Experts and Doctors on humans in Gembloux, Wallonia, Belgium


Locale: Gembloux, Wallonia, Belgium
Topic: humans

Top Publications

  1. Frederickx C, Dekeirsschieter J, Verheggen F, Haubruge E. Responses of Lucilia sericata Meigen (Diptera: Calliphoridae) to cadaveric volatile organic compounds. J Forensic Sci. 2012;57:386-90 pubmed publisher
    ..sericata, while the other VOCs are repulsive or do not cause any behavior. Our results may have potential implications in a better understanding of attractiveness of blowflies toward a corpse. ..
  2. Tungu P, Kirby M, Malima R, Kisinza W, Magesa S, Maxwell C, et al. Interceptor® long-lasting insecticidal net: phase III evaluation over three years of household use and calibration with Phase II experimental hut outcomes. Parasit Vectors. 2016;9:204 pubmed publisher
    ..More than 80% Interceptor LN fulfilled the WHOPES Phase III criteria at 36 months and thus the LLIN was granted full WHO recommendation. Phase III outcomes at 36 months were anticipated by Phase II outcomes after 20 standardized washes. ..
  3. Massue D, Moore S, Mageni Z, Moore J, Bradley J, Pigeon O, et al. Durability of Olyset campaign nets distributed between 2009 and 2011 in eight districts of Tanzania. Malar J. 2016;15:176 pubmed publisher
    ..However, the majority of nets still retained substantial levels of permethrin and could still be bio-chemically useful against mosquitoes if their holes were repaired, adding evidence to the value of net care and repair campaigns. ..
  4. Riou M, Avrain L, Carbonnelle S, El Garch F, Pirnay J, De Vos D, et al. Increase of efflux-mediated resistance in Pseudomonas aeruginosa during antibiotic treatment in patients suffering from nosocomial pneumonia. Int J Antimicrob Agents. 2016;47:77-83 pubmed publisher
    ..Overexpression of genes encoding antibiotic transporters in P. aeruginosa during treatment is frequent and is associated with increases in MICs above EUCAST clinical susceptibility breakpoints. ..
  5. Hubaux R, Vandermeers F, Crisanti M, Crisanti C, Kapoor V, Burny A, et al. Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy. Eur J Cancer. 2010;46:1724-34 pubmed publisher
    ..Together, these data demonstrate that VPA augments anticancer activity of cisplatin and etoposide, two components of the standard first-line chemotherapy of small cell lung cancer. ..
  6. Vandeplas S, Dubois Dauphin R, Beckers Y, Thonart P, Thewis A. Salmonella in chicken: current and developing strategies to reduce contamination at farm level. J Food Prot. 2010;73:774-85 pubmed
    ..Other control methods such as the use of chlorate products and bacteriophages also are under study. ..
  7. Abdel Massih M, Planchon V, Polet M, Dierick K, Mahillon J. Analytical performances of food microbiology laboratories - critical analysis of 7 years of proficiency testing results. J Appl Microbiol. 2016;120:346-54 pubmed publisher
  8. Lins L, Decaffmeyer M, Thomas A, Brasseur R. Relationships between the orientation and the structural properties of peptides and their membrane interactions. Biochim Biophys Acta. 2008;1778:1537-44 pubmed publisher
  9. Martin M, Potente M, Janssens V, Vertommen D, Twizere J, Rider M, et al. Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis. Proc Natl Acad Sci U S A. 2008;105:4727-32 pubmed publisher
    ..This study unravels a dynamic interplay among 14-3-3s, protein kinases, and PP2A and provides a model for the regulation of class IIa HDACs. ..

More Information


  1. Dekeirsschieter J, Stefanuto P, Brasseur C, Haubruge E, Focant J. Enhanced characterization of the smell of death by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GCxGC-TOFMS). PLoS ONE. 2012;7:e39005 pubmed publisher
    ..The use of GCxGC-TOFMS in study of postmortem volatile compounds instead of conventional GC-MS was successful. ..
  2. Legros S, Boxus M, Gatot J, Van Lint C, Kruys V, Kettmann R, et al. The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6. Oncogene. 2011;30:4050-62 pubmed publisher
    ..We postulate that inhibition of the stress response pathway by Tax would favor cell survival under stressful conditions and may have an important role in HTLV-1-induced cellular transformation. ..
  3. Verheggen F, Haubruge E, Mescher M. Alarm pheromones-chemical signaling in response to danger. Vitam Horm. 2010;83:215-39 pubmed publisher
    ..We conclude with a brief discussion of the potential exploitation of alarm signaling to achieve the applied goal of managing pest species. ..
  4. Zirbes L, Nguyen B, de Graaf D, De Meulenaer B, Reybroeck W, Haubruge E, et al. Hydroxymethylfurfural: a possible emergent cause of honey bee mortality?. J Agric Food Chem. 2013;61:11865-70 pubmed publisher
    ..This paper reviews the current knowledge of the presence of HMF in honey bee environment and possible consequences on bee mortality. Some lines of inquiry for further toxicological analysis are likewise proposed. ..
  5. Willems L. The 14th International Conference on Human Retrovirology: HTLV and related retroviruses (July 1-4, 2009; Salvador, Brazil). Retrovirology. 2009;6:77 pubmed publisher
    ..Exciting new findings were presented in these different fields, and the new advances have led to novel clinical trials. Here, highlights from this conference are summarized...
  6. Vandermeers F, Hubert P, Delvenne P, Mascaux C, Grigoriu B, Burny A, et al. Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma. Clin Cancer Res. 2009;15:2818-28 pubmed publisher
    ..These observations support the potential additional efficacy of valproate in combination with pemetrexed and cisplatin for treatment of malignant mesothelioma. ..
  7. Bouzar A, Willems L. How HTLV-1 may subvert miRNAs for persistence and transformation. Retrovirology. 2008;5:101 pubmed publisher
    ..The pathways modulated by these described miRNAs are critically involved in apoptosis, proliferation and innate immune response...
  8. Boxus M, Twizere J, Legros S, Dewulf J, Kettmann R, Willems L. The HTLV-1 Tax interactome. Retrovirology. 2008;5:76 pubmed publisher
    ..In this review, we summarize the present knowledge of the Tax1 interactome and propose a rationale for the broad range of cellular proteins identified so far...
  9. Gillet N, Florins A, Boxus M, Burteau C, Nigro A, Vandermeers F, et al. Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human. Retrovirology. 2007;4:18 pubmed
    ..Recently, the BLV model has also cast light onto novel prospects for therapies of HTLV induced diseases, for which no satisfactory treatment exists so far...
  10. Thomas A, Allouche M, Basyn F, Brasseur R, Kerfelec B. Role of the lid hydrophobicity pattern in pancreatic lipase activity. J Biol Chem. 2005;280:40074-83 pubmed
  11. Twizere J, Lefebvre L, Collete D, Debacq C, Urbain P, Heremans H, et al. The homeobox protein MSX2 interacts with tax oncoproteins and represses their transactivation activity. J Biol Chem. 2005;280:29804-11 pubmed
    ..And interestingly, MSX2 also interacts with and inhibits the transactivation function of the related Tax1 protein encoded by the Human T-cell leukemia virus type 1 (HTLV-1)...
  12. Claes V, Kettmann R, Burny A. Structure of the gene encoding pig phosphoglucose isomerase. Gene. 1994;150:235-41 pubmed
    ..Extending from the 5'-flanking region to the first intron, a 0.6-kb CpG island has been identified. The Pgi structural gene contains several DNA repetitive elements in its non-coding regions. ..
  13. Toumi K, Joly L, Vleminckx C, Schiffers B. Risk Assessment of Florists Exposed to Pesticide Residues through Handling of Flowers and Preparing Bouquets. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..Therefore the priority should be to raise the level of awareness among the florists who must change their habits and practices if they want to minimize their exposure. ..
  14. Sneyers M, Kettmann R, Massart S, Renaville R, Burny A, Portetelle D. Cloning and characterization of a cDNA encoding the bovine insulin-like growth factor binding protein 1 (bIGFBP-1). DNA Seq. 1991;1:407-8 pubmed
    ..This communication reports the complete amino acid sequence (263 amino acids) for the insulin-like growth factor binding protein 1 in the bovine (bIGFBP-1). It is 70% homologous with the equivalent IGFBP-1 in human and rat. ..
  15. Sneyers M, Kettmann R, Massart S, Renaville R, Burny A, Portetelle D. Cloning and characterization of a cDNA encoding the beta-subunit of the bovine insulin-like growth factor-1 receptor. DNA Seq. 1991;1:405-6 pubmed
    ..This communication reports the sequence of the beta-subunit of the insulin-like growth factor-1 receptor. It shares 91.1% homology at the nucleotide level and 97.7% at the amino acid level with the equivalent human receptor subunit. ..
  16. Rey C, Vanderschuren H. Cassava Mosaic and Brown Streak Diseases: Current Perspectives and Beyond. Annu Rev Virol. 2017;4:429-452 pubmed publisher
    ..This review explores established and new technologies for genetic manipulation to achieve desired traits such as virus resistance. ..
  17. Boxus M, Willems L. Mechanisms of HTLV-1 persistence and transformation. Br J Cancer. 2009;101:1497-501 pubmed publisher
    ..HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong immune response. In this review, we summarise these mechanisms and their contribution to T-cell transformation and ATL development...
  18. Dequiedt F, Martin M, von Blume J, Vertommen D, Lecomte E, Mari N, et al. New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases. Mol Cell Biol. 2006;26:7086-102 pubmed
    ..e., Ser155, is a prerequisite for the phosphorylation of the nearby 14-3-3 site, Ser181. We propose that this multisite hierarchical phosphorylation by a variety of kinases allows for sophisticated regulation of class IIa HDACs function. ..
  19. Twizere J, Kruys V, Lef bvre L, Vanderplasschen A, Collete D, Debacq C, et al. Interaction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression. J Natl Cancer Inst. 2003;95:1846-59 pubmed
    ..This observation is of importance for the cell transformation process induced by leukemogenic retroviruses, because TNF-alpha overexpression plays a central role in pathogenesis...
  20. Gatot J, Callebaut I, Van Lint C, Demonte D, Kerkhofs P, Portetelle D, et al. Bovine leukemia virus SU protein interacts with zinc, and mutations within two interacting regions differently affect viral fusion and infectivity in vivo. J Virol. 2002;76:7956-67 pubmed
  21. Lefebvre L, Vanderplasschen A, Ciminale V, Heremans H, Dangoisse O, Jauniaux J, et al. Oncoviral bovine leukemia virus G4 and human T-cell leukemia virus type 1 p13(II) accessory proteins interact with farnesyl pyrophosphate synthetase. J Virol. 2002;76:1400-14 pubmed
    ..Identification of FPPS as a molecular partner for p13(II) and G4 accessory proteins opens new prospects for treatment of retrovirus-induced leukemia...
  22. Dequiedt F, Kettmann R, Burny A, Willems L. Nucleotide sequence of the ovine P53 tumor-suppressor cDNA and its genomic organization. DNA Seq. 1995;5:255-9 pubmed
    ..We also report the structure of the ovine p53 gene that is similar to those already defined from other species. ..
  23. Yu Q, Reichert M, Brousseau T, Cleuter Y, Burny A, Kettmann R. Sequence of bovine CD5. Nucleic Acids Res. 1990;18:5296 pubmed