Experts and Doctors on animals in Saskatoon, Saskatchewan, Canada


Locale: Saskatoon, Saskatchewan, Canada
Topic: animals

Top Publications

  1. Pato M, Kerc E, Lye S. Phosphorylation and partial sequence of pregnant sheep myometrium myosin light chain kinase. Mol Cell Biochem. 1995;149-150:59-69 pubmed
  2. Hemmings S, Spafford D. Neonatal STZ model of type II diabetes mellitus in the Fischer 344 rat: characteristics and assessment of the status of the hepatic adrenergic receptors. Int J Biochem Cell Biol. 2000;32:905-19 pubmed
    ..We propose that the diabetes-evoked decrease in the dominant adrenergic receptor-effector system through which catecholamines act may be the cellular expression of defective glucocounterregulation in the diabetic state. ..
  3. Cao K, Tang G, Hu D, Wang R. Molecular basis of ATP-sensitive K+ channels in rat vascular smooth muscles. Biochem Biophys Res Commun. 2002;296:463-9 pubmed
    ..Our results for the first time reported the expression of four K(ATP) subunits in same vascular tissues, unmasking the diversity of native K(ATP) channels in vascular SMCs. ..
  4. Rajala R, Kakkar R, Kanthan R, Radhi J, Wang X, Wang R, et al. Altered expression and localization of N-myristoyltransferase in experimentally induced rat model of ischemia-reperfusion. J Cell Biochem. 2002;86:509-19 pubmed
    ..This is the first study demonstrating the expression and alteration of NMT localization in cardiac ischemia and pertaining to a possible role of co-translational modification of proteins in cardiac functions and injury. ..
  5. Gomis S, Babiuk L, Godson D, Allan B, Thrush T, Townsend H, et al. Protection of chickens against Escherichia coli infections by DNA containing CpG motifs. Infect Immun. 2003;71:857-63 pubmed
    ..This is the first time that CpG-ODN((2007)) has been demonstrated to have an immunoprotective effect against an extracellular bacterial infection in any food animal species. ..
  6. Rawlings N, Simko E, Bebchuk T, Caldwell S, Singh B. Localization of integrin alpha(v)beta3 and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in cutaneous and oral melanomas of dog. Histol Histopathol. 2003;18:819-26 pubmed publisher
    ..These data demonstrate expression and co-localization of integrin alpha(v)beta3 and VEGFR-2 in cutaneous and oral melanomas of dogs. ..
  7. Boutilier P, Carr A, Schulman R. Leptospirosis in dogs: a serologic survey and case series 1996 to 2001. Vet Ther. 2003;4:387-96 pubmed
    ..In 12 cases, the predominant serovar was L. grippotyphosa; titers to L. grippotyphosa and L. bratislava were equal in magnitude in three cases. ..
  8. Ghosh M, Hanna S, Wang R, McNeill J. Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. J Cardiovasc Pharmacol. 2004;44:525-31 pubmed
    ..These findings suggest that the function of KATP channels is impaired in smooth muscle cells from aorta of DOCA-salt hypertensive rats, which may contribute to the impaired vasodilatation and spontaneous tone observed in these rats. ..
  9. Wu Q, Chen Y, Kulshreshtha V, Tikoo S. Characterization and nuclear localization of the fiber protein encoded by the late region 7 of bovine adenovirus type 3. Arch Virol. 2004;149:1783-99 pubmed
    ..The recombinant BAdV-3 expressing mutant fiber containing 16EAEE19 instead of 16KAKR19 was unable to replicate efficiently in Madin-Darby bovine kidney cells, suggesting that the NLS of fiber carries out important in vivo functions. ..

More Information

Publications442 found, 100 shown here

  1. Wilson Gerwing T, Dmyterko M, Zochodne D, Johnston J, Verge V. Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. J Neurosci. 2005;25:758-67 pubmed
    ..In conclusion, although NGF drives inflammation-associated thermal hyperalgesia via its regulation of TRPV1 expression, NT-3 is now identified as a potent negative modulator of this state. ..
  2. Akhova O, Bainbridge M, Misra V. The neuronal host cell factor-binding protein Zhangfei inhibits herpes simplex virus replication. J Virol. 2005;79:14708-18 pubmed
  3. Kutz S, Hoberg E, Polley L, Jenkins E. Global warming is changing the dynamics of Arctic host-parasite systems. Proc Biol Sci. 2005;272:2571-6 pubmed
    ..This work establishes a foundation for understanding responses to climate change of other host-parasite systems, in the Arctic and globally. ..
  4. Shi M, Wei G, Pan W, Tabel H. Experimental African trypanosomiasis: a subset of pathogenic, IFN-gamma-producing, MHC class II-restricted CD4+ T cells mediates early mortality in highly susceptible mice. J Immunol. 2006;176:1724-32 pubmed
    ..We speculate that IL-10-producing CD4+ T cells might counteract this effect. ..
  5. Jenkins E, Kutz S, Hoberg E, Polley L. Bionomics of larvae of Parelaphostrongylus odocoilei (Nematoda: Protostrongylidae) in experimentally infected gastropod intermediate hosts. J Parasitol. 2006;92:298-305 pubmed
    ..Knowledge of the factors influencing larval bionomics provides the foundation for predicting temporal and spatial patterns of parasite distribution, abundance, and transmission. ..
  6. Grahn B, Sandmeyer L, Breaux C. Retinopathy of Coton de Tulear dogs: clinical manifestations, electroretinographic, ultrasonographic, fluorescein and indocyanine green angiographic, and optical coherence tomographic findings. Vet Ophthalmol. 2008;11:242-9 pubmed publisher
    ..To document the clinical manifestations, development, progression, and mode of inheritance of the retinopathy of Coton de Tulear dogs...
  7. Boison J, Lee S, Gedir R. A determinative and confirmatory method for residues of the metabolites of carbadox and olaquindox in porcine tissues. Anal Chim Acta. 2009;637:128-34 pubmed publisher
    ..050 ngkg(-1) and QCA and mQCA residues at concentrations >/=0.50 ngkg(-1)in bovine muscle, pork liver and muscle tissues...
  8. Shirazi A, Soleimani M, Karimi M, Nazari H, Ahmadi E, Heidari B. Vitrification of in vitro produced ovine embryos at various developmental stages using two methods. Cryobiology. 2010;60:204-10 pubmed publisher
    ..05). In conclusion, both the developmental stage of IVP ovine embryos and the method of vitrification have a significant effect on the viability and developmental competence of sheep embryos. ..
  9. Epp T, Waldner C, Berke O. Predicting geographical human risk of West Nile virus--Saskatchewan, 2003 and 2007. Can J Public Health. 2009;100:344-8 pubmed
    ..High-risk regions are characterized by less rainfall in June and July followed by higher temperatures in July and August with less vegetation and water coverage than low-risk regions. ..
  10. Chagpar R, Links P, Pastor M, Furber L, Hawrysh A, Chamberlain M, et al. Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A. 2010;107:5471-6 pubmed publisher
    ..This discovery will impact ongoing studies using therapeutics targeting the PI3K/PTEN/Akt pathway. ..
  11. Damiran D, Yu P. Chemical profile, rumen degradation kinetics, and energy value of four hull-less barley cultivars: comparison of the zero-amylose waxy, waxy, high-amylose, and normal starch cultivars. J Agric Food Chem. 2010;58:10553-9 pubmed publisher
    ..In summary, the HB cultivars with modified starch might be a better feed grain for ruminants than the normal starch HB. ..
  12. Ahmed K, Wang L, Munegowda M, Mulligan S, Mulligan S, Gordon J, et al. Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling. J Leukoc Biol. 2012;92:289-300 pubmed publisher
  13. Chen C, Epp T, Jenkins E, Waldner C, Curry P, Soos C. Modeling monthly variation of Culex tarsalis (Diptera: Culicidae) abundance and West Nile Virus infection rate in the Canadian Prairies. Int J Environ Res Public Health. 2013;10:3033-51 pubmed publisher
    ..tarsalis and the transmission intensity of WNV in the Canadian prairies. Furthermore, these models can also be used to examine the potential effects of climate change on the vector population abundance and the distribution of WNV. ..
  14. Naderi M, Jamwal A, Ferrari M, Niyogi S, Chivers D. Dopamine receptors participate in acquisition and consolidation of latent learning of spatial information in zebrafish (Danio rerio). Prog Neuropsychopharmacol Biol Psychiatry. 2016;67:21-30 pubmed publisher
    ..The current study opens the door to future studies to investigate the involvement of dopamine receptors in various aspects of cognitive processes. ..
  15. King T, Fang Y, Mahon E, Anderson D. Using a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3'-kinase. J Biol Chem. 2000;275:36450-6 pubmed
    ..This is the first description of a phosphotyrosine-independent SH2 domain interaction that requires basic residues on the SH2 ligand. ..
  16. Baxi M, Robertson J, Babiuk L, Tikoo S. Mutational analysis of early region 4 of bovine adenovirus type 3. Virology. 2001;290:153-63 pubmed
    ..0 kb. This is extremely useful for the construction of BAV3 vectors that express multiple genes and/or regulatory elements for gene therapy and vaccination...
  17. Ioannou X, Griebel P, Hecker R, Babiuk L, van Drunen Littel van den Hurk S. The immunogenicity and protective efficacy of bovine herpesvirus 1 glycoprotein D plus Emulsigen are increased by formulation with CpG oligodeoxynucleotides. J Virol. 2002;76:9002-10 pubmed
    ..Our results demonstrate the ability of CpG ODN to induce a strong and balanced immune response in a target species...
  18. Shi X, Karkut T, ALTING MEES M, Chamankhah M, Hemmingsen S, Hegedus D. Enhancing Escherichia coli electrotransformation competency by invoking physiological adaptations to stress and modifying membrane integrity. Anal Biochem. 2003;320:152-5 pubmed
  19. Pfeifer R. Cricopharyngeal achalasia in a dog. Can Vet J. 2003;44:993-5 pubmed
    ..A diagnosis of cricopharyngeal achalasia was made. After cricopharyngeal and thyropharyngeal myectomy, the dog was able to eat soft food without difficulty...
  20. He J, Xu H, Yang Y, Zhang X, Li X. Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats. Brain Res. 2004;1018:186-92 pubmed
    ..Our results suggest that OLA may be a neuroprotective agent and that its neuroprotective potential may contribute to its therapeutic effects in treatment of schizophrenia. ..
  21. Gentes M, Waldner C, Papp Z, Smits J. Effects of oil sands tailings compounds and harsh weather on mortality rates, growth and detoxification efforts in nestling tree swallows (Tachycineta bicolor). Environ Pollut. 2006;142:24-33 pubmed
    ..These results indicate that compared with reference birds, nestlings from OSPM-impacted wetlands may be less able to withstand additional stressors, which could decrease their chances of survival after fledging...
  22. Shirkey T, Siggers R, Goldade B, Marshall J, Drew M, Laarveld B, et al. Effects of commensal bacteria on intestinal morphology and expression of proinflammatory cytokines in the gnotobiotic pig. Exp Biol Med (Maywood). 2006;231:1333-45 pubmed
  23. van Drunen Littel van den Hurk S, Mapletoft J, Arsic N, Kovacs Nolan J. Immunopathology of RSV infection: prospects for developing vaccines without this complication. Rev Med Virol. 2007;17:5-34 pubmed
    ..Maternal vaccination may be the optimal strategy to protect the very young infants. ..
  24. Prasad K. A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complex. J Cardiovasc Pharmacol Ther. 2007;12:304-13 pubmed publisher
    ..These effects of FLC are not associated with reductions in serum lipids and oxidative stress. ..
  25. Brennan S, Ngeleka M, Philibert H, Forbes L, Allen A. Canine brucellosis in a Saskatchewan kennel. Can Vet J. 2008;49:703-8 pubmed
    ..Gender differences are described. The progestational, nongravid uterus, female spleen, and prostate gland are consistent sites of bacterial isolation. ..
  26. Zhao X, Town J, Li F, Zhang X, Cockcroft D, Gordon J. ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels. J Immunol. 2009;182:3213-22 pubmed publisher
    ..These data suggest that the beneficial effects of ELR-CXC chemokine antagonism arise through effects that occur at multiple levels, including epithelial cells, neutrophils, and alternate G protein-coupled receptors. ..
  27. Das U, Sharma R, Dimmock J. 1,5-diaryl-3-oxo-1,4-pentadienes: a case for antineoplastics with multiple targets. Curr Med Chem. 2009;16:2001-20 pubmed
    ..It is hoped that this eulogy of the importance of the dienone group will encourage researchers to consider incorporating this structural unit into candidate cytotoxins in the future. ..
  28. Zhao X, Town J, Yang A, Zhang X, Paur N, Sawicki G, et al. A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury. J Surg Res. 2010;162:264-73 pubmed publisher
    ..These results suggest that full-spectrum ELR-CXC chemokine antagonism has significant protective effects against I/R-induced local and remote organ injury. ..
  29. Mapletoft J, Latimer L, Babiuk L, van Drunen Littel van den Hurk S. Intranasal immunization of mice with a bovine respiratory syncytial virus vaccine induces superior immunity and protection compared to those by subcutaneous delivery or combinations of intranasal and subcutaneous prime-boost strategies. Clin Vaccine Immunol. 2010;17:23-35 pubmed publisher
  30. Booth J, Arsenault R, Napper S, Griebel P, Potter A, Babiuk L, et al. TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. J Innate Immun. 2010;2:483-94 pubmed publisher
    ..Our observations suggest a novel mechanism by which the host regulates TLR responses in TLR-expressing cells with regulatory functions. ..
  31. Mackenzie Dyck S, Attah Poku S, Juillard V, Babiuk L, van Drunen Littel van den Hurk S. The synthetic peptides bovine enteric ?-defensin (EBD), bovine neutrophil ?-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells. Vet Immunol Immunopathol. 2011;143:87-107 pubmed publisher
    ..These results are the first to describe chemotactic ability of synthetic bovine ?-defensins for immature bovine monocyte-derived DCs. ..
  32. Guigueno M, Elliott K, Levac J, Wayland M, Elliott J. Differential exposure of alpine ospreys to mercury: melting glaciers, hydrology or deposition patterns?. Environ Int. 2012;40:24-32 pubmed publisher
    ..Our study highlights the importance of physical patterns to the environmental chemistry of top predators. ..
  33. Woronuk G, Marquess F, James S, Palmer J, Berryere T, Deobald H, et al. Association of leptin genotypes with beef cattle characteristics. Anim Genet. 2012;43:608-10 pubmed publisher
    ..0001) with genotype, as animals of the TT, CT and CC genotypes weighed 484.2 ± 0.7, 488.0 ± 0.5 and 487.3 ± 0.6 kg, respectively, further underscoring the effects of this SNP on key market cattle characteristics. ..
  34. Salley T, Mishra M, Tiwari S, Jadhav A, Ndisang J. The heme oxygenase system rescues hepatic deterioration in the condition of obesity co-morbid with type-2 diabetes. PLoS ONE. 2013;8:e79270 pubmed publisher
  35. Tiong A, Richardson J. Characterization of rat cerebral cortical beta adrenoceptor subtypes using (-)-[125I]-iodocyanopindolol. J Recept Res. 1989;9:495-508 pubmed
    ..We have presented the first such characterization of rat cerebral cortical beta adrenoceptors with (-)ICYP in this study...
  36. Vandonselaar M, Hickie R, Quail J, Delbaere L. Trifluoperazine-induced conformational change in Ca(2+)-calmodulin. Nat Struct Biol. 1994;1:795-801 pubmed
    ..Two hydrophobic binding pockets, created by amino acid residues adjacent to Ca(2+)-coordinating residues, form the key recognition sites on Ca(2+)-CaM for both inhibitors and target enzymes. ..
  37. Kowalski J, Gilbert S, van Drunen Littel van den Hurk S, van den Hurk J, Babiuk L, Zamb T. Heat-shock promoter-driven synthesis of secreted bovine herpesvirus glycoproteins in transfected cells. Vaccine. 1993;11:1100-7 pubmed
    ..The continuous production demonstrated by this system is highly relevant to the efficient and economic manufacture of vaccines and other protein biopharmaceuticals. ..
  38. van Drunen Littel van den Hurk S, Braun R, Karvonen B, King T, Yoo D, Babiuk L. Immune responses and protection induced by DNA vaccines encoding bovine parainfluenza virus type 3 glycoproteins. Virology. 1999;260:35-46 pubmed
    ..A plasmid encoding a truncated, secreted form of HN induced a Th2-type immune response, regardless of the route of delivery. In cotton rats, HN- and F-encoding plasmids conferred protection from BPIV3 challenge. ..
  39. Nazarali A, Puthucode R, Leung V, Wolf L, Hao Z, Yeung J. Temporal and spatial expression of Hoxa-2 during murine palatogenesis. Cell Mol Neurobiol. 2000;20:269-90 pubmed
    ..This along with our new findings of the expression of the Hoxa-2 protein during palatogenesis has shed some light on the putative role of this gene in palate development. ..
  40. Davies G, McFie P, Khandelwal R, Roesler W. Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes. J Pharmacol Exp Ther. 2002;300:72-7 pubmed
    ..These data indicate that 1) up-regulation of the transactivation function of PPAR-gamma does not alone account for the induction of expression of PPAR-gamma by troglitazone, and 2) an antioxidant-related mechanism may be involved. ..
  41. De Rosemond S, Liber K. Wastewater treatment polymers identified as the toxic component of a diamond mine effluent. Environ Toxicol Chem. 2004;23:2234-42 pubmed
  42. Dickson L, MacNeil J, Lee S, Fesser A. Determination of beta-agonist residues in bovine urine using liquid chromatography-tandem mass spectrometry. J AOAC Int. 2005;88:46-56 pubmed
    ..Overall average recoveries ranged from 70-91%; recoveries were generally lower for salbutamol. The decision limits ranged from 0.4-1.0 microg/L, and detection capabilities from 0.6-1.7 microg/L...
  43. Vermette C, Russell A, Desai A, Hill J. Resolution of phenotypically distinct strains of Enterococcus spp. in a complex microbial community using cpn60 universal target sequencing. Microb Ecol. 2010;59:14-24 pubmed publisher
    ..Our results demonstrate that cpn60 sequences can be used to detect strain level changes in Enterococcus populations during succession in the fecal microbiota of growing pigs...
  44. Hobson K, Wunder M, Van Wilgenburg S, Clark R, Wassenaar L. A method for investigating population declines of migratory birds using stable isotopes: origins of harvested lesser scaup in North America. PLoS ONE. 2009;4:e7915 pubmed publisher
    ..Our approach for evaluating population declines of migratory birds (particularly game birds) synthesizes all available distributional data and exploits the advantages of intrinsic isotopic markers that link individuals to geography. ..
  45. Labiuk S, Lobanov V, Lawman Z, Snider M, Babiuk L, van Drunen Littel van den Hurk S. Bovine herpesvirus-1 US3 protein kinase: critical residues and involvement in the phosphorylation of VP22. J Gen Virol. 2010;91:1117-26 pubmed publisher
    ..These data demonstrate that BoHV-1 VP22 interacts with both CK2 and US3, and that CK2 is the major kinase phosphorylating VP22, with US3 playing a minor role...
  46. Polewicz D, Cadete V, Doroszko A, Hunter B, Sawicka J, Szczesna Cordary D, et al. Ischemia induced peroxynitrite dependent modifications of cardiomyocyte MLC1 increases its degradation by MMP-2 leading to contractile dysfunction. J Cell Mol Med. 2011;15:1136-47 pubmed publisher
  47. Toosi B, Seekallu S, Rawlings N. Effects of the rate and duration of physiological increases in serum FSH concentrations on emergence of follicular waves in cyclic ewes. Biol Reprod. 2010;83:648-55 pubmed publisher
  48. Gajadhar A, Lobanov V, Scandrett W, Campbell J, Al Adhami B. A novel Ehrlichia genotype detected in naturally infected cattle in North America. Vet Parasitol. 2010;173:324-9 pubmed publisher
    ..Although other Ehrlichia spp. are known to be pathogenic for animals and zoonotic, these features are presently unknown for this novel genotype. ..
  49. Sandmeyer L, Waldner C, Bauer B, Wen X, Bienzle D. Comparison of polymerase chain reaction tests for diagnosis of feline herpesvirus, Chlamydophila felis, and Mycoplasma spp. infection in cats with ocular disease in Canada. Can Vet J. 2010;51:629-33 pubmed
    ..76). There was slight agreement (kappa < 0.20) between the 3 laboratories for FHV-1 PCR and between the 2 commercial laboratories for both Chlamydophila felis (kappa = 0.2) and Mycoplasma spp. (kappa = 0.07) PCR...
  50. Abbasi S, Honaramooz A. Effects of recipient mouse strain, sex and gonadal status on the outcome of testis tissue xenografting. Reprod Fertil Dev. 2010;22:1279-86 pubmed publisher
    ..05). These results suggest that male SCID mice provide a suitable recipient model for testis tissue xenografting and that the mice do not need to be castrated for optimal results...
  51. McFie P, Banman S, Kary S, Stone S. Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum. J Biol Chem. 2011;286:28235-46 pubmed publisher
    ..Our findings demonstrate that DGAT2 is capable of catalyzing TG synthesis and promote its storage in cytosolic lipid droplets independent of its localization in the ER. ..
  52. Untereiner A, Dhar A, Liu J, Wu L. Increased renal methylglyoxal formation with down-regulation of PGC-1?-FBPase pathway in cystathionine ?-lyase knockout mice. PLoS ONE. 2011;6:e29592 pubmed publisher
    ..In conclusion, overproduction of MG in CSE(-/-) mice is due to a H(2)S-mediated down-regulation of the PGC-1?-FBPase pathway, further suggesting the important role of H(2)S in the regulation of glucose metabolism and MG generation. ..
  53. Wobeser B, Hill J, Jackson M, Kidney B, Mayer M, Townsend H, et al. Localization of Bovine papillomavirus in equine sarcoids and inflammatory skin conditions of horses using laser microdissection and two forms of DNA amplification. J Vet Diagn Invest. 2012;24:32-41 pubmed publisher
    ..03 and P = 0.01, respectively). Results suggest that BPV is commonly found in normal and inflamed equine skin, and it is likely an important predisposing factor in the development of sarcoids. ..
  54. Scandrett W, Gajadhar A. Assessment of domestic goats as a patent host of Elaphostrongylus cervi. J Parasitol. 2002;88:93-6 pubmed
    ..The 2 positive control red deer became patent with dorsal-spined larvae consistent with E. cervi at 131 DPI. These findings suggest that goats, at least those breeds utilized in this study, are not suitable patent hosts for E. cervi...
  55. Zhang L, Gomis S, Tikoo S. Evaluation of promoters for foreign gene expression in the E3 region of bovine adenovirus type-3. Virus Res. 2005;110:169-76 pubmed
    ..These results suggest that BAdV vectors with the MCMV IE promoter may be useful for transgene expression and the development of vaccines...
  56. Shi M, Ye Z, Umeshappa K, Moyana T, Xiang J. Alpha tumor necrosis factor contributes to CD8(+) T cell survival in the transition phase. Biochem Biophys Res Commun. 2007;360:702-7 pubmed
  57. Kiros T, Power C, Wei G, Bretscher P. Immunization of newborn and adult mice with low numbers of BCG leads to Th1 responses, Th1 imprints and enhanced protection upon BCG challenge. Immunotherapy. 2010;2:25-35 pubmed publisher
    ..In this trial, the highest dose of BCG, which had insignificant side effects, was administered to over 250,000 human subjects. This high-dose vaccination resulted in insignificant protection against tuberculosis. ..
  58. Epp T, Waldner C, Argue C. Case-control study investigating an anthrax outbreak in Saskatchewan, Canada--Summer 2006. Can Vet J. 2010;51:973-8 pubmed
    ..3; 95% CI: 2.6 to 15.3). Timing of vaccination in case herds was also significantly associated with the occurrence of subsequent deaths on these farms (P = 0.001). ..
  59. Mankidy R, Wiseman S, Ma H, Giesy J. Biological impact of phthalates. Toxicol Lett. 2013;217:50-8 pubmed publisher
    ..Such cumulative assessment of multiple biological parameters is more realistic, and offers the possibility of more accurately identifying the CMTA. ..
  60. Desin T, Koster W, Potter A. Salmonella vaccines in poultry: past, present and future. Expert Rev Vaccines. 2013;12:87-96 pubmed publisher
  61. Aduma P, Gupta S, Stuart A, Tourigny G. Deoxyribonucleoside triphosphate pools of herpes simplex virus infected cells: the influence of selective antiherpes agents and the role of the deaminase pathway. Biochem Cell Biol. 1991;69:409-14 pubmed
    ..These results indicate that during viral replication the bulk of the thymidine nucleotides are derived from the dCyd/dCMP deaminase de novo pathway. ..
  62. Liang X, Tang M, Manns B, Babiuk L, Zamb T. Identification and deletion mutagenesis of the bovine herpesvirus 1 dUTPase gene and a gene homologous to herpes simplex virus UL49.5. Virology. 1993;195:42-50 pubmed
    ..5 gene. Since our dUTPase negative mutant was fully viable and since the mutant was constructed such that the UL49.5 gene was also deleted, both the dUTPase and the UL49.5 gene homolog are not required for virus growth in cell culture. ..
  63. Delbaere L, Sudom A, Prasad L, Leduc Y, Goldie H. Structure/function studies of phosphoryl transfer by phosphoenolpyruvate carboxykinase. Biochim Biophys Acta. 2004;1697:271-8 pubmed
    ..There are three positively charged groups that interact with the fluorine atoms, which are complementary to the three negative charges that would occur for an associative transition state. ..
  64. Joly D, Messier F. The distribution of Echinococcus granulosus in moose: evidence for parasite-induced vulnerability to predation by wolves?. Oecologia. 2004;140:586-90 pubmed
    ..This increase in predation rate due to parasite infection may influence the role of wolves in regulating moose populations. We discuss alternative explanations for the negative correlation between predation rate and parasite aggregation...
  65. Oumouna M, Mapletoft J, Karvonen B, Babiuk L, van Drunen Littel van den Hurk S. Formulation with CpG oligodeoxynucleotides prevents induction of pulmonary immunopathology following priming with formalin-inactivated or commercial killed bovine respiratory syncytial virus vaccine. J Virol. 2005;79:2024-32 pubmed
    ..Finally, when formulated with CpG ODN, both FI-BRSV and K-BRSV significantly reduced virus production after challenge with BRSV. ..
  66. Patel A, Tikoo S. 293T cells expressing simian virus 40 T antigen are semi-permissive to bovine adenovirus type 3 infection. J Gen Virol. 2006;87:817-21 pubmed
    ..Electron microscopy and virus growth kinetics demonstrated the formation of progeny virus in 293T cells. The SV-40 T antigens act to overcome a barrier in BAdV-3 DNA replication in 293 cells...
  67. Hwang Y, Larivière S, Messier F. Energetic consequences and ecological significance of heterothermy and social thermoregulation in striped skunks (Mephitis mephitis). Physiol Biochem Zool. 2007;80:138-45 pubmed
  68. Waldner C, Clark E. Association between exposure to emissions from the oil and gas industry and pathology of the immune, nervous, and respiratory systems, and skeletal and cardiac muscle in beef calves. Arch Environ Occup Health. 2009;64:6-27 pubmed publisher
    ..During gestation, increasing exposure to sulfur dioxide was associated with increased odds of lesions in either the skeletal muscle or myocardium...
  69. Schultke E, Fiedler S, Nemoz C, Ogieglo L, Kelly M, Crawford P, et al. Synchrotron-based intra-venous K-edge digital subtraction angiography in a pig model: a feasibility study. Eur J Radiol. 2010;73:677-81 pubmed publisher
    ..KEDSA images in radiography mode allowed the visualization of intracranial arteries of less than 1.5mm diameter. ..
  70. Zhang B, Wang X, Nazarali A. Ascorbic acid reverses valproic acid-induced inhibition of hoxa2 and maintains glutathione homeostasis in mouse embryos in culture. Cell Mol Neurobiol. 2010;30:137-48 pubmed publisher
  71. Galezowski A, Snead E, Kidney B, Jackson M. C-reactive protein as a prognostic indicator in dogs with acute abdomen syndrome. J Vet Diagn Invest. 2010;22:395-401 pubmed
    ..Also, serum CRP may be better in detecting tissue injury and/or inflammation at presentation than WBC counts in select cases. ..
  72. van Beest F, Vander Wal E, Stronen A, Paquet P, Brook R. Temporal variation in site fidelity: scale-dependent effects of forage abundance and predation risk in a non-migratory large herbivore. Oecologia. 2013;173:409-20 pubmed publisher
    ..Insight into the scale-dependent behavioural responses of ungulate populations to limiting factors such as predation risk and forage variability is essential to infer the fitness costs incurred. ..
  73. Lussier A, Lebedeva K, Fenton E, Guskjolen A, Caruncho H, Kalynchuk L. The progressive development of depression-like behavior in corticosterone-treated rats is paralleled by slowed granule cell maturation and decreased reelin expression in the adult dentate gyrus. Neuropharmacology. 2013;71:174-83 pubmed publisher
    ..These results support our hypothesis that reelin plays a role in the pathogenesis of depression and suggest that reelin could be an important target for the development of novel therapeutics for the treatment of depression. ..
  74. Vidovic S, Tsoi S, Medihala P, Liu J, Wylie J, Levett P, et al. Molecular and antimicrobial susceptibility analyses distinguish clinical from bovine Escherichia coli O157 strains. J Clin Microbiol. 2013;51:2082-8 pubmed publisher
    ..These findings imply that antimicrobial resistance generated among bovine strains of E. coli O157 has a large impact on the population of this human pathogen...
  75. Albornoz R, Aschenbach J, Barreda D, Penner G. Feed restriction reduces short-chain fatty acid absorption across the reticulorumen of beef cattle independent of diet. J Anim Sci. 2013;91:4730-8 pubmed publisher
    ..It can be concluded that severe short-term FR had a negative impact on ruminal SCFA absorption and energy balance and that altering the F:C of the diet does not mitigate these effects. ..
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