Experts and Doctors on middle aged in Edmonton, Alberta, Canada


Locale: Edmonton, Alberta, Canada
Topic: middle aged

Top Publications

  1. Webster L, Michelakis E, Davis T, Archer S. Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial. Arch Intern Med. 2004;164:514-20 pubmed
  2. Devani A, Barankin B. Dermacase. Chondrodermatitis nodularis chronica helicis. Can Fam Physician. 2007;53:821, 837 pubmed
  3. Yuksel N, Majumdar S, Biggs C, Tsuyuki R. Community pharmacist-initiated screening program for osteoporosis: randomized controlled trial. Osteoporos Int. 2010;21:391-8 pubmed publisher
    ..A pharmacist screening program doubled the number of patients tested for osteoporosis. Nevertheless, many patients eligible for BMD did not receive appropriate care suggesting more intensive interventions are needed. ..
  4. Johnson J, Vermeulen S, Toth E, Hemmelgarn B, Ralph Campbell K, Hugel G, et al. Increasing incidence and prevalence of diabetes among the Status Aboriginal population in urban and rural Alberta, 1995-2006. Can J Public Health. 2009;100:231-6 pubmed
    ..109). Prevalence and incidence of diagnosed diabetes were highest in Status Aboriginal women, but these rates have increased faster in men over the past decade, regardless of their location of residence. ..
  5. Yeung J, Goodman K, Fedorak R. Inadequate knowledge of immunization guidelines: a missed opportunity for preventing infection in immunocompromised IBD patients. Inflamm Bowel Dis. 2012;18:34-40 pubmed publisher
    ..Substantial proportions of IBD patients and gastroenterologists lack adequate knowledge of established immunization guidelines prior to initiation of immunosuppressive therapy. ..
  6. Biron V, Mohamed A, Hendzel M, Alan Underhill D, Seikaly H. Epigenetic differences between human papillomavirus-positive and -negative oropharyngeal squamous cell carcinomas. J Otolaryngol Head Neck Surg. 2012;41 Suppl 1:S65-70 pubmed
    ..HPV-positive and -negative OPSCCs have distinct epigenetic profiles representing broad gene expression differences between these tumours. ..
  7. Wu M, Assassi S, Salazar G, Pedroza C, Gorlova O, Chen W, et al. Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients. Arthritis Res Ther. 2016;18:20 pubmed publisher
    ..However, these associations also did not replicate in the validation cohort. Our results add new evidence that SSc and SSc-related ILD are genetically distinct from IIP, although they share phenotypic similarities. ..
  8. Stanton T, Kawchuk G. The effect of abdominal stabilization contractions on posteroanterior spinal stiffness. Spine (Phila Pa 1976). 2008;33:694-701 pubmed publisher
    ..Future work is required to assess the long-term effect of repeated abdominal brace and hollow contractions on PA spinal stiffness and low back pain. ..
  9. Wilke M, French M, Goh Y, Ryan E, Jones P, Clandinin M. Synthesis of specific fatty acids contributes to VLDL-triacylglycerol composition in humans with and without type 2 diabetes. Diabetologia. 2009;52:1628-37 pubmed publisher
    ..The implications of this finding for our understanding of lipid metabolism in diabetes require further investigation. ..

More Information

Publications380 found, 100 shown here

  1. Rudnisky C, Belin M, Todani A, Al Arfaj K, Ament J, Zerbe B, et al. Risk factors for the development of retroprosthetic membranes with Boston keratoprosthesis type 1: multicenter study results. Ophthalmology. 2012;119:951-5 pubmed publisher
    ..Eyes at the highest risk of RPM development are those receiving corneal replacement for infectious keratitis and aniridia. ..
  2. Soo I, Siffledeen J, Siminoski K, McQueen B, Fedorak R. Risedronate improves bone mineral density in Crohn's disease: a two year randomized controlled clinical trial. J Crohns Colitis. 2012;6:777-86 pubmed publisher
    ..04). Risedronate, in addition to daily calcium and vitamin D supplementation, is superior to calcium and vitamin D alone in improving femoral trochanter and total hip BMD in patients with Crohn's disease. ..
  3. Eurich D, Simpson S, Senthilselvan A, Asche C, Sandhu Minhas J, McAlister F. Comparative safety and effectiveness of sitagliptin in patients with type 2 diabetes: retrospective population based cohort study. BMJ. 2013;346:f2267 pubmed publisher
    ..Most patients prescribed sitagliptin in this cohort were concordant with clinical practice guidelines, in that it was used as add-on treatment. ..
  4. Kovacs Burns K, Nicolucci A, Holt R, Willaing I, Hermanns N, Kalra S, et al. Diabetes Attitudes, Wishes and Needs second study (DAWN2™): cross-national benchmarking indicators for family members living with people with diabetes. Diabet Med. 2013;30:778-88 pubmed publisher
    ..DAWN2 provides benchmarking indicators of family members' psychosocial needs that will help identify the support required for, and from, them to improve the lives of people with diabetes and their families. ..
  5. Juby A, Hanly M, Lukaczer D. Clinical challenges in thyroid disease: Time for a new approach?. Maturitas. 2016;87:72-8 pubmed publisher
    ..This article discusses these important clinical issues in more detail, with some practical tips especially for an approach to the "non-responders" to the current traditional therapeutic approach. ..
  6. Majumdar S, McAlister F, Cree M, Chang W, Packer M, Armstrong P. Do evidence-based treatments provide incremental benefits to patients with congestive heart failure already receiving angiotensin-converting enzyme inhibitors? A secondary analysis of one-year outcomes from the Assessment of Treatment with Lisinopril. Clin Ther. 2004;26:694-703 pubmed
    ..These findings support treatment guidelines that recommend the concurrent use of all available proven efficacious treatment in patients with advanced CHF. ..
  7. Dick B, Verrier M, Harker K, Rashiq S. Disruption of cognitive function in fibromyalgia syndrome. Pain. 2008;139:610-6 pubmed publisher
    ..It is likely that many factors, including disrupted cognition, play a role in the reduced quality of life reported by individuals with FMS. ..
  8. Kumar D, Husain S, Chen M, Moussa G, Himsworth D, Manuel O, et al. A prospective molecular surveillance study evaluating the clinical impact of community-acquired respiratory viruses in lung transplant recipients. Transplantation. 2010;89:1028-33 pubmed publisher
    ..In a significant percentage of patients, symptomatic or asymptomatic viral infection is a trigger for acute rejection and obliterative bronchiolitis/BOS. ..
  9. Zayas G, Chiang M, Wong E, Macdonald F, Lange C, Senthilselvan A, et al. Cough aerosol in healthy participants: fundamental knowledge to optimize droplet-spread infectious respiratory disease management. BMC Pulm Med. 2012;12:11 pubmed publisher
    ..The objective of the current study was to characterize the human cough aerosol pattern with the aim of developing a standard human cough bioaerosol model for Influenza Pandemic control...
  10. Tran B. Quality of life outcomes of antiretroviral treatment for HIV/AIDS patients in Vietnam. PLoS ONE. 2012;7:e41062 pubmed publisher
    ..This study assessed health-related quality of life (HRQOL) and its related factors in HIV/AIDS patients taking antiretroviral treatment (ART) in Vietnam...
  11. Sellares J, Reeve J, Loupy A, Mengel M, Sis B, Skene A, et al. Molecular diagnosis of antibody-mediated rejection in human kidney transplants. Am J Transplant. 2013;13:971-983 pubmed publisher
    ..We conclude that microarray assessment of gene expression can assign a probability of ABMR to transplant biopsies without knowledge of HLA antibody status, histology, or C4d staining, and predicts future failure. ..
  12. Brummell S, Seymour J, Higginbottom G. Cardiopulmonary resuscitation decisions in the emergency department: An ethnography of tacit knowledge in practice. Soc Sci Med. 2016;156:47-54 pubmed publisher
    ..This enables them to construct an acceptable death in highly challenging circumstances. ..
  13. Kalra S, Tai P, Genge A, Arnold D. Rapid improvement in cortical neuronal integrity in amyotrophic lateral sclerosis detected by proton magnetic resonance spectroscopic imaging. J Neurol. 2006;253:1060-3 pubmed
    ..Improvement in cortical neuronal metabolic function in the motor cortex occurs early with riluzole treatment. ..
  14. Noor R, Shuaib U, Wang C, Todd K, Ghani U, Schwindt B, et al. High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis. Atherosclerosis. 2007;192:92-9 pubmed
    ..HDL also prevents EPC apoptosis through inhibition of caspase-3 activity suggesting a possible mechanism for its positive effects on circulating EPC numbers. ..
  15. Karvellas C, Pink F, McPhail M, Cross T, Auzinger G, Bernal W, et al. Predictors of bacteraemia and mortality in patients with acute liver failure. Intensive Care Med. 2009;35:1390-6 pubmed publisher
    ..Transplantation was protective (OR 0.20). In this study, severity of hepatic encephalopathy and SIRS score >1 were predictive of bacteraemia. APACHEII was independently predictive of mortality in all ALF patients but not bacteraemia. ..
  16. Kowalczewski J, Chong S, Galea M, Prochazka A. In-home tele-rehabilitation improves tetraplegic hand function. Neurorehabil Neural Repair. 2011;25:412-22 pubmed publisher
    ..Functional electrical stimulation (FES) combined with exercise therapy (ET) can improve hand function, but delivering the treatment is problematic...
  17. Honardoust D, Varkey M, Hori K, Ding J, Shankowsky H, Tredget E. Small leucine-rich proteoglycans, decorin and fibromodulin, are reduced in postburn hypertrophic scar. Wound Repair Regen. 2011;19:368-78 pubmed publisher
    ..In contrast, these proteoglycans were absent or weakly expressed in HTS. The findings suggest that down-regulation of SLRPs after wound healing in deep injuries to the skin plays an important role in the development of fibrosis and HTS. ..
  18. Majumdar S, Lix L, Yogendran M, Morin S, Metge C, Leslie W. Population-based trends in osteoporosis management after new initiations of long-term systemic glucocorticoids (1998-2008). J Clin Endocrinol Metab. 2012;97:1236-42 pubmed publisher
    ..Interventions to improve GIOP prevention, especially targeting younger patients, men, and nonspecialists, are needed. ..
  19. Parliament M, Jha N, Rapp E, Smith C, MacKinnon J, Nabholtz J, et al. Concurrent weekly carboplatin and radiotherapy for nasopharyngeal carcinoma: report of a joint phase II study. Radiother Oncol. 2001;58:131-6 pubmed
    ..At present, there is no data to suggest that carboplatin can replace cisplatin for concurrent chemoradiation for NPC. ..
  20. Lalu M, Pasini E, Schulze C, Ferrari Vivaldi M, Ferrari Vivaldi G, Bachetti T, et al. Ischaemia-reperfusion injury activates matrix metalloproteinases in the human heart. Eur Heart J. 2005;26:27-35 pubmed
    ..This is the first correlation of MMP myocardial activity with cardiac function in humans. The early increase in MMP activity produces a proteolytic environment that may contribute to myocardial stunning injury in humans. ..
  21. Ashworth N, Peloso P, Muhajarine N, Stang M. Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study. J Rheumatol. 2005;32:2212-7 pubmed
    ..It appears that inherent gastroprotective strategies with Arthrotec and to a lesser extent with nabumetone do translate into decreased serious GI side effects at the population level in the short term. ..
  22. Toso C, Asthana S, Bigam D, Shapiro A, Kneteman N. Reassessing selection criteria prior to liver transplantation for hepatocellular carcinoma utilizing the Scientific Registry of Transplant Recipients database. Hepatology. 2009;49:832-8 pubmed publisher
    ..A composite patient selection score combining TTV and AFP was the most effective of all tested staging criteria for the prediction of posttransplant patient survival for candidates with HCC. ..
  23. Olsen S, Bhutani M. Multiple cavitating nodules in a renal transplant recipient. Can Respir J. 2009;16:195-7 pubmed
    ..The present case represents a unique radiographic presentation of post-transplant lymphoproliferative disorder not previously reported in the literature. ..
  24. Sadowski D, Ackah F, Jiang B, Svenson L. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22:e256-61 pubmed publisher
    ..63/100,000 and 10.82/100,000, respectively. The disease appears to have a stable incidence but a rising prevalence. Survival of achalasia cases is significantly less than age-matched healthy controls. ..
  25. Freund P, Watson J, Gilmour G, Gaillard F, Sauve Y. Differential changes in retina function with normal aging in humans. Doc Ophthalmol. 2011;122:177-90 pubmed publisher
    ..9 and 2 s. These results denote that aging of the healthy retina is accompanied by specific functional changes, which must be taken into account to optimally diagnose potential pathologies. ..
  26. Roa W, Kim J, Razzak R, DU H, Guo L, Singh R, et al. Sputum microRNA profiling: a novel approach for the early detection of non-small cell lung cancer. Clin Invest Med. 2012;35:E271 pubmed
  27. Marrie T, Raoult D, La Scola B, Birtles R, De Carolis E. Legionella-like and other amoebal pathogens as agents of community-acquired pneumonia. Emerg Infect Dis. 2001;7:1026-9 pubmed
    ..We found that LLAPs play a role (albeit an infrequent one) in community-acquired pneumonia, usually as a co-pathogen but sometimes as the sole identified pathogen. ..
  28. Shariatzadeh M, Huang J, Tyrrell G, Johnson M, Marrie T. Bacteremic pneumococcal pneumonia: a prospective study in Edmonton and neighboring municipalities. Medicine (Baltimore). 2005;84:147-61 pubmed
    ..We identified 3 subsets of patients with BPP according to the site of care (ambulatory, ward, and ICU), with different outcomes. ..
  29. Damaraju S, Murray D, Dufour J, Carandang D, Myrehaug S, Fallone G, et al. Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer. Clin Cancer Res. 2006;12:2545-54 pubmed
    ..In this study, we identified SNPs in LIG4, ERCC2, and CYP2D6 genes as putative markers to predict individuals at risk for complications arising from radiation therapy in prostate cancer. ..
  30. Luyckx V, Yip A, Sofianou L, Jhangri G, Mueller T, Naicker S. Cardiac function in an African dialysis population with a low prevalence of pre-existing cardiovascular disease. Ren Fail. 2009;31:211-20 pubmed publisher
    ..This finding suggests that dialysis and uremia per se, in the absence of pre-existing cardiac disease, may not be major contributors to cardiovascular morbidity. ..
  31. Oh D, Chua N, Street L, Stewart D. Treatment of patients with secondary central nervous system lymphoma with high-dose busulfan/thiotepa-based conditioning and autologous stem cell transplant. Leuk Lymphoma. 2016;57:28-33 pubmed publisher
    ..8 months (4.2-113.6), the 2-year actuarial rate of progression-free survival was 76.1%. In conclusion, our results demonstrate encouraging survival outcomes for patients with SCNSL treated with R-BuMelTt and ASCT. ..
  32. Schadendorf D, Larkin J, Wolchok J, Hodi F, Chiarion Sileni V, Gonzalez R, et al. Health-related quality of life results from the phase III CheckMate 067 study. Eur J Cancer. 2017;82:80-91 pubmed publisher
    ..The finding that the difference in grade 3/4 AEs between the arms did not translate into clinically meaningful differences in the reported HRQoL may be relevant in the clinical setting. NCT01844505. ..
  33. Froese K, Sinclair M, Hrudey S. Trichloroacetic acid as a biomarker of exposure to disinfection by-products in drinking water: a human exposure trial in Adelaide, Australia. Environ Health Perspect. 2002;110:679-87 pubmed
  34. Davison S. The prevalence and management of chronic pain in end-stage renal disease. J Palliat Med. 2007;10:1277-87 pubmed
  35. Profetto McGrath J, Smith K, Hugo K, Patel A, Dussault B. Nurse educators' critical thinking dispositions and research utilization. Nurse Educ Pract. 2009;9:199-208 pubmed publisher
    ..Education of nurse educators must include critical thinking to maximize their role in promoting research use as part of evidence-based practice. ..
  36. Mahadevan S, Shah S, Marrie T, Slupsky C. Analysis of metabolomic data using support vector machines. Anal Chem. 2008;80:7562-70 pubmed publisher
    ..We show that SVMs are superior to PLS-DA in both cases in terms of predictive accuracy with the least number of features. With fewer number of features, SVMs are able to give better predictive model when compared to that of PLS-DA. ..
  37. Menon D, Stafinski T. Engaging the public in priority-setting for health technology assessment: findings from a citizens' jury. Health Expect. 2008;11:282-93 pubmed publisher
    ..Citizens' juries offer a feasible approach to involving the public in priority-setting for HTA. Furthermore, technologies that may benefit a number of people and improve quality of life appear to be of greatest importance to the public. ..
  38. Chan A, McAlister F, Norris C, Johnstone D, Bakal J, Ross D. Effect of beta-blocker use on outcomes after discharge in patients who underwent cardiac surgery. J Thorac Cardiovasc Surg. 2010;140:182-7, 187.e1 pubmed publisher
    ..01). Patients discharged with beta-blockers after cardiac surgery exhibit a substantially lower mortality rate during long-term follow-up, even among those without a history of myocardial infarction or heart failure. ..
  39. Sharma S. Assessing diet and lifestyle in the Canadian Arctic Inuit and Inuvialuit to inform a nutrition and physical activity intervention programme. J Hum Nutr Diet. 2010;23 Suppl 1:5-17 pubmed publisher
    ..A further paper describes how these data were utilised to inform and develop Healthy Foods North. ..
  40. Karvellas C, McPhail M, Pink F, Asthana S, Muiesan P, Heaton N, et al. Bloodstream infection after elective liver transplantation is associated with increased mortality in patients with cirrhosis. J Crit Care. 2011;26:468-474 pubmed publisher
    ..7) was independently associated with mortality. Bloodstream infection post-LT was associated with increased severity of illness on admission, greater requirements for organ support, and increased mortality. ..
  41. Long R, Hoeppner V, Orr P, Ainslie M, King M, Abonyi S, et al. Marked disparity in the epidemiology of tuberculosis among Aboriginal peoples on the Canadian prairies: the challenges and opportunities. Can Respir J. 2013;20:223-30 pubmed
    ..The epidemiology of TB among Aboriginal peoples on the Canadian prairies is markedly disparate. Pulmonary TB is highly focal, which is both a concern and an opportunity. ..
  42. Poonja Z, Sobey A, Weinkauf J. Endobronchial hamartoma. J Bronchology Interv Pulmonol. 2013;20:247-8 pubmed publisher
    ..A polypectomy snare was effectively used with electrocautery to excise the lesion. The patient was successfully able to wean off the ventilator once the left lower lobe was free from obstruction. ..
  43. Yamaguchi T, Morita T, Nitto A, Takahashi N, Miyamoto S, Nishie H, et al. Establishing Cutoff Points for Defining Symptom Severity Using the Edmonton Symptom Assessment System-Revised Japanese Version. J Pain Symptom Manage. 2016;51:292-7 pubmed publisher
    ..The cutoff points established for determining the level of symptom severity using ESAS-r provides a guide for symptom management in Japanese cancer patients. ..
  44. Weismüller T, Trivedi P, Bergquist A, Imam M, Lenzen H, Ponsioen C, et al. Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis. Gastroenterology. 2017;152:1975-1984.e8 pubmed publisher
    ..The survival estimates provided might be used to estimate risk levels for patients with PSC and select patients for clinical trials. ..
  45. Tsui B, Gupta S, Finucane B. Detection of subarachnoid and intravascular epidural catheter placement. Can J Anaesth. 1999;46:675-8 pubmed
    ..The new test provides objective information in managing epidural catheters when their position is uncertain. ..
  46. McNeely M, Parliament M, Courneya K, Seikaly H, Jha N, Scrimger R, et al. A pilot study of a randomized controlled trial to evaluate the effects of progressive resistance exercise training on shoulder dysfunction caused by spinal accessory neurapraxia/neurectomy in head and neck cancer survivors. Head Neck. 2004;26:518-30 pubmed
    ..The preliminary findings, although limited, also suggest a potential therapeutic role for resistance exercise as an adjunct to standard physical therapy treatment. ..
  47. Prado C, Baracos V, McCargar L, Mourtzakis M, Mulder K, Reiman T, et al. Body composition as an independent determinant of 5-fluorouracil-based chemotherapy toxicity. Clin Cancer Res. 2007;13:3264-8 pubmed
    ..We conclude that variation in toxicity between females and males may be partially explained by this feature of body composition. ..
  48. Marrie T, Campbell N, McNeil S, Webster D, Hatchette T. Q fever update, Maritime Canada. Emerg Infect Dis. 2008;14:67-9 pubmed publisher
    ..Passive surveillance for Q fever in Nova Scotia and its neighboring provinces in eastern Canada indicates that the clinical manifestation of Q fever in the Maritime provinces is pneumonia and that incidence of the disease may fluctuate. ..
  49. Romanowski B, Myziuk L, Walmsley S, Trottier S, Singh A, Houston S, et al. Seroprevalence and risk factors for herpes simplex virus infection in a population of HIV-infected patients in Canada. Sex Transm Dis. 2009;36:165-9 pubmed publisher
    ..Knowledge of HSV serostatus would also provide an opportunity to consider antiviral therapy. ..
  50. Manuel O, Kumar D, Moussa G, Chen M, Pilewski J, McCurry K, et al. Lack of association between beta-herpesvirus infection and bronchiolitis obliterans syndrome in lung transplant recipients in the era of antiviral prophylaxis. Transplantation. 2009;87:719-25 pubmed publisher
    ..However, despite high viral loads in many patients, virus replication was not associated with the development of rejection or BOS. ..
  51. Karvellas C, Bagshaw S, McDermid R, Stollery D, Bain V, Gibney R. A case-control study of single-pass albumin dialysis for acetaminophen-induced acute liver failure. Blood Purif. 2009;28:151-8 pubmed publisher
    ..SPAD was well-tolerated in AALF; however, it was not associated with differences in clinical outcomes. While SPAD may be an adjuvant supportive therapy in AALF, prospective trials are needed. ..
  52. Eurich D, Sadowski C, Simpson S, Marrie T, Majumdar S. Recurrent community-acquired pneumonia in patients starting acid-suppressing drugs. Am J Med. 2010;123:47-53 pubmed publisher
    ..The association was confined to patients initiating PPI/H2s after hospital discharge. Our findings should be considered when deciding to prescribe these drugs in patients with a recent history of pneumonia. ..
  53. Padwal R, Klarenbach S, Wiebe N, Birch D, Karmali S, Manns B, et al. Bariatric surgery: a systematic review and network meta-analysis of randomized trials. Obes Rev. 2011;12:602-21 pubmed publisher
    ..Compared with Roux-en-Y gastric bypass, adjustable gastric banding has lower weight loss efficacy, but also leads to fewer serious adverse effects. ..
  54. Montano Loza A, Vargas Vorackova F, Ma M, Bain V, Burak K, Kumar T, et al. Incidence and risk factors associated with de novo autoimmune hepatitis after liver transplantation. Liver Int. 2012;32:1426-33 pubmed publisher
  55. Sapkota S, Wiebe S, Small B, Dixon R. Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults. Int J Geriatr Psychiatry. 2016;31:502-9 pubmed publisher
    ..Future research could target interactions of other personality traits and genetic polymorphisms in different clinical populations to predict other neurocognitive deficits or transitions to cognitive impairment and dementia. ..
  56. Boadu N, Amuasi J, Ansong D, Einsiedel E, Menon D, Yanow S. Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study. Malar J. 2016;15:126 pubmed publisher
    ..Clear, consistent guideline emphasis, with complementary action to address deep-rooted provider concerns will build their confidence in, and promote uptake of recommended policies, practices, and technology for diagnosing malaria. ..
  57. Russell L, Broderick G, Taylor R, Fernandes H, Harvey J, Barnes Z, et al. Illness progression in chronic fatigue syndrome: a shifting immune baseline. BMC Immunol. 2016;17:3 pubmed publisher
    ..These preliminary results suggest that IL-1α, 6 and 8 adjusted for illness duration may serve as robust biomarkers, independent of age, in screening for ME/CFS. ..
  58. Almansori M, Ijaz M, Ahmed S. Cerebral arrhythmia influencing cardiac rhythm: a case of ictal bradycardia. Seizure. 2006;15:459-61 pubmed
    ..We report a case of asymptomatic ictal bradycardia diagnosed during video EEG telemetry that was subsequently implanted with a cardiac pacemaker. ..
  59. Cheung J, Bailey R, Veldhuyzen van Zanten S, McLean R, Fedorak R, Morse J, et al. Early experience with unsedated ultrathin 4.9 mm transnasal gastroscopy: a pilot study. Can J Gastroenterol. 2008;22:917-22 pubmed
    ..Assuming the adverse event was a rare reaction, early experience with unsedated ultrathin transnasal gastroscopy was an efficient, effective and well-tolerated procedure for evaluation of the upper gastrointestinal tract. ..
  60. Thanh N, Wanke M, McGeachy L. Wait time from primary to specialty care: a trend analysis from Edmonton, Canada. Healthc Policy. 2013;8:35-44 pubmed
    ..additionally, specific opportunities for further improvement in referral wait time were noted. ..
  61. Pisansky T, Pugh S, Greenberg R, Pervez N, Reed D, Rosenthal S, et al. Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial. JAMA. 2014;311:1300-7 pubmed publisher
    ..These findings do not support daily use of tadalafil to prevent erectile dysfunction in these patients. Identifier: NCT00931528. ..
  62. Pederson J, Majumdar S, Forhan M, Johnson J, McAlister F. Current depressive symptoms but not history of depression predict hospital readmission or death after discharge from medical wards: a multisite prospective cohort study. Gen Hosp Psychiatry. 2016;39:80-5 pubmed publisher
    ..Depression was common, underrecognized and often persisted postdischarge. Current symptoms of depression, but not history, identified greater risk of short-term events independent of current risk prediction rules. ..
  63. Visser L, Dabbagh L, Poppema S. Reactivity of monoclonal antibody B-ly7 with a subset of activated T cells and T-cell lymphomas. Hematol Pathol. 1992;6:37-42 pubmed
    ..The results indicate that B-ly7 as well as HML-1 recognize an activation-associated antigen that is expressed on small normal T-cell and B-cell populations and can be induced on a relatively high proportion of T and B cells in vitro. ..
  64. Long R, Wong E, Barrie J. Bronchial anthracofibrosis and tuberculosis: CT features before and after treatment. AJR Am J Roentgenol. 2005;184:S33-6 pubmed
  65. Mullen J, Oreopoulos A, Lien D, Bentley M, Modry D, Stewart K, et al. A randomized, controlled trial of daclizumab vs anti-thymocyte globulin induction for lung transplantation. J Heart Lung Transplant. 2007;26:504-10 pubmed
    ..Significant infections were more frequent in the DZM group, but this was likely due to a higher incidence of CMV mismatch. Both methods of induction therapy worked well, with excellent 1-year survival. ..
  66. Peddle C, Au H, Courneya K. Associations between exercise, quality of life, and fatigue in colorectal cancer survivors. Dis Colon Rectum. 2008;51:1242-8 pubmed publisher
    ..Prospective observational studies and randomized, controlled trials are needed to further assess the causal nature of these relationships. ..
  67. Rowe B, Voaklander D, Wang D, Senthilselvan A, Klassen T, Marrie T, et al. Asthma presentations by adults to emergency departments in Alberta, Canada: a large population-based study. Chest. 2009;135:57-65 pubmed publisher
    ..Targeted interventions could be implemented to address specific groups and reduce asthma-related visits to Alberta EDs. ..
  68. Norris C, Ljubsa A, Hegadoren K. Gender as a determinant of responses to a self-screening questionnaire on anxiety and depression by patients with coronary artery disease. Gend Med. 2009;6:479-87 pubmed publisher
    ..In particular, the scale appears to be sensitive for measuring anxiety in women and depression in men. When the HADS is used clinically as a screening tool, it should be examined through a "gender-based lens.". ..
  69. Hwang J, Puttagunta L, Green F, Shimanovsky A, Barrie J, Long R. Bronchial anthracofibrosis and tuberculosis in immigrants to Canada from the Indian subcontinent. Int J Tuberc Lung Dis. 2010;14:231-7 pubmed
    ..Anthracofibrosis is not uncommon in immigrants to Canada from the Indian subcontinent with PTB. PTB may be a responsible or complicating condition in patients with anthracofibrosis. ..
  70. Martin L, Houston S, Yasui Y, Wild T, Saunders L. All-cause and HIV-related mortality rates among HIV-infected patients after initiating highly active antiretroviral therapy: the impact of Aboriginal ethnicity and injection drug use. Can J Public Health. 2011;102:90-6 pubmed
    ..Future research should examine reasons for the observed poorer survival of Aboriginal and IDU HIV patients after initiating HAART to develop interventions to improve the prognosis for these vulnerable populations. ..
  71. Sharma S, Wilkens L, Shen L, Kolonel L. Dietary sources of five nutrients in ethnic groups represented in the Multiethnic Cohort. Br J Nutr. 2013;109:1479-89 pubmed publisher
    ..Such data are valuable for identifying target foods for nutritional intervention programmes and directing public health strategies aimed at reducing dietary risk factors for chronic disease. ..
  72. Villeneuve P, Clark E, Sikora L, Sood M, Bagshaw S. Health-related quality-of-life among survivors of acute kidney injury in the intensive care unit: a systematic review. Intensive Care Med. 2016;42:137-46 pubmed publisher
    ..Importantly, the impaired HRQL was generally perceived as acceptable to patients, most of whom expressed willingness to undergo similar treatment in the future. ..
  73. Tsujimura T, Kuroda Y, Avila J, Kin T, Oberholzer J, Shapiro A, et al. Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method. Transplantation. 2004;78:96-100 pubmed
    ..There are time limitations for using the UW solution for pancreas preservation before human islet isolation. The TLM is a potential method to prolong the optimal cold storage time for successful islet isolations. ..
  74. Spratlin J, Sangha R, Glubrecht D, Dabbagh L, Young J, Dumontet C, et al. The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma. Clin Cancer Res. 2004;10:6956-61 pubmed
    ..Immunohistochemistry for hENT1 shows promise as a molecular predictive assay to appropriately select patients for palliative gemcitabine chemotherapy but requires formal validation in prospective, randomized trials. ..
  75. Noorbakhsh F, Tsutsui S, Vergnolle N, Boven L, Shariat N, Vodjgani M, et al. Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med. 2006;203:425-35 pubmed
    ..001) in WT animals. These findings reveal previously unreported pathogenic interactions between CNS PAR2 expression and neuroinflammation with ensuing demyelination and axonal injury. ..
  76. Pearson G, Francis G, Romney J, Gilchrist D, Opgenorth A, Gyenes G. The clinical effect and tolerability of ezetimibe in high-risk patients managed in a specialty cardiovascular risk reduction clinic. Can J Cardiol. 2006;22:939-45 pubmed
    ..The effect and tolerability of EZ among patients was evaluated in the clinical setting of a specialty cardiovascular risk reduction clinic at the University of Alberta Hospital, Edmonton, Alberta. patients and..
  77. Fairchild A, Goh P, Sinclair E, Barnes E, Ghosh S, Danjoux C, et al. Has the pattern of practice in the prescription of radiotherapy for the palliation of thoracic symptoms changed between 1999 and 2006 at the rapid response radiotherapy program?. Int J Radiat Oncol Biol Phys. 2008;70:693-700 pubmed publisher
    ..RT schedule for palliation of intrathoracic symptoms did not mirror the results of sequential, conflicting RCTs, suggesting that factors other than the literature influenced practice patterns in palliative thoracic RT. ..
  78. Jurasz P, Ng D, Granton J, Courtman D, Stewart D. Elevated platelet angiostatin and circulating endothelial microfragments in idiopathic pulmonary arterial hypertension: a preliminary study. Thromb Res. 2010;125:53-60 pubmed publisher
    ..These results are consistent with an increase in EC dysfunction in patients with IPAH, possibly contributing to the progression of IPAH and its associated thrombosis. ..
  79. Schulze C, Han L, Ghorpade N, Etches W, Stang L, Koshal A, et al. Phosphorylcholine-coated circuits improve preservation of platelet count and reduce expression of proinflammatory cytokines in CABG: a prospective randomized trial. J Card Surg. 2009;24:363-8 pubmed publisher
    ..Despite similar clinical outcome, the obvious reduction of cytokine expression and improved preservation of platelet count suggest superior biocompatibility of PC-coated circuits. ..
  80. Kaul P, Naylor C, Armstrong P, Mark D, Theroux P, Dagenais G. Assessment of activity status and survival according to the Canadian Cardiovascular Society angina classification. Can J Cardiol. 2009;25:e225-31 pubmed
    ..Despite its widespread use, limited data on the validity of the Canadian Cardiovascular Society angina (CCSA) classification relative to other measures of functional status have been reported...
  81. Morgan C, Zappitelli M, Gill P. Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review. Crit Care. 2009;13:R165 pubmed publisher
    ..This systematic review demonstrates that there is a significant gap that exists in the current literature in regards to the potential anti-inflammatory effect of statin therapy prior to CPB. ..
  82. Zhao L, Shields J, Tyrrell D. Functional changes, increased apoptosis, and diminished nuclear factor-kappaB activity of myeloid dendritic cells during chronic hepatitis C infection. Hum Immunol. 2010;71:751-62 pubmed publisher
    ..In conclusion, mDCs from CHC patients demonstrated functional changes with increased apoptosis, and diminished nuclear factor-kappaB activity. These changes may contribute to the impaired specific T-cell responses in CHC patients. ..
  83. Johnson J, Bowker S, Richardson K, Marra C. Time-varying incidence of cancer after the onset of type 2 diabetes: evidence of potential detection bias. Diabetologia. 2011;54:2263-71 pubmed publisher
    ..82, 95% CI 0.76, 0.88). People with type 2 diabetes are at increased risk of select cancers; this risk is particularly elevated at the time of diabetes onset, which is likely to be due to increased ascertainment. ..
  84. Lucchinetti E, Bestmann L, Feng J, Freidank H, Clanachan A, Finegan B, et al. Remote ischemic preconditioning applied during isoflurane inhalation provides no benefit to the myocardium of patients undergoing on-pump coronary artery bypass graft surgery: lack of synergy or evidence of antagonism in cardioprotection?. Anesthesiology. 2012;116:296-310 pubmed publisher
    ..001), but not with RIPC-induced changes in gene expression. RIPC applied during isoflurane inhalation provides no benefit to the myocardium of patients undergoing on-pump coronary artery bypass grafting. ..
  85. Sapkota Y, Robson P, Lai R, Cass C, Mackey J, Damaraju S. A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility. Eur J Hum Genet. 2012;20:682-9 pubmed publisher
    ..pombe), O-6-methylguanine-DNA methyltransferase and RNA polymerase II-associated protein 1. The identified markers may be relevant to breast cancer susceptibility in populations if these findings are confirmed in independent cohorts. ..
  86. Genuis S, Bouchard T. Combination of Micronutrients for Bone (COMB) Study: bone density after micronutrient intervention. J Environ Public Health. 2012;2012:354151 pubmed publisher
    ..This micronutrient regimen also appears to show efficacy in individuals where bisphosphonate therapy was previously unsuccessful in maintaining or raising BMD. Prospective clinical trials are required to confirm efficacy. ..
  87. Tonelli M, Muntner P, Lloyd A, Manns B, Klarenbach S, Pannu N, et al. Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study. Lancet. 2012;380:807-14 pubmed publisher
    ..Our findings suggest that chronic kidney disease could be added to the list of criteria defining people at highest risk of future coronary events. Alberta Heritage Foundation for Medical Research. ..
  88. Fairchild A, Debenham B, Danielson B, Huang F, Ghosh S. Comparative multidisciplinary prediction of survival in patients with advanced cancer. Support Care Cancer. 2014;22:611-7 pubmed publisher
    ..KPS was the only significant variable on multivariate analysis (p???0.04). MDT members providing collaborative care for advanced cancer patients utilize similar factors in predicting survival with comparable accuracy. ..
  89. Gnidehou S, Doritchamou J, Arango E, Cabrera A, Arroyo M, Kain K, et al. Functional antibodies against VAR2CSA in nonpregnant populations from colombia exposed to Plasmodium falciparum and Plasmodium vivax. Infect Immun. 2014;82:2565-73 pubmed publisher
    ..falciparum or P. vivax infection outside pregnancy. These findings may hold significant clinical relevance to the pathophysiology and outcome of malaria infections in this region. ..
  90. Bland J, Ashworth N. Does prior local corticosteroid injection prejudice the outcome of subsequent carpal tunnel decompression?. J Hand Surg Eur Vol. 2016;41:130-6 pubmed publisher
    ..Post-operative symptom severity and functional status scores showed no significant difference between the direct-to-surgery and prior-injection groups. Prior local steroid injection does not prejudice the outcome of surgery. IV. ..
  91. Liu X, Bell C, Simmonds K, Svenson L, Russell M. Adverse events following HPV vaccination, Alberta 2006-2014. Vaccine. 2016;34:1800-5 pubmed publisher
    ..Rates of AEFI after HPV immunization in Alberta are low and consistent with types of events seen elsewhere. ..
  92. Terada T, Wilson B, Myette Cόté E, Kuzik N, Bell G, McCargar L, et al. Targeting specific interstitial glycemic parameters with high-intensity interval exercise and fasted-state exercise in type 2 diabetes. Metabolism. 2016;65:599-608 pubmed publisher
    ..Performing HIIE under fasted condition may be most advantageous as it lowered most aspects of glycemia. ..