Experts and Doctors on zebrafish in Liège, Wallonia, Belgium

Summary

Locale: Liège, Wallonia, Belgium
Topic: zebrafish

Top Publications

  1. Detry B, Erpicum C, Paupert J, Blacher S, Maillard C, Bruyére F, et al. Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase. Blood. 2012;119:5048-56 pubmed publisher
    ..Our findings provide new mechanistic insight into how LECs negotiate an interstitial type I collagen barrier and reveal an unexpected MMP2-driven collagenolytic pathway for lymphatic vessel formation and morphogenesis. ..
  2. Pruvot B, Quiroz Y, Voncken A, Jeanray N, Piot A, Martial J, et al. A panel of biological tests reveals developmental effects of pharmaceutical pollutants on late stage zebrafish embryos. Reprod Toxicol. 2012;34:568-83 pubmed publisher
    ..Our results allow us to compare various toxicological endpoints and may contribute to the design of a rational high throughput approach using the zebrafish model. ..
  3. Dalcq J, Pasque V, Ghaye A, Larbuisson A, Motte P, Martial J, et al. RUNX3, EGR1 and SOX9B form a regulatory cascade required to modulate BMP-signaling during cranial cartilage development in zebrafish. PLoS ONE. 2012;7:e50140 pubmed publisher
  4. Flasse L, Pirson J, Stern D, Von Berg V, Manfroid I, Peers B, et al. Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biol. 2013;11:78 pubmed publisher
    ..It is repressed by Notch signaling that prevents pancreatic cell differentiation by maintaining precursors in an undifferentiated state...
  5. Pruvot B, Curé Y, Djiotsa J, Voncken A, Muller M. Developmental defects in zebrafish for classification of EGF pathway inhibitors. Toxicol Appl Pharmacol. 2014;274:339-49 pubmed publisher
    ..In conclusion, we show that developmental indicators can help to discriminate between specific effects on the target pathway from off-target effects in molecularly targeted drug screening experiments in whole animal systems. ..
  6. Ledoux A, St Gelais A, Cieckiewicz E, Jansen O, Bordignon A, Illien B, et al. Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of Poupartia borbonica. J Nat Prod. 2017;80:1750-1757 pubmed publisher
    ..This extract contained the known flavonoids, quercetin, 3'-O-hydroxysulfonylquercetin, quercitrin, and isoquercitrin as well as ellagic acid, which showed high to low activity against the 3D7 P. falciparum strain. ..
  7. Joris M, Schloesser M, Baurain D, Hanikenne M, Muller M, Motte P. Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors. Nucleic Acids Res. 2017;45:9547-9557 pubmed publisher
    ..Our data contribute to the debate about MO specificity, efficacy and the number of unknown targeted sequences. ..