Experts and Doctors on antineoplastic agents in Perth, Western Australia, Australia
Locale: Perth, Western Australia, Australia
Topic: antineoplastic agents
Cummins J, Yovich J, Edirisinghe W, Yovich J. Pituitary down-regulation using leuprolide for the intensive ovulation management of poor prognosis patients having in vitro fertilization (IVF)-related treatments. J In Vitro Fert Embryo Transf. 1989;6:345-52 pubmed
..Pregnancy rates per treatment for the other groups were as follows: elevated age, 27% (9/33), high androgens, 40% (2/5); premature LH surges, 32% (9/28); and poor responders, 17.5% (7/40).(ABSTRACT TRUNCATED AT 250 WORDS) ..
Thomas M, Hodgson M, Loermans S, Hooper J, Endersby R, Bentel J. Transcriptional regulation of the homeobox gene NKX3.1 by all-trans retinoic acid in prostate cancer cells. J Cell Biochem. 2006;99:1409-19 pubmed
..These studies demonstrate that the NKX3.1 gene is a direct target of retinoid receptors and suggest that androgen regulation of NKX3.1 expression is mediated in part by the 3'UTR. ..
McCoy M, Nowak A, Lake R. Chemoimmunotherapy: an emerging strategy for the treatment of malignant mesothelioma. Tissue Antigens. 2009;74:1-10 pubmed publisher
..Here, we discuss the rationale behind combining these two, long considered antagonistic, treatment options in the context of malignant mesothelioma...
Saran U, Arfuso F, Zeps N, Dharmarajan A. Secreted frizzled-related protein 4 expression is positively associated with responsiveness to cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers. BMC Cell Biol. 2012;13:25 pubmed publisher
..This study indicates a role for sFRP4 as a predictive marker of chemosensitivity in ovarian cancer and suggests that this pathway may be worth exploiting for novel therapies. ..
Kodama A, Watanabe H, Tanaka R, Kondo M, Chuang V, Wu Q, et al
. Albumin fusion renders thioredoxin an effective anti-oxidative and anti-inflammatory agent for preventing cisplatin-induced nephrotoxicity. Biochim Biophys Acta. 2014;1840:1152-62 pubmed publisher
..A long acting form of Trx, human serum albumin-Trx (HSA-Trx), was produced by recombinant HSA fusion and its effectiveness in preventing cisplatin nephrotoxicity was examined...
Zhang J, Ahn K, Kim C, Shanmugam M, Siveen K, Arfuso F, et al
. Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model. Antioxid Redox Signal. 2016;24:575-89 pubmed publisher
..Overall, our findings indicate that NL exhibits significant anticancer effects in PCa that may be primarily mediated through the ROS-regulated inhibition of STAT3 signaling cascade. ..
Luo Y, Chen J, Huang K, Lin Y, Chen M, Xu L, et al
. Early evaluation of sunitinib for the treatment of advanced gastroenteropancreatic neuroendocrine neoplasms via CT imaging: RECIST 1.1 or Choi Criteria?. BMC Cancer. 2017;17:154 pubmed publisher
..026) and PD groups (Pâ€‰<â€‰0.001). The Choi criteria appear to be more sensitive and more precise than RECIST 1.1 in assessing the early response of advanced GEP-NENs treated with sunitinib. ..
Finlay J, Wyatt K, Black M. Evaluation of the risks of chemotherapy in dogs with thrombocytopenia. Vet Comp Oncol. 2017;15:151-162 pubmed publisher
..028). The results presented here showed no evidence for an increased risk of gastrointestinal adverse effects or haemorrhage in thrombocytopenic dogs after receiving standard doses of chemotherapy. ..
Cook A, Lesterhuis W, Nowak A, Lake R. Chemotherapy and immunotherapy: mapping the road ahead. Curr Opin Immunol. 2016;39:23-9 pubmed publisher