Experts and Doctors on fundulidae in Nova Scotia, Canada
Locale: Nova Scotia, Canada
Marshall W, Katoh F, Main H, Sers N, Cozzi R. Focal adhesion kinase and beta1 integrin regulation of Na+, K+, 2Cl- cotransporter in osmosensing ion transporting cells of killifish, Fundulus heteroclitus. Comp Biochem Physiol A Mol Integr Physiol. 2008;150:288-300 pubmed publisher
Marshall W, Howard J, Cozzi R, Lynch E. NaCl and fluid secretion by the intestine of the teleost Fundulus heteroclitus: involvement of CFTR. J Exp Biol. 2002;205:745-58 pubmed
Marshall W, Singer T. Cystic fibrosis transmembrane conductance regulator in teleost fish. Biochim Biophys Acta. 2002;1566:16-27 pubmed
..The facility with which teleosts regulate CFTR expression and activation during salinity adaptation make this system an appealing model for the expression and trafficking operation of this labile gene product...
Marshall W, Ossum C, Hoffmann E. Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium. J Exp Biol. 2005;208:1063-77 pubmed
Wilson B, Burnett D, Rappaport R, Parry L, Fletcher E. Relaxin-3 and RXFP3 expression, and steroidogenic actions in the ovary of teleost fish. Comp Biochem Physiol A Mol Integr Physiol. 2009;153:69-74 pubmed publisher
..Relaxin-3 appeared to suppress the release of MIS production. This suggests that relaxin peptides may be involved with estradiol-dependant events in follicular development. ..
Marshall W, Watters K, Hovdestad L, Cozzi R, Katoh F. CFTR Cl- channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish. J Exp Biol. 2009;212:2365-77 pubmed publisher
..We conclude that hormone mediated, cAMP dependent and osmotically mediated, cAMP independent pathways converge on a mechanism to activate CFTR and Cl(-) secretion, possibly through tyrosine phosphorylation of CFTR by FAK. ..