Experts and Doctors on hela cells in Gembloux, Wallonia, Belgium

Summary

Locale: Gembloux, Wallonia, Belgium
Topic: hela cells

Top Publications

  1. Lefebvre L, Vanderplasschen A, Ciminale V, Heremans H, Dangoisse O, Jauniaux J, et al. Oncoviral bovine leukemia virus G4 and human T-cell leukemia virus type 1 p13(II) accessory proteins interact with farnesyl pyrophosphate synthetase. J Virol. 2002;76:1400-14 pubmed
    ..Identification of FPPS as a molecular partner for p13(II) and G4 accessory proteins opens new prospects for treatment of retrovirus-induced leukemia...
  2. Twizere J, Lefebvre L, Collete D, Debacq C, Urbain P, Heremans H, et al. The homeobox protein MSX2 interacts with tax oncoproteins and represses their transactivation activity. J Biol Chem. 2005;280:29804-11 pubmed
    ..And interestingly, MSX2 also interacts with and inhibits the transactivation function of the related Tax1 protein encoded by the Human T-cell leukemia virus type 1 (HTLV-1)...
  3. Legros S, Boxus M, Gatot J, Van Lint C, Kruys V, Kettmann R, et al. The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6. Oncogene. 2011;30:4050-62 pubmed publisher
    ..We postulate that inhibition of the stress response pathway by Tax would favor cell survival under stressful conditions and may have an important role in HTLV-1-induced cellular transformation. ..
  4. Dequiedt F, Martin M, von Blume J, Vertommen D, Lecomte E, Mari N, et al. New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases. Mol Cell Biol. 2006;26:7086-102 pubmed
    ..e., Ser155, is a prerequisite for the phosphorylation of the nearby 14-3-3 site, Ser181. We propose that this multisite hierarchical phosphorylation by a variety of kinases allows for sophisticated regulation of class IIa HDACs function. ..