Experts and Doctors on pyruvic acid in Guelph, Ontario, Canada

Summary

Locale: Guelph, Ontario, Canada
Topic: pyruvic acid

Top Publications

  1. Smith A, Bruce C, Dyck D. AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscle. J Physiol. 2005;565:537-46 pubmed
    ..In conclusion, AMPK appears to be an important regulator of both FA metabolism and glucose oxidation in resting skeletal muscle. ..
  2. Stellingwerff T, Leblanc P, Hollidge M, Heigenhauser G, Spriet L. Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise. Am J Physiol Endocrinol Metab. 2006;290:E1180-90 pubmed
    ..The tighter metabolic match between pyruvate production and oxidation resulted in a decrease in total lactate production and efflux over 40 min of exercise during hyperoxia. ..
  3. Clark S, Di Leo R, Dhanoa P, Van Cauwenberghe O, Mullen R, Shelp B. Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate. J Exp Bot. 2009;60:1743-57 pubmed publisher
    ..A GABA-T with dual functions suggests the potential for interaction between GABA metabolism and photorespiratory glyoxylate production. ..
  4. Clark S, Di Leo R, Van Cauwenberghe O, Mullen R, Shelp B. Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate. J Exp Bot. 2009;60:3255-67 pubmed publisher
    ..Overall, these findings, together with recent information about rice and pepper GABA-Ts, indicate that the subcellular distribution of GABA-T in the plant kingdom is highly variable...
  5. Baker P, Carere J, Seah S. Substrate specificity, substrate channeling, and allostery in BphJ: an acylating aldehyde dehydrogenase associated with the pyruvate aldolase BphI. Biochemistry. 2012;51:4558-67 pubmed
    ..The results demonstrate that the dehydrogenase coordinates the catalytic activity of BphI through allostery rather than through aldehyde channeling. ..

Detail Information

Publications5

  1. Smith A, Bruce C, Dyck D. AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscle. J Physiol. 2005;565:537-46 pubmed
    ..In conclusion, AMPK appears to be an important regulator of both FA metabolism and glucose oxidation in resting skeletal muscle. ..
  2. Stellingwerff T, Leblanc P, Hollidge M, Heigenhauser G, Spriet L. Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise. Am J Physiol Endocrinol Metab. 2006;290:E1180-90 pubmed
    ..The tighter metabolic match between pyruvate production and oxidation resulted in a decrease in total lactate production and efflux over 40 min of exercise during hyperoxia. ..
  3. Clark S, Di Leo R, Dhanoa P, Van Cauwenberghe O, Mullen R, Shelp B. Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate. J Exp Bot. 2009;60:1743-57 pubmed publisher
    ..A GABA-T with dual functions suggests the potential for interaction between GABA metabolism and photorespiratory glyoxylate production. ..
  4. Clark S, Di Leo R, Van Cauwenberghe O, Mullen R, Shelp B. Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate. J Exp Bot. 2009;60:3255-67 pubmed publisher
    ..Overall, these findings, together with recent information about rice and pepper GABA-Ts, indicate that the subcellular distribution of GABA-T in the plant kingdom is highly variable...
  5. Baker P, Carere J, Seah S. Substrate specificity, substrate channeling, and allostery in BphJ: an acylating aldehyde dehydrogenase associated with the pyruvate aldolase BphI. Biochemistry. 2012;51:4558-67 pubmed
    ..The results demonstrate that the dehydrogenase coordinates the catalytic activity of BphI through allostery rather than through aldehyde channeling. ..