Experts and Doctors on in Ontario, Canada
Locale: Ontario, Canada
Nicol C, Harrison M, Laposa R, Gimelshtein I, Wells P. A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. Nat Genet. 1995;10:181-7 pubmed
..These results provide the first direct evidence that p53 may be an important teratological suppressor gene which protects the embryo from DNA-damaging chemicals and developmental oxidative stress. ..
Hervé J, Crump D, Jones S, Mundy L, Giesy J, Zwiernik M, et al
. Cytochrome P4501A induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and two chlorinated dibenzofurans in primary hepatocyte cultures of three avian species. Toxicol Sci. 2010;113:380-91 pubmed publisher
..This study indicates that PeCDF is more potent than TCDD in ring-necked pheasant and Japanese quail hepatocytes and that ring-necked pheasant, Japanese quail, and chicken hepatocytes are equally sensitive to CYP1A induction by PeCDF. ..