pubmed publisher
    ..These results collectively indicate that BNip1 functions as a downstream modulator of RNF186 to direct ER stress-associated apoptotic signaling. Our study might reveal a novel E3 ligase-mediated mechanism for modulating ER stress. ..
  9. Xu T, Gong N, Xu T. Divalent cation modulation of a-type potassium channels in acutely dissociated central neurons from wide-type and mutant Drosophila. J Neurogenet. 2005;19:87-107 pubmed

More Information


  1. Sun M, Fan H, Ma H, Zhu Q. [Protective effect of total glucosides of Picrorhiza scrophulariiflora against oxidative stress in glomerular mesangial cells induced by high glucose]. Yao Xue Xue Bao. 2007;42:381-5 pubmed
    ..Therefore we conclude that TGP could protect mesangial cells against oxidative stress induced by high glucose...
  2. Tang M, Xing T, Zeng J, Wang H, Li C, Yin S, et al. Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ Health Perspect. 2008;116:915-22 pubmed publisher
    ..Meanwhile the interference of QDs with voltage-gated sodium channel (VGSC) current (I(Na)) may lead to changes in electrical activity and worsen neurotoxicologic damage...
  3. Tang Q, Han R, Xiao H, Shen J, Luo Q, Li J. Neuroprotective effects of tanshinone IIA and/or tetramethylpyrazine in cerebral ischemic injury in vivo and in vitro. Brain Res. 2012;1488:81-91 pubmed publisher
    ..The PI3K/AKT signaling pathway may be involved in the neuroprotective mechanism of Tan IIA on primary cortical neurons. ..
  4. Wen L, Wen Y, Ke G, Sun S, Dong K, Wang L, et al. TRPV4 regulates migration and tube formation of human retinal capillary endothelial cells. BMC Ophthalmol. 2018;18:38 pubmed publisher
    ..TRPV4 is essential for HRCEC migration and tube formation, and maybe a potential therapeutic target for retinal vascular diseases. ..
  5. Xu X, Liu Q, Yu H, Xie Y. Ca(II)- and Tb(III)-induced stabilization and refolding of anticoagulation factor I from the venom of Agkistrodon acutus. Protein Sci. 2002;11:944-56 pubmed
  6. Li Q, Cui M, Yang F, Li N, Jiang B, Yu Z, et al. A cullin 4B-RING E3 ligase complex fine-tunes pancreatic ? cell paracrine interactions. J Clin Invest. 2017;127:2631-2646 pubmed publisher
    ..Our results reveal an epigenetic regulatory mechanism of ? cell paracrine interactions in which CRL4B-PRC2 complexes, Cav1.2, and AC6 expression fine-tune somatostatin secretion and facilitate glucose homeostasis in pancreatic islets. ..
  7. Wang X, Ma Z, Fu Z, Gao S, Yang L, Jin Y, et al. Hydroxysafflor Yellow A Protects Neurons From Excitotoxic Death through Inhibition of NMDARs. ASN Neuro. 2016;8: pubmed publisher
    ..This novel finding indicates that HSYA may be a promising pharmacological candidate for the treatment of brain ischemia. ..
  8. Yang J, Cao Y, Wang R, Fei Y, Zhang H, Feng P, et al. Anti-resorptive effect of pilose antler blood (Cervus nippon Temminck) in ovariectomized rats. Indian J Exp Biol. 2010;48:554-8 pubmed
    ..These results suggested that administration of pilose antler blood was effective in alleviating osteoporosis in ovariectomized rats. ..
  9. Yuan F, Chen F, Lu W, Li X, Wu F, Li J, et al. Acid-sensing ion channel 1a mediates acid-induced increases in intracellular calcium in rat articular chondrocytes. Mol Cell Biochem. 2010;340:153-9 pubmed publisher
    ..These findings show that increased [Ca(2+)]i, mediated via ASIC1a, might contribute to acidosis-induced articular chondrocyte injury. ..
  10. Wei S, Liu Y, Qu H, Cao J, Ye H. [Effects of nitrogen and calcium on polyphenol oxidase, peroxidase and leaf spot in carnation]. Ying Yong Sheng Tai Xue Bao. 2002;13:126-7 pubmed
    ..The result showed that the nutrition state [NO3- (0.024%-0.025%), Ca2+ (0.022%-0.0342%)] was helpful to keep higher activity of POD and PPO and enhance the carnation's resistance to the germs...
  11. Li M, Wu D, Wang J. Effects of volume-activated chloride channels on the invasion and migration of human endometrial cancer cells. Eur J Gynaecol Oncol. 2013;34:60-4 pubmed
    ..These data intensely suggest that VACC in endometrial cancer may facilitate tumor invasion and migration, presumably through inducing RVD and mediating [Ca2+]i increase. ..
  12. Wu H, Xu X, Zhang L, Shen D, Peng L, Zhang Y, et al. Mg(II)-induced binding of factor IX-binding protein from the venom of Agkistrodon Halys Pallas with factor Xa. Toxicon. 2010;55:1358-64 pubmed publisher
    ..Both Ca2+ and Zn2+ ions fail to induce the binding between apo-AHP IX-bp and FXa. The abundant Mg2+ ions in blood play an important role in the anticoagulation of AHP IX-bp...
  13. Tang M, Wang M, Xing T, Zeng J, Wang H, Ruan D. Mechanisms of unmodified CdSe quantum dot-induced elevation of cytoplasmic calcium levels in primary cultures of rat hippocampal neurons. Biomaterials. 2008;29:4383-91 pubmed publisher
    ..Our results imply that more research on the biocompatibility and biosafety of QD is both warranted and necessary...