Experts and Doctors on amino acids in Ottawa, Ontario, Canada

Summary

Locale: Ottawa, Ontario, Canada
Topic: amino acids

Top Publications

  1. Head J, Hahn M, Kennedy S. Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species. Environ Sci Technol. 2008;42:7535-41 pubmed
    ..Given the large degree of variation in species sensitivity and the paucity of species-specific toxicity data, a genetic screen based on these findings could substantially improve risk assessment for dioxin-like compounds in wild birds...
  2. Schenk M, Koppisetty C, Santos D, Carmona E, Bhatia S, Nyholm P, et al. Interaction of arylsulfatase-A (ASA) with its natural sulfoglycolipid substrates: a computational and site-directed mutagenesis study. Glycoconj J. 2009;26:1029-45 pubmed publisher
    ..However, our dockings suggested additional intermolecular hydrogen bonding and hydrophobic interactions between ASA and SGC/SGG, thus contributing to the specificity of SGC/SGG as natural substrates. ..
  3. Pelland A, Corbett H, Baltz J. Amino Acid transport mechanisms in mouse oocytes during growth and meiotic maturation. Biol Reprod. 2009;81:1041-54 pubmed publisher
    ..In some cases, however, follicular cells coupled to the oocyte enhanced uptake of amino acids by the same systems present in the oocyte. ..
  4. Richards T, Wang F, Liu L, Baltz J. Rescue of postcompaction-stage mouse embryo development from hypertonicity by amino acid transporter substrates that may function as organic osmolytes. Biol Reprod. 2010;82:769-77 pubmed publisher
  5. Rodrigue N, Philippe H, Lartillot N. Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles. Proc Natl Acad Sci U S A. 2010;107:4629-34 pubmed publisher

Detail Information

Publications5

  1. Head J, Hahn M, Kennedy S. Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species. Environ Sci Technol. 2008;42:7535-41 pubmed
    ..Given the large degree of variation in species sensitivity and the paucity of species-specific toxicity data, a genetic screen based on these findings could substantially improve risk assessment for dioxin-like compounds in wild birds...
  2. Schenk M, Koppisetty C, Santos D, Carmona E, Bhatia S, Nyholm P, et al. Interaction of arylsulfatase-A (ASA) with its natural sulfoglycolipid substrates: a computational and site-directed mutagenesis study. Glycoconj J. 2009;26:1029-45 pubmed publisher
    ..However, our dockings suggested additional intermolecular hydrogen bonding and hydrophobic interactions between ASA and SGC/SGG, thus contributing to the specificity of SGC/SGG as natural substrates. ..
  3. Pelland A, Corbett H, Baltz J. Amino Acid transport mechanisms in mouse oocytes during growth and meiotic maturation. Biol Reprod. 2009;81:1041-54 pubmed publisher
    ..In some cases, however, follicular cells coupled to the oocyte enhanced uptake of amino acids by the same systems present in the oocyte. ..
  4. Richards T, Wang F, Liu L, Baltz J. Rescue of postcompaction-stage mouse embryo development from hypertonicity by amino acid transporter substrates that may function as organic osmolytes. Biol Reprod. 2010;82:769-77 pubmed publisher
  5. Rodrigue N, Philippe H, Lartillot N. Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles. Proc Natl Acad Sci U S A. 2010;107:4629-34 pubmed publisher