Experts and Doctors on deoxyribonucleases in Toronto, Ontario, Canada

Summary

Locale: Toronto, Ontario, Canada
Topic: deoxyribonucleases

Top Publications

  1. Lechardeur D, Dougaparsad S, Nemes C, Lukacs G. Oligomerization state of the DNA fragmentation factor in normal and apoptotic cells. J Biol Chem. 2005;280:40216-25 pubmed
    ..In apoptotic cells, endogenous and exogenous CAD forms limited oligomers, representing the active nuclease. A model is proposed for the rearrangement of the DFF subunit stoichiometry in cells undergoing programmed cell death. ..
  2. Babu M, Beloglazova N, Flick R, Graham C, Skarina T, Nocek B, et al. A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol Microbiol. 2011;79:484-502 pubmed publisher
  3. Kumar A, Beloglazova N, Bundalovic Torma C, Phanse S, Deineko V, Gagarinova A, et al. Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli. Cell Rep. 2016;14:648-661 pubmed publisher
    ..Analyses of pan-bacterial conservation patterns suggest that DDR mechanisms and functional relationships are near universal, highlighting a modular and highly adaptive genomic stress response. ..

Detail Information

Publications3

  1. Lechardeur D, Dougaparsad S, Nemes C, Lukacs G. Oligomerization state of the DNA fragmentation factor in normal and apoptotic cells. J Biol Chem. 2005;280:40216-25 pubmed
    ..In apoptotic cells, endogenous and exogenous CAD forms limited oligomers, representing the active nuclease. A model is proposed for the rearrangement of the DFF subunit stoichiometry in cells undergoing programmed cell death. ..
  2. Babu M, Beloglazova N, Flick R, Graham C, Skarina T, Nocek B, et al. A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol Microbiol. 2011;79:484-502 pubmed publisher
  3. Kumar A, Beloglazova N, Bundalovic Torma C, Phanse S, Deineko V, Gagarinova A, et al. Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli. Cell Rep. 2016;14:648-661 pubmed publisher
    ..Analyses of pan-bacterial conservation patterns suggest that DDR mechanisms and functional relationships are near universal, highlighting a modular and highly adaptive genomic stress response. ..