Experts and Doctors on male in Vienna, Austria


Locale: Vienna, Austria
Topic: male

Top Publications

  1. Gracia Marco L, Bel Serrat S, Cuenca Garcia M, Gonzalez Gross M, Pedrero Chamizo R, Manios Y, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49:1041-1052 pubmed publisher
    ..In conclusion, we failed to detect any associations between any of the evaluated AAs and physical fitness after taking into account the effect of multiple testing. ..
  2. Häfner J, Ginner L, Karst S, Leitgeb R, Unterluggauer M, Sacu S, et al. Regional Patterns of Retinal Oxygen Saturation and Microvascular Hemodynamic Parameters Preceding Retinopathy in Patients With Type II Diabetes. Invest Ophthalmol Vis Sci. 2017;58:5541-5547 pubmed publisher
    ..The purpose of this study was to investigate if retinal oxygen saturation (SO2) and microvascular hemodynamic parameters follow a distinct regional pattern in patients with diabetes but no DR...
  3. Kammerlander A, Aschauer S, Zotter Tufaro C, Duca F, Knechtelsdorfer K, Wiesinger M, et al. Diameter of the Pulmonary Artery in Relation to the Ascending Aorta: Association with Cardiovascular Outcome. Radiology. 2017;284:685-693 pubmed publisher
    ..On the basis of these results, the PA-to-Ao ratio should routinely be reported at cardiac MR imaging. © RSNA, 2017 Online supplemental material is available for this article. ..
  4. Allard M, Adam R, Giuliante F, Lapointe R, Hubert C, Ijzermans J, et al. Long-term outcomes of patients with 10 or more colorectal liver metastases. Br J Cancer. 2017;117:604-611 pubmed publisher
    ..Liver resection might provide long-term survival in patients with ⩾10 CLM staged with preoperative MRI, provided R0/R1 resection followed by adjuvant therapy. A validation of these results in another cohort is needed. ..
  5. Herter Aeberli I, Eliancy K, Rathon Y, Loechl C, Marhône Pierre J, Zimmermann M. In Haitian women and preschool children, iron absorption from wheat flour-based meals fortified with sodium iron EDTA is higher than that from meals fortified with ferrous fumarate, and is not affected by Helicobacter pylori infection in children. Br J Nutr. 2017;118:273-279 pubmed publisher
    ..In the context of Haiti, where the high costs of NaFeEDTA may not be affordable, the use of FeFum at 60 mg Fe/kg flour may be a preferable, cost-effective fortification strategy. ..
  6. Brunner M, Jagannathan V, Waluk D, Roosje P, Linek M, Panakova L, et al. Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X. PLoS ONE. 2017;12:e0186469 pubmed publisher
    ..These findings are in agreement with the so far proposed but not yet proven deregulation of the sex hormone metabolism in this disease...
  7. Kumar S, Moreau P, Hari P, Mateos M, Ludwig H, Shustik C, et al. Management of adverse events associated with ixazomib plus lenalidomide/dexamethasone in relapsed/refractory multiple myeloma. Br J Haematol. 2017;178:571-582 pubmed publisher
    ..Most toxicities were manageable with supportive care and dose delays or reductions as needed. Clinicians should be aware of and understand these potential side effects to optimise and prolong patient benefit. ..
  8. Haj Najeeb B, Simader C, Deak G, Vass C, Gamper J, Montuoro A, et al. The Distribution of Leakage on Fluorescein Angiography in Diabetic Macular Edema: A New Approach to Its Etiology. Invest Ophthalmol Vis Sci. 2017;58:3986-3990 pubmed publisher
    ..Moreover, fluid extravasation due to damage to the iBRB is expressed earlier in the temporal than in the other three fields. ..
  9. Nöbauer T, Skocek O, Pernía Andrade A, Weilguny L, Traub F, Molodtsov M, et al. Video rate volumetric Ca2+ imaging across cortex using seeded iterative demixing (SID) microscopy. Nat Methods. 2017;14:811-818 pubmed publisher
    ..We expect that the simplicity and scalability of LFM, coupled with the performance of SID, will open up a range of applications including closed-loop experiments. ..

More Information

Publications123 found, 100 shown here

  1. Wolthers B, Frandsen T, Baruchel A, Attarbaschi A, Barzilai S, Colombini A, et al. Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study. Lancet Oncol. 2017;18:1238-1248 pubmed publisher
    ..A study of the genetic risk factors identifying patients in whom asparaginase exposure should be restricted is needed. The Danish Childhood Cancer Foundation and The Danish Cancer Society (R150-A10181). ..
  2. Getachew T, Huson H, Wurzinger M, Burgstaller J, Gizaw S, Haile A, et al. Identifying highly informative genetic markers for quantification of ancestry proportions in crossbred sheep populations: implications for choosing optimum levels of admixture. BMC Genet. 2017;18:80 pubmed publisher
  3. Gabriel M, Kruger R, Shams Mafi F, Hermann B, Zabihian B, Schmetterer L, et al. Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017;58:4778-4783 pubmed publisher
    ..To analyze retinal thickness (RT) and choroidal thickness (ChT) changes in patients with unilateral nongranulomatous acute anterior uveitis (AAU) using three-dimensional (3D) 1060-nm optical coherence tomography (OCT)...
  4. Falkensammer J, Taher F, Uhlmann M, Hirsch K, Strassegger J, Assadian A. Rescue of failed endovascular aortic aneurysm repair using the fenestrated Anaconda device. J Vasc Surg. 2017;66:1334-1339 pubmed publisher
    ..As a consequence, fenestrations may not line up perfectly at the respective openings of the visceral or renal arteries, and folding of the fabric may be increased, making cannulation of the fenestrations more difficult. ..
  5. Guedes de Castro D, Matiello J, Roa W, Ghosh S, Kepka L, Kumar N, et al. Survival Outcomes With Short-Course Radiation Therapy in Elderly Patients With Glioblastoma: Data From a Randomized Phase 3 Trial. Int J Radiat Oncol Biol Phys. 2017;98:931-938 pubmed publisher
  6. Fan A. The methodology flaws in Hinman's acupuncture clinical trial, Part II: Zelen design and effectiveness dilutions. J Integr Med. 2015;13:136-9 pubmed publisher
  7. Jellinger K, Paulus W, Grundke Iqbal I, Riederer P, Youdim M. Brain iron and ferritin in Parkinson's and Alzheimer's diseases. J Neural Transm Park Dis Dement Sect. 1990;2:327-40 pubmed
  8. Ferenci P, Fried M, LaBrecque D, Bruix J, Sherman M, Omata M, et al. Hepatocellular carcinoma (HCC): a global perspective. J Clin Gastroenterol. 2010;44:239-45 pubmed publisher
  9. Holzer M. Targeted temperature management for comatose survivors of cardiac arrest. N Engl J Med. 2010;363:1256-64 pubmed publisher
  10. Zweiker D, Maier R, Lamm G, Maurer E, Heigert M, Neunteufl T, et al. The Austrian transcatheter aortic valve implantation (TAVI) Registry--3 years' data. Int J Cardiol. 2014;177:114-6 pubmed publisher
  11. Hobl E, Jilma B. Towards the development of specific antidotes: Idarucizumab for reversal of dabigatran effects. Thromb Haemost. 2015;113:1162-3 pubmed publisher
  12. Dimopoulos M, Stewart A, Masszi T, Spicka I, Oriol A, Hajek R, et al. Carfilzomib, lenalidomide, and dexamethasone in patients with relapsed multiple myeloma categorised by age: secondary analysis from the phase 3 ASPIRE study. Br J Haematol. 2017;177:404-413 pubmed publisher
    ..Carfilzomib-lenalidomide-dexamethasone has a favourable benefit-risk profile for patients with RMM, including elderly patients ?70 years old. identifier: NCT01080391. ..
  13. Posch F, Gebhart J, Rand J, Koder S, Quehenberger P, Pengo V, et al. Cardiovascular risk factors are major determinants of thrombotic risk in patients with the lupus anticoagulant. BMC Med. 2017;15:54 pubmed publisher
  14. Daver N, McClain K, Allen C, Parikh S, Otrock Z, Rojas Hernandez C, et al. A consensus review on malignancy-associated hemophagocytic lymphohistiocytosis in adults. Cancer. 2017;123:3229-3240 pubmed publisher
    ..Cancer 2017;123:3229-40. © 2017 American Cancer Society. ..
  15. D ANDREA D, Moschini M, Soria F, Gust K, Briganti A, Karakiewicz P, et al. ABO Blood Group and Rhesus Factor Are Not Associated with Outcomes After Radical Cystectomy for Non-metastatic Urothelial Carcinoma of the Bladder. Anticancer Res. 2017;37:5747-5753 pubmed
    ..To investigate the role of ABO blood group and Rhesus factor as a predictor of outcome in patients undergoing radical cystectomy (RC) for non-metastatic urothelial carcinoma of the bladder...
  16. Bonderman D, Pretsch I, Steringer Mascherbauer R, Jansa P, Rosenkranz S, Tufaro C, et al. Acute hemodynamic effects of riociguat in patients with pulmonary hypertension associated with diastolic heart failure (DILATE-1): a randomized, double-blind, placebo-controlled, single-dose study. Chest. 2014;146:1274-1285 pubmed publisher
    ..In patients with HFpEF and PH, riociguat was well tolerated, had no significant effect on mPAP, and improved exploratory hemodynamic and echocardiographic parameters.; No.: NCT01172756; URL: ..
  17. Regitz Zagrosek V, Oertelt Prigione S, Prescott E, Franconi F, Gerdts E, Foryst Ludwig A, et al. Gender in cardiovascular diseases: impact on clinical manifestations, management, and outcomes. Eur Heart J. 2016;37:24-34 pubmed publisher
  18. Zatorska B, Groger M, Moser D, Diab Elschahawi M, Lusignani L, Presterl E. Does Extracellular DNA Production Vary in Staphylococcal Biofilms Isolated From Infected Implants versus Controls?. Clin Orthop Relat Res. 2017;475:2105-2113 pubmed publisher
    ..eDNA should be considered as a potential future diagnostic tool or even a possible target to modify biofilms for successful treatment of biofilm-associated infections. ..
  19. Smirnov I, Thurner S. Formation of homophily in academic performance: Students change their friends rather than performance. PLoS ONE. 2017;12:e0183473 pubmed publisher
    ..The lack of a social pull effect in classical educational settings could have important implications for the understanding of the observed persistence of segregation, inequality and social immobility in societies...
  20. Dell Oglio P, Stabile A, Gandaglia G, Zaffuto E, Fossati N, Bandini M, et al. New surgical approaches for clinically high-risk or metastatic prostate cancer. Expert Rev Anticancer Ther. 2017;17:1013-1031 pubmed publisher
    ..In consequence, longer follow-up data and, ideally, randomized controlled trials are needed. ..
  21. Baron Stefaniak J, Schiefer J, Miller E, Berlakovich G, Baron D, Faybik P. Comparison of macrophage migration inhibitory factor and neutrophil gelatinase-associated lipocalin-2 to predict acute kidney injury after liver transplantation: An observational pilot study. PLoS ONE. 2017;12:e0183162 pubmed publisher
    ..53-0.88; P = 0.03), and urinary NGAL (AUC 0.79; CI 0.64-0.93; P = 0.02) were predictive for severe AKI, while serum NGAL was not. In the setting of OLT, MIF and NGAL had similar predictive values for the development of severe AKI. ..
  22. Weissenbacher Lang C, Nedorost N, Knecht C, Hennig Pauka I, Hüber M, Voglmayr T, et al. Comparison of Pneumocystis nucleic acid and antibody profiles and their associations with other respiratory pathogens in two Austrian pig herds. PLoS ONE. 2017;12:e0185387 pubmed publisher
    ..Younger pigs may be more susceptible as they had higher PCS burdens. It is possible that PCS may contribute to a respiratory disease in pigs and further investigation of its potential role is warranted. ..
  23. Haslacher H, Ratzinger F, Perkmann T, Batmyagmar D, Nistler S, Scherzer T, et al. A combination of routine blood analytes predicts fitness decrement in elderly endurance athletes. PLoS ONE. 2017;12:e0177174 pubmed publisher
    ..It hence merits further research whether these conclusions can be translated to other disciplines or age groups. ..
  24. Watzinger F, Birkfellner W, Wanschitz F, Millesi W, Schopper C, Sinko K, et al. Positioning of dental implants using computer-aided navigation and an optical tracking system: case report and presentation of a new method. J Craniomaxillofac Surg. 1999;27:77-81 pubmed
    ..The experience gained in this intervention led to the conclusion that computer-aided surgery provides a valuable tool in implant dentistry. ..
  25. Shelton J, Hertz Picciotto I. Neurodevelopmental disorders and agricultural pesticide exposures: Shelton and Hertz-Picciotto respond. Environ Health Perspect. 2015;123:A79-80 pubmed publisher
  26. Stadelmann C, Deckwerth T, Srinivasan A, Bancher C, Bruck W, Jellinger K, et al. Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death. Am J Pathol. 1999;155:1459-66 pubmed
  27. Sato T, Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, et al. ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage. Cardiovasc Res. 2017;113:760-769 pubmed publisher
    ..The different effects of ELA and Apelin on the expression of ACE and ACE2 implicate fine-tuned mechanisms for a ligand-induced APJ activation and downstream signalling. ..
  28. Serruys P, Katagiri Y, Sotomi Y, Zeng Y, Chevalier B, van der Schaaf R, et al. Arterial Remodeling After Bioresorbable Scaffolds and Metallic Stents. J Am Coll Cardiol. 2017;70:60-74 pubmed publisher
    ..ABSORB II Randomized Controlled Trial; NCT01425281). ..
  29. Feist E, Steiner G. Rheumatoid arthritis: an antigenic chameleon. Ann Rheum Dis. 2014;73:1753-4 pubmed publisher
  30. Vastesaeger N, Fautrel B, Smolen J. Response to 'Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis'. Arthritis Res Ther. 2015;17:166 pubmed publisher
  31. Brandao L, Monhart M, Schotzau A, Ledolter A, Palmowski Wolfe A. Wavelet decomposition analysis in the two-flash multifocal ERG in early glaucoma: a comparison to ganglion cell analysis and visual field. Doc Ophthalmol. 2017;135:29-42 pubmed publisher
    ..mfERG using WVA analysis improves glaucoma diagnosis, especially when combined with GCIPL and MS. ..
  32. Drexel M, Romanov R, Wood J, Weger S, Heilbronn R, Wulff P, et al. Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice. J Neurosci. 2017;37:8166-8179 pubmed publisher
    ..The experiments highlight the importance of the potent inhibitory action mediated by parvalbumin cells in the hippocampus and identify a potential mechanism in the development of TLE. ..
  33. Baradaran Ghahfarokhi M, Amouheidari A, Shahbazi Gahrouei D, Baradaran Ghahfarokhi H, Tanderup K, Dörr W, et al. Evaluation of the Effects of Prostate Radiation Therapy on Occludin Expression and Ultrasonography Characteristics of the Bladder. Int J Radiat Oncol Biol Phys. 2017;99:963-971 pubmed publisher
    ..Our findings suggest that a significant reduction in bladder echogenicity and increase in occludin expression during treatment can be associated with acute urinary complications. ..
  34. Emminger W, Hernández M, Cardona V, Smeenk F, Fogh B, Calderon M, et al. The SQ House Dust Mite SLIT-Tablet Is Well Tolerated in Patients with House Dust Mite Respiratory Allergic Disease. Int Arch Allergy Immunol. 2017;174:35-44 pubmed publisher
    ..42). The SQ HDM SLIT-tablet is well tolerated, and the safety profile was comparable for subjects with HDM respiratory allergic disease irrespective of asthma status. ..
  35. Wielscher M, Vierlinger K, Kegler U, Ziesche R, Gsur A, Weinhäusel A. Diagnostic Performance of Plasma DNA Methylation Profiles in Lung Cancer, Pulmonary Fibrosis and COPD. EBioMedicine. 2015;2:929-36 pubmed publisher
    ..72-0.95). This technique was capable of distinguishing interrelated complex pulmonary diseases suggesting that multiplexed MSRE enrichment might be useful for simple and reliable diagnosis of diverse multifactorial disease states. ..
  36. Mattiassich G, Rittenschober F, Dorninger L, Rois J, Mittermayr R, Ortmaier R, et al. Long-term outcome following upper extremity replantation after major traumatic amputation. BMC Musculoskelet Disord. 2017;18:77 pubmed publisher
    ..In addition, all participants were very satisfied with their outcomes. Positive long-term results with high rates of subjective satisfaction are possible after replantation of upper extremities. ..
  37. Sayegh R, Sacu S, Dunavölgyi R, Kroh M, Roberts P, Mitsch C, et al. Geographic Atrophy and Foveal-Sparing Changes Related to Visual Acuity in Patients With Dry Age-Related Macular Degeneration Over Time. Am J Ophthalmol. 2017;179:118-128 pubmed publisher
    ..In general, FS highly correlated with BCVA, while GA progression correlated with the central 3-mm FS regression, but not with BCVA. A threshold in GA and FS area could be determined for BCVA necessary for daily activity. ..
  38. Tscharre M, Egger F, Machata M, Rohla M, Michael N, Neumayr M, et al. Contemporary use of P2Y12-inhibitors in patients with acute coronary syndrome undergoing percutaneous coronary intervention in Austria: A prospective, multi-centre registry. PLoS ONE. 2017;12:e0179349 pubmed publisher
    ..Parameters associated with a presumably higher risk of bleeding and side-effects against the more effective P2Y12 inhibitors were the most prominent factors for the prescription of clopidogrel. ..
  39. Miller T, Liau B, Wallace L, Morton A, Xie Q, Dixit D, et al. Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. 2017;547:355-359 pubmed publisher
  40. Ladenstein R, Potschger U, Pearson A, Brock P, Luksch R, Castel V, et al. Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial. Lancet Oncol. 2017;18:500-514 pubmed publisher
    ..European Commission 5th Framework Grant and the St Anna Kinderkrebsforschung. ..
  41. Pavel M, Singh S, Strosberg J, Bubuteishvili Pacaud L, Degtyarev E, Neary M, et al. Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine tumours (RADIANT-4): a multicentre, randomised, double-blind, placebo-controlled, phas. Lancet Oncol. 2017;18:1411-1422 pubmed publisher
    ..Novartis Pharmaceuticals. ..
  42. Czerny M, Baumer H, Kilo J, Lassnigg A, Hamwi A, Vukovich T, et al. Inflammatory response and myocardial injury following coronary artery bypass grafting with or without cardiopulmonary bypass. Eur J Cardiothorac Surg. 2000;17:737-42 pubmed
    ..Our findings indicate that multiregional warm ischaemia, caused by snaring of the diseased coronary artery, causes considerably less myocardial injury than global cold ischaemia induced by cardioplegic cardiac arrest. ..
  43. Elmadfa I, Kornsteiner M. Fats and fatty acid requirements for adults. Ann Nutr Metab. 2009;55:56-75 pubmed publisher
  44. Mohamad Al Ali B, Ponholzer A, Augustin H, Madersbacher S, Pummer K. The Long-Term Effect of Radical Prostatectomy on Erectile Function, Urinary Continence, and Lower Urinary Tract Symptoms: A Comparison to Age-Matched Healthy Controls. Biomed Res Int. 2017;2017:9615080 pubmed publisher
    ..Healthy men have a higher IPSS presumably due to the presence of bladder outlet obstruction. ..
  45. Worel N, Frank N, Frech C, Fritsch G. Influence of plerixafor on the mobilization of CD34+ cell subpopulations and lymphocyte subtypes. Transfusion. 2017;57:2206-2215 pubmed publisher
    ..Further studies are needed to analyze whether these findings have an impact on clinical outcome. ..
  46. Werkstetter K, Korponay Szabó I, Popp A, Villanacci V, Salemme M, Heilig G, et al. Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice. Gastroenterology. 2017;153:924-935 pubmed publisher
    ..HLA analysis is not required for accurate diagnosis. Clinical Trial Registration no: DRKS00003555. ..
  47. Smolen J, Choe J, Prodanovic N, Niebrzydowski J, Staykov I, Dokoupilova E, et al. Comparing biosimilar SB2 with reference infliximab after 54 weeks of a double-blind trial: clinical, structural and safety results. Rheumatology (Oxford). 2017;56:1771-1779 pubmed publisher
    ..Radiographic progression was comparable at 1 year. (; NCT01936181) and EudraCT (; 2012-005733-37). ..
  48. Windpassinger C, Piard J, Bonnard C, Alfadhel M, Lim S, Bisteau X, et al. CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays. Am J Hum Genet. 2017;101:391-403 pubmed publisher
    ..Our results document the CDK10 loss-of-function phenotype and point to a function for CDK10 in transducing signals received at the primary cilia to sustain embryonic and postnatal development. ..
  49. Blumer R, Streicher J, Davis Lopez de Carrizosa M, de la Cruz R, Pastor A. Palisade Endings of Extraocular Muscles Develop Postnatally Following Different Time Courses. Invest Ophthalmol Vis Sci. 2017;58:5105-5121 pubmed publisher
    ..To analyze in a frontal-eyed mammal (cat) the postnatal development of palisade endings in extraocular muscles (EOMs) and to compare the spatiotemporal and quantitative patterns of palisade endings among individual rectus muscles...
  50. Schwarz C, Fitschek F, Bar Or D, Klaus D, Tudor B, Fleischmann E, et al. Inflammatory response and oxidative stress during liver resection. PLoS ONE. 2017;12:e0185685 pubmed publisher
    ..Postoperative complications are still a major concern after liver resection (LR). Systemic inflammation and deregulated reactive oxygen species during major abdominal surgery may impair outcome after hepatectomy...
  51. Eisterer W, Piringer G, de Vries A, Ofner D, Greil R, Tschmelitsch J, et al. Neoadjuvant Chemotherapy with Capecitabine, Oxaliplatin and Bevacizumab Followed by Concomitant Chemoradiation and Surgical Resection in Locally Advanced Rectal Cancer with High Risk of Recurrence - A Phase II Study. Anticancer Res. 2017;37:2683-2691 pubmed
  52. Zala S, Reitschmidt D, Noll A, Balazs P, Penn D. Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations. PLoS ONE. 2017;12:e0181200 pubmed publisher
    ..This study is the first to systematically compare error rates for automatic ultrasonic vocalization detection methods, and A-MUD and subsequent versions will be made available for the scientific community. ..
  53. González Gil E, Santabárbara J, Ruiz J, Bel Serrat S, Huybrechts I, Pedrero Chamizo R, et al. Ideal cardiovascular health and inflammation in European adolescents: The HELENA study. Nutr Metab Cardiovasc Dis. 2017;27:447-455 pubmed publisher
    ..Improving these health behaviors, and health factors included in the ICHI, could play an important role in CVD prevention. ..
  54. Sykora S, Jindra C, Hofer M, Steinborn R, Brandt S. Equine papillomavirus type 2: An equine equivalent to human papillomavirus 16?. Vet J. 2017;225:3-8 pubmed publisher
    ..The majority of samples contained more E6 than E2 DNA, with E6:E2 ratios ranging between 0.88 and 4.12. Although not statistically significant (P>0.05), this finding suggests that EcPV2 can integrate into the equine host cell genome. ..
  55. Haymerle G, Janik S, Fochtmann A, Pammer J, Schachner H, Nemec L, et al. Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome. PLoS ONE. 2017;12:e0180426 pubmed publisher
    ..002). To our knowledge this is the first study to describe a negative prognostic effect of the MCPyV expression in lymph node metastasis in MCC patients. ..
  56. Wagener N, Edelmann D, Benner A, Zigeuner R, Borgmann H, Wolff I, et al. Outcome of papillary versus clear cell renal cell carcinoma varies significantly in non-metastatic disease. PLoS ONE. 2017;12:e0184173 pubmed publisher
    ..Consequently, there is urgent need to respect histopathological entities and their subtypes, when assigning follow-up or targeted therapy to RCC patients...
  57. Abdel Wahab M, Lahoupe B, Polo A, Zubizarreta E, Adnan R, Johnston P, et al. Assessment of cancer control capacity and readiness: the role of the International Atomic Energy Agency. Lancet Oncol. 2017;18:e587-e594 pubmed publisher
  58. Almeida A, Prebet T, Itzykson R, Ramos F, Al Ali H, Shammo J, et al. Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study. Int J Mol Sci. 2017;18: pubmed publisher
    ..HMAs (10.5 vs. 13.7 months; p = 0.564), but patients with high-risk cytogenetics treated with HMA first-line lived longer (7.5 for ICT vs. 13.3 months; p = 0.039). Our results support the therapeutic value of HMA in AEL. ..
  59. Jawhar M, Schwaab J, Naumann N, Horny H, Sotlar K, Haferlach T, et al. Response and progression on midostaurin in advanced systemic mastocytosis: KIT D816V and other molecular markers. Blood. 2017;130:137-145 pubmed publisher
    ..In midostaurin-treated advSM patients, the complexity and dynamics of mutational profiles significantly affect response, progression, and prognosis. ..
  60. Streit S, Verschoor M, Rodondi N, Bonfim D, Burman R, Collins C, et al. Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries. BMC Geriatr. 2017;17:93 pubmed publisher
    ..Future hypertension trials should also include frail patients to acquire evidence on the efficacy of antihypertensive treatment in oldest-old patients with frailty, with the aim to get evidence-based data for clinical decision-making. ..
  61. Angermann S, Baumann M, Wassertheurer S, Mayer C, Steubl D, Hauser C, et al. Pulse wave velocity is associated with cognitive impairment in hemodialysis patients. Clin Sci (Lond). 2017;131:1483-1493 pubmed publisher
    ..Concerning the underlying pathogenesis of cognitive impairment, current results revealed a potential involvement of arterial stiffness, which has to be further evaluated in future studies. ..
  62. Chan M, Neely M, Roe M, Goodman S, Erlinge D, Cornel J, et al. Temporal Biomarker Profiling Reveals Longitudinal Changes in Risk of Death or Myocardial Infarction in Non-ST-Segment Elevation Acute Coronary Syndrome. Clin Chem. 2017;63:1214-1226 pubmed publisher
    ..10, 95%, CI 1.00-1.20). Temporal changes in NT-proBNP and hs-CRP are quantitatively associated with future cardiovascular events, supporting their role in dynamic risk stratification of NSTEACS. identifier NCT00699998. ..
  63. Haltmayer E, Schwendenwein I, Licka T. Course of serum amyloid A (SAA) plasma concentrations in horses undergoing surgery for injuries penetrating synovial structures, an observational clinical study. BMC Vet Res. 2017;13:137 pubmed publisher
    ..However further studies will be necessary to ascertain its clinical utility. ..
  64. Manent J, Banerjee S, de Matos Simoes R, Zoranovic T, Mitsiades C, Penninger J, et al. Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species. Oncogene. 2017;36:5576-5592 pubmed publisher
    ..Our study has implications for understanding the interplay between perturbations in Ras signalling and autophagy in tumourigenesis, which might inform the development of novel therapeutics targeting Ras-driven cancers. ..
  65. Mangione F, Jatene T, Badr Eslam R, Bergmark B, Gallagher J, Shah P, et al. Usefulness of Intracoronary Brachytherapy for Patients With Resistant Drug-Eluting Stent Restenosis. Am J Cardiol. 2017;120:369-373 pubmed publisher
    ..This approach might be used as an alternative for these patients. ..
  66. Hassel C, Mirand A, Farkas A, Diedrich S, Huemer H, Peigue Lafeuille H, et al. Phylogeography of Coxsackievirus A16 Reveals Global Transmission Pathways and Recent Emergence and Spread of a Recombinant Genogroup. J Virol. 2017;91: pubmed publisher
    ..The results are consistent with our earlier data on EV-A71 and confirm the epidemiological interconnection of Asia and Europe with regard to EV infections. ..
  67. Golob Schwarzl N, Krassnig S, Toeglhofer A, Park Y, Gogg Kamerer M, Vierlinger K, et al. New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors. Eur J Cancer. 2017;83:56-70 pubmed publisher
    ..We noticed engraved differences in the expression pattern between chronic hepatitis B and C, HBV- and HCV-associated HCC and non-virus-related HCC. ..
  68. Sezer O, Beksac M, Hajek R, Sucak G, Cagirgan S, Linkesch W, et al. Effects of single-agent bortezomib as post-transplant consolidation therapy on multiple myeloma-related bone disease: a randomized phase II study. Br J Haematol. 2017;178:61-71 pubmed publisher
    ..4%), nausea (18% vs. 0) and vomiting (16% vs. 0). Compared with observation, bortezomib appeared to have little impact on bone metabolism/health, but was associated with trends for improved myeloma response and survival. ..
  69. Jeryczynski G, Thiele J, Gisslinger B, Wölfler A, Schalling M, Gleiß A, et al. Pre-fibrotic/early primary myelofibrosis vs. WHO-defined essential thrombocythemia: The impact of minor clinical diagnostic criteria on the outcome of the disease. Am J Hematol. 2017;92:885-891 pubmed publisher
  70. Popkirov S, Ayzenberg I, Hahn S, Bauer J, Denno Y, Rieckhoff N, et al. Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis. Acta Neuropathol Commun. 2017;5:40 pubmed publisher
    ..In conclusion, novel onconeural antibodies targeting ROCK2 are associated with paraneoplastic encephalitis and should be screened for when paraneoplastic neurological syndromes, especially in patients with urogenital cancers, occur. ..
  71. Abia W, Warth B, Ezekiel C, Sarkanj B, Turner P, Marko D, et al. Uncommon toxic microbial metabolite patterns in traditionally home-processed maize dish (fufu) consumed in rural Cameroon. Food Chem Toxicol. 2017;107:10-19 pubmed publisher
    ..g. cereulide, PAT and ZEN derivatives (ZEN-cis and ZENsulfate-cis) are reported for the first time in Cameroonian food. ..
  72. Hametner B, Parragh S, Weber T, Wassertheurer S. Wave intensity of aortic root pressure as diagnostic marker of left ventricular systolic dysfunction. PLoS ONE. 2017;12:e0179938 pubmed publisher
    ..These parameters could help to improve the quality of cardiovascular risk stratification or might be used in screening strategies in the general population. ..
  73. Smolen J, Cohen S, Tony H, Scheinberg M, Kivitz A, Balanescu A, et al. A randomised, double-blind trial to demonstrate bioequivalence of GP2013 and reference rituximab combined with methotrexate in patients with active rheumatoid arthritis. Ann Rheum Dis. 2017;76:1598-1602 pubmed publisher
    ..Three-way PK/PD equivalence of GP2013, RTX-EU and RTX-US was demonstrated. Efficacy, safety and immunogenicity profiles were similar between GP2013 and RTX. NCT01274182; Results. ..
  74. Bogunovic H, Montuoro A, Baratsits M, Karantonis M, Waldstein S, Schlanitz F, et al. Machine Learning of the Progression of Intermediate Age-Related Macular Degeneration Based on OCT Imaging. Invest Ophthalmol Vis Sci. 2017;58:BIO141-BIO150 pubmed publisher
    ..Machine learning is expected to accelerate and contribute to the development of new therapeutics that delay the progression of AMD. ..
  75. Schuler A, Kasprian G, Schwartz E, Seidl R, Diogo M, Mitter C, et al. Mens inversus in corpore inverso? Language lateralization in a boy with situs inversus totalis. Brain Lang. 2017;174:9-15 pubmed publisher
    ..Furthermore, cognitive development in situs inversus is normal. To our knowledge, this is the first report of antenatal cerebral origins of structural and functional brain asymmetry in a case of situs inversus totalis. ..
  76. Klimscha S, Waldstein S, Schlegl T, Bogunovic H, Sadeghipour A, Philip A, et al. Spatial Correspondence Between Intraretinal Fluid, Subretinal Fluid, and Pigment Epithelial Detachment in Neovascular Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2017;58:4039-4048 pubmed publisher
    ..These morphological associations may contribute to our understanding of functional deficits in nAMD. ..
  77. Dimopoulos M, Goldschmidt H, Niesvizky R, Joshua D, Chng W, Oriol A, et al. Carfilzomib or bortezomib in relapsed or refractory multiple myeloma (ENDEAVOR): an interim overall survival analysis of an open-label, randomised, phase 3 trial. Lancet Oncol. 2017;18:1327-1337 pubmed publisher
    ..This study is informative for deciding which proteasome inhibitor to use for treating this disease. Onyx Pharmaceuticals Inc, an Amgen Inc subsidiary. ..
  78. Munz M, Willenborg C, Richter G, Jockel Schneider Y, Graetz C, Staufenbiel I, et al. A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis. Hum Mol Genet. 2017;26:2577-2588 pubmed publisher
    ..This study identifies the first shared genetic risk loci of AgP and CP with genome-wide significance and highlights the role of innate and adaptive immunity in the etiology of periodontitis. ..
  79. Kiefer F, Winhofer Y, Iacovazzo D, Korbonits M, Wolfsberger S, Knosp E, et al. PRKAR1A mutation causing pituitary-dependent Cushing disease in a patient with Carney complex. Eur J Endocrinol. 2017;177:K7-K12 pubmed publisher
    ..i>PRKAR1A loss-of-function mutations can rarely lead to ACTH-secreting pituitary adenomas in CNC patients. Pituitary-dependent disease should be considered in the differential diagnosis of Cushing syndrome in CNC patients. ..
  80. Bogunovic H, Waldstein S, Schlegl T, Langs G, Sadeghipour A, Liu X, et al. Prediction of Anti-VEGF Treatment Requirements in Neovascular AMD Using a Machine Learning Approach. Invest Ophthalmol Vis Sci. 2017;58:3240-3248 pubmed publisher
    ..The results of this pilot study are an important step toward image-guided prediction of treatment intervals in the management of neovascular AMD. ..
  81. Geier C, Kraupp S, Bra D, Eibl M, Farmer J, Csomós K, et al. Reduced numbers of circulating group 2 innate lymphoid cells in patients with common variable immunodeficiency. Eur J Immunol. 2017;47:1959-1969 pubmed publisher
  82. Nauta F, Kim J, Patel H, Peterson M, Eckstein H, Khoynezhad A, et al. Early Outcomes of Acute Retrograde Dissection From the International Registry of Acute Aortic Dissection. Semin Thorac Cardiovasc Surg. 2017;29:150-159 pubmed publisher
    ..A subset of patients with acute retrograde AD originating from primary tear in the descending aorta might be managed less invasively with acceptable early results, particularly among those with proximal extension limited to the arch. ..
  83. Eibenberger K, Schmetterer L, Rezar Dreindl S, Wozniak P, Told R, Mylonas G, et al. Effects of Intravitreal Dexamethasone Implants on Retinal Oxygen Saturation, Vessel Diameter, and Retrobulbar Blood Flow Velocity in ME Secondary to RVO. Invest Ophthalmol Vis Sci. 2017;58:5022-5029 pubmed publisher
    ..7 mg dexamethasone implants (Ozurdex) on arterial and venous oxygen saturation, retinal vessel diameter, and retrobulbar blood flow velocity in patients with macular edema (ME) due to retinal vein occlusion (RVO)...
  84. Wöll E, Thaler J, Keil F, Gruenberger B, Hejna M, Eisterer W, et al. Oxaliplatin/Irinotecan/Bevacizumab Followed by Docetaxel/Bevacizumab in Inoperable Locally Advanced or Metastatic Gastric Cancer Patients - AGMT_GASTRIC-3. Anticancer Res. 2017;37:5553-5558 pubmed
  85. Li J, Riedel N, Barrech A, Herr R, Aust B, Mörtl K, et al. Long-Term Effectiveness of a Stress Management Intervention at Work: A 9-Year Follow-Up Study Based on a Randomized Wait-List Controlled Trial in Male Managers. Biomed Res Int. 2017;2017:2853813 pubmed publisher
    ..Short- and medium-term effectiveness (up to 3 years) of individual level stress management interventions (SMI) at work were demonstrated, yet long-term effectiveness remains unexplored. We therefore aimed to address this research gap...
  86. Sinko K, Gruber M, Jagsch R, Roesner I, Baumann A, Wutzl A, et al. Assessment of nasalance and nasality in patients with a repaired cleft palate. Eur Arch Otorhinolaryngol. 2017;274:2845-2854 pubmed publisher
    ..Further studies are warranted to determine the applicability of instrumental nasalance measures in the clinical routine, using discriminative items only. ..
  87. Item C, Farhadi S, Schanzer A, Greber Platzer S. DNA methylated alleles of the phenylalanine hydroxylase promoter remodeled at elevated phenylalanine levels in newborns with hyperphenylalaninemia. Clin Biochem. 2017;50:729-732 pubmed publisher
    ..Our results suggest a specific remodeling of the DNA methylated alleles of the PAH promoter at elevated, but not excess phe levels in diet free newborns with PKU. ..
  88. Blume C, Lechinger J, Santhi N, Del Giudice R, Gnjezda M, Pichler G, et al. Significance of circadian rhythms in severely brain-injured patients: A clue to consciousness?. Neurology. 2017;88:1933-1941 pubmed publisher
    ..Our findings also make a case for circadian rhythms as a target for treatment as well as the application of diagnostic and therapeutic means at times when cognitive performance is expected to peak. ..
  89. Huang A, Yu D, Davis L, Sul J, Tsetsos F, Ramensky V, et al. Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron. 2017;94:1101-1111.e7 pubmed publisher
    ..3, 95% CI [2.6-156.2]; CNTN6 duplications, OR = 10.1, 95% CI [2.3-45.4]). Approximately 1% of TS cases carry one of these CNVs, indicating that rare structural variation contributes significantly to the genetic architecture of TS. ..
  90. Shanmugasundaram B, Aher Y, Aradska J, Ilić M, Daba Feyissa D, Kalaba P, et al. R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity. PLoS ONE. 2017;12:e0179675 pubmed publisher
    ..D1R may play an important regulatory role in these processes. ..
  91. Alberti C, Cochella L. A framework for understanding the roles of miRNAs in animal development. Development. 2017;144:2548-2559 pubmed publisher
    ..This view could help to shed new light on our understanding of miRNA function in development, disease and evolution. ..
  92. Rienmüller A, Buchmann N, Kirschke J, Meyer E, Gempt J, Lehmberg J, et al. Accuracy of CT-navigated pedicle screw positioning in the cervical and upper thoracic region with and without prior anterior surgery and ventral plating. Bone Joint J. 2017;99-B:1373-1380 pubmed publisher